hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_09542.1

Complex Portal: CPX-12142

Confidence: Moderate High

Genename	Protein Name	Uniprot Annotation Score	Links
CGN	Cingulin	5	UniProt NCBI
TMOD1	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod)	5	UniProt NCBI
SIPA1L3	Signal-induced proliferation-associated 1-like protein 3 (SIPA1-like protein 3) (SPA-1-like protein 3)	5	UniProt NCBI
SIPA1L1	Signal-induced proliferation-associated 1-like protein 1 (SIPA1-like protein 1) (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6-targeted protein 1)	5	UniProt NCBI
MYO1B	Unconventional myosin-Ib (MYH-1c) (Myosin I alpha) (MMI-alpha) (MMIa)	5	UniProt NCBI
MPRIP	Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)	5	UniProt NCBI
CDC42	Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)	5	UniProt NCBI
TPM4	Tropomyosin alpha-4 chain (TM30p1) (Tropomyosin-4)	5	UniProt NCBI
DOCK7	Dedicator of cytokinesis protein 7	5	UniProt NCBI
LMO7	LIM domain only protein 7 (LMO-7) (F-box only protein 20) (LOMP)	5	UniProt NCBI
PPP1R9A	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A)	5	UniProt NCBI
NCKIPSD	NCK-interacting protein with SH3 domain (54 kDa VacA-interacting protein) (54 kDa vimentin-interacting protein) (VIP54) (90 kDa SH3 protein interacting with Nck) (AF3p21) (Dia-interacting protein 1) (DIP-1) (Diaphanous protein-interacting protein) (SH3 adapter protein SPIN90) (WASP-interacting SH3-domain protein) (WISH) (Wiskott-Aldrich syndrome protein-interacting protein)	5	UniProt NCBI
COBL	Protein cordon-bleu	5	UniProt NCBI
ERC1	ELKS/Rab6-interacting/CAST family member 1 (ERC-1) (Rab6-interacting protein 2)	5	UniProt NCBI
TPM1	Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)	5	UniProt NCBI
ARHGAP21	Rho GTPase-activating protein 21 (Rho GTPase-activating protein 10) (Rho-type GTPase-activating protein 21)	5	UniProt NCBI
ITPRID2	Protein ITPRID2 (Cleavage signal-1 protein) (CS-1) (ITPR-interacting domain-containing protein 2) (Ki-ras-induced actin-interacting protein) (Sperm-specific antigen 2)	5	UniProt NCBI
RAI14	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Novel retinal pigment epithelial cell protein) (Retinoic acid-induced protein 14)	5	UniProt NCBI
LRRFIP2	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII-interacting protein 2)	5	UniProt NCBI
ARHGAP11A	Rho GTPase-activating protein 11A (Rho-type GTPase-activating protein 11A)	4	UniProt NCBI
SPECC1L	Cytospin-A (Renal carcinoma antigen NY-REN-22) (Sperm antigen with calponin homology and coiled-coil domains 1-like) (SPECC1-like protein)	5	UniProt NCBI
PLEKHG3	Pleckstrin homology domain-containing family G member 3 (PH domain-containing family G member 3)	5	UniProt NCBI
DENND2B	DENN domain-containing protein 2B (HeLa tumor suppression 1) (Suppression of tumorigenicity 5 protein)	5	UniProt NCBI
ABLIM1	Actin-binding LIM protein 1 (abLIM-1) (Actin-binding LIM protein family member 1) (Actin-binding double zinc finger protein) (LIMAB1) (Limatin)	5	UniProt NCBI
MYL12B	Myosin regulatory light chain 12B (MLC-2A) (MLC-2) (Myosin regulatory light chain 2-B, smooth muscle isoform) (Myosin regulatory light chain 20 kDa) (MLC20) (Myosin regulatory light chain MRLC2) (SHUJUN-1)	5	UniProt NCBI
LIMA1	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm)	5	UniProt NCBI
PPP1R9B	Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)	5	UniProt NCBI
SSH1	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 1) (SSH-1L) (hSSH-1L)	5	UniProt NCBI
PPP1R12A	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit)	5	UniProt NCBI
TPM3	Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)	5	UniProt NCBI
RACGAP1	Rac GTPase-activating protein 1 (Male germ cell RacGap) (MgcRacGAP) (Protein CYK4 homolog) (CYK4) (HsCYK-4)	5	UniProt NCBI
ARHGEF17	Rho guanine nucleotide exchange factor 17 (164 kDa Rho-specific guanine-nucleotide exchange factor) (p164-RhoGEF) (p164RhoGEF) (Tumor endothelial marker 4)	4	UniProt NCBI
LRCH3	DISP complex protein LRCH3 (Leucine-rich repeat and calponin homology domain-containing protein 3)	5	UniProt NCBI
LIMCH1	LIM and calponin homology domains-containing protein 1	5	UniProt NCBI
SIPA1	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase-activating protein Spa-1) (p130 SPA-1)	5	UniProt NCBI
