hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09478.1
Complex Portal: CPX-25426
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SCO2 | Protein SCO2 homolog, mitochondrial | 5 | UniProt NCBI |
| NUBPL | Iron-sulfur cluster transfer protein NUBPL (IND1 homolog) (Nucleotide-binding protein-like) (huInd1) | 5 | UniProt NCBI |
| NUBP2 | Cytosolic Fe-S cluster assembly factor NUBP2 (Nucleotide-binding protein 2) (NBP 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0003542 | 0.0167410266547 | 0.666666666667 | SCO2 NUBPL | Increased serum pyruvate |
| HP:0004366 | 0.0167410266547 | 0.666666666667 | SCO2 NUBPL | Abnormality of glycolysis |
| HP:0011013 | 0.0278951902268 | 0.666666666667 | SCO2 NUBPL | Abnormal circulating carbohydrate concentration |
| REAC:R-HSA-611105 | 0.0329299631783 | 0.666666666667 | SCO2 NUBPL | Respiratory electron transport |
| REAC:R-HSA-163200 | 0.049233254294 | 0.666666666667 | SCO2 NUBPL | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| NUBPL | NUBP2 | 0.991 | 0.08 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SCO2 | NUBP2 | 0.955 | 0.0500909090909 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 boldt_WMM WMM_only | |
| NUBPL | SCO2 | 0.019 | 0.07 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes