List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_09443.1

Confidence: Moderate High   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
TUBGCP3	Gamma-tubulin complex component 3 (GCP-3) (hGCP3) (Gamma-ring complex protein 104 kDa) (h104p) (hGrip104) (Spindle pole body protein Spc98 homolog) (hSpc98)	5	UniProt   NCBI
MZT2B	Mitotic-spindle organizing protein 2B (Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2B)	4	UniProt   NCBI
TUBGCP6	Gamma-tubulin complex component 6 (GCP-6)	5	UniProt   NCBI
MZT1	Mitotic-spindle organizing protein 1 (Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1)	5	UniProt   NCBI
NEDD1	Protein NEDD1 (Neural precursor cell expressed developmentally down-regulated protein 1) (NEDD-1)	5	UniProt   NCBI
TUBG2	Tubulin gamma-2 chain (Gamma-2-tubulin)	5	UniProt   NCBI
TXNDC12	Thioredoxin domain-containing protein 12 (EC 1.8.4.2) (Endoplasmic reticulum resident protein 18) (ER protein 18) (ERp18) (Endoplasmic reticulum resident protein 19) (ER protein 19) (ERp19) (Thioredoxin-like protein p19) (hTLP19)	5	UniProt   NCBI
TUBGCP4	Gamma-tubulin complex component 4 (GCP-4) (hGCP4) (Gamma-ring complex protein 76 kDa) (h76p) (hGrip76)	5	UniProt   NCBI
CFAP141	Cilia- and flagella-associated protein 141	3	UniProt   NCBI
TUBG1	Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1)	5	UniProt   NCBI
TUBGCP2	Gamma-tubulin complex component 2 (GCP-2) (hGCP2) (Gamma-ring complex protein 103 kDa) (h103p) (hGrip103) (Spindle pole body protein Spc97 homolog) (hSpc97)	5	UniProt   NCBI
MZT2A	Mitotic-spindle organizing protein 2A (Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2A)	4	UniProt   NCBI
NME7	Nucleoside diphosphate kinase homolog 7 (NDK 7) (NDP kinase homolog 7) (3'-5' exonuclease NME7) (EC 3.1.-.-) (Protein kinase NME7) (EC 2.7.-.-) (nm23-H7)	5	UniProt   NCBI
TUBGCP5	Gamma-tubulin complex component 5 (GCP-5)	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-380270	1.0135900016e-21	0.846153846154	MZT2B TUBGCP6 TUBGCP5 MZT2A TUBGCP2 TUBG2 NEDD1 MZT1 TUBGCP3 TUBGCP4 NME7	Recruitment of mitotic centrosome proteins and complexes
REAC:R-HSA-380287	1.0135900016e-21	0.846153846154	MZT2B TUBGCP6 TUBGCP5 MZT2A TUBGCP2 TUBG2 NEDD1 MZT1 TUBGCP3 TUBGCP4 NME7	Centrosome maturation
REAC:R-HSA-380320	5.41304293817e-21	0.846153846154	MZT2B TUBGCP6 TUBGCP5 MZT2A TUBGCP2 TUBG2 NEDD1 MZT1 TUBGCP3 TUBGCP4 NME7	Recruitment of NuMA to mitotic centrosomes
GO:0000930	1.03716537278e-20	0.692307692308	MZT2B TUBGCP4 TUBGCP5 MZT2A TUBGCP2 TUBG2 TUBGCP6 TUBGCP3 MZT1	gamma-tubulin complex
REAC:R-HSA-69275	2.63022280444e-17	0.846153846154	MZT2B TUBGCP6 TUBGCP5 MZT2A TUBGCP2 TUBG2 NEDD1 MZT1 TUBGCP3 TUBGCP4 NME7	G2/M Transition
REAC:R-HSA-453274	2.96171795197e-17	0.846153846154	MZT2B TUBGCP6 TUBGCP5 MZT2A TUBGCP2 TUBG2 NEDD1 MZT1 TUBGCP3 TUBGCP4 NME7	Mitotic G2-G2/M phases
REAC:R-HSA-68877	3.74109824231e-17	0.846153846154	MZT2B TUBGCP6 TUBGCP5 MZT2A TUBGCP2 TUBG2 NEDD1 MZT1 TUBGCP3 TUBGCP4 NME7	Mitotic Prometaphase
CORUM:6893	1.302095624e-14	0.384615384615	TUBGCP5 TUBGCP6 TUBGCP2 TUBGCP3 TUBGCP4	Gamma-tubulin complex
REAC:R-HSA-68886	7.92958489798e-14	0.846153846154	MZT2B TUBGCP6 TUBGCP5 MZT2A TUBGCP2 TUBG2 NEDD1 MZT1 TUBGCP3 TUBGCP4 NME7	M Phase
GO:0000931	1.77530865968e-13	0.461538461538	MZT2B TUBGCP4 MZT2A TUBGCP5 TUBGCP6 MZT1	gamma-tubulin ring complex
GO:0007020	2.18923165022e-13	0.615384615385	TUBGCP6 TUBGCP4 TUBGCP5 TUBGCP2 TUBG2 NEDD1 MZT1 TUBGCP3	microtubule nucleation
REAC:R-HSA-69278	2.36618758562e-12	0.846153846154	MZT2B TUBGCP6 TUBGCP5 MZT2A TUBGCP2 TUBG2 NEDD1 MZT1 TUBGCP3 TUBGCP4 NME7	Cell Cycle, Mitotic
WP:WP4940	3.40538907118e-12	0.384615384615	TUBGCP5 TUBGCP6 TUBGCP2 TUBGCP3 TUBGCP4	15q11 2 copy number variation syndrome
GO:0000923	1.15886510536e-11	0.384615384615	TUBGCP5 TUBGCP6 TUBGCP2 TUBGCP3 TUBGCP4	equatorial microtubule organizing center
REAC:R-HSA-1640170	2.3168987326e-11	0.846153846154	MZT2B TUBGCP6 TUBGCP5 MZT2A TUBGCP2 TUBG2 NEDD1 MZT1 TUBGCP3 TUBGCP4 NME7	Cell Cycle
GO:0046785	3.92840459485e-11	0.615384615385	TUBGCP6 TUBGCP4 TUBGCP5 TUBGCP2 TUBG2 NEDD1 MZT1 TUBGCP3	microtubule polymerization
GO:0031109	5.75263901549e-10	0.615384615385	TUBGCP6 TUBGCP4 TUBGCP5 TUBGCP2 TUBG2 NEDD1 MZT1 TUBGCP3	microtubule polymerization or depolymerization
GO:0005813	6.02706508442e-10	0.846153846154	MZT2B TUBGCP6 TUBGCP5 MZT2A TUBGCP2 TUBG2 NEDD1 MZT1 TUBGCP3 TUBGCP4 NME7	centrosome
GO:0043015	1.11506446951e-09	0.461538461538	TUBGCP6 TUBGCP4 TUBGCP5 TUBGCP3 TUBGCP2 NEDD1	gamma-tubulin binding
GO:0005815	3.89304555858e-09	0.846153846154	MZT2B TUBGCP6 TUBGCP5 MZT2A TUBGCP2 TUBG2 NEDD1 MZT1 TUBGCP3 TUBGCP4 NME7	microtubule organizing center
GO:0015630	7.12775108731e-09	0.923076923077	MZT2B TUBGCP6 TUBGCP5 MZT2A TUBGCP2 CFAP141 TUBG2 NEDD1 MZT1 TUBGCP3 TUBGCP4 NME7	microtubule cytoskeleton
GO:0051011	9.14893106478e-09	0.384615384615	TUBGCP5 TUBGCP6 TUBGCP2 TUBGCP3 TUBGCP4	microtubule minus-end binding
GO:0051258	6.48840857751e-08	0.615384615385	TUBGCP6 TUBGCP4 TUBGCP5 TUBGCP2 TUBG2 NEDD1 MZT1 TUBGCP3	protein polymerization
WP:WP3998	7.58601608184e-07	0.384615384615	TUBGCP5 TUBGCP6 TUBGCP2 TUBGCP3 TUBGCP4	Prader Willi and Angelman syndrome
GO:0005856	9.4194626634e-07	0.923076923077	MZT2B TUBGCP6 TUBGCP5 MZT2A TUBGCP2 CFAP141 TUBG2 NEDD1 MZT1 TUBGCP3 TUBGCP4 NME7	cytoskeleton
GO:0007051	1.46473372996e-06	0.538461538462	TUBGCP6 TUBGCP4 TUBGCP5 TUBG2 TUBGCP3 TUBGCP2 MZT1	spindle organization
GO:0051225	8.21345853885e-06	0.461538461538	TUBGCP6 TUBGCP4 TUBGCP5 TUBGCP3 TUBGCP2 MZT1	spindle assembly
GO:0031122	1.23631381704e-05	0.384615384615	TUBGCP5 TUBGCP6 TUBGCP2 TUBGCP3 TUBGCP4	cytoplasmic microtubule organization
GO:0032153	2.40539223582e-05	0.384615384615	TUBGCP5 TUBGCP6 TUBGCP2 TUBGCP3 TUBGCP4	cell division site
GO:0000226	8.78946407719e-05	0.615384615385	TUBGCP6 TUBGCP4 TUBGCP5 TUBGCP2 TUBG2 NEDD1 MZT1 TUBGCP3	microtubule cytoskeleton organization
GO:0051321	0.000108334258294	0.461538461538	TUBGCP6 TUBGCP4 TUBG2 TUBGCP5 TUBGCP3 TUBGCP2	meiotic cell cycle
CORUM:3714	0.00012303818858	0.153846153846	TUBGCP2 TUBGCP3	Pericentrin-GCP complex
GO:0007059	0.00018481895738	0.538461538462	TUBGCP6 TUBGCP4 TUBGCP5 TUBG2 TUBGCP3 TUBGCP2 MZT1	chromosome segregation
GO:0097435	0.000441123490352	0.615384615385	TUBGCP6 TUBGCP4 TUBGCP5 TUBGCP2 TUBG2 NEDD1 MZT1 TUBGCP3	supramolecular fiber organization
GO:0007017	0.00129353095932	0.615384615385	TUBGCP6 TUBGCP4 TUBGCP5 TUBGCP2 TUBG2 NEDD1 MZT1 TUBGCP3	microtubule-based process
GO:0000278	0.00178123579601	0.615384615385	TUBGCP6 TUBGCP4 TUBGCP5 TUBGCP2 TUBG2 NEDD1 MZT1 TUBGCP3	mitotic cell cycle
GO:0015631	0.00499598235053	0.461538461538	TUBGCP6 TUBGCP4 TUBGCP5 TUBGCP3 TUBGCP2 NEDD1	tubulin binding
GO:0005819	0.00562688830749	0.461538461538	MZT2B MZT2A TUBG2 NEDD1 MZT1 TUBGCP3	spindle
GO:0140694	0.00656917456467	0.461538461538	TUBGCP6 TUBGCP4 TUBGCP5 TUBGCP3 TUBGCP2 MZT1	non-membrane-bounded organelle assembly
HPA:0460661	0.015986682941	0.846153846154	MZT2B TUBGCP6 TUBGCP5 MZT2A TUBGCP2 TUBG2 NEDD1 MZT1 TUBGCP3 TUBGCP4 NME7	skin 1; keratinocytes[>=Low]
GO:0008017	0.0334216999074	0.384615384615	TUBGCP5 TUBGCP6 TUBGCP2 TUBGCP3 TUBGCP4	microtubule binding
HPA:0330222	0.0355848887156	0.769230769231	MZT2B TUBGCP4 TUBGCP5 MZT2A TUBGCP2 TUBG2 NEDD1 MZT1 TUBGCP3 NME7	oral mucosa; squamous epithelial cells[>=Medium]
GO:0043228	0.0357486336252	0.923076923077	MZT2B TUBGCP6 TUBGCP5 MZT2A TUBGCP2 CFAP141 TUBG2 NEDD1 MZT1 TUBGCP3 TUBGCP4 NME7	non-membrane-bounded organelle
GO:0043232	0.0357486336252	0.923076923077	MZT2B TUBGCP6 TUBGCP5 MZT2A TUBGCP2 CFAP141 TUBG2 NEDD1 MZT1 TUBGCP3 TUBGCP4 NME7	intracellular non-membrane-bounded organelle
HPA:0470681	0.0420352325757	0.846153846154	MZT2B TUBGCP6 TUBGCP5 MZT2A TUBGCP2 TUBG2 NEDD1 MZT1 TUBGCP3 TUBGCP4 NME7	skin 2; epidermal cells[>=Low]
GO:0007010	0.0465632527412	0.615384615385	TUBGCP6 TUBGCP4 TUBGCP5 TUBGCP2 TUBG2 NEDD1 MZT1 TUBGCP3	cytoskeleton organization



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?
TUBGCP2	TUBGCP5	1.0	0.264
TUBG1	TUBGCP5	1.0	0.208
TUBGCP3	TUBGCP5	1.0	0.19
TUBGCP6	TUBGCP5	1.0	0.258
TUBGCP4	TUBGCP5	1.0	0.06
TUBGCP3	MZT1	1.0	0.204
TUBGCP5	MZT2A	1.0	0.072
MZT2B	TUBGCP6	1.0	0.092
TUBGCP2	TUBGCP6	1.0	0.156
TUBGCP4	TUBGCP6	1.0	0.148
NME7	TUBGCP5	1.0	0.112
MZT2B	TUBGCP2	1.0	0.604
TUBGCP2	NME7	1.0	0.082
MZT2B	TUBG1	1.0	0.738
TUBG2	TUBG1	1.0
TUBG1	MZT2A	1.0	0.084
TUBGCP6	MZT2A	0.999	0.168
TUBGCP4	MZT2A	0.999	0.108
TUBGCP3	TUBGCP6	0.999	0.098
TUBGCP3	MZT2A	0.999	0.092
TUBG2	TUBGCP5	0.999
MZT2B	TUBGCP5	0.999	0.148
TUBGCP2	MZT2A	0.999	0.072
NME7	TUBGCP6	0.999	0.086
MZT2B	MZT2A	0.999	0.072
TUBG1	TUBGCP6	0.999	0.152
TUBG2	TUBGCP2	0.999
TUBG2	TUBGCP6	0.999
TUBGCP4	TUBG1	0.999	0.346
TUBGCP3	TUBG2	0.999
NME7	MZT2A	0.999	0.162
TUBGCP4	NME7	0.999	0.114
TUBGCP3	NME7	0.999	0.068
TUBGCP3	MZT2B	0.999	0.22
MZT2B	TUBG2	0.999
TUBGCP3	TUBGCP2	0.999	0.684
TUBG2	MZT2A	0.999
MZT1	TUBG1	0.999	0.192
TUBG2	TUBGCP4	0.999
MZT2B	TUBGCP4	0.999	0.302
MZT2B	NME7	0.999	0.034
MZT1	NEDD1	0.999	0.08
TUBGCP3	TUBGCP4	0.999	0.108
MZT1	TUBGCP6	0.998	0.152
MZT1	TUBGCP4	0.998	0.112
TUBG1	NME7	0.998	0.03
MZT1	TUBGCP5	0.998	0.184
TUBGCP4	TUBGCP2	0.998	0.266
TUBGCP3	TUBG1	0.998	0.64
NEDD1	TUBGCP2	0.998	0.08
MZT1	TUBGCP2	0.998	0.214
MZT2B	MZT1	0.998	0.114
TUBG2	NME7	0.998
MZT1	MZT2A	0.998	0.1
TUBG1	TUBGCP2	0.998	0.93
NEDD1	TUBGCP6	0.997	0.1
MZT1	NME7	0.997	0.074
NEDD1	TUBGCP5	0.997	0.084
MZT2B	NEDD1	0.997	0.04
NEDD1	TUBGCP4	0.994	0.108
TUBGCP3	NEDD1	0.993	0.182
NEDD1	TUBG1	0.986	0.134
TXNDC12	MZT2A	0.983	0.06
NEDD1	MZT2A	0.983	0.098
TUBGCP6	TXNDC12	0.98	0.074
NEDD1	NME7	0.979	0.042
TXNDC12	TUBGCP5	0.963	0.082
CFAP141	NME7	0.953
MZT2B	TXNDC12	0.926	0.06
TUBG1	TXNDC12	0.922	0.12
TUBGCP4	TXNDC12	0.904	0.03
TUBGCP3	TXNDC12	0.898	0.034
TUBGCP2	TXNDC12	0.887	0.032
NME7	TXNDC12	0.824	0.05
MZT1	TUBG2	0.502
NEDD1	TUBG2	0.143
NEDD1	TXNDC12	0.029	0.026
CFAP141	TUBG1	0.017





Related Complexes

Genename	Complexes
TUBGCP3	huMAP3_00522.1 huMAP3_09443.1 huMAP3_14882.1
MZT2B	huMAP3_00522.1 huMAP3_09443.1 huMAP3_10467.1 huMAP3_14882.1
TUBGCP6	huMAP3_01758.1 huMAP3_09443.1 huMAP3_14882.1
MZT1	huMAP3_00522.1 huMAP3_09443.1 huMAP3_14882.1
NEDD1	huMAP3_00522.1 huMAP3_09443.1 huMAP3_11190.1 huMAP3_14584.1 huMAP3_14882.1
TUBG2	huMAP3_00522.1 huMAP3_09443.1 huMAP3_14882.1
TXNDC12	huMAP3_01758.1 huMAP3_03304.1 huMAP3_09443.1 huMAP3_11976.1 huMAP3_14882.1 huMAP3_14900.1
TUBGCP4	huMAP3_00522.1 huMAP3_09443.1 huMAP3_14882.1
CFAP141	huMAP3_00522.1 huMAP3_01284.1 huMAP3_09443.1 huMAP3_09578.1 huMAP3_11571.1 huMAP3_11862.1 huMAP3_11880.1 huMAP3_12530.1 huMAP3_12972.1 huMAP3_14883.1
TUBG1	huMAP3_00522.1 huMAP3_09443.1 huMAP3_14584.1 huMAP3_14882.1
TUBGCP2	huMAP3_00522.1 huMAP3_09443.1 huMAP3_14882.1
MZT2A	huMAP3_01758.1 huMAP3_09443.1 huMAP3_14882.1
NME7	huMAP3_00522.1 huMAP3_01284.1 huMAP3_09443.1 huMAP3_09578.1 huMAP3_12630.1 huMAP3_14882.1
TUBGCP5	huMAP3_01758.1 huMAP3_09443.1 huMAP3_14882.1