hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09312.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SFPQ | Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor) | 5 | UniProt NCBI |
| EWSR1 | RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein) | 5 | UniProt NCBI |
| PSPC1 | Paraspeckle component 1 (Paraspeckle protein 1) | 5 | UniProt NCBI |
| NONO | Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7285 | 5.12534978153e-05 | 0.666666666667 | NONO PSPC1 | HEXIM1-DNA-PK-paraspeckle components-ribonucleoprotein complex |
| HPA:0050013 | 0.000494843580229 | 1.0 | NONO EWSR1 PSPC1 | breast; adipocytes[High] |
| HPA:0301363 | 0.0023056152729 | 1.0 | NONO EWSR1 PSPC1 | lung; alveolar cells type I[High] |
| HPA:0460643 | 0.00292708231121 | 1.0 | NONO EWSR1 PSPC1 | skin 1; Langerhans[High] |
| HPA:0301373 | 0.00533567167257 | 1.0 | NONO EWSR1 PSPC1 | lung; alveolar cells type II[High] |
| HPA:0570771 | 0.00554387032948 | 1.0 | NONO EWSR1 PSPC1 | testis; peritubular cells[>=Low] |
| HPA:0570783 | 0.0059487071562 | 1.0 | NONO EWSR1 PSPC1 | testis; preleptotene spermatocytes[High] |
| HPA:0300201 | 0.00927194305323 | 1.0 | NONO EWSR1 PSPC1 | lung; endothelial cells[>=Low] |
| HPA:0050093 | 0.0103511455105 | 1.0 | NONO EWSR1 PSPC1 | breast; myoepithelial cells[High] |
| HPA:0130243 | 0.0103511455105 | 1.0 | NONO EWSR1 PSPC1 | colon; peripheral nerve/ganglion[High] |
| HPA:0090193 | 0.0123005616242 | 1.0 | NONO EWSR1 PSPC1 | cerebellum; cells in molecular layer[High] |
| HPA:0301362 | 0.0123904558405 | 1.0 | NONO EWSR1 PSPC1 | lung; alveolar cells type I[>=Medium] |
| WP:WP3594 | 0.0141264814409 | 0.666666666667 | NONO PSPC1 | Circadian rhythm genes |
| HPA:0460673 | 0.0169594584426 | 1.0 | NONO EWSR1 PSPC1 | skin 1; melanocytes[High] |
| HPA:0301361 | 0.0228023243263 | 1.0 | NONO EWSR1 PSPC1 | lung; alveolar cells type I[>=Low] |
| CORUM:330 | 0.0249718442456 | 0.333333333333 | NONO | PSF-p54(nrb) complex |
| CORUM:1760 | 0.0249718442456 | 0.333333333333 | NONO | TOP1-PSF-P54 complex |
| HPA:0380513 | 0.030835510288 | 1.0 | NONO EWSR1 PSPC1 | placenta; decidual cells[High] |
| HPA:0301372 | 0.0337351920324 | 1.0 | NONO EWSR1 PSPC1 | lung; alveolar cells type II[>=Medium] |
| HPA:0570773 | 0.035534021141 | 0.666666666667 | NONO EWSR1 | testis; peritubular cells[High] |
| HPA:0170053 | 0.0406627923068 | 1.0 | NONO EWSR1 PSPC1 | endometrium 2; glandular cells[High] |
| HPA:0050053 | 0.0436171192214 | 1.0 | NONO EWSR1 PSPC1 | breast; glandular cells[High] |
| HPA:0570782 | 0.0440355061936 | 1.0 | NONO EWSR1 PSPC1 | testis; preleptotene spermatocytes[>=Medium] |
| HPA:0570813 | 0.0443510461782 | 1.0 | NONO EWSR1 PSPC1 | testis; spermatogonia cells[High] |
| CORUM:335 | 0.0499402709677 | 0.333333333333 | NONO | p54(nrb)-PSF-matrin3 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NONO | SFPQ | 1.0 | 0.992 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt Malo bioplex3_HCT116 fraction boldt_WMM treiber_WMM |
| PSPC1 | NONO | 1.0 | 0.62 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 fraction boldt_WMM treiber_WMM |
| PSPC1 | SFPQ | 0.999 | 0.674 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 fraction boldt_WMM treiber_WMM |
| SFPQ | EWSR1 | 0.963 | 0.632 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction treiber_WMM |
| NONO | EWSR1 | 0.54 | 0.446 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt fraction boldt_WMM treiber_WMM |
| PSPC1 | EWSR1 | 0.123 | 0.434 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
Related Complexes