PHLDB2	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta)	5	UniProt NCBI
NEXN	Nexilin (F-actin-binding protein) (Nelin)	5	UniProt NCBI
SRGAP2	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2) (Rho GTPase-activating protein 34)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0007010	2.55573391995e-15	0.675675675676	COBL TPM3 RACGAP1 ARHGEF17 PPP1R12A CGN LRCH3 LIMCH1 SIPA1L3 SIPA1 SIPA1L1 NEXN PHLDB2 MYO1B SPECC1L SRGAP2 CDC42 TPM4 DOCK7 LIMA1 PPP1R9A PPP1R9B NCKIPSD SSH1 TPM1	cytoskeleton organization
GO:0015629	9.21108964433e-15	0.486486486486	MYL12B MYO1B COBL PPP1R9A PPP1R9B MPRIP LIMA1 ABLIM1 SIPA1L3 NEXN TPM1 TPM3 SIPA1L1 PPP1R12A TPM4 LIMCH1 ARHGAP21 SPECC1L	actin cytoskeleton
GO:0003779	3.05875398198e-12	0.405405405405	CGN COBL MYO1B TPM3 MPRIP PLEKHG3 LIMA1 SSH1 PPP1R9A TPM1 PPP1R9B TPM4 NEXN ABLIM1 ITPRID2	actin binding
GO:0030029	6.347970447e-10	0.459459459459	PPP1R9B MYO1B COBL PPP1R9A ARHGEF17 LIMCH1 SRGAP2 LIMA1 TPM3 CDC42 TPM1 TPM4 RACGAP1 SIPA1L1 PHLDB2 SSH1 SPECC1L	actin filament-based process
GO:0008092	6.82011798013e-10	0.486486486486	PPP1R9B CGN COBL MYO1B TPM3 MPRIP PLEKHG3 LIMA1 SSH1 PPP1R9A NEXN TPM1 NCKIPSD RACGAP1 TPM4 LIMCH1 ABLIM1 ITPRID2	cytoskeletal protein binding
GO:0005856	1.63631984963e-09	0.621621621622	COBL ERC1 RACGAP1 ARHGAP21 PPP1R12A LIMCH1 SIPA1L3 SIPA1L1 NEXN PHLDB2 MYO1B SPECC1L MPRIP TPM3 CDC42 TPM4 ABLIM1 MYL12B LIMA1 PPP1R9A PPP1R9B NCKIPSD TPM1	cytoskeleton
GO:0030036	2.34511571404e-09	0.432432432432	PPP1R9B MYO1B COBL PPP1R9A ARHGEF17 LIMCH1 LIMA1 TPM3 CDC42 TPM1 TPM4 RACGAP1 SIPA1L1 PHLDB2 SSH1 SPECC1L	actin cytoskeleton organization
GO:0051015	1.17393003492e-08	0.297297297297	MYO1B ITPRID2 MPRIP LIMA1 TPM3 PPP1R9A TPM1 TPM4 NEXN ABLIM1 PPP1R9B	actin filament binding
GO:0097517	3.59351565457e-08	0.216216216216	MYL12B LIMCH1 LIMA1 TPM3 SIPA1L3 TPM1 TPM4 ABLIM1	contractile actin filament bundle
GO:0001725	3.59351565457e-08	0.216216216216	MYL12B LIMCH1 LIMA1 TPM3 SIPA1L3 TPM1 TPM4 ABLIM1	stress fiber
GO:0006996	5.63995448102e-08	0.72972972973	COBL TPM3 TPM1 ARHGEF17 PPP1R12A CGN LRCH3 LIMCH1 ARHGAP21 SIPA1L3 SIPA1 SIPA1L1 NEXN PHLDB2 MYO1B SPECC1L SRGAP2 CDC42 TPM4 ABLIM1 DOCK7 LIMA1 PPP1R9A PPP1R9B NCKIPSD SSH1 RACGAP1	organelle organization
GO:0032432	7.59114010513e-08	0.216216216216	MYL12B LIMCH1 LIMA1 TPM3 SIPA1L3 TPM1 TPM4 ABLIM1	actin filament bundle
GO:0042641	8.74351928579e-08	0.216216216216	MYL12B LIMCH1 LIMA1 TPM3 SIPA1L3 TPM1 TPM4 ABLIM1	actomyosin
REAC:R-HSA-194315	7.16822895484e-07	0.351351351351	DOCK7 MYL12B TPM3 SRGAP2 PLEKHG3 ARHGAP11A CDC42 RACGAP1 ARHGEF17 TPM4 NCKIPSD ARHGAP21 PPP1R12A	Signaling by Rho GTPases
REAC:R-HSA-9716542	9.35549870345e-07	0.351351351351	DOCK7 MYL12B TPM3 SRGAP2 PLEKHG3 ARHGAP11A CDC42 RACGAP1 ARHGEF17 TPM4 NCKIPSD ARHGAP21 PPP1R12A	Signaling by Rho GTPases, Miro GTPases and RHOBTB3
GO:0007015	1.02664806839e-06	0.324324324324	MYO1B COBL CDC42 LIMCH1 LIMA1 TPM3 PPP1R9A TPM1 TPM4 PHLDB2 SSH1 PPP1R9B	actin filament organization
REAC:R-HSA-9012999	1.09660011452e-05	0.27027027027	DOCK7 TPM3 SRGAP2 PLEKHG3 ARHGAP11A CDC42 RACGAP1 ARHGEF17 TPM4 ARHGAP21	RHO GTPase cycle
GO:0030054	2.87291665856e-05	0.459459459459	CGN PPP1R12A SIPA1L3 MPRIP SRGAP2 DOCK7 PPP1R9A ERC1 LIMA1 CDC42 PPP1R9B TPM4 SIPA1L1 PHLDB2 LMO7 ARHGAP21 NEXN	cell junction
GO:0060589	3.40574245378e-05	0.297297297297	DOCK7 SRGAP2 ARHGEF17 SIPA1 PLEKHG3 ARHGAP11A SIPA1L3 DENND2B SIPA1L1 ARHGAP21 RACGAP1	nucleoside-triphosphatase regulator activity
GO:0030695	3.40574245378e-05	0.297297297297	DOCK7 SRGAP2 ARHGEF17 SIPA1 PLEKHG3 ARHGAP11A SIPA1L3 DENND2B SIPA1L1 ARHGAP21 RACGAP1	GTPase regulator activity
HPA:0031323	0.000158877484189	0.135135135135	LIMA1 CGN COBL TPM3 TPM1	appendix; enterocytes - Microvilli[High]
HPA:0131323	0.000210794025654	0.135135135135	LIMA1 CGN COBL TPM3 TPM1	colon; enterocytes - Microvilli[High]
REAC:R-HSA-9013148	0.000226814701254	0.162162162162	DOCK7 SRGAP2 PLEKHG3 CDC42 RACGAP1 ARHGAP21	CDC42 GTPase cycle
HPA:0401322	0.000277894069649	0.162162162162	CGN MYL12B LIMA1 TPM3 TPM1 COBL	rectum; enterocytes - Microvilli[>=Medium]
HPA:0401323	0.000400086846473	0.135135135135	LIMA1 CGN COBL TPM3 TPM1	rectum; enterocytes - Microvilli[High]
HPA:0401321	0.000537130190417	0.162162162162	CGN MYL12B LIMA1 TPM3 TPM1 COBL	rectum; enterocytes - Microvilli[>=Low]
HPA:0481323	0.000565727175233	0.135135135135	LIMA1 CGN COBL TPM3 TPM1	small intestine; enterocytes - Microvilli[High]
REAC:R-HSA-445355	0.000720845081496	0.108108108108	TPM3 TPM4 TPM1 MYL12B	Smooth Muscle Contraction
GO:0097435	0.000813917434674	0.324324324324	MYO1B COBL CDC42 LIMCH1 LIMA1 TPM3 PPP1R9A TPM1 TPM4 PHLDB2 SSH1 PPP1R9B	supramolecular fiber organization
REAC:R-HSA-9013149	0.000852653668617	0.162162162162	DOCK7 SRGAP2 PLEKHG3 CDC42 RACGAP1 ARHGAP21	RAC1 GTPase cycle
CORUM:817	0.0011216607179	0.0540540540541	MPRIP PPP1R12A	MRIP-MBS complex
HPA:0481321	0.00145650662978	0.162162162162	CGN MYL12B LIMA1 TPM3 TPM1 COBL	small intestine; enterocytes - Microvilli[>=Low]
GO:0016043	0.00153856306756	0.756756756757	COBL TPM3 RACGAP1 ARHGEF17 PPP1R12A CGN LRCH3 LIMCH1 ARHGAP21 SIPA1L3 SIPA1 SIPA1L1 NEXN PHLDB2 MYO1B SPECC1L SRGAP2 ERC1 CDC42 TPM4 ABLIM1 DOCK7 LIMA1 PPP1R9A PPP1R9B NCKIPSD SSH1 TPM1	cellular component organization
KEGG:04360	0.00266945605623	0.135135135135	SSH1 CDC42 SRGAP2 ABLIM1 MYL12B	Axon guidance
GO:0005862	0.00298219742351	0.0810810810811	TPM4 TPM1 TPM3	muscle thin filament tropomyosin
REAC:R-HSA-9013406	0.0031049405793	0.108108108108	CDC42 SRGAP2 ARHGAP21 PLEKHG3	RHOQ GTPase cycle
CORUM:815	0.00335960911255	0.0540540540541	MPRIP PPP1R12A	MRIP-MBS-RHOA complex
KEGG:04814	0.0033998718323	0.135135135135	MYL12B MYO1B TPM1 TPM3 TPM4	Motor proteins
GO:0071840	0.00382694428011	0.756756756757	COBL TPM3 RACGAP1 ARHGEF17 PPP1R12A CGN LRCH3 LIMCH1 ARHGAP21 SIPA1L3 SIPA1 SIPA1L1 NEXN PHLDB2 MYO1B SPECC1L SRGAP2 ERC1 CDC42 TPM4 ABLIM1 DOCK7 LIMA1 PPP1R9A PPP1R9B NCKIPSD SSH1 TPM1	cellular component organization or biogenesis
HPA:0031322	0.00404202980367	0.135135135135	LIMA1 CGN COBL TPM3 TPM1	appendix; enterocytes - Microvilli[>=Medium]
REAC:R-HSA-8980692	0.00512270726939	0.135135135135	RACGAP1 ARHGEF17 ARHGAP21 PLEKHG3 ARHGAP11A	RHOA GTPase cycle
HPA:0151322	0.00517718633766	0.135135135135	LIMA1 CGN COBL TPM3 TPM1	duodenum; enterocytes - Microvilli[>=Medium]
GO:0005884	0.00524098495661	0.162162162162	MYO1B COBL TPM3 TPM1 TPM4 SPECC1L	actin filament
REAC:R-HSA-5627123	0.00551009817555	0.0810810810811	CDC42 MYL12B PPP1R12A	RHO GTPases activate PAKs
HPA:0031321	0.00793014565265	0.135135135135	LIMA1 CGN COBL TPM3 TPM1	appendix; enterocytes - Microvilli[>=Low]
HPA:0131322	0.00843855772478	0.135135135135	LIMA1 CGN COBL TPM3 TPM1	colon; enterocytes - Microvilli[>=Medium]
GO:0030234	0.00863117002653	0.351351351351	DOCK7 SRGAP2 PPP1R12A ARHGEF17 SIPA1 PLEKHG3 ARHGAP11A SIPA1L3 DENND2B RACGAP1 SIPA1L1 ARHGAP21 PPP1R9B	enzyme regulator activity
GO:0005925	0.00886095403197	0.243243243243	DOCK7 PPP1R12A MPRIP LIMA1 CDC42 LMO7 TPM4 PHLDB2 NEXN	focal adhesion
GO:0070161	0.0103770427489	0.297297297297	CGN PPP1R12A DOCK7 MPRIP LIMA1 CDC42 SIPA1L3 TPM4 LMO7 PHLDB2 NEXN	anchoring junction
GO:0030055	0.0104605786342	0.243243243243	DOCK7 PPP1R12A MPRIP LIMA1 CDC42 LMO7 TPM4 PHLDB2 NEXN	cell-substrate junction
HPA:0481322	0.0107299589725	0.135135135135	LIMA1 CGN COBL TPM3 TPM1	small intestine; enterocytes - Microvilli[>=Medium]
HPA:0151321	0.0113715819938	0.135135135135	LIMA1 CGN COBL TPM3 TPM1	duodenum; enterocytes - Microvilli[>=Low]
WP:WP383	0.0113859162068	0.0810810810811	TPM4 TPM1 TPM3	Striated muscle contraction pathway
HPA:0131321	0.0117033223561	0.135135135135	LIMA1 CGN COBL TPM3 TPM1	colon; enterocytes - Microvilli[>=Low]
GO:0005096	0.0119005851799	0.189189189189	SRGAP2 ARHGAP11A SIPA1L3 RACGAP1 SIPA1L1 ARHGAP21 SIPA1	GTPase activator activity
REAC:R-HSA-9013423	0.0212140405507	0.108108108108	CDC42 SRGAP2 ARHGAP21 RACGAP1	RAC3 GTPase cycle
GO:0043232	0.02427797255	0.648648648649	COBL ERC1 RAI14 TPM1 ARHGAP21 PPP1R12A LIMCH1 SIPA1L3 SIPA1L1 NEXN PHLDB2 MYO1B SPECC1L MPRIP TPM3 CDC42 TPM4 ABLIM1 MYL12B LIMA1 PPP1R9A PPP1R9B NCKIPSD RACGAP1	intracellular non-membrane-bounded organelle
GO:0043228	0.02427797255	0.648648648649	COBL ERC1 RAI14 TPM1 ARHGAP21 PPP1R12A LIMCH1 SIPA1L3 SIPA1L1 NEXN PHLDB2 MYO1B SPECC1L MPRIP TPM3 CDC42 TPM4 ABLIM1 MYL12B LIMA1 PPP1R9A PPP1R9B NCKIPSD RACGAP1	non-membrane-bounded organelle
GO:0051017	0.0242791370034	0.162162162162	MYO1B LIMA1 LIMCH1 CDC42 TPM1 PHLDB2	actin filament bundle assembly
GO:0000902	0.0255737297943	0.27027027027	DOCK7 COBL CDC42 SRGAP2 SIPA1L3 TPM1 SIPA1L1 NEXN SSH1 SIPA1	cell morphogenesis
REAC:R-HSA-390522	0.0257799274652	0.0810810810811	TPM4 TPM1 TPM3	Striated Muscle Contraction
GO:0061572	0.0267924330589	0.162162162162	MYO1B LIMA1 LIMCH1 CDC42 TPM1 PHLDB2	actin filament bundle organization
REAC:R-HSA-9013424	0.0308178798665	0.0810810810811	CDC42 TPM3 TPM4	RHOV GTPase cycle
HPA:0131302	0.0335507046727	0.162162162162	CGN COBL LIMA1 TPM3 RACGAP1 TPM1	colon; enterocytes[>=Medium]
GO:0030016	0.0390784807994	0.162162162162	PPP1R12A TPM3 TPM1 MYL12B TPM4 NEXN	myofibril
GO:0099512	0.0409907376776	0.27027027027	MYL12B MYO1B COBL TPM3 TPM1 TPM4 PPP1R12A NCKIPSD NEXN SPECC1L	supramolecular fiber
GO:0099081	0.0459319946433	0.27027027027	MYL12B MYO1B COBL TPM3 TPM1 TPM4 PPP1R12A NCKIPSD NEXN SPECC1L	supramolecular polymer

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
DOCK7	LRCH3	1.0
TPM1	TPM4	1.0
TMOD1	LRRFIP2	0.999	0.042
SIPA1L1	SIPA1L3	0.999	0.112
TPM3	TPM4	0.999	0.158
LIMCH1	SSH1	0.998	0.104
NEXN	LIMA1	0.998
TPM1	TPM3	0.997
SSH1	TMOD1	0.997	0.112
RACGAP1	PHLDB2	0.997	0.082
PPP1R9B	LRRFIP2	0.997	0.09
PPP1R9A	PPP1R9B	0.997	0.448
LMO7	PPP1R9B	0.996	0.056
LMO7	TMOD1	0.996	0.088
PPP1R9B	LIMA1	0.996	0.044
NEXN	MYO1B	0.996
LIMCH1	TMOD1	0.996	0.052
SIPA1	SIPA1L1	0.996	0.046
SPECC1L	RAI14	0.995	0.18
PPP1R9A	RAI14	0.995	0.09
CGN	LMO7	0.995	0.142
NCKIPSD	CGN	0.995	0.048
MPRIP	RAI14	0.995
ITPRID2	CGN	0.995	0.056
PPP1R9A	NEXN	0.995
NCKIPSD	SIPA1L3	0.995	0.076
CGN	PHLDB2	0.995	0.076
ITPRID2	PHLDB2	0.995	0.098
MYO1B	LIMA1	0.995	0.112
SIPA1	ITPRID2	0.995	0.02
LIMCH1	LIMA1	0.995	0.054
SIPA1	SIPA1L3	0.994	0.032
NCKIPSD	SPECC1L	0.994	0.074
TPM1	RAI14	0.994
DENND2B	ARHGAP21	0.994	0.128
ARHGEF17	PHLDB2	0.994	0.08
NCKIPSD	SSH1	0.994	0.1
NEXN	LMO7	0.994
PPP1R9A	LIMA1	0.994	0.084
MPRIP	SPECC1L	0.994
ITPRID2	ARHGAP21	0.994	0.096
MPRIP	LRRFIP2	0.993
SIPA1L1	PHLDB2	0.993	0.108
TMOD1	LIMA1	0.993	0.038
SIPA1L3	PHLDB2	0.993	0.054
PLEKHG3	TMOD1	0.993	0.09
PLEKHG3	PPP1R9B	0.993	0.102
ARHGEF17	SIPA1	0.993	0.084
ARHGEF17	ITPRID2	0.993	0.08
CGN	PPP1R9B	0.993	0.072
MYL12B	MYO1B	0.993	0.076
MYO1B	LRRFIP2	0.993	0.042
LRRFIP2	LIMA1	0.993	0.07
TPM1	LIMA1	0.993
SPECC1L	PPP1R9B	0.992	0.042
ITPRID2	SIPA1L3	0.992	0.138
NEXN	LRRFIP2	0.992
CGN	SIPA1L3	0.992	0.172
PPP1R9A	LRRFIP2	0.992	0.05
MYL12B	LIMA1	0.992	0.238
PPP1R9A	PLEKHG3	0.992	0.134
ITPRID2	SIPA1L1	0.992	0.096
ARHGEF17	SIPA1L3	0.992	0.266
SPECC1L	LIMA1	0.992	0.028
CGN	ARHGAP21	0.992	0.132
PPP1R12A	LRCH3	0.992	0.07
LMO7	LIMA1	0.992	0.182
TPM1	NEXN	0.992
PLEKHG3	DOCK7	0.992
MPRIP	NEXN	0.991
MPRIP	PPP1R9A	0.991
SIPA1	CGN	0.991	0.13
SPECC1L	NEXN	0.991
MPRIP	TPM1	0.991
ARHGEF17	CGN	0.991	0.116
NEXN	TPM4	0.991
MPRIP	ARHGAP21	0.991
SIPA1	ARHGAP21	0.991	0.078
SIPA1	ABLIM1	0.991
SPECC1L	LMO7	0.99	0.106
LIMCH1	NEXN	0.99
SPECC1L	TMOD1	0.99	0.062
TPM4	TMOD1	0.99	0.112
SIPA1	PHLDB2	0.99	0.026
CGN	SIPA1L1	0.99	0.066
SIPA1L1	ARHGAP21	0.99	0.122
SIPA1	RAI14	0.99	0.0789
ARHGAP21	SIPA1L3	0.99	0.189058823529
SIPA1L1	ABLIM1	0.99
TPM3	LIMA1	0.99	0.128
RAI14	LRCH3	0.99	0.054
PLEKHG3	ARHGAP21	0.989	0.252
DENND2B	PHLDB2	0.989	0.11
NEXN	RAI14	0.989
RAI14	LRRFIP2	0.989	0.094
DENND2B	SIPA1L3	0.989	0.132
NCKIPSD	LMO7	0.989	0.024
MYO1B	TMOD1	0.989	0.062
PPP1R9A	TMOD1	0.989	0.07
NEXN	PPP1R9B	0.989
DOCK7	COBL	0.988
LIMCH1	NCKIPSD	0.988	0.036
ABLIM1	SIPA1L3	0.988
NEXN	TMOD1	0.988
SPECC1L	CGN	0.988	0.042
CGN	ABLIM1	0.988
SPECC1L	LRRFIP2	0.988	0.08
RAI14	PPP1R9B	0.988	0.04
ARHGEF17	MPRIP	0.988
DENND2B	CGN	0.987	0.08
TPM3	TMOD1	0.987	0.074
PLEKHG3	RAI14	0.987	0.194
PLEKHG3	SIPA1L3	0.987	0.188
NEXN	PLEKHG3	0.987
RAI14	CGN	0.987	0.1
DENND2B	ABLIM1	0.986
DENND2B	SIPA1L1	0.986	0.096
LIMCH1	TPM4	0.986	0.05
LIMCH1	LMO7	0.985	0.196
PLEKHG3	LRRFIP2	0.985	0.064
SIPA1	DOCK7	0.985
RACGAP1	ITPRID2	0.985	0.132
SIPA1	PLEKHG3	0.985	0.078
ARHGAP21	ARHGAP11A	0.985	0.14
SPECC1L	TPM4	0.985	0.056
TPM1	SPECC1L	0.985
TPM1	TMOD1	0.985
TPM4	LIMA1	0.985	0.196
RACGAP1	DENND2B	0.985	0.150222222222
SPECC1L	PLEKHG3	0.984	0.104
NCKIPSD	SIPA1L1	0.984	0.052
RACGAP1	PLEKHG3	0.984	0.166
PPP1R9B	TMOD1	0.984	0.032
LIMCH1	TPM1	0.984
DENND2B	ARHGAP11A	0.983	0.138
LMO7	LRRFIP2	0.983	0.05
RACGAP1	SIPA1	0.983	0.042
LIMCH1	SPECC1L	0.983	0.142
NEXN	ARHGAP11A	0.983
NCKIPSD	ARHGAP21	0.982	0.084
LMO7	SIPA1L3	0.982	0.124
PLEKHG3	CGN	0.982	0.116
SPECC1L	PPP1R12A	0.982	0.182
CGN	TMOD1	0.982	0.066
RAI14	ARHGAP11A	0.982	0.166
MPRIP	ARHGAP11A	0.981
SPECC1L	SIPA1L3	0.981	0.05
ABLIM1	PHLDB2	0.981
MPRIP	ABLIM1	0.981
PLEKHG3	ARHGAP11A	0.981	0.192
NCKIPSD	CDC42	0.981	0.218
PPP1R9B	MYO1B	0.981	0.02
NCKIPSD	TMOD1	0.981	0.044
RAI14	SIPA1L1	0.981	0.076
MYL12B	SPECC1L	0.98	0.104
LIMCH1	PLEKHG3	0.98	0.256
TPM1	PPP1R9B	0.98
SPECC1L	TPM3	0.98	0.018
ABLIM1	LMO7	0.98
PLEKHG3	ABLIM1	0.98
SIPA1	LMO7	0.979	0.028
MPRIP	MYO1B	0.979
RAI14	TMOD1	0.979	0.112
DENND2B	SIPA1	0.978	0.044
TPM1	LMO7	0.978
ARHGEF17	DENND2B	0.978	0.174
PLEKHG3	LIMA1	0.978	0.098
MPRIP	PPP1R12A	0.978
MPRIP	PLEKHG3	0.977
SIPA1L1	DOCK7	0.977
ITPRID2	LMO7	0.977	0.076
PLEKHG3	PHLDB2	0.977	0.14
TMOD1	CDC42	0.977	0.384
MPRIP	DENND2B	0.976
ERC1	SIPA1L1	0.976	0.054
PLEKHG3	CDC42	0.976	0.42
LIMCH1	ARHGAP11A	0.975	0.14
NCKIPSD	ABLIM1	0.975
LIMCH1	PPP1R9B	0.975	0.044
PLEKHG3	SIPA1L1	0.975	0.11
DENND2B	DOCK7	0.975
COBL	LIMA1	0.975	0.076
ARHGAP11A	LIMA1	0.975	0.11
ARHGAP11A	PPP1R9B	0.974	0.11
SPECC1L	PPP1R9A	0.974	0.064
PLEKHG3	MYO1B	0.974	0.088
SPECC1L	MYO1B	0.974	0.062
SRGAP2	SIPA1	0.974	0.028
ARHGEF17	SPECC1L	0.973	0.102
LMO7	ARHGAP11A	0.973	0.154
SIPA1	NCKIPSD	0.973	0.042
TPM1	MYO1B	0.973
ARHGEF17	PLEKHG3	0.972	0.17
DENND2B	RAI14	0.972	0.208518518519
SPECC1L	SIPA1L1	0.972	0.028
SPECC1L	PHLDB2	0.972	0.062
TPM4	PPP1R9B	0.972	0.07
TPM1	LRRFIP2	0.972
ITPRID2	CDC42	0.971	0.261552182163
TPM1	PPP1R9A	0.971
ARHGAP21	PHLDB2	0.97	0.202
SIPA1	SPECC1L	0.97	0.03
LRCH3	LRRFIP2	0.97	0.022
SPECC1L	ITPRID2	0.969	0.056
SRGAP2	CGN	0.969	0.082
ITPRID2	ABLIM1	0.969
TPM4	ARHGAP11A	0.969	0.12
TPM4	LRRFIP2	0.969	0.06
SPECC1L	LRCH3	0.968	0.04
LMO7	ARHGAP21	0.968	0.144
MYL12B	PPP1R9B	0.967	0.062
DENND2B	ITPRID2	0.967	0.054
RAI14	PHLDB2	0.967	0.1
TPM1	PLEKHG3	0.967
SIPA1	PPP1R12A	0.967	0.148
TPM1	ABLIM1	0.967
DENND2B	SPECC1L	0.966	0.126
ARHGEF17	SIPA1L1	0.966	0.092
ARHGAP11A	LRRFIP2	0.966	0.056
SRGAP2	ERC1	0.965	0.12
PLEKHG3	PPP1R12A	0.965	0.176
PPP1R9A	PPP1R12A	0.965	0.088
DOCK7	LIMA1	0.965
MPRIP	ITPRID2	0.964
ERC1	SIPA1	0.964	0.042
SRGAP2	DENND2B	0.963	0.092
TPM1	COBL	0.962
DENND2B	PLEKHG3	0.962	0.204
ARHGEF17	RAI14	0.962	0.168
ARHGEF17	ARHGAP21	0.962	0.25	mutually_exclusive (P60953)
LIMCH1	LRRFIP2	0.962	0.034
COBL	LRRFIP2	0.962	0.06
NEXN	LRCH3	0.961
RACGAP1	ARHGAP21	0.961	0.236
PLEKHG3	LMO7	0.96	0.14
DENND2B	PPP1R12A	0.96	0.078
SIPA1L1	PPP1R12A	0.96	0.112
MYL12B	TMOD1	0.96	0.098
ITPRID2	DOCK7	0.96
RAI14	TPM4	0.959	0.056
ARHGEF17	LMO7	0.958	0.138
TPM3	ARHGAP21	0.958	0.118
NCKIPSD	LRRFIP2	0.957	0.034
MPRIP	TMOD1	0.957
ARHGAP11A	CDC42	0.957	0.236
DOCK7	SIPA1L3	0.957
SPECC1L	ABLIM1	0.957
TPM1	ARHGAP11A	0.956
PLEKHG3	TPM4	0.956	0.1
NCKIPSD	LIMA1	0.956	0.038
ITPRID2	RAI14	0.955	0.072
ERC1	SIPA1L3	0.955	0.08
SRGAP2	SIPA1L1	0.955	0.044
SPECC1L	CDC42	0.955	0.349222222222
SPECC1L	DOCK7	0.954
SPECC1L	ARHGAP21	0.954	0.15
SIPA1L1	LMO7	0.953	0.108
LMO7	TPM3	0.953	0.142
MYL12B	TPM4	0.953	0.362
ERC1	PHLDB2	0.953	0.022
MPRIP	TPM4	0.953
TPM3	PPP1R9B	0.952	0.0586666666667
LRCH3	LIMA1	0.952	0.03
NEXN	TPM3	0.952
ERC1	ABLIM1	0.952
CGN	DOCK7	0.95
ITPRID2	PPP1R12A	0.949	0.042
PPP1R12A	LIMA1	0.948	0.172
PPP1R12A	TMOD1	0.947	0.064
RAI14	TPM3	0.946	0.064
PPP1R9B	CDC42	0.945	0.200475836431
CGN	PPP1R12A	0.945	0.102
SPECC1L	ARHGAP11A	0.944	0.082
MYL12B	NCKIPSD	0.944	0.006
RAI14	LIMA1	0.943	0.066
LIMCH1	CGN	0.943	0.126
COBL	MYO1B	0.943	0.052
ARHGEF17	PPP1R12A	0.941	0.17
LIMCH1	CDC42	0.941	0.308
LRCH3	PPP1R9B	0.941	0.02
PLEKHG3	TPM3	0.941	0.0456
LIMCH1	ITPRID2	0.937	0.058
MPRIP	LIMA1	0.936
ARHGEF17	ABLIM1	0.936
RAI14	PPP1R12A	0.935	0.192
PPP1R12A	SIPA1L3	0.933	0.074
PLEKHG3	ITPRID2	0.933	0.256
RAI14	COBL	0.932	0.158
LIMCH1	SIPA1L1	0.932	0.13
NEXN	SSH1	0.93
ARHGAP21	LRCH3	0.928	0.088
LIMCH1	TPM3	0.928	0.062
LIMCH1	MYO1B	0.928	0.056
RACGAP1	SPECC1L	0.927	0.09
TPM1	PPP1R12A	0.926
ARHGAP11A	MYO1B	0.921	0.148
DOCK7	PHLDB2	0.92
MPRIP	COBL	0.918
ITPRID2	PPP1R9B	0.916	0.026
RAI14	ARHGAP21	0.916	0.16
CGN	LRRFIP2	0.913	0.05
ERC1	CGN	0.91	0.068
LIMCH1	PHLDB2	0.909	0.07
ITPRID2	LRRFIP2	0.909	0.024
ARHGAP21	COBL	0.909	0.272
ABLIM1	COBL	0.908
LIMCH1	COBL	0.908	0.19
COBL	SIPA1L3	0.908	0.102
ABLIM1	ARHGAP21	0.907
LRCH3	TMOD1	0.907	0.058
LMO7	TPM4	0.905	0.188
SRGAP2	SIPA1L3	0.903	0.10696
MYL12B	LRCH3	0.903	0.008
NCKIPSD	TPM4	0.903	0.078
PPP1R12A	PHLDB2	0.902	0.054
CGN	TPM4	0.9	0.054
NCKIPSD	ITPRID2	0.9	0.024
ABLIM1	LIMA1	0.899
TPM3	LRRFIP2	0.898	0.076
ITPRID2	MYO1B	0.895	0.058
NCKIPSD	PHLDB2	0.891	0.034
ARHGAP21	CDC42	0.891	0.358	structurally_consistent (dimer)
RAI14	DOCK7	0.891
COBL	LRCH3	0.89	0.052
RACGAP1	SIPA1L3	0.888	0.25077037037
DOCK7	LRRFIP2	0.888
DENND2B	NCKIPSD	0.887	0.092
DENND2B	LIMA1	0.886	0.046
DOCK7	TMOD1	0.886
ARHGEF17	TPM1	0.885
SSH1	PPP1R9B	0.885	0.138
NEXN	CGN	0.884
ARHGAP21	LIMA1	0.884	0.082
LIMCH1	MYL12B	0.883	0.056
DENND2B	CDC42	0.881	0.336
MYL12B	LRRFIP2	0.881	0.14
SIPA1L1	TPM3	0.878	0.092
NCKIPSD	PPP1R9B	0.876	0.05
MYL12B	ABLIM1	0.874
LMO7	SSH1	0.873	0.11
NCKIPSD	NEXN	0.864
RACGAP1	LMO7	0.863	0.0997142857143
MYL12B	RAI14	0.862	0.156
ERC1	DENND2B	0.862	0.068
SRGAP2	NCKIPSD	0.859	0.06
TPM1	MYL12B	0.857
MYL12B	TPM3	0.856	0.056
SSH1	LIMA1	0.856	0.078
PPP1R12A	LRRFIP2	0.855	0.168
ARHGEF17	DOCK7	0.853
PPP1R12A	COBL	0.851	0.072
RAI14	MYO1B	0.849	0.104
ARHGAP21	LRRFIP2	0.848	0.06
MYL12B	CGN	0.847	0.118
RAI14	LMO7	0.845	0.108
NEXN	DOCK7	0.843
PPP1R9A	ARHGAP11A	0.841	0.096
SIPA1L3	LIMA1	0.839	0.074
CGN	LIMA1	0.837	0.188
ARHGEF17	TMOD1	0.835	0.124
DOCK7	PPP1R9B	0.832
RAI14	ABLIM1	0.831
RACGAP1	PPP1R12A	0.83	0.146
MYL12B	NEXN	0.829
LIMCH1	ARHGAP21	0.829	0.202
TPM1	CDC42	0.828
TPM4	SSH1	0.827	0.112
RAI14	SIPA1L3	0.822	0.09
TMOD1	SIPA1L3	0.82	0.112
ABLIM1	LRRFIP2	0.819
TPM1	ITPRID2	0.817
ABLIM1	TPM3	0.815
PLEKHG3	LRCH3	0.814	0.07
DOCK7	ABLIM1	0.808
ARHGEF17	NCKIPSD	0.798	0.106
LMO7	COBL	0.796	0.132
ARHGEF17	PPP1R9B	0.796	0.072
NEXN	PHLDB2	0.796
SIPA1	MYO1B	0.796	0.024
NEXN	CDC42	0.794
LIMCH1	RAI14	0.793	0.252
MPRIP	PHLDB2	0.793
LIMCH1	ABLIM1	0.789
SRGAP2	ARHGAP21	0.787	0.198	mutually_exclusive (P60953)
DENND2B	MYL12B	0.785	0.142
SIPA1L1	LRRFIP2	0.785	0.036
SIPA1L1	ARHGAP11A	0.785	0.064
SIPA1	LIMA1	0.781	0.018
PPP1R9A	ABLIM1	0.781
PPP1R9A	COBL	0.781	0.104
PPP1R9A	ARHGAP21	0.781	0.156
SIPA1	LRCH3	0.781	0.038
MYL12B	SIPA1L1	0.78	0.094
DENND2B	TPM3	0.774	0.082
PPP1R9B	PHLDB2	0.774	0.03
TPM1	SIPA1L1	0.774
TPM1	NCKIPSD	0.774
ERC1	TPM4	0.774	0.044
ABLIM1	ARHGAP11A	0.773
COBL	PPP1R9B	0.773	0.064
SIPA1	ARHGAP11A	0.773	0.078
ARHGEF17	NEXN	0.773
ARHGEF17	ARHGAP11A	0.773	0.146
DENND2B	TMOD1	0.773	0.074
SIPA1	TPM4	0.773	0.052
SIPA1	PPP1R9B	0.773	0.06
ITPRID2	ARHGAP11A	0.773	0.102
DENND2B	TPM4	0.773	0.116
ARHGAP11A	COBL	0.773	0.112
SPECC1L	COBL	0.773	0.078
PLEKHG3	COBL	0.773	0.132
ABLIM1	TMOD1	0.773
NEXN	PPP1R12A	0.773
TPM1	DENND2B	0.773
ARHGEF17	COBL	0.773	0.092
ARHGAP11A	PPP1R12A	0.773	0.122
NEXN	COBL	0.773
DENND2B	COBL	0.773	0.132
DENND2B	NEXN	0.773
LRRFIP2	SIPA1L3	0.773	0.038
LIMCH1	DENND2B	0.773	0.142
TPM1	SIPA1	0.773
DENND2B	LRRFIP2	0.773	0.066
LIMCH1	SIPA1	0.773	0.046
NEXN	ABLIM1	0.773
ARHGAP11A	SIPA1L3	0.773	0.122
COBL	TMOD1	0.773	0.076
ARHGAP21	TMOD1	0.773	0.054
SIPA1	LRRFIP2	0.773	0.034
SIPA1	NEXN	0.773
NEXN	SIPA1L3	0.773
TPM1	PHLDB2	0.773
SIPA1	TMOD1	0.773	0.068
NEXN	ITPRID2	0.773
CGN	COBL	0.773	0.084
CGN	ARHGAP11A	0.773	0.094
PPP1R9B	SIPA1L3	0.773	0.06
SIPA1	COBL	0.773	0.062
NEXN	ARHGAP21	0.773
ARHGAP21	PPP1R12A	0.773	0.162
DOCK7	TPM4	0.773
PPP1R12A	PPP1R9B	0.768	0.04
DOCK7	PPP1R12A	0.766
SIPA1L1	PPP1R9B	0.764	0.044
COBL	CDC42	0.764	0.294
NEXN	SIPA1L1	0.764
DOCK7	ARHGAP11A	0.764
SIPA1L1	TMOD1	0.764	0.036
SIPA1	TPM3	0.764	0.0420591133005
DENND2B	MYO1B	0.764	0.098
ARHGEF17	LRRFIP2	0.764	0.074
MYL12B	SIPA1	0.764	0.056
SIPA1L1	COBL	0.764	0.088
DENND2B	PPP1R9B	0.764	0.096
LIMCH1	SIPA1L3	0.762	0.136
TMOD1	PHLDB2	0.762	0.032
TPM3	ARHGAP11A	0.76	0.128
SRGAP2	LRCH3	0.759	0.028
DOCK7	ARHGAP21	0.755
PPP1R12A	MYO1B	0.755	0.114
NCKIPSD	ARHGAP11A	0.752	0.116
ARHGEF17	TPM4	0.751	0.136
COBL	PHLDB2	0.751	0.06
ARHGAP11A	PHLDB2	0.751	0.124
LRRFIP2	PHLDB2	0.751	0.056
SRGAP2	ABLIM1	0.749
LMO7	LRCH3	0.734	0.032
CGN	LRCH3	0.729	0.03
DOCK7	MYO1B	0.729
ABLIM1	PPP1R9B	0.722
SRGAP2	RAI14	0.722	0.116
SRGAP2	PHLDB2	0.72	0.122
NCKIPSD	PPP1R12A	0.717	0.024
TPM4	SIPA1L3	0.716	0.062
TPM1	DOCK7	0.713
MYL12B	DOCK7	0.712
LRRFIP2	CDC42	0.712	0.166550925926
MYO1B	SIPA1L3	0.693	0.092
MPRIP	CGN	0.691
SIPA1	CDC42	0.689	0.22
SPECC1L	SSH1	0.681	0.122
PLEKHG3	SSH1	0.676	0.12
LIMCH1	LRCH3	0.675	0.028
MYL12B	PPP1R12A	0.671	0.154
ITPRID2	COBL	0.669	0.08
SRGAP2	DOCK7	0.658
TPM1	ARHGAP21	0.657
PPP1R12A	CDC42	0.654	0.268
ABLIM1	TPM4	0.65
ARHGEF17	MYO1B	0.644	0.106
RACGAP1	RAI14	0.644	0.134
MPRIP	SIPA1L3	0.642
DOCK7	TPM3	0.641
NCKIPSD	COBL	0.641	0.048
RACGAP1	NEXN	0.641
TPM3	PPP1R12A	0.638	0.074
NCKIPSD	DOCK7	0.634
PPP1R9A	CGN	0.628	0.08
LRCH3	MYO1B	0.627	0.026
MYL12B	PLEKHG3	0.621	0.098
ABLIM1	PPP1R12A	0.618
TPM1	CGN	0.611
NCKIPSD	LRCH3	0.606	0.042
ARHGAP11A	TMOD1	0.6	0.024
ARHGEF17	MYL12B	0.598	0.1
SIPA1L1	LIMA1	0.598	0.048
NCKIPSD	RAI14	0.59	0.046
ABLIM1	MYO1B	0.588
TPM1	SSH1	0.587
SRGAP2	CDC42	0.57	0.252	structurally_consistent (dimer)
TPM4	LRCH3	0.557	0.026
TPM4	PPP1R12A	0.552	0.118
SSH1	LRRFIP2	0.55	0.09
MPRIP	PPP1R9B	0.548
ARHGEF17	LIMCH1	0.548	0.166
RACGAP1	ABLIM1	0.544
ERC1	RACGAP1	0.543	0.116
TPM4	ARHGAP21	0.541	0.06
TPM4	MYO1B	0.533	0.062
NCKIPSD	MYO1B	0.524	0.022
LRCH3	SIPA1L3	0.522	0.038
CDC42	LIMA1	0.521	0.338
TPM3	MYO1B	0.515	0.042
MYL12B	ARHGAP11A	0.513	0.142
SSH1	MYO1B	0.512	0.088
ARHGAP21	MYO1B	0.511	0.148
CGN	TPM3	0.505	0.096
ABLIM1	LRCH3	0.493
ARHGEF17	LIMA1	0.489	0.084
LIMA1	PHLDB2	0.48	0.026
SRGAP2	TPM1	0.475
RACGAP1	NCKIPSD	0.467	0.05
ERC1	COBL	0.456	0.1
MPRIP	LRCH3	0.453
ARHGAP21	SSH1	0.449	0.124
RAI14	CDC42	0.448	0.277333333333
ERC1	ARHGAP21	0.445	0.112
TPM3	LRCH3	0.44	0.022
MYL12B	SSH1	0.437	0.108
LRCH3	PHLDB2	0.437	0.018
TPM3	CDC42	0.432	0.15
TPM4	PHLDB2	0.426	0.038
MYL12B	CDC42	0.413	0.319
ITPRID2	TPM3	0.411	0.04
SIPA1L1	LRCH3	0.41	0.048
SIPA1L1	TPM4	0.397	0.068
SRGAP2	LMO7	0.389	0.148
ARHGAP11A	LRCH3	0.383	0.054
RACGAP1	COBL	0.383	0.18277037037
LMO7	CDC42	0.381	0.37
LIMCH1	DOCK7	0.379
TPM3	PHLDB2	0.376	0.048
DOCK7	LMO7	0.372
ARHGEF17	TPM3	0.365	0.116
RACGAP1	LIMCH1	0.361	0.062
CDC42	SIPA1L3	0.359	0.232
TPM4	COBL	0.357	0.112
NCKIPSD	TPM3	0.352	0.042
ABLIM1	CDC42	0.351
NCKIPSD	PLEKHG3	0.349	0.108
MPRIP	SIPA1L1	0.348
ARHGAP21	PPP1R9B	0.345	0.146
RAI14	SSH1	0.328	0.124
TPM1	LRCH3	0.324
RACGAP1	CGN	0.324	0.058
SRGAP2	ITPRID2	0.319	0.068
SSH1	LRCH3	0.316	0.074
CGN	CDC42	0.311	0.166333333333
LMO7	PPP1R12A	0.307	0.192
MYL12B	COBL	0.305	0.036
ITPRID2	TPM4	0.299	0.056
SRGAP2	SPECC1L	0.297	0.154
LMO7	PHLDB2	0.297	0.068
DENND2B	PPP1R9A	0.288	0.094
SIPA1	PPP1R9A	0.288	0.046
RACGAP1	PPP1R9B	0.288	0.054
PPP1R9A	DOCK7	0.285
MPRIP	LMO7	0.276
ERC1	DOCK7	0.276
TPM3	COBL	0.276	0.026
LIMCH1	MPRIP	0.275
ITPRID2	LIMA1	0.272	0.028
MYL12B	PPP1R9A	0.269	0.076
ERC1	ITPRID2	0.261	0.042
TPM3	SIPA1L3	0.26	0.0336
CGN	SSH1	0.259	0.104
SRGAP2	RACGAP1	0.258	0.128
MYL12B	SIPA1L3	0.253	0.06
SRGAP2	MPRIP	0.25
TPM4	CDC42	0.249	0.228
MPRIP	SIPA1	0.246
ERC1	RAI14	0.243	0.088
MYL12B	PHLDB2	0.241	0.082
RACGAP1	LIMA1	0.238	0.102
DENND2B	LRCH3	0.236	0.116
DENND2B	SSH1	0.232	0.082
MYL12B	ARHGAP21	0.231	0.084
SRGAP2	LIMCH1	0.231	0.128
ITPRID2	TMOD1	0.221	0.04
ERC1	SPECC1L	0.218	0.078
SRGAP2	ARHGEF17	0.2	0.14	mutually_exclusive (P60953)
RACGAP1	DOCK7	0.19
SRGAP2	TPM3	0.189	0.132
RACGAP1	MYO1B	0.188	0.076
PPP1R9A	LRCH3	0.186	0.05
SRGAP2	PPP1R12A	0.183	0.122
LIMCH1	PPP1R12A	0.179	0.09
MPRIP	DOCK7	0.171
PPP1R9A	TPM4	0.169	0.08
ERC1	TPM1	0.167
PPP1R9A	MYO1B	0.16	0.08
RACGAP1	TPM1	0.152
PPP1R9A	TPM3	0.151	0.104
ITPRID2	LRCH3	0.15	0.028
PPP1R9A	ITPRID2	0.149	0.092
PPP1R9A	PHLDB2	0.149	0.082
ERC1	TMOD1	0.149	0.054
RACGAP1	ARHGAP11A	0.149	0.214
ERC1	NEXN	0.149
RACGAP1	LRRFIP2	0.149	0.112
RACGAP1	ARHGEF17	0.147	0.208
MYL12B	LMO7	0.143	0.184
SSH1	ARHGAP11A	0.133	0.094
DENND2B	LMO7	0.132	0.076
LRCH3	CDC42	0.127	0.0945509259259
PPP1R9A	LMO7	0.125	0.112
ABLIM1	SSH1	0.122
LIMCH1	PPP1R9A	0.118	0.178
ERC1	LRCH3	0.115	0.052
TPM1	SIPA1L3	0.115
RACGAP1	LRCH3	0.11	0.032
PPP1R9A	SSH1	0.107	0.106
DOCK7	SSH1	0.096
RACGAP1	TPM3	0.094	0.054
RACGAP1	TPM4	0.092	0.14
ERC1	MYL12B	0.089	0.086
RACGAP1	MPRIP	0.088
RACGAP1	SIPA1L1	0.086	0.09
MPRIP	SSH1	0.084
SRGAP2	PLEKHG3	0.08	0.12
MYO1B	CDC42	0.077	0.232
MPRIP	TPM3	0.073
SRGAP2	LRRFIP2	0.071	0.048
MYL12B	ITPRID2	0.065	0.082
RACGAP1	MYL12B	0.064	0.258
ERC1	TPM3	0.064	0.06
ERC1	ARHGAP11A	0.063	0.16
SRGAP2	NEXN	0.063
SRGAP2	ARHGAP11A	0.063	0.15
ERC1	PLEKHG3	0.059	0.146
SIPA1	SSH1	0.058	0.08
SRGAP2	COBL	0.05	0.162
SSH1	COBL	0.049	0.092
PPP1R9A	SIPA1L1	0.049	0.074
SRGAP2	TMOD1	0.049	0.078
SRGAP2	LIMA1	0.047	0.036
PPP1R9A	CDC42	0.045	0.26
TPM3	SSH1	0.045	0.13
ERC1	LRRFIP2	0.044	0.072
SRGAP2	TPM4	0.043	0.132
ARHGEF17	LRCH3	0.043	0.046
LMO7	MYO1B	0.039	0.218
ARHGEF17	PPP1R9A	0.039	0.114
ARHGEF17	CDC42	0.039	0.333739130435	structurally_consistent (dimer)
ERC1	PPP1R12A	0.036	0.066
PPP1R9A	SIPA1L3	0.034	0.116
CGN	MYO1B	0.034	0.108
ERC1	NCKIPSD	0.032	0.03
ERC1	ARHGEF17	0.028	0.248
ERC1	LMO7	0.028	0.118
RACGAP1	TMOD1	0.027	0.086
ERC1	MYO1B	0.027	0.05
SSH1	CDC42	0.027	0.261531610338
NCKIPSD	PPP1R9A	0.025	0.06
DOCK7	CDC42	0.023
CDC42	PHLDB2	0.022	0.238
SIPA1L1	SSH1	0.019	0.046
SSH1	PHLDB2	0.018	0.102
ERC1	LIMA1	0.016	0.036
ERC1	LIMCH1	0.016	0.07
SRGAP2	PPP1R9B	0.016	0.048
MPRIP	MYL12B	0.015
SSH1	SIPA1L3	0.015	0.108
SIPA1L1	CDC42	0.013	0.0982580645161
RACGAP1	CDC42	0.013	0.498928571429
SRGAP2	SSH1	0.011	0.118842105263
ERC1	MPRIP	0.01
ERC1	PPP1R9B	0.008	0.058
ERC1	CDC42	0.008	0.220444444444
ERC1	SSH1	0.008	0.108
ITPRID2	SSH1	0.006	0.052
SRGAP2	MYO1B	0.006	0.062
MYO1B	PHLDB2	0.006	0.02
SIPA1L1	MYO1B	0.005	0.046
MPRIP	CDC42	0.004
RACGAP1	SSH1	0.004	0.20877037037
SRGAP2	MYL12B	0.004	0.054
SSH1	PPP1R12A	0.003	0.146
MPRIP	NCKIPSD	0.003

Related Complexes

Genename	Complexes
CGN	huMAP3_05977.1 huMAP3_06763.1 huMAP3_08205.1 huMAP3_09542.1 huMAP3_13918.1
TMOD1	huMAP3_07337.1 huMAP3_07928.1 huMAP3_09542.1
SIPA1L3	huMAP3_08222.1 huMAP3_09542.1
SIPA1L1	huMAP3_05977.1 huMAP3_08222.1 huMAP3_09542.1
MYO1B	huMAP3_07337.1 huMAP3_08445.1 huMAP3_09542.1
MPRIP	huMAP3_01198.1 huMAP3_05613.1 huMAP3_06763.1 huMAP3_08205.1 huMAP3_09542.1
CDC42	huMAP3_08205.1 huMAP3_09542.1 huMAP3_11311.1
TPM4	huMAP3_06153.1 huMAP3_06763.1 huMAP3_08205.1 huMAP3_09542.1
DOCK7	huMAP3_05977.1 huMAP3_06763.1 huMAP3_08205.1 huMAP3_09542.1 huMAP3_13571.1
LMO7	huMAP3_05977.1 huMAP3_06763.1 huMAP3_08205.1 huMAP3_09542.1
PPP1R9A	huMAP3_03989.1 huMAP3_06763.1 huMAP3_08205.1 huMAP3_09542.1 huMAP3_14504.1
NCKIPSD	huMAP3_02986.1 huMAP3_03325.1 huMAP3_08945.1 huMAP3_09542.1 huMAP3_10301.1 huMAP3_13447.1
COBL	huMAP3_06763.1 huMAP3_08205.1 huMAP3_09542.1
ERC1	huMAP3_00524.1 huMAP3_08222.1 huMAP3_09542.1 huMAP3_11531.1 huMAP3_14446.1
TPM1	huMAP3_01231.1 huMAP3_06153.1 huMAP3_08088.1 huMAP3_08205.1 huMAP3_09542.1
ARHGAP21	huMAP3_06445.1 huMAP3_07753.1 huMAP3_09542.1
ITPRID2	huMAP3_05613.1 huMAP3_07657.1 huMAP3_09542.1
RAI14	huMAP3_05613.1 huMAP3_08205.1 huMAP3_09542.1
LRRFIP2	huMAP3_07337.1 huMAP3_07816.1 huMAP3_09542.1
ARHGAP11A	huMAP3_06763.1 huMAP3_08205.1 huMAP3_09542.1
SPECC1L	huMAP3_03989.1 huMAP3_05613.1 huMAP3_06763.1 huMAP3_08205.1 huMAP3_09542.1
PLEKHG3	huMAP3_05613.1 huMAP3_06763.1 huMAP3_09542.1
DENND2B	huMAP3_02130.1 huMAP3_05613.1 huMAP3_08222.1 huMAP3_09542.1 huMAP3_14132.1
ABLIM1	huMAP3_05977.1 huMAP3_08205.1 huMAP3_09542.1 huMAP3_11784.1
MYL12B	huMAP3_02370.1 huMAP3_06098.1 huMAP3_06531.1 huMAP3_08039.1 huMAP3_09542.1 huMAP3_10270.1
LIMA1	huMAP3_09542.1 huMAP3_11813.1
PPP1R9B	huMAP3_07337.1 huMAP3_07928.1 huMAP3_09542.1
SSH1	huMAP3_06725.1 huMAP3_08504.1 huMAP3_09542.1 huMAP3_13933.1
PPP1R12A	huMAP3_06763.1 huMAP3_08205.1 huMAP3_09542.1 huMAP3_12994.1
TPM3	huMAP3_06153.1 huMAP3_07595.1 huMAP3_08088.1 huMAP3_09542.1
RACGAP1	huMAP3_00688.1 huMAP3_02549.1 huMAP3_07024.1 huMAP3_07753.1 huMAP3_09542.1 huMAP3_11326.1 huMAP3_13310.1
ARHGEF17	huMAP3_00758.1 huMAP3_03989.1 huMAP3_05613.1 huMAP3_08205.1 huMAP3_09542.1
LRCH3	huMAP3_06763.1 huMAP3_08205.1 huMAP3_09542.1 huMAP3_13571.1
LIMCH1	huMAP3_01066.1 huMAP3_03460.1 huMAP3_07928.1 huMAP3_09542.1 huMAP3_10034.1
SIPA1	huMAP3_02549.1 huMAP3_04050.1 huMAP3_05977.1 huMAP3_08222.1 huMAP3_09542.1 huMAP3_10496.1 huMAP3_14132.1
PHLDB2	huMAP3_09542.1
NEXN	huMAP3_05153.1 huMAP3_06763.1 huMAP3_07928.1 huMAP3_09542.1 huMAP3_13792.1
SRGAP2	huMAP3_00235.1 huMAP3_02549.1 huMAP3_04537.1 huMAP3_05977.1 huMAP3_07838.1 huMAP3_08222.1 huMAP3_09542.1 huMAP3_09810.1 huMAP3_10496.1 huMAP3_10808.1 huMAP3_11531.1 huMAP3_12897.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_09542.1

Complex Portal: CPX-12142