hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09383.1
Complex Portal: CPX-15816
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GIGYF1 | GRB10-interacting GYF protein 1 (PERQ amino acid-rich with GYF domain-containing protein 1) | 5 | UniProt NCBI |
| GIGYF2 | GRB10-interacting GYF protein 2 (PERQ amino acid-rich with GYF domain-containing protein 2) (Trinucleotide repeat-containing gene 15 protein) | 5 | UniProt NCBI |
| CAPRIN1 | Caprin-1 (Cell cycle-associated protein 1) (Cytoplasmic activation- and proliferation-associated protein 1) (GPI-anchored membrane protein 1) (GPI-anchored protein p137) (GPI-p137) (p137GPI) (Membrane component chromosome 11 surface marker 1) (RNA granule protein 105) | 5 | UniProt NCBI |
| G3BP1 | Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent DNA helicase VIII) (hDH VIII) (GAP SH3 domain-binding protein 1) | 5 | UniProt NCBI |
| PRRC2A | Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0062029 | 0.0280843539964 | 0.4 | G3BP1 CAPRIN1 | positive regulation of stress granule assembly |
| GO:0062028 | 0.0468008499735 | 0.4 | G3BP1 CAPRIN1 | regulation of stress granule assembly |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CAPRIN1 | G3BP1 | 0.988 | 0.84 | hein_WMM youn () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM | |
| GIGYF2 | PRRC2A | 0.974 | 0.14 | hein_WMM youn () bioplex3_WMM gupta_WMM treiber_WMM WMM_only | |
| PRRC2A | G3BP1 | 0.967 | 0.216 | hein_WMM youn () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction | |
| GIGYF2 | G3BP1 | 0.966 | 0.512 | hein_WMM youn () bioplex3_WMM gupta_WMM WMM_only | |
| PRRC2A | CAPRIN1 | 0.586 | 0.284 | youn () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM | |
| GIGYF2 | CAPRIN1 | 0.053 | 0.462 | youn () bioplex3_WMM gupta_WMM treiber_WMM WMM_only |
Related Complexes