hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09452.1
Complex Portal: CPX-9182
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| AFG2A | ATPase family gene 2 protein homolog A (EC 3.6.4.10) (AFG2 AAA ATPase homolog A) (Ribosome biogenesis protein SPATA5) (Spermatogenesis-associated factor protein) (Spermatogenesis-associated protein 5) | 5 | UniProt NCBI |
| AIRIM | AFG2-interacting ribosome maturation factor (Ribosome biogenesis protein C1orf109) | 5 | UniProt NCBI |
| CINP | Cyclin-dependent kinase 2-interacting protein (CDK2-interacting protein) | 5 | UniProt NCBI |
| AFG2B | ATPase family gene 2 protein homolog B (EC 3.6.4.10) (AFG2 AAA ATPase homolog B) (Ribosome biogenesis protein SPATA5L1) (Spermatogenesis-associated protein 5-like protein 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:1990275 | 2.15253635486e-05 | 0.75 | AFG2A AFG2B CINP | preribosome binding |
| GO:0042273 | 2.70701716559e-05 | 1.0 | AFG2A AFG2B AIRIM CINP | ribosomal large subunit biogenesis |
| GO:0042254 | 0.0044563729956 | 1.0 | AFG2A AFG2B AIRIM CINP | ribosome biogenesis |
| GO:0022613 | 0.0254935353828 | 1.0 | AFG2A AFG2B AIRIM CINP | ribonucleoprotein complex biogenesis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CINP | AFG2B | 1.0 | 0.17 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM | |
| CINP | AFG2A | 1.0 | 0.27 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM | |
| CINP | AIRIM | 0.999 | 0.274 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM | |
| AIRIM | AFG2B | 0.999 | 0.094 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM |
| AFG2B | AFG2A | 0.997 | 0.256 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 boldt_WMM |
| AIRIM | AFG2A | 0.751 | 0.176 |
structurally_consistent (Q9BVQ7)
|
bioplex_WMM bioplex3_WMM WMM_only boldt_WMM |
Related Complexes