hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_09348.1

Complex Portal: CPX-14932

Confidence: Moderate High

Genename	Protein Name	Uniprot Annotation Score	Links
MYL6B	Myosin light chain 6B (Myosin light chain 1 slow-twitch muscle A isoform) (MLC1sa) (Smooth muscle and nonmuscle myosin light chain alkali 6B)	5	UniProt NCBI
MYO1C	Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb)	5	UniProt NCBI
PALM2AKAP2	PALM2 and AKAP2 fusion	1	UniProt NCBI
MYO5B	Unconventional myosin-Vb	5	UniProt NCBI
MTFR1	Mitochondrial fission regulator 1 (Chondrocyte protein with a poly-proline region)	4	UniProt NCBI
KCTD10	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 (hBACURD3) (BTB/POZ domain-containing protein KCTD10) (Potassium channel tetramerization domain-containing protein 10)	5	UniProt NCBI
TNFAIP1	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (hBACURD2) (BTB/POZ domain-containing protein TNFAIP1) (Protein B12) (Tumor necrosis factor, alpha-induced protein 1, endothelial)	5	UniProt NCBI
MYO5C	Unconventional myosin-Vc	5	UniProt NCBI
CAMK2G	Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)	5	UniProt NCBI
DAPK3	Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)	5	UniProt NCBI
CAPZA2	F-actin-capping protein subunit alpha-2 (CapZ alpha-2)	5	UniProt NCBI
MYO5A	Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myosin-12) (Myoxin)	5	UniProt NCBI
MYO1E	Unconventional myosin-Ie (Myosin-Ic) (Unconventional myosin 1E)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0030050	2.13304555418e-08	0.416666666667	MYO1C MYO5A MYO1E MYO5B MYO5C	vesicle transport along actin filament
GO:0099515	4.39185568067e-08	0.416666666667	MYO1C MYO5A MYO1E MYO5B MYO5C	actin filament-based transport
KEGG:04814	7.68391335435e-08	0.5	MYO5B MYO5C MYO5A MYO1E CAPZA2 MYO1C	Motor proteins
GO:0000146	1.42069743999e-06	0.416666666667	MYO1C MYO5A MYO1E MYO5B MYO5C	microfilament motor activity
KEGG:05130	6.66538536998e-06	0.416666666667	MYO1C MYO5A MYO1E MYO5B MYO5C	Pathogenic Escherichia coli infection
GO:0099518	4.8976844024e-05	0.416666666667	MYO1C MYO5A MYO1E MYO5B MYO5C	vesicle cytoskeletal trafficking
GO:0030036	6.27489836348e-05	0.666666666667	DAPK3 MYO5C TNFAIP1 MYO5A MYO1E CAPZA2 MYO1C MYO5B	actin cytoskeleton organization
GO:0051015	9.54139187613e-05	0.5	MYO5B MYO5C MYO5A MYO1E CAPZA2 MYO1C	actin filament binding
GO:0007015	0.00011683385645	0.583333333333	MYO5B MYO5C TNFAIP1 MYO5A MYO1E CAPZA2 MYO1C	actin filament organization
GO:0030029	0.000148299709923	0.666666666667	DAPK3 MYO5C TNFAIP1 MYO5A MYO1E CAPZA2 MYO1C MYO5B	actin filament-based process
GO:0003774	0.000286226865954	0.416666666667	MYO1C MYO5A MYO1E MYO5B MYO5C	cytoskeletal motor activity
GO:0030048	0.00032042667326	0.416666666667	MYO1C MYO5A MYO1E MYO5B MYO5C	actin filament-based movement
GO:0003779	0.00180470969369	0.5	MYO5B MYO5C MYO5A MYO1E CAPZA2 MYO1C	actin binding
GO:0097435	0.00664911968421	0.583333333333	MYO5B MYO5C TNFAIP1 MYO5A MYO1E CAPZA2 MYO1C	supramolecular fiber organization
GO:0051650	0.00701586783564	0.416666666667	MYO1C MYO5A MYO1E MYO5B MYO5C	establishment of vesicle localization
GO:0030705	0.00812179610849	0.416666666667	MYO1C MYO5A MYO1E MYO5B MYO5C	cytoskeleton-dependent intracellular transport
GO:0051648	0.00835872057838	0.416666666667	MYO1C MYO5A MYO1E MYO5B MYO5C	vesicle localization
GO:0031267	0.00962706215244	0.416666666667	DAPK3 MYO1C MYO5A MYO5B TNFAIP1	small GTPase binding
GO:0015629	0.0112948093171	0.5	MYO5B MYO5C MYO5A MYO1E CAPZA2 MYO1C	actin cytoskeleton
GO:0051020	0.0189049260749	0.416666666667	DAPK3 MYO1C MYO5A MYO5B TNFAIP1	GTPase binding
GO:0007010	0.0191816160898	0.666666666667	DAPK3 MYO5C TNFAIP1 MYO5A MYO1E CAPZA2 MYO1C MYO5B	cytoskeleton organization
CORUM:7233	0.0499436884912	0.0833333333333	MYO5A	DLC1-DLGAP1-MYO5A complex

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
KCTD10	TNFAIP1	0.999	0.148	structurally_consistent (dimer)
MYO5C	MYO5A	0.997
MYO5C	MYO5B	0.996	0.182
MYO5A	MYO5B	0.995
CAPZA2	MYO5C	0.994	0.154
MYO5C	DAPK3	0.992	0.052
MYO5C	MYL6B	0.989	0.0411666666667
MYO5C	MYO1C	0.989	0.042
MYO1C	DAPK3	0.985	0.106
KCTD10	MYL6B	0.983	0.048
CAPZA2	MYO5A	0.981
MYO5B	MYO1C	0.981	0.132
TNFAIP1	MYO5B	0.98	0.084
MYO1E	DAPK3	0.977	0.066
KCTD10	MYO5C	0.977	0.038
MYL6B	MYO5B	0.976	0.102
KCTD10	MYO5A	0.976
MYO5C	MYO1E	0.975	0.064
CAMK2G	MYO1C	0.973	0.1
MYO5A	MYO1C	0.971
KCTD10	MYO5B	0.969	0.09
KCTD10	MYO1C	0.968	0.086
MYO5A	MYL6B	0.966
CAPZA2	MYO5B	0.962	0.19259375
KCTD10	MYO1E	0.959	0.074
MYL6B	MYO1E	0.958	0.138
MYO5C	MTFR1	0.958	0.088
CAPZA2	DAPK3	0.954	0.124
MTFR1	MYO1C	0.952	0.08
CAPZA2	MYO1C	0.95	0.378
MYO5B	MYO1E	0.947	0.126
MYO5A	MYO1E	0.946
MYL6B	MYO1C	0.946	0.276
MYO5A	CAMK2G	0.94
TNFAIP1	MYL6B	0.937	0.0940861538462
TNFAIP1	MYO5A	0.932
MYO1E	MYO1C	0.93	0.214
TNFAIP1	MYO5C	0.929	0.08
MTFR1	MYL6B	0.89	0.0200861538462
CAPZA2	TNFAIP1	0.878	0.122
CAPZA2	KCTD10	0.852	0.132
MYO5C	CAMK2G	0.851	0.032
MTFR1	DAPK3	0.796	0.048
TNFAIP1	MYO1E	0.776	0.106
KCTD10	DAPK3	0.773	0.038
MYO5A	DAPK3	0.773
MYO5B	DAPK3	0.773	0.074
TNFAIP1	DAPK3	0.751	0.082
MYL6B	DAPK3	0.749	0.176
CAPZA2	MYO1E	0.731	0.266
KCTD10	MTFR1	0.678	0.076
TNFAIP1	MYO1C	0.673	0.124
MYL6B	CAMK2G	0.613	0.01
MYO5B	CAMK2G	0.509	0.128
MTFR1	MYO5B	0.483	0.081
TNFAIP1	MTFR1	0.483	0.068
MYO1E	CAMK2G	0.421	0.094
MTFR1	MYO5A	0.286
CAPZA2	MYL6B	0.265	0.35
MTFR1	MYO1E	0.222	0.028
CAPZA2	MTFR1	0.203	0.121355471221
CAPZA2	CAMK2G	0.19	0.072
MTFR1	CAMK2G	0.162	0.06
TNFAIP1	CAMK2G	0.15	0.11
CAMK2G	DAPK3	0.145	0.0374545454545
KCTD10	CAMK2G	0.134	0.058

Related Complexes

Genename	Complexes
MYL6B	huMAP3_06763.1 huMAP3_08205.1 huMAP3_09348.1
MYO1C	huMAP3_08867.1 huMAP3_09348.1
PALM2AKAP2	huMAP3_06745.1 huMAP3_08244.1 huMAP3_09348.1
MYO5B	huMAP3_06763.1 huMAP3_08951.1 huMAP3_09348.1
MTFR1	huMAP3_06445.1 huMAP3_07657.1 huMAP3_09348.1
KCTD10	huMAP3_03319.1 huMAP3_06763.1 huMAP3_08951.1 huMAP3_09348.1 huMAP3_14151.1
TNFAIP1	huMAP3_04112.1 huMAP3_08600.1 huMAP3_09348.1 huMAP3_14151.1 huMAP3_14727.1
MYO5C	huMAP3_04161.1 huMAP3_06560.1 huMAP3_07519.1 huMAP3_08244.1 huMAP3_08726.1 huMAP3_09348.1
CAMK2G	huMAP3_08389.1 huMAP3_08867.1 huMAP3_09058.1 huMAP3_09348.1 huMAP3_10642.1 huMAP3_14255.1
DAPK3	huMAP3_09348.1
CAPZA2	huMAP3_02458.1 huMAP3_06652.1 huMAP3_08077.1 huMAP3_09348.1 huMAP3_10870.1 huMAP3_12900.1
MYO5A	huMAP3_06560.1 huMAP3_08244.1 huMAP3_09348.1
MYO1E	huMAP3_08244.1 huMAP3_09348.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_09348.1

Complex Portal: CPX-14932