hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09437.1
Complex Portal: CPX-18740
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MTG2 | Mitochondrial ribosome-associated GTPase 2 (GTP-binding protein 5) (Protein obg homolog 1) (ObgH1) | 5 | UniProt NCBI |
| PUS1 | Pseudouridylate synthase 1 homolog (EC 5.4.99.-) (tRNA pseudouridine synthase 1) (EC 5.4.99.12) (tRNA pseudouridine(38-40) synthase) (tRNA pseudouridylate synthase I) (tRNA-uridine isomerase I) | 5 | UniProt NCBI |
| ACSF2 | Medium-chain acyl-CoA ligase ACSF2, mitochondrial (EC 6.2.1.2) | 5 | UniProt NCBI |
| PCCA | Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCase subunit alpha) (EC 6.4.1.3) (Propanoyl-CoA:carbon dioxide ligase subunit alpha) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-77289 | 0.00573491177379 | 0.5 | ACSF2 PCCA | Mitochondrial Fatty Acid Beta-Oxidation |
| HPA:0570733 | 0.0113500251897 | 1.0 | ACSF2 PCCA MTG2 PUS1 | testis; Leydig cells[High] |
| GO:0005759 | 0.0284897407301 | 1.0 | ACSF2 PCCA MTG2 PUS1 | mitochondrial matrix |
| CORUM:7057 | 0.049938562206 | 0.25 | PCCA | Propionyl-CoA carboxylase |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MTG2 | PUS1 | 0.995 | 0.24 | bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| MTG2 | PCCA | 0.985 | 0.056 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MTG2 | ACSF2 | 0.956 | 0.13 |
structurally_consistent (dimer)
|
bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| ACSF2 | PUS1 | 0.846 | 0.084 | bioplex_WMM bioplex3_WMM WMM_only | |
| PCCA | PUS1 | 0.672 | 0.142 | bioplex_WMM bioplex3_WMM fraction boldt_WMM | |
| PCCA | ACSF2 | 0.571 | 0.086 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes