hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09363.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| INTS5 | Integrator complex subunit 5 (Int5) | 5 | UniProt NCBI |
| INTS6 | Integrator complex subunit 6 (Int6) (DBI-1) (Protein DDX26) (Protein deleted in cancer 1) (DICE1) | 5 | UniProt NCBI |
| INTS9 | Integrator complex subunit 9 (Int9) (Protein related to CPSF subunits of 74 kDa) (RC-74) | 5 | UniProt NCBI |
| INTS4 | Integrator complex subunit 4 (Int4) | 5 | UniProt NCBI |
| INTS1 | Integrator complex subunit 1 (Int1) | 5 | UniProt NCBI |
| INTS12 | Integrator complex subunit 12 (Int12) (PHD finger protein 22) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1153 | 8.31353104481e-18 | 1.0 | INTS9 INTS1 INTS5 INTS6 INTS12 INTS4 | Integrator complex |
| CORUM:1155 | 1.54394147975e-17 | 1.0 | INTS9 INTS1 INTS5 INTS6 INTS12 INTS4 | Integrator-RNAPII complex |
| GO:0032039 | 1.00331471526e-13 | 1.0 | INTS9 INTS1 INTS5 INTS6 INTS12 INTS4 | integrator complex |
| GO:0016180 | 8.51367930471e-13 | 1.0 | INTS9 INTS1 INTS5 INTS6 INTS12 INTS4 | snRNA processing |
| REAC:R-HSA-6807505 | 2.12410345031e-12 | 1.0 | INTS9 INTS1 INTS5 INTS6 INTS12 INTS4 | RNA polymerase II transcribes snRNA genes |
| GO:0016073 | 7.52838076699e-11 | 1.0 | INTS9 INTS1 INTS5 INTS6 INTS12 INTS4 | snRNA metabolic process |
| CORUM:1154 | 4.74939571654e-10 | 0.666666666667 | INTS4 INTS9 INTS5 INTS6 | DSS1 complex |
| GO:0034243 | 9.49811974431e-10 | 1.0 | INTS9 INTS1 INTS5 INTS6 INTS12 INTS4 | regulation of transcription elongation by RNA polymerase II |
| GO:0034472 | 1.09837878454e-09 | 0.833333333333 | INTS12 INTS1 INTS9 INTS5 INTS6 | snRNA 3'-end processing |
| GO:0032784 | 3.21387523899e-09 | 1.0 | INTS9 INTS1 INTS5 INTS6 INTS12 INTS4 | regulation of DNA-templated transcription elongation |
| GO:0006368 | 4.14360714812e-09 | 1.0 | INTS9 INTS1 INTS5 INTS6 INTS12 INTS4 | transcription elongation by RNA polymerase II |
| GO:0006354 | 1.09724346508e-08 | 1.0 | INTS9 INTS1 INTS5 INTS6 INTS12 INTS4 | DNA-templated transcription elongation |
| GO:0031123 | 1.66038655046e-06 | 0.833333333333 | INTS12 INTS1 INTS9 INTS5 INTS6 | RNA 3'-end processing |
| GO:0034470 | 9.20043332604e-06 | 1.0 | INTS9 INTS1 INTS5 INTS6 INTS12 INTS4 | ncRNA processing |
| REAC:R-HSA-73857 | 4.17740470622e-05 | 1.0 | INTS9 INTS1 INTS5 INTS6 INTS12 INTS4 | RNA Polymerase II Transcription |
| REAC:R-HSA-74160 | 8.88513506469e-05 | 1.0 | INTS9 INTS1 INTS5 INTS6 INTS12 INTS4 | Gene expression (Transcription) |
| GO:0034660 | 9.19776227798e-05 | 1.0 | INTS9 INTS1 INTS5 INTS6 INTS12 INTS4 | ncRNA metabolic process |
| GO:0006396 | 0.00102537166899 | 1.0 | INTS9 INTS1 INTS5 INTS6 INTS12 INTS4 | RNA processing |
| GO:0140513 | 0.0092737157774 | 1.0 | INTS9 INTS1 INTS5 INTS6 INTS12 INTS4 | nuclear protein-containing complex |
| WP:WP5345 | 0.0226781844519 | 0.333333333333 | INTS9 INTS4 | 1p36 copy number variation syndrome |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| INTS9 | INTS4 | 1.0 | 0.414 | hein_WMM bioplex3_HEK293 bioplex3_WMM youn_WMM hein () Malo bioplex3_HCT116 gupta_WMM fraction |
| INTS1 | INTS12 | 1.0 | 0.49 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM Malo fraction |
| INTS12 | INTS4 | 1.0 | 0.614 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () |
| INTS5 | INTS4 | 0.998 | 0.906 | hein_WMM bioplex_WMM bioplex3_WMM Malo fraction |
| INTS5 | INTS12 | 0.997 | 0.478 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
| INTS5 | INTS9 | 0.994 | 0.558 | hein_WMM bioplex3_WMM Malo fraction |
| INTS6 | INTS4 | 0.993 | 0.886 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () |
| INTS6 | INTS9 | 0.986 | 0.48 | hein_WMM bioplex3_WMM WMM_only |
| INTS1 | INTS4 | 0.981 | 0.774 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| INTS5 | INTS6 | 0.968 | 0.874 | hein_WMM bioplex3_WMM WMM_only |
| INTS6 | INTS1 | 0.955 | 0.728 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| INTS6 | INTS12 | 0.954 | 0.48 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| INTS12 | INTS9 | 0.936 | 0.564 | hein_WMM youn_WMM WMM_only |
| INTS5 | INTS1 | 0.932 | 0.694 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
| INTS1 | INTS9 | 0.688 | 0.394 | hein_WMM youn_WMM WMM_only |
Related Complexes