hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09259.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LMNB1 | Lamin-B1 | 5 | UniProt NCBI |
| PDE6D | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (GMP-PDE delta) (Protein p17) | 5 | UniProt NCBI |
| FBXO10 | F-box only protein 10 | 5 | UniProt NCBI |
| TBC1D10A | TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein) (Rab27A-GAP-alpha) | 5 | UniProt NCBI |
| LMNB2 | Lamin-B2 | 5 | UniProt NCBI |
| UBL3 | Ubiquitin-like protein 3 (Membrane-anchored ubiquitin-fold protein) (HsMUB) (MUB) (Protein HCG-1) | 4 | UniProt NCBI |
| RAB28 | Ras-related protein Rab-28 | 5 | UniProt NCBI |
| INPP5E | Phosphatidylinositol polyphosphate 5-phosphatase type IV (72 kDa inositol polyphosphate 5-phosphatase) (Inositol polyphosphate-5-phosphatase E) (Phosphatidylinositol 4,5-bisphosphate 5-phosphatase) (EC 3.1.3.36) (Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase) (EC 3.1.3.86) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6741 | 6.1565588648e-05 | 0.285714285714 | PDE6D INPP5E | INPP5E-PDE6D-RPGR complex |
| REAC:R-HSA-5624958 | 0.00011430200373 | 0.285714285714 | PDE6D INPP5E | ARL13B-mediated ciliary trafficking of INPP5E |
| WP:WP4803 | 0.0036650703234 | 0.428571428571 | PDE6D INPP5E RAB28 | Ciliopathies |
| HP:0002335 | 0.0129659395038 | 0.285714285714 | PDE6D INPP5E | Agenesis of cerebellar vermis |
| REAC:R-HSA-5620920 | 0.0390490515953 | 0.285714285714 | PDE6D INPP5E | Cargo trafficking to the periciliary membrane |
| WP:WP4656 | 0.0435709553271 | 0.285714285714 | PDE6D INPP5E | Joubert syndrome |
| HP:0007973 | 0.0457644476584 | 0.285714285714 | PDE6D INPP5E | Retinal dysplasia |
| WP:WP5234 | 0.0499136541057 | 0.285714285714 | PDE6D INPP5E | Bardet Biedl syndrome |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| UBL3 | PDE6D | 0.999 | 0.058 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| LMNB1 | LMNB2 | 0.999 | 0.636 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| PDE6D | INPP5E | 0.998 | bioplex3_HEK293 bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM WMM_only | |
| PDE6D | FBXO10 | 0.998 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PDE6D | RAB28 | 0.998 | 0.174 | bioplex3_HEK293 bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM WMM_only |
| PDE6D | TBC1D10A | 0.997 | 0.06 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| LMNB1 | PDE6D | 0.978 | 0.174255319149 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| LMNB2 | PDE6D | 0.974 | 0.108 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| INPP5E | RAB28 | 0.946 | bioplex3_WMM WMM_only | |
| TBC1D10A | INPP5E | 0.931 | bioplex3_WMM WMM_only | |
| UBL3 | INPP5E | 0.923 | bioplex3_WMM WMM_only | |
| TBC1D10A | RAB28 | 0.826 | 0.116 | bioplex3_WMM WMM_only |
| FBXO10 | TBC1D10A | 0.77 | bioplex3_WMM WMM_only | |
| FBXO10 | INPP5E | 0.757 | bioplex3_WMM WMM_only | |
| UBL3 | FBXO10 | 0.734 | bioplex3_WMM WMM_only | |
| FBXO10 | RAB28 | 0.72 | bioplex3_WMM WMM_only | |
| UBL3 | TBC1D10A | 0.72 | 0.076 | bioplex3_WMM WMM_only |
| UBL3 | RAB28 | 0.527 | 0.114 | bioplex3_WMM WMM_only |
| LMNB2 | RAB28 | 0.287 | 0.228 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| LMNB2 | FBXO10 | 0.251 | 0.076 | bioplex3_HEK293 bioplex3_WMM WMM_only |
| LMNB2 | INPP5E | 0.244 | bioplex3_WMM WMM_only | |
| UBL3 | LMNB2 | 0.213 | 0.14 | bioplex_WMM bioplex3_WMM WMM_only |
| LMNB2 | TBC1D10A | 0.205 | 0.086 | bioplex3_WMM WMM_only |
| LMNB1 | INPP5E | 0.159 | bioplex3_WMM WMM_only | |
| LMNB1 | TBC1D10A | 0.124 | 0.190413043478 | bioplex_WMM bioplex3_WMM WMM_only |
| LMNB1 | RAB28 | 0.044 | 0.248413043478 | bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| UBL3 | LMNB1 | 0.043 | 0.164 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
| LMNB1 | FBXO10 | 0.023 | 0.114 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes