hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09314.1
Complex Portal: CPX-21574
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LURAP1L | Leucine rich adaptor protein 1-like | 3 | UniProt NCBI |
| CDC42BPA | Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha) | 5 | UniProt NCBI |
| TSGA10 | Testis-specific gene 10 protein (Testis development protein NYD-SP7) | 5 | UniProt NCBI |
| ARHGAP35 | Rho GTPase-activating protein 35 (Glucocorticoid receptor DNA-binding factor 1) (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A) | 5 | UniProt NCBI |
| SHTN1 | Shootin-1 (Shootin1) | 5 | UniProt NCBI |
| CDC42BPG | Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) (DMPK-like gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (MRCK gamma) (MRCKG) (Myotonic dystrophy protein kinase-like gamma) (Myotonic dystrophy protein kinase-like alpha) | 5 | UniProt NCBI |
| NYNRIN | Protein NYNRIN (NYN domain and retroviral integrase catalytic domain-containing protein) (Protein cousin of GIN1) | 4 | UniProt NCBI |
| ARHGAP4 | Rho GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (Rho-type GTPase-activating protein 4) (p115) | 5 | UniProt NCBI |
| FAM167A | Protein FAM167A | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9013148 | 0.0119915115759 | 0.333333333333 | ARHGAP4 CDC42BPA ARHGAP35 | CDC42 GTPase cycle |
| REAC:R-HSA-9013149 | 0.0235262214575 | 0.333333333333 | ARHGAP4 CDC42BPA ARHGAP35 | RAC1 GTPase cycle |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CDC42BPA | FAM167A | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| LURAP1L | CDC42BPA | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| FAM167A | CDC42BPG | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| ARHGAP4 | FAM167A | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TSGA10 | FAM167A | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| NYNRIN | FAM167A | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ARHGAP35 | FAM167A | 0.991 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| LURAP1L | CDC42BPG | 0.991 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| FAM167A | SHTN1 | 0.989 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| LURAP1L | SHTN1 | 0.98 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| CDC42BPA | CDC42BPG | 0.871 | 0.052 | bioplex_WMM bioplex3_WMM WMM_only | |
| SHTN1 | CDC42BPG | 0.467 | 0.064 | bioplex_WMM bioplex3_WMM WMM_only | |
| CDC42BPA | ARHGAP4 | 0.356 | 0.154 | bioplex3_WMM WMM_only | |
| NYNRIN | TSGA10 | 0.333 | bioplex_WMM bioplex3_WMM WMM_only | ||
| CDC42BPA | SHTN1 | 0.291 | 0.072 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ARHGAP35 | ARHGAP4 | 0.188 | 0.114 | bioplex3_WMM WMM_only | |
| TSGA10 | SHTN1 | 0.188 | bioplex_WMM bioplex3_WMM WMM_only | ||
| NYNRIN | CDC42BPG | 0.188 | 0.08 | bioplex_WMM bioplex3_WMM WMM_only | |
| CDC42BPA | TSGA10 | 0.172 | bioplex_WMM bioplex3_WMM WMM_only | ||
| TSGA10 | CDC42BPG | 0.164 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ARHGAP4 | CDC42BPG | 0.153 | 0.16 | bioplex3_WMM WMM_only | |
| ARHGAP35 | CDC42BPG | 0.15 | 0.118 | bioplex3_WMM WMM_only | |
| ARHGAP4 | TSGA10 | 0.146 | bioplex3_WMM WMM_only | ||
| NYNRIN | CDC42BPA | 0.124 | 0.07 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| CDC42BPA | ARHGAP35 | 0.109 | 0.08 | bioplex3_WMM youn_WMM WMM_only | |
| NYNRIN | SHTN1 | 0.095 | 0.108 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ARHGAP4 | SHTN1 | 0.074 | 0.162 | bioplex3_WMM WMM_only | |
| ARHGAP35 | TSGA10 | 0.046 | bioplex3_WMM WMM_only | ||
| NYNRIN | ARHGAP4 | 0.043 | 0.228 | bioplex3_WMM WMM_only | |
| ARHGAP35 | SHTN1 | 0.027 | 0.084 | bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| NYNRIN | ARHGAP35 | 0.018 | 0.088 | bioplex3_WMM youn_WMM WMM_only |
Related Complexes