hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09275.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SFPQ | Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor) | 5 | UniProt NCBI |
| PSPC1 | Paraspeckle component 1 (Paraspeckle protein 1) | 5 | UniProt NCBI |
| NONO | Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7285 | 2.56314262819e-05 | 1.0 | PSPC1 NONO | HEXIM1-DNA-PK-paraspeckle components-ribonucleoprotein complex |
| WP:WP3594 | 0.00534642658633 | 1.0 | PSPC1 NONO | Circadian rhythm genes |
| GO:0042382 | 0.0210690324038 | 1.0 | PSPC1 NONO | paraspeckles |
| HPA:0050013 | 0.0240136418168 | 1.0 | PSPC1 NONO | breast; adipocytes[High] |
| CORUM:330 | 0.0249718442457 | 0.5 | NONO | PSF-p54(nrb) complex |
| CORUM:1760 | 0.0249718442457 | 0.5 | NONO | TOP1-PSF-P54 complex |
| HPA:0100203 | 0.0426532059597 | 1.0 | PSPC1 NONO | cerebral cortex; endothelial cells[High] |
| CORUM:335 | 0.0499419797295 | 0.5 | NONO | p54(nrb)-PSF-matrin3 complex |
| HP:0031713 | 0.0499436884913 | 0.5 | NONO | Constant exotropia |
| HP:0032009 | 0.0499436884913 | 0.5 | NONO | Infantile constant exotropia |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NONO | SFPQ | 1.0 | 0.992 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt Malo bioplex3_HCT116 fraction boldt_WMM treiber_WMM |
| PSPC1 | NONO | 1.0 | 0.62 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 fraction boldt_WMM treiber_WMM |
| PSPC1 | SFPQ | 0.999 | 0.674 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 fraction boldt_WMM treiber_WMM |
Related Complexes