hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_09289.1

Confidence: Moderate High

Genename	Protein Name	Uniprot Annotation Score	Links
TLK1	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (PKU-beta) (Tousled-like kinase 1)	5	UniProt NCBI
CDIN1	CDAN1-interacting nuclease 1 (Protein HH114)	5	UniProt NCBI
PAN2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (EC 3.1.13.4) (Inactive ubiquitin carboxyl-terminal hydrolase 52) (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 2) (PAN deadenylation complex subunit 2)	5	UniProt NCBI
UBN2	Ubinuclein-2	3	UniProt NCBI
IPO4	Importin-4 (Imp4) (Importin-4b) (Imp4b) (Ran-binding protein 4) (RanBP4)	5	UniProt NCBI
ASF1A	Histone chaperone ASF1A (Anti-silencing function protein 1 homolog A) (hAsf1) (hAsf1a) (CCG1-interacting factor A) (CIA) (hCIA)	5	UniProt NCBI
PAN3	PAN2-PAN3 deadenylation complex subunit PAN3 (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 3) (PAN deadenylation complex subunit 3)	5	UniProt NCBI
HIRA	Protein HIRA (TUP1-like enhancer of split protein 1)	5	UniProt NCBI
CDAN1	Codanin-1	5	UniProt NCBI
SPATA1	Spermatogenesis-associated protein 1 (Sperm-specific protein SP-2)	3	UniProt NCBI
ASF1B	Histone chaperone ASF1B (Anti-silencing function protein 1 homolog B) (hAsf1) (hAsf1b) (CCG1-interacting factor A-II) (CIA-II) (hCIA-II)	5	UniProt NCBI
TLK2	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (HsHPK) (PKU-alpha) (Tousled-like kinase 2)	5	UniProt NCBI
CABIN1	Calcineurin-binding protein cabin-1 (Calcineurin inhibitor) (CAIN)	5	UniProt NCBI
UBN1	Ubinuclein-1 (HIRA-binding protein) (Protein VT4) (Ubiquitously expressed nuclear protein)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:1150	7.3876470612e-10	0.307692307692	IPO4 ASF1B ASF1A HIRA	Histone H3.3 complex
CORUM:6149	3.08880131998e-08	0.230769230769	IPO4 ASF1A CDAN1	Codanin-1-Asf1-histone H3.1-histone H4-importin-4 complex, cytosolic
CORUM:7382	1.23488636402e-07	0.230769230769	CABIN1 HIRA UBN1	Prohibitin-HIRA complex
CORUM:7383	1.23488636402e-07	0.230769230769	CABIN1 HIRA UBN1	OGT-HIRA complex
REAC:R-HSA-2559584	1.39571499338e-07	0.307692307692	CABIN1 UBN1 ASF1A HIRA	Formation of Senescence-Associated Heterochromatin Foci (SAHF)
CORUM:2235	3.08563128138e-07	0.230769230769	ASF1B ASF1A HIRA	ASF1-interacting protein complex
CORUM:1149	1.72529396443e-06	0.230769230769	IPO4 ASF1A ASF1B	Histone H3.1 complex
GO:0006325	4.65968938697e-05	0.615384615385	TLK2 TLK1 CDAN1 ASF1A HIRA CABIN1 ASF1B UBN1	chromatin organization
REAC:R-HSA-2559586	7.63868795464e-05	0.307692307692	CABIN1 UBN1 ASF1A HIRA	DNA Damage/Telomere Stress Induced Senescence
GO:0071824	0.000148816711032	0.615384615385	TLK2 TLK1 CDAN1 ASF1A HIRA CABIN1 ASF1B UBN1	protein-DNA complex organization
GO:0006334	0.000286779915289	0.384615384615	CABIN1 UBN1 ASF1B ASF1A HIRA	nucleosome assembly
CORUM:2236	0.000614265253436	0.153846153846	ASF1A ASF1B	ASF1-histone containing complex
GO:0034728	0.000754221961012	0.384615384615	CABIN1 UBN1 ASF1B ASF1A HIRA	nucleosome organization
REAC:R-HSA-2559583	0.00356657683455	0.307692307692	CABIN1 UBN1 ASF1A HIRA	Cellular Senescence
GO:0065004	0.0100164432278	0.384615384615	CABIN1 UBN1 ASF1B ASF1A HIRA	protein-DNA complex assembly
GO:0031251	0.0365196561665	0.153846153846	PAN3 PAN2	PAN complex

Edges

Protein 1	Protein 2	Score	ProteomeHD
ASF1A	HIRA	1.0	0.086
HIRA	ASF1B	1.0	0.054
UBN2	ASF1A	1.0	0.09
CABIN1	ASF1A	1.0	0.032
TLK1	TLK2	1.0	0.122
IPO4	ASF1A	0.999	0.05
IPO4	ASF1B	0.999	0.074
TLK1	ASF1B	0.999	0.044
TLK1	ASF1A	0.999	0.086
CABIN1	HIRA	0.999	0.252
ASF1A	UBN1	0.999	0.07
ASF1A	PAN3	0.999	0.056
ASF1A	PAN2	0.998	0.068
UBN2	HIRA	0.998	0.266
CABIN1	ASF1B	0.997	0.03
ASF1A	CDAN1	0.997	0.114
UBN2	ASF1B	0.997	0.096
ASF1B	TLK2	0.997	0.038
CABIN1	UBN2	0.997	0.174
ASF1B	UBN1	0.997	0.036
ASF1A	TLK2	0.996	0.038
PAN2	PAN3	0.996	0.19
CDIN1	ASF1A	0.994	0.114
SPATA1	TLK2	0.991
ASF1A	ASF1B	0.991	0.136
CDAN1	ASF1B	0.991	0.088
TLK1	SPATA1	0.991
ASF1B	PAN3	0.983	0.024
CDIN1	ASF1B	0.982	0.044
HIRA	UBN1	0.975	0.404
UBN2	UBN1	0.972	0.094
TLK1	HIRA	0.956	0.124
ASF1B	PAN2	0.951	0.032
CABIN1	TLK2	0.917	0.062
HIRA	TLK2	0.907	0.154
TLK1	UBN1	0.894	0.158
CABIN1	UBN1	0.884	0.124
UBN1	TLK2	0.82	0.134
UBN2	TLK2	0.809	0.12
TLK1	CABIN1	0.806	0.056
TLK1	UBN2	0.806	0.154
CDIN1	CDAN1	0.802	0.098
IPO4	HIRA	0.794	0.144
TLK1	CDAN1	0.772	0.13
CDAN1	PAN2	0.756	0.09
TLK1	CDIN1	0.72	0.19
CABIN1	PAN2	0.704	0.088
CDAN1	TLK2	0.698	0.076
UBN1	PAN2	0.669	0.066
TLK1	IPO4	0.65	0.016
CABIN1	CDAN1	0.648	0.068
CDAN1	UBN1	0.645	0.04
CDIN1	UBN1	0.634	0.122
UBN2	CDAN1	0.634	0.072
CDAN1	PAN3	0.608	0.096
CDIN1	TLK2	0.583	0.092
CDIN1	PAN2	0.58	0.104
PAN2	TLK2	0.564	0.118
HIRA	PAN2	0.564	0.148
CDIN1	CABIN1	0.563	0.162
CDIN1	UBN2	0.549	0.092
TLK1	PAN2	0.533	0.076
CABIN1	PAN3	0.526	0.216
TLK1	PAN3	0.525	0.084
CDIN1	PAN3	0.525	0.14
UBN1	PAN3	0.511	0.184
IPO4	UBN1	0.496	0.06
HIRA	PAN3	0.461	0.232
HIRA	CDAN1	0.425	0.082
CDIN1	HIRA	0.37	0.084
UBN2	PAN2	0.34	0.134
IPO4	PAN2	0.231	0.044
IPO4	CDAN1	0.194	0.104
IPO4	TLK2	0.193	0.042
UBN2	PAN3	0.192	0.098
CDIN1	IPO4	0.181	0.07
PAN3	TLK2	0.176	0.16
CABIN1	IPO4	0.157	0.052
UBN2	IPO4	0.116	0.066
IPO4	PAN3	0.073	0.072

Related Complexes

Genename	Complexes
TLK1	huMAP3_00115.1 huMAP3_01778.1 huMAP3_01879.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_10933.1 huMAP3_12566.1 huMAP3_12711.1 huMAP3_12963.1
CDIN1	huMAP3_00115.1 huMAP3_00724.1 huMAP3_06020.1 huMAP3_06779.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_11832.1 huMAP3_11834.1 huMAP3_12711.1 huMAP3_12963.1
PAN2	huMAP3_00724.1 huMAP3_05456.1 huMAP3_08143.1 huMAP3_08866.1 huMAP3_09289.1 huMAP3_09764.1 huMAP3_09859.1 huMAP3_11834.1 huMAP3_12015.1 huMAP3_12538.1 huMAP3_12711.1 huMAP3_12963.1 huMAP3_13022.1 huMAP3_15185.1
UBN2	huMAP3_00115.1 huMAP3_00724.1 huMAP3_01912.1 huMAP3_05517.1 huMAP3_06020.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_11745.1 huMAP3_11834.1 huMAP3_12711.1 huMAP3_12963.1
IPO4	huMAP3_00115.1 huMAP3_00724.1 huMAP3_03330.1 huMAP3_05068.1 huMAP3_05517.1 huMAP3_06020.1 huMAP3_06779.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09575.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_10785.1 huMAP3_12711.1 huMAP3_14135.1 huMAP3_14456.1
ASF1A	huMAP3_00115.1 huMAP3_00724.1 huMAP3_05517.1 huMAP3_06020.1 huMAP3_06779.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_11834.1 huMAP3_12711.1 huMAP3_12963.1
PAN3	huMAP3_00724.1 huMAP3_02330.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09764.1 huMAP3_09859.1 huMAP3_11834.1 huMAP3_12015.1 huMAP3_12538.1 huMAP3_12711.1 huMAP3_12963.1 huMAP3_13022.1 huMAP3_15185.1
HIRA	huMAP3_00115.1 huMAP3_00724.1 huMAP3_01912.1 huMAP3_05517.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_11834.1 huMAP3_12711.1 huMAP3_12963.1
CDAN1	huMAP3_00115.1 huMAP3_00724.1 huMAP3_06020.1 huMAP3_06779.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_11834.1 huMAP3_12711.1 huMAP3_12963.1
SPATA1	huMAP3_01537.1 huMAP3_01778.1 huMAP3_01879.1 huMAP3_05664.1 huMAP3_06772.1 huMAP3_09289.1 huMAP3_10933.1 huMAP3_11465.1 huMAP3_12566.1 huMAP3_12711.1 huMAP3_12963.1
ASF1B	huMAP3_00115.1 huMAP3_00724.1 huMAP3_05517.1 huMAP3_06020.1 huMAP3_06779.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_11834.1 huMAP3_12711.1 huMAP3_12963.1
TLK2	huMAP3_01778.1 huMAP3_01879.1 huMAP3_04345.1 huMAP3_05467.1 huMAP3_06772.1 huMAP3_09289.1 huMAP3_10849.1 huMAP3_10933.1 huMAP3_11834.1 huMAP3_12566.1 huMAP3_12711.1 huMAP3_12963.1
CABIN1	huMAP3_00115.1 huMAP3_00724.1 huMAP3_01912.1 huMAP3_05517.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_11834.1 huMAP3_12711.1 huMAP3_12963.1
UBN1	huMAP3_00115.1 huMAP3_00724.1 huMAP3_01912.1 huMAP3_05517.1 huMAP3_06020.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_11834.1 huMAP3_12711.1 huMAP3_12963.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_09289.1