hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09270.1
Complex Portal: CPX-16785
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GLB1L2 | Beta-galactosidase-1-like protein 2 (EC 3.2.1.-) | 3 | UniProt NCBI |
| ST8SIA3 | Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase ST8SIA3 (EC 2.4.3.-) (Alpha-2,8-sialyltransferase 8C) (Alpha-2,8-sialyltransferase III) (Ganglioside GD3 synthase ST8SIA3) (EC 2.4.3.8) (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3) (Sia-a2,3-Gal-b1,4-Glc-NAc-R:a2,8-sialyltransferase) (hST8Sia III) (Sialyltransferase 8C) (SIAT8-C) (Sialyltransferase St8Sia III) (ST8SiaIII) | 5 | UniProt NCBI |
| DCT | L-dopachrome tautomerase (DCT) (DT) (EC 5.3.3.12) (L-dopachrome Delta-isomerase) (Tyrosinase-related protein 2) (TRP-2) (TRP2) | 5 | UniProt NCBI |
| ITPRIP | Inositol 1,4,5-trisphosphate receptor-interacting protein (Protein DANGER) | 5 | UniProt NCBI |
| ST8SIA5 | Alpha-2,8-sialyltransferase 8E (EC 2.4.99.-) (Sialyltransferase 8E) (SIAT8-E) (Sialyltransferase St8Sia V) (ST8SiaV) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP1423 | 0.0003876755558 | 0.4 | ST8SIA5 ST8SIA3 | Ganglio sphingolipid metabolism |
| REAC:R-HSA-4085001 | 0.0065872694687 | 0.4 | ST8SIA5 ST8SIA3 | Sialic acid metabolism |
| REAC:R-HSA-446219 | 0.0249357389386 | 0.4 | ST8SIA5 ST8SIA3 | Synthesis of substrates in N-glycan biosythesis |
| REAC:R-HSA-446193 | 0.0395622673154 | 0.4 | ST8SIA5 ST8SIA3 | Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| DCT | GLB1L2 | 0.979 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| GLB1L2 | ST8SIA3 | 0.979 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ITPRIP | ST8SIA5 | 0.978 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| GLB1L2 | ST8SIA5 | 0.962 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ITPRIP | GLB1L2 | 0.95 | 0.096 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes