hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09426.1
Complex Portal: CPX-22854
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FOXJ1 | Forkhead box protein J1 (Forkhead-related protein FKHL13) (Hepatocyte nuclear factor 3 forkhead homolog 4) (HFH-4) | 5 | UniProt NCBI |
| PEX14 | Peroxisomal membrane protein PEX14 (PTS1 receptor-docking protein) (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) | 5 | UniProt NCBI |
| RFX1 | MHC class II regulatory factor RFX1 (Enhancer factor C) (EF-C) (Regulatory factor X 1) (RFX) (Transcription factor RFX1) | 5 | UniProt NCBI |
| RFX3 | Transcription factor RFX3 (Regulatory factor X 3) | 5 | UniProt NCBI |
| MTMR4 | Myotubularin-related protein 4 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 2) (FYVE-DSP2) (Zinc finger FYVE domain-containing protein 11) | 5 | UniProt NCBI |
| CDK20 | Cyclin-dependent kinase 20 (EC 2.7.11.22) (CDK-activating kinase p42) (CAK-kinase p42) (Cell cycle-related kinase) (Cell division protein kinase 20) (Cyclin-dependent protein kinase H) (Cyclin-kinase-activating kinase p42) | 5 | UniProt NCBI |
| TBC1D32 | Protein broad-minded (TBC1 domain family member 32) | 5 | UniProt NCBI |
| RFX2 | DNA-binding protein RFX2 (Regulatory factor X 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5202 | 0.00877446561805 | 0.285714285714 | RFX3 RFX2 | Alstrom syndrome |
| HPA:0641503 | 0.0143120876465 | 0.285714285714 | RFX3 FOXJ1 | endometrium; ciliated epithelial cells[High] |
| HPA:0641502 | 0.0269093226532 | 0.285714285714 | RFX3 FOXJ1 | endometrium; ciliated epithelial cells[>=Medium] |
| HPA:0641501 | 0.0395339560282 | 0.285714285714 | RFX3 FOXJ1 | endometrium; ciliated epithelial cells[>=Low] |
| CORUM:1984 | 0.0499958217778 | 0.142857142857 | PEX14 | PEX14 homodimer complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TBC1D32 | FOXJ1 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM | ||
| FOXJ1 | RFX3 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM | ||
| RFX1 | FOXJ1 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM | ||
| CDK20 | FOXJ1 | 0.999 |
mutually_exclusive (Q9Y6A4)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM | |
| RFX2 | FOXJ1 | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM | ||
| RFX1 | RFX2 | 0.998 |
mutually_exclusive (P48380)
|
bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | |
| CDK20 | TBC1D32 | 0.997 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | ||
| RFX2 | RFX3 | 0.996 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt_WMM WMM_only | |
| RFX1 | RFX3 | 0.995 | 0.298 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only |
| PEX14 | FOXJ1 | 0.988 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM | ||
| FOXJ1 | MTMR4 | 0.985 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| RFX1 | TBC1D32 | 0.709 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | ||
| CDK20 | RFX2 | 0.68 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | ||
| TBC1D32 | RFX3 | 0.66 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | ||
| RFX2 | TBC1D32 | 0.628 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | ||
| CDK20 | RFX3 | 0.609 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | ||
| CDK20 | RFX1 | 0.555 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | ||
| PEX14 | RFX3 | 0.347 | 0.088 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | |
| CDK20 | PEX14 | 0.181 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM WMM_only | ||
| MTMR4 | RFX3 | 0.129 | 0.148 | bioplex3_WMM WMM_only | |
| TBC1D32 | MTMR4 | 0.129 | bioplex3_WMM WMM_only | ||
| PEX14 | TBC1D32 | 0.085 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | ||
| CDK20 | MTMR4 | 0.055 | bioplex3_WMM WMM_only | ||
| RFX2 | MTMR4 | 0.052 | bioplex3_WMM WMM_only | ||
| RFX1 | MTMR4 | 0.044 | 0.088 | bioplex3_WMM WMM_only | |
| PEX14 | MTMR4 | 0.019 | 0.088 | bioplex3_WMM WMM_only | |
| RFX2 | PEX14 | 0.008 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | ||
| RFX1 | PEX14 | 0.004 | 0.022 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
Related Complexes