hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09271.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| AMH | Muellerian-inhibiting factor (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance) (MIS) | 5 | UniProt NCBI |
| SGK3 | Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like) | 5 | UniProt NCBI |
| PKN3 | Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN-beta) (Protein-kinase C-related kinase 3) | 5 | UniProt NCBI |
| AMHR2 | Anti-Muellerian hormone type-2 receptor (EC 2.7.11.30) (Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIS type II receptor) (MISRII) (MRII) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4842 | 0.000306067313039 | 0.5 | AMH AMHR2 | Mammalian disorder of sexual development |
| HP:0031103 | 0.000501460556964 | 0.5 | AMH AMHR2 | Decreased cirrculating antimullerian hormone circulation |
| HP:0031101 | 0.000701980712879 | 0.5 | AMH AMHR2 | Abnormal circulating antimullerian hormone concentration |
| GO:0001880 | 0.0028092043205 | 0.5 | AMH AMHR2 | Mullerian duct regression |
| REAC:R-HSA-201451 | 0.00306932002175 | 0.5 | AMH AMHR2 | Signaling by BMP |
| GO:1990262 | 0.00842684400117 | 0.5 | AMH AMHR2 | anti-Mullerian hormone signaling pathway |
| KEGG:04350 | 0.00931062778609 | 0.5 | AMH AMHR2 | TGF-beta signaling pathway |
| HP:0000037 | 0.0155098335254 | 0.5 | AMH AMHR2 | Male pseudohermaphroditism |
| WP:WP5316 | 0.0208408229239 | 0.5 | AMH AMHR2 | Primary ovarian insufficiency |
| HP:0008689 | 0.0329787201379 | 0.5 | AMH AMHR2 | Bilateral cryptorchidism |
| GO:0060033 | 0.042122686785 | 0.5 | AMH AMHR2 | anatomical structure regression |
| KEGG:04060 | 0.0475663770677 | 0.5 | AMH AMHR2 | Cytokine-cytokine receptor interaction |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SGK3 | AMHR2 | 1.0 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| AMHR2 | PKN3 | 0.989 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| AMH | AMHR2 | 0.988 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| SGK3 | PKN3 | 0.696 | 0.082 | bioplex3_WMM WMM_only |
| AMH | SGK3 | 0.278 | bioplex3_WMM WMM_only | |
| AMH | PKN3 | 0.076 | bioplex3_WMM WMM_only |
Related Complexes