hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_09393.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| XPNPEP1 | Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (X-Pro aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble) | 5 | UniProt NCBI |
| YRDC | Threonylcarbamoyl-AMP synthase (EC 2.7.7.87) (Dopamine receptor-interacting protein 3) (Ischemia/reperfusion-inducible protein homolog) (hIRIP) | 5 | UniProt NCBI |
| SPINDOC | Spindlin interactor and repressor of chromatin-binding protein (SPIN1-docking protein) (SPIN-DOC) | 5 | UniProt NCBI |
| SPIN2B | Spindlin-2B (Spindlin-like protein 2B) (SPIN-2) (SPIN-2B) | 5 | UniProt NCBI |
| RPS6KB2 | Ribosomal protein S6 kinase beta-2 (S6K-beta-2) (S6K2) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 2) (P70S6K2) (p70-S6K 2) (S6 kinase-related kinase) (SRK) (Serine/threonine-protein kinase 14B) (p70 ribosomal S6 kinase beta) (S6K-beta) (p70 S6 kinase beta) (p70 S6K-beta) (p70 S6KB) (p70-beta) | 5 | UniProt NCBI |
| SPIN4 | Spindlin-4 | 3 | UniProt NCBI |
| SPIN1 | Spindlin-1 (Ovarian cancer-related protein) (Spindlin1) | 5 | UniProt NCBI |
| SPIN3 | Spindlin-3 (Spindlin-like protein 3) (SPIN-3) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0035064 | 0.00108303906061 | 0.5 | SPIN4 SPIN3 SPIN2B SPIN1 | methylated histone binding |
| GO:0140034 | 0.00123045452734 | 0.5 | SPIN4 SPIN3 SPIN2B SPIN1 | methylation-dependent protein binding |
| GO:0140030 | 0.0433830596151 | 0.5 | SPIN4 SPIN3 SPIN2B SPIN1 | modification-dependent protein binding |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SPINDOC | SPIN1 | 1.0 | 0.062 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM |
| SPIN2B | SPIN1 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| SPINDOC | SPIN2B | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| SPIN4 | SPIN1 | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| SPINDOC | SPIN3 | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| SPIN2B | SPIN4 | 0.99 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| SPIN1 | SPIN3 | 0.978 | bioplex_WMM bioplex3_WMM WMM_only | |
| YRDC | SPIN1 | 0.974 | 0.024 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| YRDC | SPIN2B | 0.969 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| XPNPEP1 | SPIN2B | 0.956 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| SPIN1 | RPS6KB2 | 0.952 | 0.044 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| SPINDOC | SPIN4 | 0.925 | bioplex_WMM bioplex3_WMM WMM_only | |
| SPIN2B | SPIN3 | 0.866 | bioplex_WMM bioplex3_WMM WMM_only | |
| XPNPEP1 | YRDC | 0.385 | bioplex_WMM bioplex3_WMM WMM_only | |
| YRDC | SPIN4 | 0.367 | bioplex_WMM bioplex3_WMM WMM_only | |
| YRDC | SPINDOC | 0.367 | 0.084 | bioplex_WMM bioplex3_WMM WMM_only |
| XPNPEP1 | SPINDOC | 0.254 | bioplex_WMM bioplex3_WMM WMM_only | |
| XPNPEP1 | SPIN4 | 0.182 | bioplex_WMM bioplex3_WMM WMM_only | |
| XPNPEP1 | SPIN1 | 0.055 | bioplex_WMM bioplex3_WMM WMM_only | |
| XPNPEP1 | SPIN3 | 0.011 | bioplex3_WMM WMM_only |
Related Complexes