hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_09422.1

Complex Portal: CPX-21562

Confidence: Moderate High

Genename	Protein Name	Uniprot Annotation Score	Links
MBIP	MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein)	5	UniProt NCBI
SETD1B	Histone-lysine N-methyltransferase SETD1B (EC 2.1.1.364) (Lysine N-methyltransferase 2G) (SET domain-containing protein 1B) (hSET1B)	5	UniProt NCBI
KAT14	Cysteine-rich protein 2-binding protein (CSRP2-binding protein) (ADA2A-containing complex subunit 2) (ATAC2) (CRP2-binding partner) (CRP2BP) (Lysine acetyltransferase 14)	5	UniProt NCBI
TADA3	Transcriptional adapter 3 (ADA3 homolog) (hADA3) (STAF54) (Transcriptional adapter 3-like) (ADA3-like protein)	5	UniProt NCBI
DR1	Protein Dr1 (Down-regulator of transcription 1) (Negative cofactor 2-beta) (NC2-beta) (TATA-binding protein-associated phosphoprotein)	5	UniProt NCBI
CHD8	Chromodomain-helicase-DNA-binding protein 8 (CHD-8) (EC 3.6.4.12) (ATP-dependent helicase CHD8) (Helicase with SNF2 domain 1)	5	UniProt NCBI
KAT2A	Histone acetyltransferase KAT2A (EC 2.3.1.48) (General control of amino acid synthesis protein 5-like 2) (Histone acetyltransferase GCN5) (hGCN5) (Histone glutaryltransferase KAT2A) (EC 2.3.1.-) (Histone succinyltransferase KAT2A) (EC 2.3.1.-) (Lysine acetyltransferase 2A) (STAF97)	5	UniProt NCBI
KMT2D	Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.364) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2)	5	UniProt NCBI
HCFC2	Host cell factor 2 (HCF-2) (C2 factor)	5	UniProt NCBI
DPY30	Protein dpy-30 homolog (Dpy-30-like protein) (Dpy-30L)	5	UniProt NCBI
RERE	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein)	5	UniProt NCBI
ZZZ3	ZZ-type zinc finger-containing protein 3	5	UniProt NCBI
KAT2B	Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF) (Spermidine acetyltransferase KAT2B) (EC 2.3.1.57)	5	UniProt NCBI
SETD1A	Histone-lysine N-methyltransferase SETD1A (EC 2.1.1.364) (Lysine N-methyltransferase 2F) (SET domain-containing protein 1A) (hSET1A) (Set1/Ash2 histone methyltransferase complex subunit SET1)	5	UniProt NCBI
NCOA6	Nuclear receptor coactivator 6 (Activating signal cointegrator 2) (ASC-2) (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Nuclear receptor-activating protein, 250 kDa) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Thyroid hormone receptor-binding protein)	5	UniProt NCBI
KDM6A	Lysine-specific demethylase 6A (EC 1.14.11.68) (Histone demethylase UTX) (Ubiquitously-transcribed TPR protein on the X chromosome) (Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein) ([histone H3]-trimethyl-L-lysine(27) demethylase 6A)	5	UniProt NCBI
TADA2A	Transcriptional adapter 2-alpha (Transcriptional adapter 2-like) (ADA2-like protein)	5	UniProt NCBI
BOD1L1	Biorientation of chromosomes in cell division protein 1-like 1	5	UniProt NCBI
KMT2A	Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.364) (ALL-1) (CXXC-type zinc finger protein 7) (Cysteine methyltransferase KMT2A) (EC 2.1.1.-) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)]	5	UniProt NCBI
YEATS2	YEATS domain-containing protein 2	5	UniProt NCBI
CXXC1	CXXC-type zinc finger protein 1 (CpG-binding protein) (PHD finger and CXXC domain-containing protein 1)	5	UniProt NCBI
RBBP5	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3)	5	UniProt NCBI
KMT2C	Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.364) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3)	5	UniProt NCBI
WDR5	WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)	5	UniProt NCBI
BOD1	Biorientation of chromosomes in cell division protein 1 (Biorientation defective protein 1) (Protein FAM44B)	5	UniProt NCBI
MDK	Midkine (MK) (Amphiregulin-associated protein) (ARAP) (Midgestation and kidney protein) (Neurite outgrowth-promoting factor 2) (Neurite outgrowth-promoting protein)	5	UniProt NCBI
ASH2L	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein)	5	UniProt NCBI
ATN1	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-9772755	1.16970843497e-55	0.821428571429	KDM6A HCFC2 TADA3 DPY30 BOD1 DR1 ZZZ3 KAT2B ASH2L SETD1A WDR5 NCOA6 KMT2D MBIP BOD1L1 KAT2A KMT2C KMT2A YEATS2 CXXC1 SETD1B RBBP5 KAT14	Formation of WDR5-containing histone-modifying complexes
REAC:R-HSA-212165	2.37070469506e-38	0.821428571429	KDM6A HCFC2 TADA3 DPY30 BOD1 DR1 ZZZ3 KAT2B ASH2L SETD1A WDR5 NCOA6 KMT2D MBIP BOD1L1 KAT2A KMT2C KMT2A YEATS2 CXXC1 SETD1B RBBP5 KAT14	Epigenetic regulation of gene expression
GO:0035097	3.48571247316e-27	0.571428571429	KMT2D WDR5 BOD1L1 DPY30 HCFC2 CXXC1 SETD1B KMT2C SETD1A CHD8 KMT2A NCOA6 KDM6A RBBP5 ASH2L BOD1	histone methyltransferase complex
GO:0034708	1.81986627579e-24	0.571428571429	KMT2D WDR5 BOD1L1 DPY30 HCFC2 CXXC1 SETD1B KMT2C SETD1A CHD8 KMT2A NCOA6 KDM6A RBBP5 ASH2L BOD1	methyltransferase complex
REAC:R-HSA-3247509	3.02919043244e-23	0.642857142857	KMT2D WDR5 RBBP5 ZZZ3 KAT2B KMT2A SETD1A TADA3 MBIP DPY30 KMT2C KAT2A DR1 KAT14 KDM6A SETD1B ASH2L YEATS2	Chromatin modifying enzymes
REAC:R-HSA-4839726	3.02919043244e-23	0.642857142857	KMT2D WDR5 RBBP5 ZZZ3 KAT2B KMT2A SETD1A TADA3 MBIP DPY30 KMT2C KAT2A DR1 KAT14 KDM6A SETD1B ASH2L YEATS2	Chromatin organization
CORUM:6657	8.72020932353e-23	0.321428571429	ZZZ3 WDR5 YEATS2 TADA2A MBIP TADA3 KAT2A KAT14 DR1	ATAC complex, GCN5-linked
GO:1990234	1.54603472454e-22	0.857142857143	KDM6A WDR5 TADA3 DPY30 CHD8 DR1 ZZZ3 KAT2B ASH2L SETD1A HCFC2 NCOA6 KMT2D MBIP BOD1L1 KAT2A KMT2C KMT2A YEATS2 CXXC1 SETD1B RBBP5 KAT14 BOD1	transferase complex
CORUM:6470	1.9139562934e-21	0.321428571429	WDR5 RBBP5 HCFC2 SETD1B ASH2L BOD1L1 BOD1 CXXC1 DPY30	Set1B complex
GO:0048188	5.35310272176e-21	0.357142857143	WDR5 SETD1A HCFC2 SETD1B ASH2L BOD1L1 BOD1 CXXC1 DPY30 RBBP5	Set1C/COMPASS complex
CORUM:6665	1.73762369856e-20	0.321428571429	ZZZ3 WDR5 YEATS2 TADA2A MBIP TADA3 KAT2A KAT14 DR1	ATAC complex, YEATS2-linked
GO:0140672	2.93878417111e-18	0.321428571429	ZZZ3 WDR5 YEATS2 KAT2B MBIP TADA3 KAT2A KAT14 DR1	ATAC complex
REAC:R-HSA-74160	1.07803493937e-17	0.821428571429	KDM6A HCFC2 TADA3 DPY30 BOD1 DR1 ZZZ3 KAT2B ASH2L SETD1A WDR5 NCOA6 KMT2D MBIP BOD1L1 KAT2A KMT2C KMT2A YEATS2 CXXC1 SETD1B RBBP5 KAT14	Gene expression (Transcription)
GO:0090043	9.94514338562e-17	0.321428571429	ZZZ3 WDR5 YEATS2 KAT2B MBIP TADA3 KAT2A KAT14 DR1	regulation of tubulin deacetylation
CORUM:6461	1.5927491229e-16	0.25	KDM6A RBBP5 WDR5 ASH2L DPY30 NCOA6 KMT2C	MLL3 complex
CORUM:6467	1.5927491229e-16	0.25	KMT2D KDM6A WDR5 ASH2L RBBP5 DPY30 NCOA6	MLL4 complex
GO:0044666	4.95821134256e-16	0.285714285714	KMT2D KDM6A WDR5 ASH2L RBBP5 NCOA6 DPY30 KMT2C	MLL3/4 complex
CORUM:6469	5.30248494685e-16	0.25	SETD1A HCFC2 CXXC1 ASH2L RBBP5 WDR5 DPY30	Set1A complex
CORUM:5195	5.30248494685e-16	0.25	KDM6A RBBP5 WDR5 ASH2L DPY30 NCOA6 KMT2C	PTIP-HMT complex
GO:0090042	6.8470739235e-16	0.321428571429	ZZZ3 WDR5 YEATS2 KAT2B MBIP TADA3 KAT2A KAT14 DR1	tubulin deacetylation
GO:1902494	1.66861813096e-15	0.857142857143	KDM6A WDR5 TADA3 DPY30 CHD8 DR1 ZZZ3 KAT2B ASH2L SETD1A HCFC2 NCOA6 KMT2D MBIP BOD1L1 KAT2A KMT2C KMT2A YEATS2 CXXC1 SETD1B RBBP5 KAT14 BOD1	catalytic complex
GO:0090311	2.02303923665e-15	0.321428571429	ZZZ3 WDR5 YEATS2 KAT2B MBIP TADA3 KAT2A KAT14 DR1	regulation of protein deacetylation
CORUM:3075	3.49084014381e-15	0.25	KMT2D KDM6A WDR5 ASH2L RBBP5 NCOA6 KMT2C	UTX-MLL2/3 complex
REAC:R-HSA-8936459	5.17461925127e-14	0.357142857143	KMT2D WDR5 DPY30 KAT2B SETD1B ASH2L SETD1A KMT2C KMT2A RBBP5	RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
GO:0006476	2.82820950289e-13	0.321428571429	ZZZ3 WDR5 YEATS2 KAT2B MBIP TADA3 KAT2A KAT14 DR1	protein deacetylation
GO:0070461	3.7665253749e-13	0.321428571429	ZZZ3 WDR5 YEATS2 KAT2B MBIP TADA3 KAT2A KAT14 DR1	SAGA-type complex
CORUM:6460	6.15334649137e-13	0.214285714286	KMT2D RBBP5 WDR5 ASH2L DPY30 HCFC2	MLL2 complex
REAC:R-HSA-3214841	1.2018516895e-12	0.321428571429	KMT2D RBBP5 WDR5 SETD1B ASH2L SETD1A KMT2C DPY30 KMT2A	PKMTs methylate histone lysines
GO:0035601	1.77143014678e-12	0.321428571429	ZZZ3 WDR5 YEATS2 KAT2B MBIP TADA3 KAT2A KAT14 DR1	protein deacylation
GO:0098732	1.77143014678e-12	0.321428571429	ZZZ3 WDR5 YEATS2 KAT2B MBIP TADA3 KAT2A KAT14 DR1	macromolecule deacylation
CORUM:6851	1.8709334778e-12	0.178571428571	DPY30 RBBP5 WDR5 ASH2L KMT2A	MWRAD complex (MLL1, WDR5, RBBP5, ASH2L, DPY30)
WP:WP5351	8.27273707578e-12	0.25	KDM6A RBBP5 WDR5 ASH2L DPY30 NCOA6 KMT2C	Kleefstra syndrome
CORUM:2730	1.12108741488e-11	0.178571428571	ASH2L CXXC1 WDR5 SETD1B RBBP5	Set1B complex
CORUM:2731	1.12108741488e-11	0.178571428571	SETD1A RBBP5 WDR5 ASH2L CXXC1	Set1A complex
CORUM:1400	3.91865825397e-11	0.178571428571	KMT2D RBBP5 ASH2L KMT2C NCOA6	ASCOM complex
GO:0045995	4.15184952194e-11	0.321428571429	ZZZ3 WDR5 YEATS2 KAT2B MBIP TADA3 KAT2A KAT14 DR1	regulation of embryonic development
GO:0140513	7.75057068016e-11	0.678571428571	KMT2D WDR5 BOD1L1 SETD1A HCFC2 KMT2A CXXC1 BOD1 SETD1B TADA3 DPY30 KMT2C CHD8 NCOA6 DR1 KDM6A RBBP5 ASH2L KAT2A	nuclear protein-containing complex
CORUM:6462	1.04360458684e-10	0.178571428571	DPY30 RBBP5 WDR5 ASH2L KMT2A	MLL1 complex
GO:0071824	2.26277109228e-10	0.535714285714	KMT2D WDR5 RBBP5 ZZZ3 HCFC2 KMT2A SETD1A ASH2L DPY30 CHD8 KAT2B DR1 KDM6A YEATS2 KAT2A	protein-DNA complex organization
REAC:R-HSA-3214847	4.65156783658e-10	0.321428571429	ZZZ3 WDR5 YEATS2 KAT2B MBIP TADA3 KAT2A KAT14 DR1	HATs acetylate histones
CORUM:1401	4.68390599409e-10	0.178571428571	KMT2D KMT2A RBBP5 WDR5 SETD1A	MOF complex
GO:0006325	8.88098978204e-10	0.5	KMT2D WDR5 RBBP5 ZZZ3 HCFC2 KMT2A ASH2L DPY30 CHD8 KAT2B SETD1A KDM6A YEATS2 KAT2A	chromatin organization
REAC:R-HSA-8878171	1.05219201935e-09	0.357142857143	KMT2D WDR5 DPY30 KAT2B SETD1B ASH2L SETD1A KMT2C KMT2A RBBP5	Transcriptional regulation by RUNX1
CORUM:1399	1.13900871017e-09	0.142857142857	KMT2D WDR5 ASH2L RBBP5	WDR5-ASH2L-RBBP5-MLL2 complex
CORUM:6457	1.13900871017e-09	0.142857142857	KMT2A WDR5 ASH2L RBBP5	MLL1 core complex
CORUM:6849	1.13900871017e-09	0.142857142857	DPY30 WDR5 ASH2L RBBP5	WRAD complex (WDR5, RBBP5, ASH2L, DPY30)
GO:0005654	1.75536775437e-09	0.928571428571	ATN1 KDM6A HCFC2 TADA3 DPY30 CHD8 DR1 RERE ZZZ3 KAT2B ASH2L SETD1A WDR5 NCOA6 KMT2D MBIP BOD1L1 KAT2A KMT2C KMT2A YEATS2 CXXC1 SETD1B RBBP5 KAT14 BOD1	nucleoplasm
GO:0000123	2.15044843699e-09	0.321428571429	ZZZ3 WDR5 YEATS2 KAT2B MBIP TADA3 KAT2A KAT14 DR1	histone acetyltransferase complex
REAC:R-HSA-5619507	5.10769406528e-09	0.285714285714	KMT2D KDM6A WDR5 ASH2L RBBP5 NCOA6 DPY30 KMT2C	Activation of HOX genes during differentiation
REAC:R-HSA-5617472	5.10769406528e-09	0.285714285714	KMT2D KDM6A WDR5 ASH2L RBBP5 NCOA6 DPY30 KMT2C	Activation of anterior HOX genes in hindbrain development during early embryogenesis
GO:0071339	5.35253549171e-09	0.25	DPY30 HCFC2 ASH2L RBBP5 CHD8 WDR5 KMT2A	MLL1 complex
GO:0031248	5.85369021248e-09	0.321428571429	ZZZ3 WDR5 YEATS2 KAT2B MBIP TADA3 KAT2A KAT14 DR1	protein acetyltransferase complex
GO:1902493	5.85369021248e-09	0.321428571429	ZZZ3 WDR5 YEATS2 KAT2B MBIP TADA3 KAT2A KAT14 DR1	acetyltransferase complex
GO:0044665	6.84261899566e-09	0.25	DPY30 HCFC2 ASH2L RBBP5 CHD8 WDR5 KMT2A	MLL1/2 complex
GO:0031981	9.05487748708e-09	0.928571428571	ATN1 KDM6A HCFC2 TADA3 DPY30 CHD8 DR1 RERE ZZZ3 KAT2B ASH2L SETD1A WDR5 NCOA6 KMT2D MBIP BOD1L1 KAT2A KMT2C KMT2A YEATS2 CXXC1 SETD1B RBBP5 KAT14 BOD1	nuclear lumen
GO:0051302	1.56549994018e-08	0.321428571429	ZZZ3 WDR5 YEATS2 KAT2B MBIP TADA3 KAT2A KAT14 DR1	regulation of cell division
CORUM:1256	3.97083525293e-08	0.142857142857	KMT2A WDR5 ASH2L RBBP5	MLL-HCF complex
CORUM:1254	3.97083525293e-08	0.142857142857	DPY30 WDR5 ASH2L RBBP5	Menin-associated histone methyltransferase complex
CORUM:5386	1.19722889768e-07	0.178571428571	ASH2L KMT2A WDR5 CHD8 RBBP5	MLL1-WDR5 complex
GO:0006338	1.40612489721e-07	0.428571428571	KMT2D WDR5 RBBP5 KDM6A HCFC2 ASH2L DPY30 CHD8 KAT2B KMT2A YEATS2 KAT2A	chromatin remodeling
GO:0042800	4.05639805944e-07	0.178571428571	KMT2D KMT2A KMT2C SETD1B SETD1A	histone H3K4 methyltransferase activity
GO:0072686	4.92013624356e-07	0.321428571429	ZZZ3 WDR5 YEATS2 KAT2B MBIP TADA3 KAT2A KAT14 DR1	mitotic spindle
GO:0140993	6.15945575436e-07	0.321428571429	KMT2D KDM6A KAT2B KMT2C SETD1B SETD1A KAT2A KMT2A KAT14	histone modifying activity
GO:0006366	6.2498872211e-07	0.678571428571	ATN1 KMT2D RBBP5 KAT2B ZZZ3 HCFC2 KMT2A KMT2C WDR5 MBIP TADA3 DPY30 KAT2A KAT14 ASH2L DR1 YEATS2 NCOA6 CHD8	transcription by RNA polymerase II
CORUM:7367	6.65727810923e-07	0.107142857143	RBBP5 ASH2L WDR5	ASH2L-KDM6B-KDM6B-WDR5 complex
CORUM:6850	6.65727810923e-07	0.107142857143	RBBP5 ASH2L WDR5	WRA complex (WDR5, RBBP5, ASH2L)
GO:0045815	1.22075008667e-06	0.214285714286	RBBP5 WDR5 ASH2L DPY30 KAT2B KMT2A	transcription initiation-coupled chromatin remodeling
GO:0141137	1.49010034438e-06	0.214285714286	RBBP5 WDR5 ASH2L DPY30 KAT2B KMT2A	positive regulation of gene expression, epigenetic
GO:0031974	2.07383799129e-06	0.928571428571	ATN1 KDM6A HCFC2 TADA3 DPY30 CHD8 DR1 RERE ZZZ3 KAT2B ASH2L SETD1A WDR5 NCOA6 KMT2D MBIP BOD1L1 KAT2A KMT2C KMT2A YEATS2 CXXC1 SETD1B RBBP5 KAT14 BOD1	membrane-enclosed lumen
GO:0043233	2.07383799129e-06	0.928571428571	ATN1 KDM6A HCFC2 TADA3 DPY30 CHD8 DR1 RERE ZZZ3 KAT2B ASH2L SETD1A WDR5 NCOA6 KMT2D MBIP BOD1L1 KAT2A KMT2C KMT2A YEATS2 CXXC1 SETD1B RBBP5 KAT14 BOD1	organelle lumen
GO:0070013	2.07383799129e-06	0.928571428571	ATN1 KDM6A HCFC2 TADA3 DPY30 CHD8 DR1 RERE ZZZ3 KAT2B ASH2L SETD1A WDR5 NCOA6 KMT2D MBIP BOD1L1 KAT2A KMT2C KMT2A YEATS2 CXXC1 SETD1B RBBP5 KAT14 BOD1	intracellular organelle lumen
CORUM:6845	2.65949421756e-06	0.107142857143	RBBP5 ASH2L WDR5	NIF1-ASH2L-RBBP5-WDR5 complex
KEGG:00310	4.73375801082e-06	0.178571428571	KMT2D KMT2A KMT2C SETD1B SETD1A	Lysine degradation
GO:0042393	5.27288408057e-06	0.321428571429	KMT2D WDR5 YEATS2 CXXC1 ZZZ3 RBBP5 CHD8 KMT2C KMT2A	histone binding
GO:0005819	5.77760426154e-06	0.357142857143	ZZZ3 WDR5 YEATS2 KAT2B MBIP TADA3 KAT2A KAT14 DR1 BOD1	spindle
CORUM:6340	6.64020420417e-06	0.107142857143	KMT2D ASH2L RBBP5	PITX2-MLL4-ASH2L-RBBP5-PTIP complex
GO:0006351	9.09893476871e-06	0.714285714286	ATN1 KMT2D RBBP5 KAT2B ZZZ3 HCFC2 KMT2A CXXC1 WDR5 MBIP TADA3 DPY30 KMT2C KAT2A KAT14 ASH2L DR1 YEATS2 NCOA6 CHD8	DNA-templated transcription
GO:0006352	9.6095173733e-06	0.285714285714	WDR5 KAT2B DPY30 NCOA6 ASH2L RBBP5 KMT2A DR1	DNA-templated transcription initiation
GO:0032774	1.10949815013e-05	0.714285714286	ATN1 KMT2D RBBP5 KAT2B ZZZ3 HCFC2 KMT2A CXXC1 WDR5 MBIP TADA3 DPY30 KMT2C KAT2A KAT14 ASH2L DR1 YEATS2 NCOA6 CHD8	RNA biosynthetic process
WP:WP2369	1.38011253879e-05	0.178571428571	KMT2D KMT2A KMT2C SETD1B SETD1A	Histone modifications
GO:0051301	1.69487588477e-05	0.321428571429	ZZZ3 WDR5 YEATS2 KAT2B MBIP TADA3 KAT2A KAT14 DR1	cell division
GO:0010468	3.68087538015e-05	0.785714285714	KDM6A HCFC2 TADA3 DPY30 CHD8 DR1 ZZZ3 KAT2B ASH2L WDR5 ATN1 KMT2D NCOA6 MDK MBIP KAT2A KAT14 KMT2A YEATS2 CXXC1 RBBP5 KMT2C	regulation of gene expression
REAC:R-HSA-1266738	6.89896468e-05	0.392857142857	KMT2D WDR5 KDM6A KAT2B KMT2C ASH2L DPY30 KAT2A KMT2A NCOA6 RBBP5	Developmental Biology
GO:0010556	6.92378650553e-05	0.785714285714	KDM6A HCFC2 TADA3 DPY30 CHD8 DR1 ZZZ3 KAT2B ASH2L WDR5 ATN1 KMT2D NCOA6 MDK MBIP KAT2A KAT14 KMT2A YEATS2 CXXC1 RBBP5 KMT2C	regulation of macromolecule biosynthetic process
CORUM:477	7.91725844975e-05	0.107142857143	KAT2B TADA3 TADA2A	PCAF complex
CORUM:471	7.91725844975e-05	0.107142857143	KAT2B TADA3 TADA2A	PCAF complex
GO:0006367	8.52565366466e-05	0.25	KAT2B DPY30 WDR5 ASH2L RBBP5 KMT2A DR1	transcription initiation at RNA polymerase II promoter
GO:0005634	0.00010084946896	0.928571428571	ATN1 KDM6A HCFC2 TADA3 DPY30 CHD8 DR1 RERE ZZZ3 KAT2B ASH2L SETD1A WDR5 NCOA6 KMT2D MBIP BOD1L1 KAT2A KMT2C KMT2A YEATS2 CXXC1 SETD1B RBBP5 KAT14 BOD1	nucleus
GO:0009790	0.000105331656582	0.357142857143	ZZZ3 WDR5 YEATS2 KAT2B KMT2A MBIP TADA3 KAT2A KAT14 DR1	embryo development
GO:0031326	0.000108111092803	0.785714285714	KDM6A HCFC2 TADA3 DPY30 CHD8 DR1 ZZZ3 KAT2B ASH2L WDR5 ATN1 KMT2D NCOA6 MDK MBIP KAT2A KAT14 KMT2A YEATS2 CXXC1 RBBP5 KMT2C	regulation of cellular biosynthetic process
GO:0034654	0.000112011623502	0.714285714286	ATN1 KMT2D RBBP5 KAT2B ZZZ3 HCFC2 KMT2A CXXC1 WDR5 MBIP TADA3 DPY30 KMT2C KAT2A KAT14 ASH2L DR1 YEATS2 NCOA6 CHD8	nucleobase-containing compound biosynthetic process
GO:0009889	0.000121852766505	0.785714285714	KDM6A HCFC2 TADA3 DPY30 CHD8 DR1 ZZZ3 KAT2B ASH2L WDR5 ATN1 KMT2D NCOA6 MDK MBIP KAT2A KAT14 KMT2A YEATS2 CXXC1 RBBP5 KMT2C	regulation of biosynthetic process
GO:0003712	0.000133097710433	0.357142857143	KMT2D NCOA6 YEATS2 HCFC2 KMT2C ATN1 TADA3 KAT2A KAT2B RERE	transcription coregulator activity
GO:0018130	0.000156286216495	0.714285714286	ATN1 KMT2D RBBP5 KAT2B ZZZ3 HCFC2 KMT2A CXXC1 WDR5 MBIP TADA3 DPY30 KMT2C KAT2A KAT14 ASH2L DR1 YEATS2 NCOA6 CHD8	heterocycle biosynthetic process
GO:0019438	0.000159345023745	0.714285714286	ATN1 KMT2D RBBP5 KAT2B ZZZ3 HCFC2 KMT2A CXXC1 WDR5 MBIP TADA3 DPY30 KMT2C KAT2A KAT14 ASH2L DR1 YEATS2 NCOA6 CHD8	aromatic compound biosynthetic process
HP:0007655	0.000174265920424	0.107142857143	KMT2D KMT2A KDM6A	Eversion of lateral third of lower eyelids
REAC:R-HSA-3769402	0.000192578763589	0.142857142857	KMT2D ASH2L CHD8 RBBP5	Deactivation of the beta-catenin transactivating complex
KEGG:04934	0.000221858189908	0.178571428571	KMT2D RBBP5 WDR5 ASH2L KMT2A	Cushing syndrome
GO:1901362	0.000269977532105	0.714285714286	ATN1 KMT2D RBBP5 KAT2B ZZZ3 HCFC2 KMT2A CXXC1 WDR5 MBIP TADA3 DPY30 KMT2C KAT2A KAT14 ASH2L DR1 YEATS2 NCOA6 CHD8	organic cyclic compound biosynthetic process
GO:0140938	0.000276186233542	0.178571428571	KMT2D KMT2A KMT2C SETD1B SETD1A	histone H3 methyltransferase activity
CORUM:2721	0.00036663738488	0.107142857143	SETD1A ASH2L WDR5	HCF-1 complex
GO:0000122	0.000380897596319	0.392857142857	YEATS2 WDR5 KAT2B HCFC2 ATN1 MBIP TADA3 KAT2A KAT14 DR1 CHD8	negative regulation of transcription by RNA polymerase II
GO:0060255	0.000400318439137	0.821428571429	ATN1 KDM6A HCFC2 TADA3 DPY30 BOD1 DR1 ZZZ3 KAT2B ASH2L WDR5 NCOA6 KMT2D MDK MBIP KAT2A KAT14 KMT2A YEATS2 CXXC1 RBBP5 KMT2C CHD8	regulation of macromolecule metabolic process
GO:0031323	0.000420773815295	0.821428571429	ATN1 KDM6A HCFC2 TADA3 DPY30 BOD1 DR1 ZZZ3 KAT2B ASH2L WDR5 NCOA6 KMT2D MDK MBIP KAT2A KAT14 KMT2A YEATS2 CXXC1 RBBP5 KMT2C CHD8	regulation of cellular metabolic process
REAC:R-HSA-212436	0.00042842633635	0.392857142857	KMT2D WDR5 SETD1A KAT2B SETD1B ASH2L DPY30 KAT2A KMT2C KMT2A RBBP5	Generic Transcription Pathway
GO:0006357	0.000476658321215	0.571428571429	KMT2D WDR5 KAT2B ZZZ3 HCFC2 KMT2A KMT2C ATN1 MBIP TADA3 KAT2A KAT14 DR1 YEATS2 NCOA6 CHD8	regulation of transcription by RNA polymerase II
GO:0032991	0.00068151565623	0.857142857143	KDM6A WDR5 TADA3 DPY30 CHD8 DR1 ZZZ3 KAT2B ASH2L SETD1A HCFC2 NCOA6 KMT2D MBIP BOD1L1 KAT2A KMT2C KMT2A YEATS2 CXXC1 SETD1B RBBP5 KAT14 BOD1	protein-containing complex
GO:0040029	0.000917123335325	0.25	KMT2D DPY30 WDR5 ASH2L RBBP5 KAT2B KMT2A	epigenetic regulation of gene expression
HP:0025352	0.00104023979076	0.107142857143	KMT2C CHD8 ATN1	Typically de novo
GO:0042054	0.00114946122256	0.178571428571	KMT2D KMT2A KMT2C SETD1B SETD1A	histone methyltransferase activity
REAC:R-HSA-73857	0.00126016659529	0.392857142857	KMT2D WDR5 SETD1A KAT2B SETD1B ASH2L DPY30 KAT2A KMT2C KMT2A RBBP5	RNA Polymerase II Transcription
GO:0016279	0.00128461292036	0.178571428571	KMT2D KMT2A KMT2C SETD1B SETD1A	protein-lysine N-methyltransferase activity
GO:0016278	0.00143210364214	0.178571428571	KMT2D KMT2A KMT2C SETD1B SETD1A	lysine N-methyltransferase activity
HP:0011298	0.00159342152617	0.142857142857	KMT2D KMT2A ATN1 KDM6A	Prominent digit pad
GO:0016070	0.00180645439735	0.714285714286	ATN1 KMT2D RBBP5 KAT2B ZZZ3 HCFC2 KMT2A CXXC1 WDR5 MBIP TADA3 DPY30 KMT2C KAT2A KAT14 ASH2L DR1 YEATS2 NCOA6 CHD8	RNA metabolic process
GO:0090304	0.00197052949981	0.75	ATN1 KMT2D RBBP5 KAT2B ZZZ3 HCFC2 KMT2A CXXC1 WDR5 MBIP TADA3 DPY30 KMT2C KAT2A KAT14 ASH2L DR1 BOD1L1 YEATS2 NCOA6 CHD8	nucleic acid metabolic process
CORUM:1257	0.00211205293269	0.107142857143	KMT2A WDR5 RBBP5	ALL-1 supercomplex
GO:0019222	0.0023914731591	0.821428571429	ATN1 KDM6A HCFC2 TADA3 DPY30 BOD1 DR1 ZZZ3 KAT2B ASH2L WDR5 NCOA6 KMT2D MDK MBIP KAT2A KAT14 KMT2A YEATS2 CXXC1 RBBP5 KMT2C CHD8	regulation of metabolic process
GO:0043933	0.00276613167356	0.535714285714	KMT2D WDR5 RBBP5 ZZZ3 HCFC2 KMT2A SETD1A ASH2L DPY30 CHD8 KAT2B DR1 KDM6A YEATS2 KAT2A	protein-containing complex organization
GO:0010557	0.00302482503395	0.535714285714	KMT2D WDR5 RBBP5 KAT2B CXXC1 MBIP TADA3 DPY30 KMT2C CHD8 KMT2A NCOA6 MDK ASH2L KAT2A	positive regulation of macromolecule biosynthetic process
GO:0030674	0.00332997578111	0.392857142857	KMT2D NCOA6 ZZZ3 HCFC2 KMT2C ATN1 TADA3 KAT2A KAT2B RERE YEATS2	protein-macromolecule adaptor activity
GO:0044271	0.0040820030388	0.714285714286	ATN1 KMT2D RBBP5 KAT2B ZZZ3 HCFC2 KMT2A CXXC1 WDR5 MBIP TADA3 DPY30 KMT2C KAT2A KAT14 ASH2L DR1 YEATS2 NCOA6 CHD8	cellular nitrogen compound biosynthetic process
GO:0006355	0.00420813211686	0.607142857143	KMT2D WDR5 KAT2B ZZZ3 HCFC2 KMT2A CXXC1 ATN1 MBIP TADA3 KMT2C KAT2A KAT14 DR1 YEATS2 NCOA6 CHD8	regulation of DNA-templated transcription
GO:0031328	0.00450407783495	0.535714285714	KMT2D WDR5 RBBP5 KAT2B CXXC1 MBIP TADA3 DPY30 KMT2C CHD8 KMT2A NCOA6 MDK ASH2L KAT2A	positive regulation of cellular biosynthetic process
GO:2001141	0.00461109507294	0.607142857143	KMT2D WDR5 KAT2B ZZZ3 HCFC2 KMT2A CXXC1 ATN1 MBIP TADA3 KMT2C KAT2A KAT14 DR1 YEATS2 NCOA6 CHD8	regulation of RNA biosynthetic process
GO:0009891	0.00490770884378	0.535714285714	KMT2D WDR5 RBBP5 KAT2B CXXC1 MBIP TADA3 DPY30 KMT2C CHD8 KMT2A NCOA6 MDK ASH2L KAT2A	positive regulation of biosynthetic process
GO:0010467	0.00701066915194	0.785714285714	KDM6A HCFC2 TADA3 DPY30 CHD8 DR1 ZZZ3 KAT2B ASH2L WDR5 ATN1 KMT2D NCOA6 MDK MBIP KAT2A KAT14 KMT2A YEATS2 CXXC1 RBBP5 KMT2C	gene expression
CORUM:6641	0.0104022870287	0.0714285714286	TADA3 KAT2A	USP22-SAGA complex
GO:0003713	0.0112840626409	0.25	KMT2D HCFC2 KMT2C TADA3 KAT2A KAT2B NCOA6	transcription coactivator activity
GO:0045892	0.0124048323739	0.392857142857	YEATS2 WDR5 KAT2B HCFC2 ATN1 MBIP TADA3 KAT2A KAT14 DR1 CHD8	negative regulation of DNA-templated transcription
HPA:0301361	0.0134224606314	0.321428571429	KDM6A DPY30 KAT2B KMT2A CXXC1 MBIP SETD1A DR1 NCOA6	lung; alveolar cells type I[>=Low]
GO:1902679	0.0139301099641	0.392857142857	YEATS2 WDR5 KAT2B HCFC2 ATN1 MBIP TADA3 KAT2A KAT14 DR1 CHD8	negative regulation of RNA biosynthetic process
GO:0008170	0.0139318224452	0.178571428571	KMT2D KMT2A KMT2C SETD1B SETD1A	N-methyltransferase activity
GO:0006139	0.0141269726601	0.75	ATN1 KMT2D RBBP5 KAT2B ZZZ3 HCFC2 KMT2A CXXC1 WDR5 MBIP TADA3 DPY30 KMT2C KAT2A KAT14 ASH2L DR1 BOD1L1 YEATS2 NCOA6 CHD8	nucleobase-containing compound metabolic process
GO:0060090	0.0163456341805	0.392857142857	KMT2D NCOA6 ZZZ3 HCFC2 KMT2C ATN1 TADA3 KAT2A KAT2B RERE YEATS2	molecular adaptor activity
CORUM:438	0.0166783495775	0.0714285714286	TADA3 KAT2A	GCN5-TRRAP histone acetyltransferase complex
GO:0008276	0.0169738470018	0.178571428571	KMT2D KMT2A KMT2C SETD1B SETD1A	protein methyltransferase activity
HP:0002000	0.0172329267402	0.107142857143	KMT2D KMT2A KDM6A	Short columella
HP:0000437	0.0195577592541	0.107142857143	KMT2D KMT2A KDM6A	Depressed nasal tip
GO:0140030	0.0216354852793	0.214285714286	ZZZ3 YEATS2 WDR5 CHD8 CXXC1 KMT2A	modification-dependent protein binding
GO:0051252	0.0224959851595	0.607142857143	KMT2D WDR5 KAT2B ZZZ3 HCFC2 KMT2A CXXC1 ATN1 MBIP TADA3 KMT2C KAT2A KAT14 DR1 YEATS2 NCOA6 CHD8	regulation of RNA metabolic process
HP:0009929	0.0236234911256	0.142857142857	KMT2D KMT2A ATN1 KDM6A	Abnormal columella morphology
GO:0046483	0.0241967109311	0.75	ATN1 KMT2D RBBP5 KAT2B ZZZ3 HCFC2 KMT2A CXXC1 WDR5 MBIP TADA3 DPY30 KMT2C KAT2A KAT14 ASH2L DR1 BOD1L1 YEATS2 NCOA6 CHD8	heterocycle metabolic process
CORUM:475	0.0244036311648	0.0714285714286	TADA3 KAT2A	STAGA complex
GO:0006725	0.0256208590618	0.75	ATN1 KMT2D RBBP5 KAT2B ZZZ3 HCFC2 KMT2A CXXC1 WDR5 MBIP TADA3 DPY30 KMT2C KAT2A KAT14 ASH2L DR1 BOD1L1 YEATS2 NCOA6 CHD8	cellular aromatic compound metabolic process
CORUM:476	0.0288064787625	0.0714285714286	TADA3 KAT2A	STAGA complex
HP:0005218	0.0294267148713	0.0714285714286	KMT2D KDM6A	Anoperineal fistula
HP:0010447	0.0294267148713	0.0714285714286	KMT2D KDM6A	Anal fistula
GO:0010628	0.032060347098	0.357142857143	MDK RBBP5 KAT2B MBIP TADA3 DPY30 KAT2A WDR5 KMT2A ASH2L	positive regulation of gene expression
GO:0009059	0.0347184633597	0.785714285714	KDM6A HCFC2 TADA3 DPY30 CHD8 DR1 ZZZ3 KAT2B ASH2L WDR5 ATN1 KMT2D NCOA6 MDK MBIP KAT2A KAT14 KMT2A YEATS2 CXXC1 RBBP5 KMT2C	macromolecule biosynthetic process
GO:0051253	0.0371804537256	0.392857142857	YEATS2 WDR5 KAT2B HCFC2 ATN1 MBIP TADA3 KAT2A KAT14 DR1 CHD8	negative regulation of RNA metabolic process
GO:0000785	0.039957429062	0.392857142857	ZZZ3 WDR5 YEATS2 KAT2B MBIP TADA3 SETD1A KAT2A KAT14 DR1 CHD8	chromatin
CORUM:445	0.0441603274265	0.0714285714286	TADA3 KAT2A	TFTC complex (TATA-binding protein-free TAF-II-containing complex)
CORUM:455	0.0441603274265	0.0714285714286	TADA3 KAT2A	TFTC complex (TATA-binding protein-free TAF-II-containing complex)
CORUM:456	0.0441603274265	0.0714285714286	TADA3 KAT2A	TFTC complex (TATA-binding protein-free TAF-II-containing complex)
CORUM:462	0.0441603274265	0.0714285714286	TADA3 KAT2A	TFTC complex (TATA-binding protein-free TAF-II-containing complex)
HP:0004378	0.0482297950582	0.178571428571	KMT2D KDM6A KMT2C ATN1 RERE	Abnormality of the anus
GO:1901360	0.0496555715363	0.75	ATN1 KMT2D RBBP5 KAT2B ZZZ3 HCFC2 KMT2A CXXC1 WDR5 MBIP TADA3 DPY30 KMT2C KAT2A KAT14 ASH2L DR1 BOD1L1 YEATS2 NCOA6 CHD8	organic cyclic compound metabolic process
CORUM:470	0.0499890868847	0.0714285714286	TADA3 KAT2A	TFTC complex (TATA-binding protein-free TAF-II-containing complex)
CORUM:513	0.0499890868847	0.0714285714286	TADA3 KAT2A	TFTC complex (TATA-binding protein-free TAF-II-containing complex)

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
RBBP5	ASH2L	1.0	0.438	structurally_consistent (dimer)
CXXC1	RBBP5	1.0	0.27	structurally_consistent (dimer)
TADA3	ZZZ3	1.0	0.186	mutually_exclusive (P61964)
RBBP5	SETD1A	1.0	0.208	mutually_exclusive (P61964)
MBIP	ZZZ3	1.0	0.288	mutually_exclusive (P61964)
SETD1B	RBBP5	1.0	0.106
CXXC1	SETD1A	1.0	0.46
MBIP	TADA3	1.0	0.204	mutually_exclusive (P61964)
TADA3	YEATS2	1.0	0.402	mutually_exclusive (P61964)
DR1	MBIP	1.0	0.226
KMT2A	HCFC2	1.0	0.144
WDR5	RBBP5	1.0	0.574	structurally_consistent (dimer)
CXXC1	WDR5	1.0	0.464	structurally_consistent (dimer)
CXXC1	ASH2L	1.0	0.474	structurally_consistent (Q15291)
TADA3	KAT2A	1.0	0.286
MBIP	YEATS2	1.0	0.186	mutually_exclusive (P61964)
DR1	ZZZ3	1.0	0.1
CXXC1	SETD1B	1.0	0.236
HCFC2	ASH2L	0.999	0.276
MBIP	KAT14	0.999	0.282
DR1	KAT2A	0.999	0.094	structurally_consistent (dimer)
MBIP	KAT2A	0.999	0.254
CXXC1	BOD1L1	0.999	0.256
HCFC2	SETD1A	0.999	0.462
KAT14	TADA3	0.999	0.26
DR1	KAT14	0.999	0.166	structurally_consistent (dimer)
DR1	TADA3	0.999	0.174
KAT2A	TADA2A	0.999
WDR5	MBIP	0.999	0.192	structurally_consistent (dimer)
WDR5	YEATS2	0.999	0.298	structurally_consistent (dimer)
DR1	YEATS2	0.999	0.188	structurally_consistent (dimer)
SETD1B	ASH2L	0.999	0.22
BOD1L1	SETD1A	0.999	0.392
BOD1L1	HCFC2	0.999	0.188
CXXC1	HCFC2	0.999	0.306
DR1	TADA2A	0.999
TADA3	TADA2A	0.999
YEATS2	ZZZ3	0.999	0.318	mutually_exclusive (P61964)
SETD1A	ASH2L	0.999	0.566
CXXC1	BOD1	0.999	0.128
YEATS2	KAT2A	0.999	0.248
KMT2A	RBBP5	0.999	0.156
BOD1L1	RBBP5	0.999	0.324
WDR5	BOD1L1	0.999	0.198
BOD1	ASH2L	0.999	0.182
MBIP	KAT2B	0.999
KAT2A	ZZZ3	0.998	0.276
MBIP	TADA2A	0.998		mutually_exclusive (P61964)
WDR5	ASH2L	0.998	0.236	structurally_consistent (Q15291)
RBBP5	KMT2D	0.998	0.11
WDR5	SETD1A	0.998	0.168	structurally_consistent (dimer)
RBBP5	BOD1	0.998	0.134
DPY30	RBBP5	0.998	0.466
BOD1L1	ASH2L	0.998	0.386
ZZZ3	TADA2A	0.998		mutually_exclusive (P61964)
YEATS2	TADA2A	0.998		mutually_exclusive (P61964)
KMT2A	ASH2L	0.997	0.196
WDR5	ZZZ3	0.997	0.286	structurally_consistent (dimer)
CXXC1	DPY30	0.997	0.234	structurally_consistent (P61964)
KAT2B	TADA3	0.997
DPY30	ASH2L	0.997	0.414
KAT14	YEATS2	0.996	0.224
WDR5	TADA2A	0.996		structurally_consistent (dimer)
KAT14	KAT2A	0.996	0.268
SETD1B	BOD1	0.996	0.166
DR1	WDR5	0.996	0.07
HCFC2	RBBP5	0.996	0.348
WDR5	KMT2A	0.996	0.228
DR1	KAT2B	0.995
KAT2B	KAT14	0.995		mutually_exclusive (Q96ES7)
WDR5	KAT2A	0.995	0.326	structurally_consistent (dimer)
WDR5	KAT14	0.994	0.28
ATN1	WDR5	0.994	0.142	structurally_consistent (dimer)
WDR5	SETD1B	0.993	0.172
KDM6A	RBBP5	0.993	0.316	mutually_exclusive (P61964)
WDR5	KAT2B	0.992		mutually_exclusive (Q96ES7) structurally_consistent (dimer)
KAT14	ZZZ3	0.991	0.304
KAT14	TADA2A	0.989
WDR5	HCFC2	0.988	0.192
RERE	WDR5	0.986	0.19
RERE	ZZZ3	0.986	0.178
KAT2B	TADA2A	0.986
KAT2B	YEATS2	0.985
NCOA6	WDR5	0.984	0.352
WDR5	TADA3	0.984	0.202	structurally_consistent (dimer)
KDM6A	KMT2D	0.983	0.192
WDR5	KMT2D	0.982	0.0641691542289
WDR5	KDM6A	0.981	0.312	structurally_consistent (dimer)
KAT2B	ZZZ3	0.98
BOD1L1	KDM6A	0.98	0.15
ASH2L	KMT2D	0.978	0.09203125
SETD1B	KDM6A	0.976	0.28
KMT2A	KDM6A	0.976	0.284
ZZZ3	CHD8	0.976	0.214
MBIP	KMT2D	0.973	0.204
WDR5	DPY30	0.973	0.3825	structurally_consistent (dimer)
KDM6A	ASH2L	0.973	0.204
RBBP5	KMT2C	0.972	0.094
YEATS2	KMT2D	0.971	0.264
RERE	MBIP	0.971	0.132
KMT2A	KMT2D	0.969	0.118
BOD1L1	KMT2D	0.968	0.098
SETD1B	KMT2D	0.966	0.124
SETD1A	MDK	0.966	0.068
RERE	KMT2D	0.966	0.184
CXXC1	MDK	0.965	0.08
ATN1	RBBP5	0.964	0.12	mutually_exclusive (P61964)
WDR5	BOD1	0.962	0.222
CXXC1	KMT2A	0.962	0.196
MBIP	CHD8	0.961	0.132
SETD1B	SETD1A	0.96	0.304
ZZZ3	KMT2D	0.956	0.164
KMT2C	ASH2L	0.955	0.082
BOD1L1	BOD1	0.955	0.132
DR1	RBBP5	0.951	0.064
SETD1A	KMT2D	0.95	0.102
BOD1L1	KMT2A	0.947	0.18
SETD1B	KMT2A	0.946	0.222
HCFC2	DPY30	0.945	0.34
BOD1L1	SETD1B	0.945	0.196
KAT2B	KAT2A	0.944
CXXC1	KDM6A	0.943	0.208
KMT2A	SETD1A	0.941	0.204
BOD1	SETD1A	0.94	0.062
RERE	YEATS2	0.937	0.234
KDM6A	SETD1A	0.93	0.228
CXXC1	MBIP	0.93	0.184
ATN1	RERE	0.929	0.28
YEATS2	CHD8	0.924	0.266
CXXC1	KMT2D	0.922	0.218
ATN1	SETD1A	0.92	0.15	mutually_exclusive (P61964)
CXXC1	ATN1	0.902	0.316
CXXC1	RERE	0.889	0.322
SETD1B	HCFC2	0.842	0.154
NCOA6	ASH2L	0.835	0.318
KDM6A	DPY30	0.824	0.212
RERE	SETD1A	0.821	0.182
ATN1	ASH2L	0.811	0.194
NCOA6	RBBP5	0.805	0.346
KDM6A	BOD1	0.798	0.152
NCOA6	BOD1	0.798	0.134
BOD1	KMT2D	0.798	0.134
NCOA6	SETD1B	0.791	0.192
RERE	DPY30	0.78	0.216
CXXC1	ZZZ3	0.779	0.194
HCFC2	KDM6A	0.769	0.22
NCOA6	KMT2D	0.759	0.118
MBIP	RBBP5	0.755	0.096	mutually_exclusive (P61964)
ATN1	KMT2A	0.712	0.152
DR1	ASH2L	0.705	0.186
DPY30	BOD1	0.673	0.104
NCOA6	KDM6A	0.671	0.268
NCOA6	BOD1L1	0.641	0.242
KAT14	CHD8	0.608	0.1
DPY30	SETD1A	0.606	0.154
RBBP5	MDK	0.604	0.044
ATN1	HCFC2	0.592	0.218
DPY30	KMT2D	0.589	0.184
NCOA6	KMT2A	0.533	0.14
KAT14	RBBP5	0.506	0.072
BOD1L1	DPY30	0.499	0.362
CXXC1	NCOA6	0.469	0.216
SETD1B	DPY30	0.452	0.212
HCFC2	KMT2D	0.449	0.08
BOD1L1	MDK	0.44	0.056
ATN1	BOD1L1	0.431	0.186
RERE	RBBP5	0.427	0.14
NCOA6	ATN1	0.417	0.296
ATN1	SETD1B	0.401	0.318
ATN1	KMT2D	0.4	0.152
NCOA6	SETD1A	0.398	0.206
ATN1	MBIP	0.394	0.164	mutually_exclusive (P61964)
ATN1	KDM6A	0.389	0.226
TADA2A	CHD8	0.386
RERE	KMT2A	0.378	0.232
KMT2A	BOD1	0.373	0.15
KMT2A	DPY30	0.362	0.078
RERE	SETD1B	0.357	0.284
ATN1	BOD1	0.357	0.098
RERE	KDM6A	0.357	0.266
NCOA6	RERE	0.357	0.178
MBIP	KDM6A	0.356	0.324
TADA2A	KMT2A	0.354
RERE	BOD1	0.353	0.182
KAT2A	KMT2A	0.332	0.252
CXXC1	YEATS2	0.327	0.196
RERE	BOD1L1	0.324	0.14
TADA3	CHD8	0.321	0.122
NCOA6	MBIP	0.318	0.286
TADA3	KMT2A	0.307	0.298
DR1	KDM6A	0.306	0.11
NCOA6	HCFC2	0.293	0.212
NCOA6	KMT2C	0.288	0.126
HCFC2	BOD1	0.276	0.236
DR1	KMT2D	0.274	0.096
NCOA6	TADA2A	0.273
KAT2B	KDM6A	0.273
NCOA6	KAT2B	0.273
TADA2A	KDM6A	0.273		mutually_exclusive (P61964)
KDM6A	KMT2C	0.266	0.166
NCOA6	ZZZ3	0.263	0.2
TADA3	KMT2D	0.256	0.128
KAT14	KMT2D	0.254	0.338824742268
TADA3	KDM6A	0.251	0.272	mutually_exclusive (P61964)
NCOA6	KAT2A	0.25	0.226
KAT2A	KDM6A	0.25	0.25
YEATS2	KDM6A	0.248	0.328
DR1	NCOA6	0.247	0.264
RERE	TADA2A	0.242
RERE	KAT2B	0.242
TADA3	BOD1L1	0.24	0.204
ATN1	ZZZ3	0.239	0.202	mutually_exclusive (P61964)
DR1	SETD1A	0.236	0.082
KAT2B	CHD8	0.234
DR1	SETD1B	0.232	0.182
ZZZ3	KDM6A	0.23	0.236	mutually_exclusive (P61964)
KAT2A	CHD8	0.23	0.134615384615
NCOA6	TADA3	0.227	0.404
KAT2B	KMT2A	0.227
DR1	KMT2A	0.226	0.1
ASH2L	MDK	0.225	0.098
ATN1	KAT14	0.225	0.108
KAT2A	KMT2D	0.223	0.222
ATN1	KAT2A	0.223	0.248
ATN1	TADA3	0.223	0.19	mutually_exclusive (P61964)
RERE	TADA3	0.22	0.24
RERE	KAT2A	0.22	0.182
KAT2B	KMT2D	0.215
ATN1	TADA2A	0.215		mutually_exclusive (P61964)
TADA2A	KMT2D	0.215
ATN1	KAT2B	0.215
DR1	ATN1	0.214	0.086
ATN1	KMT2C	0.21	0.128
MBIP	BOD1	0.207	0.198
DR1	CHD8	0.206	0.034
DR1	BOD1L1	0.205	0.046
CXXC1	TADA2A	0.195
DR1	RERE	0.192	0.082
ZZZ3	BOD1L1	0.186	0.098
ZZZ3	DPY30	0.185	0.196	mutually_exclusive (P61964)
MBIP	SETD1B	0.182	0.136
KAT14	SETD1B	0.182	0.188
KAT2B	BOD1L1	0.182
MBIP	BOD1L1	0.18	0.138
RERE	ASH2L	0.178	0.192
TADA3	SETD1B	0.177	0.188
KAT14	KDM6A	0.173	0.286
TADA3	RBBP5	0.171	0.278	mutually_exclusive (P61964)
YEATS2	SETD1B	0.169	0.14
KAT2A	SETD1B	0.168	0.146
TADA2A	SETD1B	0.168
KAT2B	SETD1B	0.168
NCOA6	KAT14	0.164	0.192
DR1	CXXC1	0.161	0.09
DR1	BOD1	0.157	0.16
TADA2A	BOD1	0.146
KAT2B	BOD1	0.144
ZZZ3	RBBP5	0.144	0.142	mutually_exclusive (P61964)
RERE	KAT14	0.143	0.296
YEATS2	BOD1L1	0.142	0.15
DR1	HCFC2	0.142	0.13
ZZZ3	SETD1B	0.133	0.228
RERE	HCFC2	0.131	0.264
TADA2A	SETD1A	0.13
KAT2B	SETD1A	0.129
KAT2A	BOD1	0.128	0.134
ATN1	DPY30	0.128	0.222	mutually_exclusive (P61964)
CXXC1	CHD8	0.127	0.126
ZZZ3	BOD1	0.126	0.114
TADA3	SETD1A	0.123	0.186	mutually_exclusive (P61964)
KAT2A	BOD1L1	0.12	0.144
MBIP	KMT2A	0.119	0.234
TADA2A	BOD1L1	0.117
NCOA6	DPY30	0.117	0.366
KAT14	BOD1L1	0.114	0.11
ATN1	YEATS2	0.113	0.256	mutually_exclusive (P61964)
ZZZ3	SETD1A	0.105	0.112	mutually_exclusive (P61964)
MBIP	DPY30	0.103	0.178
MBIP	KMT2C	0.102	0.064
KAT2B	RBBP5	0.102		mutually_exclusive (P61964)
NCOA6	YEATS2	0.102	0.224
CXXC1	KAT2A	0.101	0.21
KAT2A	RBBP5	0.1	0.236	mutually_exclusive (P61964)
TADA3	BOD1	0.099	0.178
KMT2C	KMT2D	0.099	0.046
MBIP	SETD1A	0.096	0.112	mutually_exclusive (P61964)
CXXC1	KMT2C	0.095	0.144
KMT2C	SETD1A	0.095	0.144
KAT14	BOD1	0.095	0.154
TADA2A	RBBP5	0.095
TADA3	ASH2L	0.091	0.2
ZZZ3	KMT2A	0.085	0.184
HCFC2	KMT2C	0.082	0.112
WDR5	KMT2C	0.081	0.042
BOD1L1	KMT2C	0.079	0.096
KMT2C	BOD1	0.079	0.096
RERE	KMT2C	0.079	0.104
SETD1B	KMT2C	0.079	0.104
DPY30	KMT2C	0.078	0.1
KAT2A	SETD1A	0.074	0.176
MBIP	ASH2L	0.071	0.106
KMT2A	KMT2C	0.071	0.07
YEATS2	KMT2A	0.069	0.098
YEATS2	DPY30	0.067	0.176
CXXC1	TADA3	0.063	0.132
MBIP	HCFC2	0.058	0.09
CXXC1	KAT2B	0.057
ZZZ3	ASH2L	0.055	0.18
KAT14	SETD1A	0.055	0.182
CXXC1	KAT14	0.054	0.144
YEATS2	BOD1	0.051	0.18
TADA2A	DPY30	0.047
KAT14	KMT2A	0.046	0.302
KAT2A	DPY30	0.045	0.136
KAT2B	ASH2L	0.041
YEATS2	RBBP5	0.039	0.184	mutually_exclusive (P61964)
DR1	DPY30	0.038	0.422
CHD8	KMT2D	0.034	0.228
SETD1B	CHD8	0.033	0.098
TADA2A	ASH2L	0.032
YEATS2	SETD1A	0.031	0.212	mutually_exclusive (P61964)
BOD1L1	CHD8	0.03	0.152
CHD8	ASH2L	0.028	0.09
YEATS2	ASH2L	0.027	0.192
YEATS2	HCFC2	0.025	0.12
KAT14	ASH2L	0.025	0.176
KDM6A	CHD8	0.025	0.246615384615
KAT2B	HCFC2	0.025
KAT2A	HCFC2	0.024	0.156
CHD8	SETD1A	0.024	0.06
TADA2A	HCFC2	0.024
KAT2A	ASH2L	0.023	0.296
TADA3	HCFC2	0.021	0.202
ZZZ3	HCFC2	0.02	0.078
KMT2A	CHD8	0.016	0.146
DPY30	CHD8	0.016	0.07
RBBP5	CHD8	0.015	0.194
WDR5	CHD8	0.014	0.138
KAT14	DPY30	0.014	0.14
WDR5	MDK	0.014	0.072
HCFC2	CHD8	0.012	0.13
KAT14	HCFC2	0.01	0.152
NCOA6	CHD8	0.009	0.288
KAT2B	DPY30	0.009
TADA3	DPY30	0.008	0.332
KMT2C	CHD8	0.006	0.078
ATN1	CHD8	0.006	0.128
YEATS2	KMT2C	0.006	0.092

Related Complexes

Genename	Complexes
MBIP	huMAP3_00372.1 huMAP3_03789.1 huMAP3_07172.1 huMAP3_08451.1 huMAP3_08776.1 huMAP3_09422.1 huMAP3_09561.1 huMAP3_10027.1 huMAP3_10385.1 huMAP3_12550.1
SETD1B	huMAP3_00564.1 huMAP3_05226.1 huMAP3_07065.1 huMAP3_08776.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1
KAT14	huMAP3_00372.1 huMAP3_03789.1 huMAP3_07172.1 huMAP3_08451.1 huMAP3_08776.1 huMAP3_09422.1 huMAP3_09561.1 huMAP3_10027.1 huMAP3_10385.1 huMAP3_12550.1
TADA3	huMAP3_00372.1 huMAP3_00902.1 huMAP3_02107.1 huMAP3_07585.1 huMAP3_08451.1 huMAP3_08776.1 huMAP3_09422.1 huMAP3_09561.1 huMAP3_10027.1 huMAP3_10385.1 huMAP3_10397.1 huMAP3_12550.1
DR1	huMAP3_00047.1 huMAP3_03789.1 huMAP3_05019.1 huMAP3_07366.1 huMAP3_08451.1 huMAP3_08776.1 huMAP3_09422.1 huMAP3_09561.1 huMAP3_10027.1 huMAP3_10385.1 huMAP3_12550.1
CHD8	huMAP3_01324.1 huMAP3_03102.1 huMAP3_04001.1 huMAP3_06983.1 huMAP3_08472.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_11676.1 huMAP3_12550.1
KAT2A	huMAP3_00372.1 huMAP3_00902.1 huMAP3_03789.1 huMAP3_07585.1 huMAP3_08451.1 huMAP3_08776.1 huMAP3_09422.1 huMAP3_09561.1 huMAP3_10027.1 huMAP3_10385.1 huMAP3_10397.1 huMAP3_12550.1
KMT2D	huMAP3_07585.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1 huMAP3_12119.1 huMAP3_12373.1 huMAP3_14057.1 huMAP3_14367.1
HCFC2	huMAP3_00564.1 huMAP3_05226.1 huMAP3_07065.1 huMAP3_08776.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1
DPY30	huMAP3_00564.1 huMAP3_05226.1 huMAP3_07065.1 huMAP3_08776.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1 huMAP3_13844.1
RERE	huMAP3_00047.1 huMAP3_01287.1 huMAP3_07585.1 huMAP3_08605.1 huMAP3_08776.1 huMAP3_08800.1 huMAP3_09031.1 huMAP3_09232.1 huMAP3_09422.1 huMAP3_09513.1 huMAP3_10027.1 huMAP3_10258.1 huMAP3_10311.1 huMAP3_13482.1 huMAP3_15128.1
ZZZ3	huMAP3_00372.1 huMAP3_03789.1 huMAP3_07172.1 huMAP3_08451.1 huMAP3_08776.1 huMAP3_09422.1 huMAP3_09561.1 huMAP3_10027.1 huMAP3_10385.1 huMAP3_12550.1
KAT2B	huMAP3_00372.1 huMAP3_00902.1 huMAP3_03789.1 huMAP3_07585.1 huMAP3_08451.1 huMAP3_08776.1 huMAP3_09422.1 huMAP3_09561.1 huMAP3_10027.1 huMAP3_10385.1 huMAP3_10397.1 huMAP3_12550.1
SETD1A	huMAP3_02698.1 huMAP3_05226.1 huMAP3_07065.1 huMAP3_08776.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1
NCOA6	huMAP3_00047.1 huMAP3_05103.1 huMAP3_07585.1 huMAP3_08776.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1
KDM6A	huMAP3_00564.1 huMAP3_05226.1 huMAP3_07065.1 huMAP3_08776.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1
TADA2A	huMAP3_00372.1 huMAP3_03789.1 huMAP3_07172.1 huMAP3_08451.1 huMAP3_08776.1 huMAP3_09422.1 huMAP3_09561.1 huMAP3_10027.1 huMAP3_10385.1 huMAP3_12550.1
BOD1L1	huMAP3_00564.1 huMAP3_05226.1 huMAP3_07065.1 huMAP3_08776.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1
KMT2A	huMAP3_00564.1 huMAP3_05226.1 huMAP3_07065.1 huMAP3_08776.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1
YEATS2	huMAP3_00372.1 huMAP3_03789.1 huMAP3_07172.1 huMAP3_08451.1 huMAP3_08776.1 huMAP3_09422.1 huMAP3_09561.1 huMAP3_10027.1 huMAP3_10385.1 huMAP3_12550.1
CXXC1	huMAP3_00047.1 huMAP3_02698.1 huMAP3_07065.1 huMAP3_08776.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1
RBBP5	huMAP3_00564.1 huMAP3_05226.1 huMAP3_07065.1 huMAP3_08776.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1
KMT2C	huMAP3_00564.1 huMAP3_05226.1 huMAP3_06804.1 huMAP3_07065.1 huMAP3_08776.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1 huMAP3_12999.1
WDR5	huMAP3_00047.1 huMAP3_05103.1 huMAP3_07585.1 huMAP3_08776.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1
BOD1	huMAP3_00564.1 huMAP3_05226.1 huMAP3_07065.1 huMAP3_08776.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1 huMAP3_11792.1 huMAP3_15215.1
MDK	huMAP3_06091.1 huMAP3_08776.1 huMAP3_09361.1 huMAP3_09422.1 huMAP3_09840.1 huMAP3_10644.1
ASH2L	huMAP3_05226.1 huMAP3_06804.1 huMAP3_07065.1 huMAP3_08776.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1
ATN1	huMAP3_00047.1 huMAP3_05103.1 huMAP3_07585.1 huMAP3_08776.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_09422.1

Complex Portal: CPX-21562