hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09505.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ATP6V0A1 | V-type proton ATPase 116 kDa subunit a 1 (V-ATPase 116 kDa subunit a 1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1) | 5 | UniProt NCBI |
| ATP6V0D1 | V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (32 kDa accessory protein) (V-ATPase 40 kDa accessory protein) (V-ATPase AC39 subunit) (p39) (Vacuolar proton pump subunit d 1) | 5 | UniProt NCBI |
| ATP6AP2 | Renin receptor (ATPase H(+)-transporting lysosomal accessory protein 2) (ATPase H(+)-transporting lysosomal-interacting protein 2) (ER-localized type I transmembrane adapter) (Embryonic liver differentiation factor 10) (N14F) (Renin/prorenin receptor) (Vacuolar ATP synthase membrane sector-associated protein M8-9) (ATP6M8-9) (V-ATPase M8.9 subunit) [Cleaved into: Renin receptor N-terminal fragment; Renin receptor C-terminal fragment] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0000220 | 3.84480164306e-07 | 1.0 | ATP6V0D1 ATP6V0A1 ATP6AP2 | vacuolar proton-transporting V-type ATPase, V0 domain |
| GO:0033179 | 3.84480164306e-07 | 1.0 | ATP6V0D1 ATP6V0A1 ATP6AP2 | proton-transporting V-type ATPase, V0 domain |
| GO:0033177 | 2.11464090368e-05 | 1.0 | ATP6V0D1 ATP6V0A1 ATP6AP2 | proton-transporting two-sector ATPase complex, proton-transporting domain |
| GO:0016471 | 0.000148024863258 | 1.0 | ATP6V0D1 ATP6V0A1 ATP6AP2 | vacuolar proton-transporting V-type ATPase complex |
| GO:0033176 | 0.000170228592746 | 1.0 | ATP6V0D1 ATP6V0A1 ATP6AP2 | proton-transporting V-type ATPase complex |
| KEGG:04966 | 0.000192947765955 | 0.666666666667 | ATP6V0D1 ATP6V0A1 | Collecting duct acid secretion |
| GO:0007035 | 0.000314889254566 | 1.0 | ATP6V0D1 ATP6V0A1 ATP6AP2 | vacuolar acidification |
| KEGG:05110 | 0.000754254484718 | 0.666666666667 | ATP6V0D1 ATP6V0A1 | Vibrio cholerae infection |
| GO:0051452 | 0.00102463963787 | 1.0 | ATP6V0D1 ATP6V0A1 ATP6AP2 | intracellular pH reduction |
| GO:0016469 | 0.00127301382402 | 1.0 | ATP6V0D1 ATP6V0A1 ATP6AP2 | proton-transporting two-sector ATPase complex |
| KEGG:04721 | 0.00134759096089 | 0.666666666667 | ATP6V0D1 ATP6V0A1 | Synaptic vesicle cycle |
| KEGG:05120 | 0.0014867141158 | 0.666666666667 | ATP6V0D1 ATP6V0A1 | Epithelial cell signaling in Helicobacter pylori infection |
| KEGG:05323 | 0.00173372250929 | 0.666666666667 | ATP6V0D1 ATP6V0A1 | Rheumatoid arthritis |
| GO:1902600 | 0.00252170927764 | 1.0 | ATP6V0D1 ATP6V0A1 ATP6AP2 | proton transmembrane transport |
| REAC:R-HSA-77387 | 0.00257431960226 | 0.666666666667 | ATP6V0D1 ATP6V0A1 | Insulin receptor recycling |
| REAC:R-HSA-917977 | 0.00257431960226 | 0.666666666667 | ATP6V0D1 ATP6V0A1 | Transferrin endocytosis and recycling |
| REAC:R-HSA-1222556 | 0.00316638779295 | 0.666666666667 | ATP6V0D1 ATP6V0A1 | ROS and RNS production in phagocytes |
| GO:0051453 | 0.00328922780564 | 1.0 | ATP6V0D1 ATP6V0A1 ATP6AP2 | regulation of intracellular pH |
| GO:0030641 | 0.00363525995351 | 1.0 | ATP6V0D1 ATP6V0A1 ATP6AP2 | regulation of cellular pH |
| GO:0006885 | 0.00419852339422 | 1.0 | ATP6V0D1 ATP6V0A1 ATP6AP2 | regulation of pH |
| KEGG:00190 | 0.0056035932516 | 0.666666666667 | ATP6V0D1 ATP6V0A1 | Oxidative phosphorylation |
| KEGG:04142 | 0.00569595332742 | 0.666666666667 | ATP6V0D1 ATP6V0A1 | Lysosome |
| KEGG:04145 | 0.00656095956975 | 0.666666666667 | ATP6V0D1 ATP6V0A1 | Phagosome |
| KEGG:05152 | 0.00802719593767 | 0.666666666667 | ATP6V0D1 ATP6V0A1 | Tuberculosis |
| REAC:R-HSA-917937 | 0.00902065028483 | 0.666666666667 | ATP6V0D1 ATP6V0A1 | Iron uptake and transport |
| REAC:R-HSA-74752 | 0.0128584085686 | 0.666666666667 | ATP6V0D1 ATP6V0A1 | Signaling by Insulin receptor |
| KEGG:05165 | 0.0324411425615 | 0.666666666667 | ATP6V0D1 ATP6V0A1 | Human papillomavirus infection |
| GO:1904949 | 0.042099520671 | 1.0 | ATP6V0D1 ATP6V0A1 ATP6AP2 | ATPase complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ATP6V0A1 | ATP6V0D1 | 1.0 | 0.412 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM bioplex3_HCT116 fraction |
| ATP6V0A1 | ATP6AP2 | 0.998 | 0.078 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 gupta_WMM |
| ATP6V0D1 | ATP6AP2 | 0.991 | 0.194 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 |
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