hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_09311.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FOXK2 | Forkhead box protein K2 (G/T-mismatch specific binding protein) (nGTBP) (Interleukin enhancer-binding factor 1) | 5 | UniProt NCBI |
| BRMS1 | Breast cancer metastasis-suppressor 1 | 5 | UniProt NCBI |
| BRMS1L | Breast cancer metastasis-suppressor 1-like protein (BRMS1-homolog protein p40) (BRMS1-like protein p40) | 5 | UniProt NCBI |
| SAP130 | Histone deacetylase complex subunit SAP130 (130 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p130) | 5 | UniProt NCBI |
| SAP30 | Histone deacetylase complex subunit SAP30 (30 kDa Sin3-associated polypeptide) (Sin3 corepressor complex subunit SAP30) (Sin3-associated polypeptide p30) | 5 | UniProt NCBI |
| TGIF2LX | Homeobox protein TGIF2LX (TGF-beta-induced transcription factor 2-like protein) (TGFB-induced factor 2-like protein, X-linked) (TGIF-like on the X) | 4 | UniProt NCBI |
| ING2 | Inhibitor of growth protein 2 (Inhibitor of growth 1-like protein) (ING1Lp) (p32) (p33ING2) | 5 | UniProt NCBI |
| TNRC18 | Trinucleotide repeat-containing gene 18 protein (Long CAG trinucleotide repeat-containing gene 79 protein) | 4 | UniProt NCBI |
| SINHCAF | SIN3-HDAC complex-associated factor (Protein FAM60A) (Tera protein homolog) | 5 | UniProt NCBI |
| TGIF2 | Homeobox protein TGIF2 (5'-TG-3'-interacting factor 2) (TGF-beta-induced transcription factor 2) (TGFB-induced factor 2) | 5 | UniProt NCBI |
| ARID4A | AT-rich interactive domain-containing protein 4A (ARID domain-containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1) | 5 | UniProt NCBI |
| BAHCC1 | BAH and coiled-coil domain-containing protein 1 (Bromo adjacent homology domain-containing protein 2) (BAH domain-containing protein 2) | 3 | UniProt NCBI |
| PDGFRB | Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b) | 5 | UniProt NCBI |
| ARID4B | AT-rich interactive domain-containing protein 4B (ARID domain-containing protein 4B) (180 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p180) (Breast cancer-associated antigen BRCAA1) (Histone deacetylase complex subunit SAP180) (Retinoblastoma-binding protein 1-like 1) | 5 | UniProt NCBI |
| FOXK1 | Forkhead box protein K1 (Myocyte nuclear factor) (MNF) | 5 | UniProt NCBI |
| ING1 | Inhibitor of growth protein 1 | 5 | UniProt NCBI |
| SIN3A | Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a) | 5 | UniProt NCBI |
| SAP30L | Histone deacetylase complex subunit SAP30L (HCV non-structural protein 4A-transactivated protein 2) (Sin3 corepressor complex subunit SAP30L) (Sin3-associated protein p30-like) | 5 | UniProt NCBI |
| TERT | Telomerase reverse transcriptase (EC 2.7.7.49) (HEST2) (Telomerase catalytic subunit) (Telomerase-associated protein 2) (TP2) | 5 | UniProt NCBI |
| SUDS3 | Sin3 histone deacetylase corepressor complex component SDS3 (45 kDa Sin3-associated polypeptide) (Suppressor of defective silencing 3 protein homolog) | 5 | UniProt NCBI |
| SIN3B | Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:1902455 | 3.63023040961e-23 | 0.55 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A ING2 | negative regulation of stem cell population maintenance |
| GO:1902459 | 6.13663302877e-20 | 0.55 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A ING2 | positive regulation of stem cell population maintenance |
| GO:2000036 | 4.83759213273e-18 | 0.55 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A ING2 | regulation of stem cell population maintenance |
| GO:0030512 | 3.09621840126e-17 | 0.55 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A ING2 | negative regulation of transforming growth factor beta receptor signaling pathway |
| CORUM:2851 | 3.298273953e-17 | 0.35 | BRMS1 ING2 SAP130 BRMS1L SUDS3 SIN3A SAP30 | ING2 complex |
| GO:0098727 | 1.80934173325e-15 | 0.55 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A ING2 | maintenance of cell number |
| GO:0019827 | 1.80934173325e-15 | 0.55 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A ING2 | stem cell population maintenance |
| GO:0090101 | 4.35190669663e-15 | 0.55 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A ING2 | negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway |
| GO:0017015 | 6.20972273762e-15 | 0.55 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A ING2 | regulation of transforming growth factor beta receptor signaling pathway |
| GO:1903844 | 6.20972273762e-15 | 0.55 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A ING2 | regulation of cellular response to transforming growth factor beta stimulus |
| GO:0030336 | 1.47205303556e-13 | 0.6 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SIN3B SUDS3 ING1 SAP30 SIN3A ING2 | negative regulation of cell migration |
| GO:2000146 | 2.54299224559e-13 | 0.6 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SIN3B SUDS3 ING1 SAP30 SIN3A ING2 | negative regulation of cell motility |
| GO:0007179 | 6.60471519999e-13 | 0.55 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A ING2 | transforming growth factor beta receptor signaling pathway |
| GO:0040013 | 7.07145316823e-13 | 0.6 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SIN3B SUDS3 ING1 SAP30 SIN3A ING2 | negative regulation of locomotion |
| GO:0071560 | 2.91921237859e-12 | 0.55 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A ING2 | cellular response to transforming growth factor beta stimulus |
| GO:0090092 | 3.79093267053e-12 | 0.55 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A ING2 | regulation of transmembrane receptor protein serine/threonine kinase signaling pathway |
| GO:0045892 | 3.84532187895e-12 | 0.8 | BRMS1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B ING1 TGIF2 SAP30 SUDS3 SIN3A FOXK1 SINHCAF | negative regulation of DNA-templated transcription |
| GO:0071559 | 4.04289508938e-12 | 0.55 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A ING2 | response to transforming growth factor beta |
| GO:1902679 | 4.61653503936e-12 | 0.8 | BRMS1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B ING1 TGIF2 SAP30 SUDS3 SIN3A FOXK1 SINHCAF | negative regulation of RNA biosynthetic process |
| CORUM:592 | 1.2795612291e-11 | 0.25 | SAP130 SUDS3 SIN3A ARID4B SAP30 | SAP complex (Sin3-associated protein complex) |
| GO:0090287 | 2.01556945916e-11 | 0.55 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A ING2 | regulation of cellular response to growth factor stimulus |
| GO:0051253 | 2.18547361338e-11 | 0.8 | BRMS1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B ING1 TGIF2 SAP30 SUDS3 SIN3A FOXK1 SINHCAF | negative regulation of RNA metabolic process |
| CORUM:743 | 2.55693262895e-11 | 0.25 | SAP130 SUDS3 SIN3A ARID4B SAP30 | SIN3-SAP25 complex |
| CORUM:691 | 2.55693262895e-11 | 0.25 | SAP130 SUDS3 SIN3A ARID4B SAP30 | SIN3-SAP25 complex |
| GO:0141091 | 5.49092456921e-11 | 0.55 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A ING2 | transforming growth factor beta receptor superfamily signaling pathway |
| GO:0000122 | 7.41567307846e-11 | 0.7 | BRMS1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B ARID4B ING1 TGIF2 SAP30 SUDS3 SIN3A SINHCAF | negative regulation of transcription by RNA polymerase II |
| GO:0007178 | 9.88569192885e-11 | 0.55 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A ING2 | transmembrane receptor protein serine/threonine kinase signaling pathway |
| GO:0045934 | 1.07337826143e-10 | 0.8 | BRMS1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B ING1 TGIF2 SAP30 SUDS3 SIN3A FOXK1 SINHCAF | negative regulation of nucleobase-containing compound metabolic process |
| GO:0010558 | 5.9721631866e-10 | 0.85 | BRMS1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B ING1 TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | negative regulation of macromolecule biosynthetic process |
| GO:0031327 | 8.69819653359e-10 | 0.85 | BRMS1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B ING1 TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | negative regulation of cellular biosynthetic process |
| GO:0071363 | 9.546058982e-10 | 0.6 | BRMS1 ING1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 PDGFRB SAP30 SIN3A ING2 | cellular response to growth factor stimulus |
| GO:0009890 | 9.59472661228e-10 | 0.85 | BRMS1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B ING1 TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | negative regulation of biosynthetic process |
| GO:0070848 | 1.42991630967e-09 | 0.6 | BRMS1 ING1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 PDGFRB SAP30 SIN3A ING2 | response to growth factor |
| GO:0030334 | 3.99667234457e-09 | 0.65 | BRMS1 ING1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SIN3B SUDS3 PDGFRB SAP30 SIN3A ING2 | regulation of cell migration |
| CORUM:696 | 6.49102014914e-09 | 0.2 | BRMS1 SIN3A SIN3B SAP30 | BRMS1-SIN3-HDAC complex |
| CORUM:591 | 6.49102014914e-09 | 0.2 | SAP130 SIN3A ARID4B SAP30 | SAP complex (Sin3-associated protein complex) |
| REAC:R-HSA-427413 | 8.15926663515e-09 | 0.35 | SAP130 SAP30L SUDS3 SIN3B ARID4B SIN3A SAP30 | NoRC negatively regulates rRNA expression |
| GO:2000145 | 8.70779778755e-09 | 0.65 | BRMS1 ING1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SIN3B SUDS3 PDGFRB SAP30 SIN3A ING2 | regulation of cell motility |
| REAC:R-HSA-5250941 | 1.02160554976e-08 | 0.35 | SAP130 SAP30L SUDS3 SIN3B ARID4B SIN3A SAP30 | Negative epigenetic regulation of rRNA expression |
| CORUM:738 | 1.16735997786e-08 | 0.2 | SAP30 SIN3A ARID4B ING1 | SIN3-ING1b complex I |
| GO:0040012 | 1.18233128964e-08 | 0.65 | BRMS1 ING1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SIN3B SUDS3 PDGFRB SAP30 SIN3A ING2 | regulation of locomotion |
| GO:0070822 | 1.75299888387e-08 | 0.25 | BRMS1 SUDS3 SIN3A SAP130 BRMS1L | Sin3-type complex |
| GO:0031324 | 1.78971068975e-08 | 0.85 | BRMS1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B ING1 TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | negative regulation of cellular metabolic process |
| GO:0010605 | 2.4512405384e-08 | 0.85 | BRMS1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B ING1 TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | negative regulation of macromolecule metabolic process |
| GO:0051172 | 3.48553339297e-08 | 0.8 | BRMS1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B ING1 TGIF2 SAP30 SUDS3 SIN3A FOXK1 SINHCAF | negative regulation of nitrogen compound metabolic process |
| GO:0040011 | 7.4335009925e-08 | 0.65 | BRMS1 ING1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SIN3B SUDS3 PDGFRB SAP30 SIN3A ING2 | locomotion |
| GO:0000118 | 8.16168098865e-08 | 0.35 | BRMS1 SAP30L BRMS1L SUDS3 SIN3A SAP30 SAP130 | histone deacetylase complex |
| GO:0009892 | 8.98504415907e-08 | 0.85 | BRMS1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B ING1 TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | negative regulation of metabolic process |
| CORUM:739 | 1.6758717745e-07 | 0.2 | SAP30 SIN3A ARID4B ING1 | SIN3-ING1b complex II |
| CORUM:2721 | 1.6758717745e-07 | 0.2 | SAP30 SIN3A SIN3B SUDS3 | HCF-1 complex |
| GO:0006357 | 1.91930129774e-07 | 0.8 | BRMS1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B ING1 TGIF2 SAP30 SUDS3 SIN3A FOXK1 SINHCAF | regulation of transcription by RNA polymerase II |
| GO:0007167 | 2.0141120077e-07 | 0.6 | BRMS1 ING1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 PDGFRB SAP30 SIN3A ING2 | enzyme-linked receptor protein signaling pathway |
| GO:0051093 | 3.08028907092e-07 | 0.55 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A ING2 | negative regulation of developmental process |
| GO:0006366 | 4.39365196353e-07 | 0.8 | BRMS1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B ING1 TGIF2 SAP30 SUDS3 SIN3A FOXK1 SINHCAF | transcription by RNA polymerase II |
| REAC:R-HSA-212165 | 5.62130742092e-07 | 0.35 | SAP130 SAP30L SUDS3 SIN3B ARID4B SIN3A SAP30 | Epigenetic regulation of gene expression |
| GO:0034654 | 6.30143200088e-07 | 0.9 | BRMS1 ING1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B PDGFRB TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | nucleobase-containing compound biosynthetic process |
| GO:0016477 | 7.76045675611e-07 | 0.65 | BRMS1 ING1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SIN3B SUDS3 PDGFRB SAP30 SIN3A ING2 | cell migration |
| GO:0006355 | 8.03532871551e-07 | 0.85 | BRMS1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B ING1 TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | regulation of DNA-templated transcription |
| GO:0018130 | 8.68424563011e-07 | 0.9 | BRMS1 ING1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B PDGFRB TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | heterocycle biosynthetic process |
| GO:0019438 | 8.8479909828e-07 | 0.9 | BRMS1 ING1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B PDGFRB TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | aromatic compound biosynthetic process |
| GO:2001141 | 8.87941057549e-07 | 0.85 | BRMS1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B ING1 TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | regulation of RNA biosynthetic process |
| GO:0019219 | 8.90321549119e-07 | 0.9 | BRMS1 ING1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B PDGFRB TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | regulation of nucleobase-containing compound metabolic process |
| GO:1901362 | 1.47173876976e-06 | 0.9 | BRMS1 ING1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B PDGFRB TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | organic cyclic compound biosynthetic process |
| GO:0006351 | 1.75642428787e-06 | 0.85 | BRMS1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B ING1 TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | DNA-templated transcription |
| GO:0032774 | 2.09473276059e-06 | 0.85 | BRMS1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B ING1 TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | RNA biosynthetic process |
| CORUM:695 | 2.78965060279e-06 | 0.15 | SAP30 ARID4B SIN3A | SIN3-HDAC-SAP30-ARID4 complex |
| CORUM:596 | 2.78965060279e-06 | 0.15 | SAP30 ARID4B SIN3A | SIN3-HDAC-SAP30-ARID4 complex |
| CORUM:698 | 2.78965060279e-06 | 0.15 | SAP30 ARID4B SIN3A | SIN3-HDAC-SAP30-ARID4 complex |
| GO:0048870 | 3.04923244788e-06 | 0.65 | BRMS1 ING1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SIN3B SUDS3 PDGFRB SAP30 SIN3A ING2 | cell motility |
| GO:0051241 | 4.90532303473e-06 | 0.55 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A ING2 | negative regulation of multicellular organismal process |
| GO:0051252 | 5.07178504008e-06 | 0.85 | BRMS1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B ING1 TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | regulation of RNA metabolic process |
| GO:0071495 | 5.83072603419e-06 | 0.6 | BRMS1 ING1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 PDGFRB SAP30 SIN3A ING2 | cellular response to endogenous stimulus |
| GO:0009968 | 8.8305352113e-06 | 0.6 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A TERT ING2 | negative regulation of signal transduction |
| GO:0010648 | 1.28442176771e-05 | 0.6 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A TERT ING2 | negative regulation of cell communication |
| GO:0023057 | 1.3857820887e-05 | 0.6 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A TERT ING2 | negative regulation of signaling |
| GO:0009719 | 1.57098948298e-05 | 0.6 | BRMS1 ING1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 PDGFRB SAP30 SIN3A ING2 | response to endogenous stimulus |
| REAC:R-HSA-3214815 | 1.95475306984e-05 | 0.25 | BRMS1 SAP30L SUDS3 ARID4B SAP30 | HDACs deacetylate histones |
| GO:0044271 | 2.07227098309e-05 | 0.9 | BRMS1 ING1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B PDGFRB TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | cellular nitrogen compound biosynthetic process |
| GO:0051240 | 2.29727058986e-05 | 0.6 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A TERT ING2 | positive regulation of multicellular organismal process |
| REAC:R-HSA-9679191 | 2.65575220522e-05 | 0.25 | BRMS1 SAP30L SUDS3 ARID4B SAP30 | Potential therapeutics for SARS |
| GO:0010556 | 3.13222540504e-05 | 0.9 | BRMS1 ING1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B PDGFRB TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | regulation of macromolecule biosynthetic process |
| GO:0051094 | 3.93120850451e-05 | 0.55 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A ING2 | positive regulation of developmental process |
| GO:0031326 | 4.59603680056e-05 | 0.9 | BRMS1 ING1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B PDGFRB TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | regulation of cellular biosynthetic process |
| GO:0009889 | 5.09499988281e-05 | 0.9 | BRMS1 ING1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B PDGFRB TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | regulation of biosynthetic process |
| CORUM:697 | 6.49329465809e-05 | 0.1 | BRMS1 ARID4B | BRMS1-RBP1 complex |
| GO:0090304 | 7.94393940946e-05 | 0.9 | BRMS1 ING1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B PDGFRB TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | nucleic acid metabolic process |
| GO:0048585 | 0.00011736550694 | 0.6 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A TERT ING2 | negative regulation of response to stimulus |
| GO:0051171 | 0.000195257315744 | 0.9 | BRMS1 ING1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B PDGFRB TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | regulation of nitrogen compound metabolic process |
| GO:0016070 | 0.000201384750081 | 0.85 | BRMS1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B ING1 TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | RNA metabolic process |
| REAC:R-HSA-4839726 | 0.000232294614434 | 0.3 | BRMS1 SAP30L SUDS3 ARID4B SAP30 SAP130 | Chromatin organization |
| REAC:R-HSA-3247509 | 0.000232294614434 | 0.3 | BRMS1 SAP30L SUDS3 ARID4B SAP30 SAP130 | Chromatin modifying enzymes |
