hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09533.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FMC1 | Protein FMC1 homolog (ATP synthase assembly factor FMC1, mitochondrial) (Formation of mitochondrial complex V assembly factor 1 homolog) | 4 | UniProt NCBI |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 (ATP12 homolog) | 5 | UniProt NCBI |
| HMGCL | Hydroxymethylglutaryl-CoA lyase, mitochondrial (HL) (HMG-CoA lyase) (EC 4.1.3.4) (3-hydroxy-3-methylglutarate-CoA lyase) | 5 | UniProt NCBI |
| SPG21 | Maspardin (Acid cluster protein 33) (Spastic paraplegia 21 autosomal recessive Mast syndrome protein) (Spastic paraplegia 21 protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0570762 | 0.0115490191121 | 1.0 | ATPAF2 SPG21 FMC1 HMGCL | testis; pachytene spermatocytes[>=Medium] |
| HPA:0060841 | 0.0162383601895 | 0.75 | ATPAF2 FMC1 SPG21 | bronchus; basal cells[>=Low] |
| HPA:0210852 | 0.0184264477946 | 0.75 | ATPAF2 FMC1 SPG21 | fallopian tube; ciliated cells (cell body)[>=Medium] |
| HPA:0570761 | 0.0273327385677 | 1.0 | ATPAF2 SPG21 FMC1 HMGCL | testis; pachytene spermatocytes[>=Low] |
| HP:0034353 | 0.0305087012549 | 0.75 | ATPAF2 SPG21 HMGCL | Appendicular spasticity |
| HPA:0060852 | 0.0439037308887 | 0.75 | ATPAF2 FMC1 SPG21 | bronchus; ciliated cells (cell body)[>=Medium] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ATPAF2 | FMC1 | 1.0 | 0.568 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction |
| SPG21 | ATPAF2 | 0.997 | 0.042 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| HMGCL | ATPAF2 | 0.973 | 0.098 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| SPG21 | FMC1 | 0.732 | 0.06 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes