hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09323.1
Complex Portal: CPX-22057
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| AARS1 | Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS) (Renal carcinoma antigen NY-REN-42) | 5 | UniProt NCBI |
| IDH2 | Isocitrate dehydrogenase [NADP], mitochondrial (IDH) (EC 1.1.1.42) (ICD-M) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase) | 5 | UniProt NCBI |
| TCEA1 | Transcription elongation factor A protein 1 (Transcription elongation factor S-II protein 1) (Transcription elongation factor TFIIS.o) | 5 | UniProt NCBI |
| VRK1 | Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6948 | 0.0249718442456 | 0.25 | IDH2 | Isocitrate dehydrogenase [NADP], mitochondrial |
| CORUM:7101 | 0.049938562206 | 0.25 | VRK1 | AURKB-VRK1 complex |
| CORUM:7102 | 0.049938562206 | 0.25 | VRK1 | SOX2-VRK1 complex |
| CORUM:7103 | 0.049938562206 | 0.25 | VRK1 | NBS1-VRK1 complex |
| CORUM:7104 | 0.049938562206 | 0.25 | VRK1 | NBS1-RNF8-VRK1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TCEA1 | VRK1 | 0.992 | 0.108 | bioplex_WMM bioplex3_WMM fraction | |
| VRK1 | IDH2 | 0.97 | 0.056 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| AARS1 | IDH2 | 0.953 | 0.262 | bioplex_WMM bioplex3_WMM boldt gupta_WMM fraction boldt_WMM | |
| AARS1 | VRK1 | 0.659 | 0.182 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| TCEA1 | AARS1 | 0.284 | 0.152 | bioplex_WMM bioplex3_WMM fraction | |
| TCEA1 | IDH2 | 0.043 | 0.146 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM |
Related Complexes