| GO:0080090 | 0.000299424959413 | 0.9 | BRMS1 ING1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B PDGFRB TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | regulation of primary metabolic process |
| GO:0010468 | 0.00037442088189 | 0.85 | BRMS1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B ING1 TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | regulation of gene expression |
| CORUM:745 | 0.00038895809385 | 0.1 | SIN3A SIN3B | NCOR-SIN3-RPD3 complex |
| CORUM:6443 | 0.00038895809385 | 0.1 | SIN3A SIN3B | SMAR1-HDAC1-SIN3A-SIN3B repressor complex |
| GO:0048523 | 0.000392891526674 | 0.85 | BRMS1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B ING1 TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | negative regulation of cellular process |
| GO:0006139 | 0.000494758878678 | 0.9 | BRMS1 ING1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B PDGFRB TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | nucleobase-containing compound metabolic process |
| CORUM:3167 | 0.000647731199222 | 0.1 | SIN3A SIN3B | NCOR-SIN3-HDAC-HESX1 complex |
| GO:0046483 | 0.00081882953627 | 0.9 | BRMS1 ING1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B PDGFRB TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | heterocycle metabolic process |
| GO:0006725 | 0.00086396546884 | 0.9 | BRMS1 ING1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B PDGFRB TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | cellular aromatic compound metabolic process |
| GO:0032993 | 0.000949427112337 | 0.55 | BRMS1 FOXK1 SAP130 BRMS1L TGIF2LX SIN3B FOXK2 SIN3A TGIF2 SUDS3 TERT | protein-DNA complex |
| CORUM:6444 | 0.000970799059727 | 0.1 | SIN3A SIN3B | SMAR1-HDAC1-SIN3A-SIN3B-p107-p130 repressor complex |
| GO:0060255 | 0.00102209483492 | 0.9 | BRMS1 ING1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B PDGFRB TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | regulation of macromolecule metabolic process |
| GO:0031323 | 0.00106458665311 | 0.9 | BRMS1 ING1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B PDGFRB TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | regulation of cellular metabolic process |
| GO:0048519 | 0.00124893309637 | 0.85 | BRMS1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B ING1 TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | negative regulation of biological process |
| GO:0007166 | 0.00133765354275 | 0.65 | BRMS1 ING1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 PDGFRB SAP30 SIN3A TERT ING2 | cell surface receptor signaling pathway |
| CORUM:1505 | 0.00135800282338 | 0.1 | SAP30 SIN3A | NCOR2 complex |
| CORUM:732 | 0.00135800282338 | 0.1 | SAP30 SIN3A | SIN3 complex |
| CORUM:283 | 0.00135800282338 | 0.1 | SAP30 SIN3A | Sin3 complex |
| CORUM:54 | 0.00135800282338 | 0.1 | SAP30 SIN3A | SIN3 complex |
| GO:1901360 | 0.00161008906626 | 0.9 | BRMS1 ING1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B PDGFRB TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | organic cyclic compound metabolic process |
| HP:0032059 | 0.00211805087657 | 0.1 | SIN3A SIN3B | Mild malformation of cortical development |
| GO:0034641 | 0.00342693280519 | 0.9 | BRMS1 ING1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B PDGFRB TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | cellular nitrogen compound metabolic process |
| GO:0019222 | 0.00442361584295 | 0.9 | BRMS1 ING1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B PDGFRB TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | regulation of metabolic process |
| REAC:R-HSA-74160 | 0.0070195808135 | 0.45 | SAP130 ING2 SAP30L ARID4B SIN3B SUDS3 SIN3A SAP30 TGIF2 | Gene expression (Transcription) |
| GO:0009059 | 0.00705062151798 | 0.9 | BRMS1 ING1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B PDGFRB TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | macromolecule biosynthetic process |
| GO:0000785 | 0.00808800356939 | 0.5 | BRMS1 FOXK1 SAP130 BRMS1L TGIF2LX SIN3B FOXK2 SIN3A TGIF2 SUDS3 | chromatin |
| GO:0009966 | 0.0119256262103 | 0.65 | BRMS1 ING1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 PDGFRB SAP30 SIN3A TERT ING2 | regulation of signal transduction |
| GO:0005694 | 0.0217882819133 | 0.55 | BRMS1 FOXK1 SAP130 BRMS1L TGIF2LX SIN3B FOXK2 SIN3A TGIF2 SUDS3 TERT | chromosome |
| CORUM:1257 | 0.0240262805484 | 0.1 | SAP30 SIN3A | ALL-1 supercomplex |
| GO:0010467 | 0.0249981879236 | 0.85 | BRMS1 ING2 SAP130 BRMS1L SAP30L TGIF2LX SIN3B FOXK2 ARID4B ING1 TGIF2 SAP30 SUDS3 SIN3A TERT FOXK1 SINHCAF | gene expression |
| GO:0051239 | 0.0275020414827 | 0.6 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A TERT ING2 | regulation of multicellular organismal process |
| GO:0050793 | 0.028421721774 | 0.55 | BRMS1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 ING1 SAP30 SIN3A ING2 | regulation of developmental process |
| WP:WP4533 | 0.0331677310052 | 0.1 | ING2 SIN3A | Transcription co factors SKI and SKIL protein partners |
| GO:0023051 | 0.0361235938215 | 0.65 | BRMS1 ING1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 PDGFRB SAP30 SIN3A TERT ING2 | regulation of signaling |
| GO:0010646 | 0.0366981925939 | 0.65 | BRMS1 ING1 SINHCAF SAP130 BRMS1L SAP30L ARID4B SUDS3 PDGFRB SAP30 SIN3A TERT ING2 | regulation of cell communication |
| REAC:R-HSA-9679506 | 0.038411740124 | 0.25 | BRMS1 SAP30L SUDS3 ARID4B SAP30 | SARS-CoV Infections |
| CORUM:1163 | 0.0499436884912 | 0.05 | ING1 | ING1-PCNA complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD |
|---|---|---|---|
| SAP30 | ARID4B | 1.0 | 0.196 |
| SAP30 | SAP130 | 1.0 | |
| SAP30 | SINHCAF | 1.0 | 0.16 |
| SINHCAF | SUDS3 | 1.0 | 0.168 |
| BRMS1L | SINHCAF | 1.0 | 0.098 |
| BAHCC1 | SINHCAF | 1.0 | |
| BRMS1 | SINHCAF | 1.0 | 0.198 |
| SAP30 | BRMS1 | 1.0 | 0.3 |
| SAP30 | SUDS3 | 1.0 | 0.22 |
| SAP30 | BRMS1L | 1.0 | 0.134 |
| ING1 | SAP130 | 1.0 | |
| SAP30 | ARID4A | 1.0 | 0.144 |
| SAP30 | ING1 | 1.0 | 0.216 |
| ING1 | SINHCAF | 1.0 | 0.086 |
| SAP30 | ING2 | 1.0 | 0.112 |
| SIN3A | ARID4B | 1.0 | 0.322 |
| SAP130 | ING2 | 1.0 | |
| BRMS1L | ING2 | 1.0 | 0.176 |
| BRMS1 | SIN3A | 1.0 | 0.358 |
| SIN3A | ARID4A | 1.0 | 0.26 |
| SAP130 | SINHCAF | 1.0 | |
| SAP30 | BAHCC1 | 1.0 | |
| BAHCC1 | ING2 | 1.0 | |
| ING2 | SINHCAF | 1.0 | 0.12 |
| ING1 | BRMS1L | 1.0 | 0.296 |
| BRMS1 | ING2 | 1.0 | 0.13 |
| ING2 | SUDS3 | 1.0 | 0.146 |
| SAP30 | SIN3A | 1.0 | 0.562 |
| SAP30 | FOXK1 | 1.0 | 0.12 |
| ARID4A | SINHCAF | 1.0 | 0.072 |
| ING1 | BAHCC1 | 1.0 | |
| SIN3B | SINHCAF | 1.0 | 0.172 |
| ING1 | ARID4A | 1.0 | 0.128 |
| SIN3A | SAP130 | 0.999 | |
| SAP30L | SINHCAF | 0.999 | 0.09 |
| BRMS1 | ARID4B | 0.999 | 0.216 |
| ING1 | SUDS3 | 0.999 | 0.256 |
| SIN3A | SINHCAF | 0.999 | 0.256 |
| SAP130 | ARID4B | 0.999 | |
| ING1 | ARID4B | 0.999 | 0.152 |
| BRMS1 | ARID4A | 0.999 | 0.128 |
| SIN3B | BRMS1L | 0.999 | 0.238 |
| ING1 | SIN3A | 0.999 | 0.216 |
| ING1 | BRMS1 | 0.999 | 0.112 |
| ING2 | ARID4B | 0.999 | 0.124 |
| SIN3B | SAP30 | 0.999 | 0.236 |
| ARID4A | ING2 | 0.999 | 0.168 |
| BAHCC1 | SAP130 | 0.999 | |
| BAHCC1 | BRMS1L | 0.999 | |
| BRMS1 | BAHCC1 | 0.999 | |
| BAHCC1 | ARID4B | 0.999 | |
| ARID4A | BAHCC1 | 0.999 | |
| BRMS1 | BRMS1L | 0.999 | 0.076 |
| SIN3B | BRMS1 | 0.999 | 0.126 |
| BAHCC1 | SUDS3 | 0.999 | |
| ARID4A | ARID4B | 0.999 | 0.126 |
| BRMS1L | SAP130 | 0.999 | |
| BRMS1 | SAP130 | 0.999 | |
| SAP30 | TNRC18 | 0.999 | 0.102 |
| SIN3B | ING2 | 0.999 | 0.192 |
| SIN3A | BRMS1L | 0.999 | 0.25 |
| ARID4B | SUDS3 | 0.999 | 0.196 |
| ARID4B | SINHCAF | 0.999 | 0.072 |
| SIN3A | SUDS3 | 0.999 | 0.33 |
| SAP30L | ING2 | 0.999 | 0.11 |
| ING1 | TNRC18 | 0.999 | 0.076 |
| BRMS1 | SUDS3 | 0.999 | 0.176 |
| SIN3B | ARID4B | 0.999 | 0.192 |
| SIN3A | ING2 | 0.999 | 0.16 |
| BRMS1L | ARID4B | 0.999 | 0.106 |
| BRMS1L | SUDS3 | 0.999 | 0.214 |
| ARID4A | SUDS3 | 0.999 | 0.284 |
| SIN3B | ING1 | 0.999 | 0.208 |
| SIN3B | BAHCC1 | 0.999 | |
| SAP130 | SUDS3 | 0.999 | |
| SAP30 | TGIF2LX | 0.999 | |
| ING1 | FOXK1 | 0.999 | 0.072 |
| BRMS1 | TGIF2LX | 0.999 | |
| SUDS3 | FOXK1 | 0.999 | 0.12 |
| BRMS1L | TGIF2LX | 0.999 | |
| ING2 | FOXK1 | 0.998 | 0.074 |
| TNRC18 | SINHCAF | 0.998 | 0.078 |
| SIN3A | BAHCC1 | 0.998 | |
| SIN3B | SUDS3 | 0.998 | 0.254 |
| ARID4A | SAP130 | 0.998 | |
| SAP130 | FOXK1 | 0.998 | |
| ING1 | TGIF2LX | 0.998 | |
| SIN3B | ARID4A | 0.998 | 0.222 |
| SAP30 | SAP30L | 0.998 | 0.174 |
| ING1 | SAP30L | 0.998 | 0.232 |
| ARID4B | FOXK1 | 0.998 | 0.072 |
| ARID4A | FOXK1 | 0.998 | 0.074 |
| TGIF2LX | SUDS3 | 0.997 | |
| SINHCAF | FOXK1 | 0.997 | 0.066 |
| SIN3A | TNRC18 | 0.997 | 0.106 |
| BAHCC1 | FOXK1 | 0.997 | |
| SIN3B | SIN3A | 0.997 | 0.352 |
| ARID4A | BRMS1L | 0.997 | 0.206 |
| SAP30 | FOXK2 | 0.997 | 0.138 |
| BRMS1 | FOXK1 | 0.997 | 0.094 |
| FOXK2 | FOXK1 | 0.996 | 0.242 |
| SIN3B | SAP130 | 0.996 | |
| BRMS1L | FOXK1 | 0.996 | 0.062 |
| ARID4A | SAP30L | 0.996 | 0.218 |
| SIN3B | FOXK1 | 0.996 | 0.138 |
| SIN3B | SAP30L | 0.995 | 0.2 |
| TGIF2LX | SINHCAF | 0.995 | |
| ARID4A | TGIF2LX | 0.995 | |
| BRMS1 | SAP30L | 0.995 | 0.122 |
| TGIF2LX | ING2 | 0.995 | |
| SAP30L | TGIF2LX | 0.995 | |
| SIN3A | SAP30L | 0.995 | 0.184 |
| FOXK2 | ING2 | 0.995 | 0.158 |
| SIN3B | TNRC18 | 0.995 | 0.066 |
| FOXK2 | SUDS3 | 0.993 | 0.22 |
| SAP30L | BAHCC1 | 0.993 | |
| SAP130 | TGIF2LX | 0.992 | |
| ING2 | TNRC18 | 0.991 | 0.064 |
| FOXK2 | SINHCAF | 0.991 | 0.118 |
| SAP30L | SAP130 | 0.99 | |
| SAP30L | SUDS3 | 0.99 | 0.198 |
| SAP30L | ARID4B | 0.99 | 0.172 |
| SIN3A | FOXK1 | 0.99 | 0.158 |
| SIN3B | TGIF2LX | 0.99 | |
| SAP130 | TNRC18 | 0.99 | |
| SAP30L | BRMS1L | 0.989 | 0.206 |
| ING1 | ING2 | 0.989 | 0.104 |
| FOXK2 | ARID4A | 0.987 | 0.076 |
| FOXK2 | BRMS1L | 0.986 | 0.11 |
| FOXK2 | ING1 | 0.986 | 0.194 |
| SIN3A | TGIF2LX | 0.985 | |
| FOXK2 | BRMS1 | 0.985 | 0.166 |
| FOXK2 | ARID4B | 0.985 | 0.15 |
| TERT | SUDS3 | 0.984 | |
| SAP30 | TGIF2 | 0.983 | |
| SIN3B | FOXK2 | 0.982 | 0.174 |
| FOXK2 | BAHCC1 | 0.982 | |
| TGIF2LX | ARID4B | 0.981 | |
| FOXK1 | PDGFRB | 0.98 | 0.02 |
| BAHCC1 | TNRC18 | 0.979 | |
| BAHCC1 | TGIF2LX | 0.979 | |
| FOXK2 | SIN3A | 0.973 | 0.26 |
| FOXK2 | SAP130 | 0.972 | |
| BRMS1 | TNRC18 | 0.97 | 0.11 |
| ARID4B | TNRC18 | 0.969 | 0.116 |
| ARID4A | TNRC18 | 0.968 | 0.148 |
| TGIF2 | SAP130 | 0.957 | |
| TGIF2LX | TNRC18 | 0.951 | |
| TGIF2 | SAP30L | 0.935 | |
| BRMS1L | TNRC18 | 0.928 | 0.06 |
| FOXK2 | SAP30L | 0.926 | 0.098 |
| TNRC18 | SUDS3 | 0.916 | 0.194 |
| TGIF2 | SIN3A | 0.912 | |
| SAP30L | FOXK1 | 0.91 | 0.066 |
| TGIF2 | SUDS3 | 0.908 | |
| BRMS1 | TGIF2 | 0.899 | |
| TGIF2 | ARID4A | 0.889 | |
| TGIF2 | ING2 | 0.84 | |
| SAP30L | TNRC18 | 0.839 | 0.112 |
| TGIF2 | BRMS1L | 0.839 | |
| TNRC18 | FOXK1 | 0.83 | 0.046 |
| TGIF2 | ARID4B | 0.745 | |
| FOXK2 | TNRC18 | 0.734 | 0.054 |
| FOXK2 | PDGFRB | 0.66 | 0.026 |
| SIN3A | TERT | 0.164 | |
| SIN3B | TERT | 0.164 | |
| FOXK2 | TGIF2LX | 0.079 | |
| TGIF2LX | FOXK1 | 0.051 |
Related Complexes