hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_09252.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NIPBL | Nipped-B-like protein (Delangin) (SCC2 homolog) | 5 | UniProt NCBI |
| MPG | DNA-3-methyladenine glycosylase (EC 3.2.2.21) (3-alkyladenine DNA glycosylase) (3-methyladenine DNA glycosidase) (ADPG) (N-methylpurine-DNA glycosylase) | 5 | UniProt NCBI |
| MAU2 | MAU2 chromatid cohesion factor homolog (MAU-2) (Cohesin loading complex subunit SCC4 homolog) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-2470946 | 7.68942788458e-05 | 1.0 | NIPBL MAU2 | Cohesin Loading onto Chromatin |
| REAC:R-HSA-68884 | 0.000133283416666 | 1.0 | NIPBL MAU2 | Mitotic Telophase/Cytokinesis |
| WP:WP5117 | 0.00019792121349 | 1.0 | NIPBL MAU2 | Cohesin complex Cornelia de Lange syndrome |
| GO:0032116 | 0.000468200720083 | 1.0 | NIPBL MAU2 | SMC loading complex |
| GO:0090694 | 0.000468200720083 | 1.0 | NIPBL MAU2 | Scc2-Scc4 cohesin loading complex |
| GO:0061775 | 0.00140460216025 | 1.0 | NIPBL MAU2 | cohesin loader activity |
| KEGG:04110 | 0.00184110178991 | 1.0 | NIPBL MAU2 | Cell cycle |
| GO:0034086 | 0.0365196561665 | 1.0 | NIPBL MAU2 | maintenance of sister chromatid cohesion |
| GO:0034088 | 0.0365196561665 | 1.0 | NIPBL MAU2 | maintenance of mitotic sister chromatid cohesion |
| WP:WP5119 | 0.0435328773163 | 0.5 | NIPBL | NIPBL role in DNA damage Cornelia de Lange syndrome |
| HP:0031228 | 0.0499436884913 | 0.5 | NIPBL | Abnormal incisura morphology |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NIPBL | MPG | 0.979 | 0.1069 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
| NIPBL | MAU2 | 0.978 | 0.324 | hein_WMM bioplex_WMM bioplex3_WMM hein () Malo fraction |
| MAU2 | MPG | 0.058 | 0.052 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes