hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_09536.1
Complex Portal: CPX-11950
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| BIRC2 | Baculoviral IAP repeat-containing protein 2 (EC 2.3.2.27) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (RING-type E3 ubiquitin transferase BIRC2) (TNFR2-TRAF-signaling complex protein 2) | 5 | UniProt NCBI |
| CXCL1 | Growth-regulated alpha protein (C-X-C motif chemokine 1) (GRO-alpha(1-73)) (Melanoma growth stimulatory activity) (MGSA) (Neutrophil-activating protein 3) (NAP-3) [Cleaved into: GRO-alpha(4-73); GRO-alpha(5-73); GRO-alpha(6-73)] | 5 | UniProt NCBI |
| BIRC3 | Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1) | 5 | UniProt NCBI |
| HTRA2 | Serine protease HTRA2, mitochondrial (EC 3.4.21.108) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine protease 25) (Serine proteinase OMI) | 5 | UniProt NCBI |
| DIABLO | Diablo IAP-binding mitochondrial protein (Diablo homolog, mitochondrial) (Direct IAP-binding protein with low pI) (Second mitochondria-derived activator of caspase) (Smac) [Cleaved into: Diablo IAP-binding mitochondrial protein, cleaved form] | 5 | UniProt NCBI |
| TANK | TRAF family member-associated NF-kappa-B activator (TRAF-interacting protein) (I-TRAF) | 5 | UniProt NCBI |
| TRAF2 | TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3) | 5 | UniProt NCBI |
| TBK1 | Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1) | 5 | UniProt NCBI |
| TRAF1 | TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6) | 5 | UniProt NCBI |
| IKBKE | Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP231 | 1.86966962117e-12 | 0.7 | TBK1 DIABLO TRAF1 TANK BIRC3 BIRC2 TRAF2 | TNF alpha signaling pathway |
| REAC:R-HSA-5357905 | 2.6246608021e-11 | 0.6 | TRAF1 IKBKE BIRC3 TBK1 BIRC2 TRAF2 | Regulation of TNFR1 signaling |
| KEGG:04621 | 5.06287201616e-11 | 0.7 | TBK1 IKBKE TANK CXCL1 BIRC2 TRAF2 BIRC3 | NOD-like receptor signaling pathway |
| REAC:R-HSA-75893 | 8.51787906811e-11 | 0.6 | TRAF1 IKBKE BIRC3 TBK1 BIRC2 TRAF2 | TNF signaling |
| REAC:R-HSA-5357786 | 4.6340384772e-10 | 0.5 | BIRC2 IKBKE BIRC3 TBK1 TRAF2 | TNFR1-induced proapoptotic signaling |
| REAC:R-HSA-168164 | 2.45110246917e-09 | 0.6 | IKBKE TBK1 TANK BIRC3 BIRC2 TRAF2 | Toll Like Receptor 3 (TLR3) Cascade |
| KEGG:04210 | 2.78091592761e-09 | 0.6 | TRAF1 DIABLO HTRA2 BIRC3 BIRC2 TRAF2 | Apoptosis |
| REAC:R-HSA-937061 | 2.8016230658e-09 | 0.6 | IKBKE TBK1 TANK BIRC3 BIRC2 TRAF2 | TRIF(TICAM1)-mediated TLR4 signaling |
| REAC:R-HSA-166166 | 2.8016230658e-09 | 0.6 | IKBKE TBK1 TANK BIRC3 BIRC2 TRAF2 | MyD88-independent TLR4 cascade |
| GO:0071345 | 7.732208047e-09 | 0.9 | TBK1 TRAF1 IKBKE TANK HTRA2 CXCL1 BIRC2 TRAF2 BIRC3 | cellular response to cytokine stimulus |
| REAC:R-HSA-166016 | 1.55084226963e-08 | 0.6 | IKBKE TBK1 TANK BIRC3 BIRC2 TRAF2 | Toll Like Receptor 4 (TLR4) Cascade |
| REAC:R-HSA-73887 | 1.8848100577e-08 | 0.6 | TRAF1 IKBKE BIRC3 TBK1 BIRC2 TRAF2 | Death Receptor Signaling |
| GO:0034097 | 2.24523453502e-08 | 0.9 | TBK1 TRAF1 IKBKE TANK HTRA2 CXCL1 BIRC2 TRAF2 BIRC3 | response to cytokine |
| REAC:R-HSA-168898 | 3.7171214705e-08 | 0.6 | IKBKE TBK1 TANK BIRC3 BIRC2 TRAF2 | Toll-like Receptor Cascades |
| KEGG:04064 | 5.37690461794e-08 | 0.5 | TRAF1 BIRC2 TRAF2 CXCL1 BIRC3 | NF-kappa B signaling pathway |
| WP:WP254 | 6.58010695697e-08 | 0.5 | TRAF1 BIRC2 TRAF2 BIRC3 DIABLO | Apoptosis |
| KEGG:04668 | 1.29036955539e-07 | 0.5 | TRAF1 BIRC2 TRAF2 CXCL1 BIRC3 | TNF signaling pathway |
| KEGG:04215 | 1.31083166186e-07 | 0.4 | BIRC2 BIRC3 DIABLO HTRA2 | Apoptosis - multiple species |
| GO:0019221 | 1.34405443166e-07 | 0.8 | TBK1 TRAF1 IKBKE TANK CXCL1 BIRC2 TRAF2 BIRC3 | cytokine-mediated signaling pathway |
| REAC:R-HSA-933541 | 6.28819246487e-07 | 0.4 | TBK1 IKBKE TANK TRAF2 | TRAF6 mediated IRF7 activation |
| WP:WP2036 | 6.34019510892e-07 | 0.4 | TRAF1 BIRC2 BIRC3 TRAF2 | TNF related weak inducer of apoptosis TWEAK signaling pathway |
| GO:0043122 | 7.31823921372e-07 | 0.7 | TRAF1 TBK1 IKBKE TANK BIRC3 BIRC2 TRAF2 | regulation of canonical NF-kappaB signal transduction |
| CORUM:5212 | 9.41265768188e-07 | 0.3 | TBK1 TANK TRAF2 | Kinase maturation complex 2 |
| REAC:R-HSA-5357956 | 9.51119385451e-07 | 0.4 | TRAF1 BIRC2 BIRC3 TRAF2 | TNFR1-induced NF-kappa-B signaling pathway |
| GO:0007249 | 1.50858883682e-06 | 0.7 | TRAF1 TBK1 IKBKE TANK BIRC3 BIRC2 TRAF2 | canonical NF-kappaB signal transduction |
| GO:0035631 | 1.81927560642e-06 | 0.4 | BIRC2 TRAF2 HTRA2 DIABLO | CD40 receptor complex |
| WP:WP5039 | 2.89862310315e-06 | 0.4 | TBK1 TRAF2 CXCL1 TANK | SARS CoV 2 innate immunity evasion and cell specific immune response |
| KEGG:05417 | 3.23580203705e-06 | 0.5 | TBK1 IKBKE TRAF2 CXCL1 TANK | Lipid and atherosclerosis |
| WP:WP3865 | 3.3838359376e-06 | 0.4 | TBK1 IKBKE TANK TRAF2 | Novel intracellular components of RIG I like receptor pathway |
| KEGG:04622 | 3.69260422052e-06 | 0.4 | TBK1 IKBKE TANK TRAF2 | RIG-I-like receptor signaling pathway |
| KEGG:04657 | 7.35168986601e-06 | 0.4 | TBK1 IKBKE CXCL1 TRAF2 | IL-17 signaling pathway |
| REAC:R-HSA-5676594 | 9.16769422079e-06 | 0.3 | BIRC2 BIRC3 TRAF2 | TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway |
| KEGG:05222 | 1.15020714318e-05 | 0.4 | TRAF1 BIRC2 BIRC3 TRAF2 | Small cell lung cancer |
| REAC:R-HSA-9013973 | 1.22191993529e-05 | 0.3 | TBK1 TANK IKBKE | TICAM1-dependent activation of IRF3/IRF7 |
| WP:WP1772 | 1.51423209535e-05 | 0.4 | BIRC2 BIRC3 DIABLO HTRA2 | Apoptosis modulation and signaling |
| REAC:R-HSA-936964 | 2.02026912702e-05 | 0.3 | TBK1 TANK IKBKE | Activation of IRF3, IRF7 mediated by TBK1, IKBKE |
| GO:0007166 | 2.41848815393e-05 | 1.0 | TBK1 DIABLO TRAF1 IKBKE TANK HTRA2 CXCL1 BIRC2 TRAF2 BIRC3 | cell surface receptor signaling pathway |
| WP:WP4658 | 2.5825431588e-05 | 0.4 | TRAF1 BIRC2 BIRC3 TRAF2 | Small cell lung cancer |
| CORUM:5529 | 3.07577115383e-05 | 0.2 | BIRC2 TRAF2 | TRAF2-cIAP1/BIRC2 complex |
| REAC:R-HSA-168928 | 3.1695922856e-05 | 0.4 | TBK1 IKBKE TANK TRAF2 | DDX58/IFIH1-mediated induction of interferon-alpha/beta |
| GO:0071310 | 3.33907936372e-05 | 0.9 | TBK1 TRAF1 IKBKE TANK HTRA2 CXCL1 BIRC2 TRAF2 BIRC3 | cellular response to organic substance |
| GO:0035556 | 4.06121935084e-05 | 1.0 | TBK1 DIABLO TRAF1 IKBKE TANK HTRA2 CXCL1 BIRC2 TRAF2 BIRC3 | intracellular signal transduction |
| REAC:R-HSA-168249 | 7.36603442032e-05 | 0.7 | TBK1 IKBKE TANK CXCL1 BIRC2 TRAF2 BIRC3 | Innate Immune System |
| CORUM:5210 | 9.22394575203e-05 | 0.2 | TANK TRAF2 | TANK-TRAF2-TRAF3 complex |
| CORUM:5531 | 9.22394575203e-05 | 0.2 | BIRC2 TRAF2 | Tumor necrosis factor receptor 1 signaling complex |
| KEGG:05168 | 0.000111151832678 | 0.5 | BIRC2 IKBKE BIRC3 TBK1 TRAF2 | Herpes simplex virus 1 infection |
| KEGG:05167 | 0.000168793450641 | 0.4 | TBK1 IKBKE CXCL1 TRAF2 | Kaposi sarcoma-associated herpesvirus infection |
| REAC:R-HSA-5675482 | 0.000224045063065 | 0.3 | BIRC2 BIRC3 TRAF2 | Regulation of necroptotic cell death |
| REAC:R-HSA-5213460 | 0.000224045063065 | 0.3 | BIRC2 BIRC3 TRAF2 | RIPK1-mediated regulated necrosis |
| GO:0010033 | 0.000284504284319 | 0.9 | TBK1 TRAF1 IKBKE TANK HTRA2 CXCL1 BIRC2 TRAF2 BIRC3 | response to organic substance |
| GO:0071356 | 0.000602766582881 | 0.5 | TRAF1 BIRC2 TRAF2 BIRC3 TANK | cellular response to tumor necrosis factor |
| GO:0070887 | 0.000805875475181 | 0.9 | TBK1 TRAF1 IKBKE TANK HTRA2 CXCL1 BIRC2 TRAF2 BIRC3 | cellular response to chemical stimulus |
| GO:0009898 | 0.000943475289248 | 0.5 | TRAF1 BIRC2 TRAF2 HTRA2 DIABLO | cytoplasmic side of plasma membrane |
| GO:0034612 | 0.00104888708432 | 0.5 | TRAF1 BIRC2 TRAF2 BIRC3 TANK | response to tumor necrosis factor |
| WP:WP5116 | 0.00115874451542 | 0.2 | TBK1 IKBKE | SARS CoV 2 B 1 1 7 variant antagonises innate immune activation |
| REAC:R-HSA-5218859 | 0.0012820759141 | 0.3 | BIRC2 BIRC3 TRAF2 | Regulated Necrosis |
| REAC:R-HSA-5357801 | 0.00143440477259 | 0.4 | BIRC2 TRAF2 BIRC3 DIABLO | Programmed Cell Death |
| GO:0140546 | 0.00193672398809 | 0.7 | TBK1 IKBKE TANK CXCL1 BIRC2 TRAF2 BIRC3 | defense response to symbiont |
| GO:0043123 | 0.00201553728028 | 0.5 | BIRC2 IKBKE BIRC3 TBK1 TRAF2 | positive regulation of canonical NF-kappaB signal transduction |
| GO:0098562 | 0.00263439368565 | 0.5 | TRAF1 BIRC2 TRAF2 HTRA2 DIABLO | cytoplasmic side of membrane |
| CORUM:6344 | 0.00278671748515 | 0.2 | BIRC3 TRAF2 | TNF-R1-associated signaling complex |
| GO:0098542 | 0.00327410463119 | 0.7 | TBK1 IKBKE TANK CXCL1 BIRC2 TRAF2 BIRC3 | defense response to other organism |
| KEGG:04936 | 0.00344875538076 | 0.3 | TBK1 CXCL1 IKBKE | Alcoholic liver disease |
| WP:WP5182 | 0.00375768007348 | 0.2 | BIRC3 TRAF2 | Pro survival signaling of neuroprotectin D1 |
| KEGG:05160 | 0.00406147233016 | 0.3 | TBK1 TRAF2 IKBKE | Hepatitis C |
| GO:1902531 | 0.00445655560981 | 0.8 | TBK1 TRAF1 IKBKE TANK HTRA2 BIRC3 BIRC2 TRAF2 | regulation of intracellular signal transduction |
| GO:0052547 | 0.0045538824629 | 0.5 | BIRC2 TANK BIRC3 DIABLO HTRA2 | regulation of peptidase activity |
| KEGG:04217 | 0.00464015230994 | 0.3 | BIRC2 BIRC3 TRAF2 | Necroptosis |
| REAC:R-HSA-5668541 | 0.00553477986945 | 0.3 | BIRC2 BIRC3 TRAF2 | TNFR2 non-canonical NF-kB pathway |
| GO:0033209 | 0.00555894987576 | 0.4 | TRAF1 BIRC2 BIRC3 TRAF2 | tumor necrosis factor-mediated signaling pathway |
| REAC:R-HSA-168256 | 0.00569735174379 | 0.7 | TBK1 IKBKE TANK CXCL1 BIRC2 TRAF2 BIRC3 | Immune System |
| KEGG:05022 | 0.00585983148306 | 0.4 | TBK1 TRAF2 HTRA2 TANK | Pathways of neurodegeneration - multiple diseases |
| WP:WP4961 | 0.00630863869434 | 0.2 | TBK1 IKBKE | STING pathway in Kawasaki like disease and COVID 19 |
| REAC:R-HSA-1280215 | 0.00631919703118 | 0.5 | BIRC2 TRAF2 CXCL1 TBK1 BIRC3 | Cytokine Signaling in Immune system |
| KEGG:05202 | 0.00669362487232 | 0.3 | BIRC2 BIRC3 TRAF1 | Transcriptional misregulation in cancer |
| WP:WP2507 | 0.00704825789595 | 0.2 | HTRA2 DIABLO | Nanomaterial induced apoptosis |
| GO:0042221 | 0.00710882710048 | 0.9 | TBK1 TRAF1 IKBKE TANK HTRA2 CXCL1 BIRC2 TRAF2 BIRC3 | response to chemical |
| KEGG:05200 | 0.00781674670163 | 0.4 | TRAF1 BIRC2 BIRC3 TRAF2 | Pathways in cancer |
| REAC:R-HSA-918233 | 0.00922174626729 | 0.2 | TBK1 IKBKE | TRAF3-dependent IRF activation pathway |
| WP:WP4868 | 0.0104129071256 | 0.2 | TBK1 IKBKE | Type I interferon induction and signaling during SARS CoV 2 infection |
| KEGG:05169 | 0.0104169791335 | 0.3 | TBK1 TRAF2 IKBKE | Epstein-Barr virus infection |
| GO:0043207 | 0.0106721287469 | 0.7 | TBK1 IKBKE TANK CXCL1 BIRC2 TRAF2 BIRC3 | response to external biotic stimulus |
| GO:0051707 | 0.0106721287469 | 0.7 | TBK1 IKBKE TANK CXCL1 BIRC2 TRAF2 BIRC3 | response to other organism |
| WP:WP3851 | 0.0123383084162 | 0.2 | TBK1 IKBKE | TLR4 signaling and tolerance |
| GO:0009607 | 0.0133547668429 | 0.7 | TBK1 IKBKE TANK CXCL1 BIRC2 TRAF2 BIRC3 | response to biotic stimulus |
| WP:WP4950 | 0.0133616217617 | 0.2 | TRAF1 TRAF2 | 16p11 2 distal deletion syndrome |
| WP:WP3858 | 0.0144252840529 | 0.2 | TBK1 IKBKE | Toll like receptor signaling related to MyD88 |
| GO:0065009 | 0.0144267386478 | 0.8 | TRAF1 DIABLO IKBKE TANK HTRA2 BIRC3 BIRC2 TRAF2 | regulation of molecular function |
| WP:WP5406 | 0.0155292506893 | 0.2 | TRAF1 TRAF2 | 13q12 12 copy number variation |
| WP:WP5038 | 0.0166734771023 | 0.2 | TBK1 IKBKE | Mitochondrial immune response to SARS CoV 2 |
| WP:WP4880 | 0.0166734771023 | 0.2 | TBK1 IKBKE | Host pathogen interaction of human coronaviruses interferon induction |
| REAC:R-HSA-168927 | 0.0172971739669 | 0.2 | BIRC2 BIRC3 | TICAM1, RIP1-mediated IKK complex recruitment |
| WP:WP5115 | 0.0174994953665 | 0.3 | TBK1 CXCL1 TRAF2 | Network map of SARS CoV 2 signaling pathway |
| WP:WP4912 | 0.0178579187559 | 0.2 | TBK1 IKBKE | SARS coronavirus and innate immunity |
| WP:WP3617 | 0.0178579187559 | 0.2 | BIRC2 BIRC3 | Photodynamic therapy induced NF kB survival signaling |
| GO:0051247 | 0.0184430953548 | 0.7 | TBK1 DIABLO TANK HTRA2 BIRC3 BIRC2 TRAF2 | positive regulation of protein metabolic process |
| REAC:R-HSA-162582 | 0.0190896791054 | 0.7 | TRAF1 TBK1 IKBKE CXCL1 BIRC2 TRAF2 BIRC3 | Signal Transduction |
| REAC:R-HSA-937041 | 0.0192120670931 | 0.2 | BIRC2 BIRC3 | IKK complex recruitment mediated by RIP1 |
| KEGG:05132 | 0.0198241007008 | 0.3 | BIRC2 BIRC3 TRAF2 | Salmonella infection |
| GO:0045087 | 0.025792148361 | 0.6 | IKBKE TBK1 TANK BIRC3 BIRC2 TRAF2 | innate immune response |
| WP:WP3941 | 0.025806598747 | 0.2 | TRAF1 TRAF2 | Oxidative damage response |
| GO:0044419 | 0.02619051563 | 0.7 | TBK1 IKBKE TANK CXCL1 BIRC2 TRAF2 BIRC3 | biological process involved in interspecies interaction between organisms |
| WP:000000 | 0.029871335992 | 1.0 | TBK1 DIABLO TRAF1 IKBKE TANK HTRA2 CXCL1 BIRC2 TRAF2 BIRC3 | WIKIPATHWAYS |
| GO:0006952 | 0.0383090432641 | 0.7 | TBK1 IKBKE TANK CXCL1 BIRC2 TRAF2 BIRC3 | defense response |
| REAC:R-HSA-109581 | 0.0393375504084 | 0.3 | BIRC2 DIABLO TRAF2 | Apoptosis |
| GO:0007165 | 0.0393905455079 | 1.0 | TBK1 DIABLO TRAF1 IKBKE TANK HTRA2 CXCL1 BIRC2 TRAF2 BIRC3 | signal transduction |
| WP:WP2018 | 0.0422420407673 | 0.2 | TRAF1 TRAF2 | RANKL RANK signaling pathway |
| GO:0006955 | 0.0423392654243 | 0.7 | TBK1 IKBKE TANK CXCL1 BIRC2 TRAF2 BIRC3 | immune response |
| REAC:R-HSA-5689880 | 0.0483498248961 | 0.3 | BIRC2 BIRC3 TRAF2 | Ub-specific processing proteases |
| REAC:R-HSA-168638 | 0.0499343626014 | 0.2 | BIRC2 BIRC3 | NOD1/2 Signaling Pathway |
| KEGG:01524 | 0.0499839039158 | 0.2 | BIRC2 BIRC3 | Platinum drug resistance |
| KEGG:04623 | 0.0499839039158 | 0.2 | TBK1 IKBKE | Cytosolic DNA-sensing pathway |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TRAF2 | TRAF1 | 1.0 | 0.088 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| BIRC2 | DIABLO | 1.0 | 0.128 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| BIRC2 | TRAF1 | 0.999 | 0.166 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| TANK | TRAF1 | 0.999 | 0.136 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TANK | TRAF2 | 0.999 | 0.148952380952 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| BIRC2 | TRAF2 | 0.999 | 0.2272 |
mutually_exclusive (Q13077)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| TRAF1 | TBK1 | 0.999 | 0.124 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TANK | TBK1 | 0.998 | 0.194 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| BIRC2 | HTRA2 | 0.998 | 0.124 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TRAF2 | TBK1 | 0.998 | 0.06 | youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| TRAF2 | DIABLO | 0.996 | 0.074 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| BIRC2 | CXCL1 | 0.995 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| HTRA2 | TRAF2 | 0.994 | 0.034 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| TANK | DIABLO | 0.993 | 0.128 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CXCL1 | TRAF2 | 0.987 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TRAF1 | DIABLO | 0.986 | 0.168 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| CXCL1 | TBK1 | 0.984 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TANK | IKBKE | 0.98 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| HTRA2 | TRAF1 | 0.98 | 0.092 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TRAF2 | IKBKE | 0.976 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| HTRA2 | DIABLO | 0.973 | 0.374 | bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| BIRC3 | TRAF2 | 0.969 |
mutually_exclusive (Q9NR28)
|
bioplex3_WMM bioplex3_HCT116 WMM_only | |
| BIRC3 | TRAF1 | 0.966 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| BIRC3 | DIABLO | 0.964 |
structurally_consistent (dimer)
|
bioplex3_WMM bioplex3_HCT116 WMM_only | |
| BIRC2 | TANK | 0.955 | 0.172 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| HTRA2 | TANK | 0.952 | 0.096 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| CXCL1 | DIABLO | 0.952 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| BIRC2 | TBK1 | 0.939 | 0.184 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| BIRC3 | IKBKE | 0.892 | bioplex3_WMM WMM_only | ||
| TBK1 | DIABLO | 0.858 | 0.052 | youn () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only | |
| TRAF1 | IKBKE | 0.796 | bioplex3_WMM WMM_only | ||
| BIRC2 | IKBKE | 0.492 | bioplex3_WMM WMM_only | ||
| IKBKE | TBK1 | 0.456 |
structurally_consistent (dimer)
|
bioplex3_WMM WMM_only | |
| HTRA2 | IKBKE | 0.451 | bioplex3_WMM WMM_only | ||
| BIRC2 | BIRC3 | 0.438 | bioplex3_WMM WMM_only | ||
| BIRC3 | TANK | 0.384 | bioplex3_WMM WMM_only | ||
| IKBKE | DIABLO | 0.374 | bioplex3_WMM WMM_only | ||
| BIRC3 | TBK1 | 0.373 | bioplex3_WMM WMM_only | ||
| BIRC3 | HTRA2 | 0.306 | bioplex3_WMM WMM_only | ||
| HTRA2 | TBK1 | 0.277 | 0.042 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| CXCL1 | TANK | 0.043 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes