hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_09407.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TRAF3 | TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1) (RING-type E3 ubiquitin transferase TRAF3) | 5 | UniProt NCBI |
| ETV7 | Transcription factor ETV7 (ETS translocation variant 7) (ETS-related protein Tel2) (Tel-related Ets factor) (Transcription factor Tel-2) | 5 | UniProt NCBI |
| ETV6 | Transcription factor ETV6 (ETS translocation variant 6) (ETS-related protein Tel1) (Tel) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:05202 | 0.00904723539575 | 0.666666666667 | ETV7 ETV6 | Transcriptional misregulation in cancer |
| WP:WP4876 | 0.0413734636003 | 0.333333333333 | TRAF3 | Activation of NLRP3 inflammasome by SARS CoV 2 |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ETV7 | ETV6 | 0.985 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ETV6 | TRAF3 | 0.985 | 0.136 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| TRAF3 | huMAP3_09407.1 huMAP3_11228.1 huMAP3_14463.1 |
| ETV7 | huMAP3_04027.1 huMAP3_09407.1 |
| ETV6 | huMAP3_04027.1 huMAP3_09407.1 |