hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09345.1
Complex Portal: CPX-15872
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GPSM2 | G-protein-signaling modulator 2 (Mosaic protein LGN) | 5 | UniProt NCBI |
| INSC | Protein inscuteable homolog | 5 | UniProt NCBI |
| SCNM1 | Sodium channel modifier 1 | 5 | UniProt NCBI |
| SBNO2 | Protein strawberry notch homolog 2 | 5 | UniProt NCBI |
| USP11 | Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.4.19.12) (Deubiquitinating enzyme 11) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) | 5 | UniProt NCBI |
| KDM3A | Lysine-specific demethylase 3A (EC 1.14.11.65) (JmjC domain-containing histone demethylation protein 2A) (Jumonji domain-containing protein 1A) ([histone H3]-dimethyl-L-lysine(9) demethylase 3A) | 5 | UniProt NCBI |
| CHEK1 | Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1) | 5 | UniProt NCBI |
| TDP2 | Tyrosyl-DNA phosphodiesterase 2 (Tyr-DNA phosphodiesterase 2) (hTDP2) (EC 3.1.4.-) (5'-tyrosyl-DNA phosphodiesterase) (5'-Tyr-DNA phosphodiesterase) (ETS1-associated protein 2) (ETS1-associated protein II) (EAPII) (TRAF and TNF receptor-associated protein) (Tyrosyl-RNA phosphodiesterase) (VPg unlinkase) | 5 | UniProt NCBI |
| TCEAL1 | Transcription elongation factor A protein-like 1 (TCEA-like protein 1) (Nuclear phosphoprotein p21/SIIR) (Transcription elongation factor S-II protein-like 1) | 5 | UniProt NCBI |
| ZUP1 | Zinc finger-containing ubiquitin peptidase 1 (EC 3.4.19.12) (Lys-63-specific deubiquitinase ZUFSP) (DUB) (Zinc finger with UFM1-specific peptidase domain protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7559 | 9.22394575203e-05 | 0.2 | GPSM2 INSC | INSC-LGN-PAR3 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TCEAL1 | ZUP1 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| USP11 | TCEAL1 | 0.998 | 0.126 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 | |
| GPSM2 | TCEAL1 | 0.997 | 0.1 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TDP2 | TCEAL1 | 0.997 | 0.074 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| CHEK1 | TCEAL1 | 0.995 | 0.182 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| SCNM1 | TCEAL1 | 0.992 | 0.094 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| SBNO2 | TCEAL1 | 0.992 | 0.036 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| INSC | GPSM2 | 0.987 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| KDM3A | TCEAL1 | 0.981 | 0.036 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| SCNM1 | ZUP1 | 0.967 | bioplex_WMM bioplex3_WMM WMM_only | ||
| GPSM2 | SCNM1 | 0.967 | 0.124 | bioplex_WMM bioplex3_WMM WMM_only | |
| GPSM2 | KDM3A | 0.959 | 0.094 | bioplex_WMM bioplex3_WMM WMM_only | |
| KDM3A | ZUP1 | 0.959 | bioplex_WMM bioplex3_WMM WMM_only | ||
| GPSM2 | ZUP1 | 0.956 | bioplex_WMM bioplex3_WMM WMM_only | ||
| TDP2 | SCNM1 | 0.947 | 0.096 | bioplex_WMM bioplex3_WMM WMM_only | |
| CHEK1 | ZUP1 | 0.938 | bioplex_WMM bioplex3_WMM WMM_only | ||
| GPSM2 | CHEK1 | 0.938 | 0.1324 | bioplex_WMM bioplex3_WMM WMM_only | |
| TDP2 | KDM3A | 0.933 | 0.04 | bioplex_WMM bioplex3_WMM WMM_only | |
| KDM3A | SCNM1 | 0.932 | 0.082 | bioplex_WMM bioplex3_WMM WMM_only | |
| TDP2 | ZUP1 | 0.928 | bioplex_WMM bioplex3_WMM WMM_only | ||
| GPSM2 | TDP2 | 0.928 | 0.102 | bioplex_WMM bioplex3_WMM WMM_only | |
| TDP2 | CHEK1 | 0.919 | 0.212 | bioplex_WMM bioplex3_WMM WMM_only | |
| SBNO2 | ZUP1 | 0.902 | bioplex3_WMM WMM_only | ||
| GPSM2 | SBNO2 | 0.902 | 0.078 | bioplex3_WMM WMM_only | |
| SCNM1 | SBNO2 | 0.902 | 0.12 | bioplex3_WMM WMM_only | |
| TDP2 | SBNO2 | 0.869 | 0.108 | bioplex3_WMM WMM_only | |
| USP11 | SCNM1 | 0.824 | 0.082 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| KDM3A | CHEK1 | 0.807 | 0.082 | bioplex_WMM bioplex3_WMM WMM_only | |
| CHEK1 | SBNO2 | 0.675 | 0.152 | bioplex3_WMM WMM_only | |
| KDM3A | SBNO2 | 0.661 | 0.084 | bioplex3_WMM youn_WMM WMM_only | |
| GPSM2 | USP11 | 0.642 | 0.114 | bioplex_WMM bioplex3_WMM WMM_only | |
| CHEK1 | SCNM1 | 0.591 | 0.232 | bioplex_WMM bioplex3_WMM WMM_only | |
| USP11 | ZUP1 | 0.568 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | ||
| TDP2 | USP11 | 0.224 | 0.062 | bioplex_WMM bioplex3_WMM WMM_only | |
| KDM3A | USP11 | 0.223 | 0.094 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| USP11 | SBNO2 | 0.207 | 0.052 | bioplex3_WMM youn_WMM WMM_only | |
| USP11 | CHEK1 | 0.054 | 0.122 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| INSC | USP11 | 0.016 | bioplex3_HEK293 WMM_only |
Related Complexes