hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09543.1
Complex Portal: CPX-22665
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HNRNPA2B1 | Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2/B1) | 5 | UniProt NCBI |
| HNRNPA0 | Heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0) | 5 | UniProt NCBI |
| HNRNPH3 | Heterogeneous nuclear ribonucleoprotein H3 (hnRNP H3) (Heterogeneous nuclear ribonucleoprotein 2H9) (hnRNP 2H9) | 5 | UniProt NCBI |
| HNRNPAB | Heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) (APOBEC1-binding protein 1) (ABBP-1) | 5 | UniProt NCBI |
| HNRNPA3 | Heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3) | 5 | UniProt NCBI |
| HNRNPD | Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1) | 5 | UniProt NCBI |
| RNASE1 | Ribonuclease pancreatic (EC 4.6.1.18) (HP-RNase) (RIB-1) (RNase UpI-1) (Ribonuclease 1) (RNase 1) (Ribonuclease A) (RNase A) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0016071 | 0.000979013104412 | 0.857142857143 | HNRNPAB HNRNPA2B1 HNRNPA0 HNRNPD HNRNPH3 HNRNPA3 | mRNA metabolic process |
| WP:WP411 | 0.00175582243967 | 0.428571428571 | HNRNPD HNRNPA2B1 HNRNPAB | mRNA processing |
| HPA:0461492 | 0.00668955109807 | 0.428571428571 | HNRNPA3 HNRNPA2B1 HNRNPA0 | skin 1; vascular mural cells[>=Medium] |
| HPA:0550053 | 0.00742299915125 | 0.857142857143 | RNASE1 HNRNPAB HNRNPA2B1 HNRNPA0 HNRNPD HNRNPA3 | stomach 2; glandular cells[High] |
| GO:1905663 | 0.00983221512175 | 0.285714285714 | HNRNPD HNRNPA2B1 | positive regulation of telomerase RNA reverse transcriptase activity |
| HPA:0471472 | 0.00999083320945 | 0.571428571429 | HNRNPA3 HNRNPD HNRNPA2B1 HNRNPA0 | skin 2; lymphocytes[>=Medium] |
| HPA:0080123 | 0.0105779971796 | 0.571428571429 | HNRNPA3 HNRNPD HNRNPA2B1 HNRNPAB | caudate; glial cells[High] |
| HPA:0471462 | 0.0109149667832 | 0.571428571429 | HNRNPA3 HNRNPD HNRNPA2B1 HNRNPA0 | skin 2; langerhans cells[>=Medium] |
| HPA:0471412 | 0.0121199564265 | 0.571428571429 | HNRNPA3 HNRNPD HNRNPA2B1 HNRNPA0 | skin 2; cells in spinous layer[>=Medium] |
| HPA:0570783 | 0.0124922608346 | 0.571428571429 | HNRNPA3 HNRNPD HNRNPA2B1 HNRNPA0 | testis; preleptotene spermatocytes[High] |
| HPA:0461491 | 0.0139394045602 | 0.428571428571 | HNRNPA3 HNRNPA2B1 HNRNPA0 | skin 1; vascular mural cells[>=Low] |
| HPA:0460181 | 0.0141484242464 | 0.571428571429 | HNRNPA3 HNRNPD HNRNPA2B1 HNRNPA0 | skin 1; cells in granular layer[>=Low] |
| HPA:0461461 | 0.0156029483059 | 0.571428571429 | HNRNPA3 HNRNPD HNRNPA2B1 HNRNPA0 | skin 1; langerhans cells[>=Low] |
| REAC:R-HSA-72163 | 0.0166902174261 | 0.428571428571 | HNRNPD HNRNPA2B1 HNRNPA3 | mRNA Splicing - Major Pathway |
| REAC:R-HSA-72172 | 0.0184779747348 | 0.428571428571 | HNRNPD HNRNPA2B1 HNRNPA3 | mRNA Splicing |
| HPA:0461411 | 0.0195602838988 | 0.571428571429 | HNRNPA3 HNRNPD HNRNPA2B1 HNRNPA0 | skin 1; cells in spinous layer[>=Low] |
| HPA:0530713 | 0.0199822213844 | 0.571428571429 | HNRNPA3 HNRNPD HNRNPA2B1 HNRNPAB | spleen; cells in red pulp[High] |
| HPA:0471461 | 0.0215116986118 | 0.571428571429 | HNRNPA3 HNRNPD HNRNPA2B1 HNRNPA0 | skin 2; langerhans cells[>=Low] |
| HPA:0381193 | 0.0217996876337 | 0.428571428571 | HNRNPD HNRNPA2B1 HNRNPA0 | placenta; cytotrophoblasts[High] |
| HPA:0471471 | 0.0231252895436 | 0.571428571429 | HNRNPA3 HNRNPD HNRNPA2B1 HNRNPA0 | skin 2; lymphocytes[>=Low] |
| HPA:0471442 | 0.0260953354628 | 0.571428571429 | HNRNPA3 HNRNPD HNRNPA2B1 HNRNPA0 | skin 2; fibrohistiocytic cells[>=Medium] |
| HPA:0291163 | 0.0274488391455 | 0.428571428571 | HNRNPA3 HNRNPA2B1 HNRNPAB | liver; cholangiocytes[High] |
| GO:1905661 | 0.0294899169624 | 0.285714285714 | HNRNPD HNRNPA2B1 | regulation of telomerase RNA reverse transcriptase activity |
| HPA:0570763 | 0.0307687507812 | 0.571428571429 | HNRNPA3 HNRNPD HNRNPA2B1 HNRNPA0 | testis; pachytene spermatocytes[High] |
| HPA:0471411 | 0.0316529118298 | 0.571428571429 | HNRNPA3 HNRNPD HNRNPA2B1 HNRNPA0 | skin 2; cells in spinous layer[>=Low] |
| HPA:0090193 | 0.0319517165126 | 0.571428571429 | HNRNPA3 HNRNPD HNRNPA2B1 HNRNPAB | cerebellum; cells in molecular layer[High] |
| HPA:0570793 | 0.0331675907289 | 0.571428571429 | HNRNPA3 HNRNPD HNRNPA2B1 HNRNPA0 | testis; round or early spermatids[High] |
| HPA:0461391 | 0.03394447348 | 0.571428571429 | HNRNPA3 HNRNPD HNRNPA2B1 HNRNPA0 | skin 1; cells in basal layer[>=Low] |
| HPA:0381213 | 0.035588561295 | 0.428571428571 | HNRNPD HNRNPA2B1 HNRNPA0 | placenta; syncytiotrophoblasts - cell body[High] |
| HPA:0100133 | 0.0357100891892 | 0.714285714286 | HNRNPAB HNRNPD HNRNPA2B1 HNRNPA3 HNRNPA0 | cerebral cortex; neuronal cells[High] |
| REAC:R-HSA-72203 | 0.0418111738628 | 0.428571428571 | HNRNPD HNRNPA2B1 HNRNPA3 | Processing of Capped Intron-Containing Pre-mRNA |
| HPA:0350473 | 0.0458544730906 | 0.714285714286 | HNRNPA3 HNRNPD HNRNPA2B1 RNASE1 HNRNPAB | pancreas; exocrine glandular cells[High] |
| HPA:0471391 | 0.0468639632052 | 0.571428571429 | HNRNPA3 HNRNPD HNRNPA2B1 HNRNPA0 | skin 2; cells in basal layer[>=Low] |
| CORUM:7337 | 0.0499958217778 | 0.142857142857 | HNRNPD | AUF1(p45)-ZFP36 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| HNRNPD | HNRNPAB | 0.993 | 0.67 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () Malo gupta_WMM fraction boldt_WMM treiber_WMM | |
| HNRNPA3 | HNRNPAB | 0.991 | 0.586 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM fraction treiber_WMM | |
| HNRNPA3 | HNRNPH3 | 0.988 | 0.79 | hein_WMM bioplex_WMM Guru bioplex3_WMM youn_WMM hein () gupta_WMM fraction treiber_WMM | |
| HNRNPA3 | HNRNPA0 | 0.987 | 0.88 | hein_WMM bioplex_WMM bioplex3_WMM hein () gupta_WMM fraction treiber_WMM | |
| HNRNPA3 | HNRNPA2B1 | 0.985 | 0.94 | hein_WMM bioplex_WMM bioplex3_WMM hein () gupta_WMM treiber_WMM | |
| HNRNPA0 | HNRNPAB | 0.981 | 0.442 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM fraction treiber_WMM | |
| HNRNPD | HNRNPA3 | 0.972 | 0.86 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM | |
| HNRNPA3 | RNASE1 | 0.968 | bioplex3_HEK293 bioplex () bioplex3_WMM bioplex3_HCT116 | ||
| HNRNPD | HNRNPA0 | 0.954 | 0.59 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM WMM_only treiber_WMM | |
| HNRNPD | HNRNPA2B1 | 0.951 | 0.81 | hein_WMM bioplex_WMM bioplex3_WMM boldt hein () gupta_WMM fraction boldt_WMM treiber_WMM | |
| HNRNPA0 | HNRNPH3 | 0.951 | 0.624 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM WMM_only treiber_WMM | |
| HNRNPH3 | HNRNPA2B1 | 0.935 | 0.928 | hein_WMM bioplex_WMM Guru bioplex3_WMM gupta_WMM fraction treiber_WMM | |
| HNRNPAB | HNRNPA2B1 | 0.86 | 0.792 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM fraction boldt_WMM treiber_WMM | |
| HNRNPH3 | HNRNPAB | 0.858 | 0.488 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM | |
| HNRNPA0 | HNRNPA2B1 | 0.833 | 0.866 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM WMM_only treiber_WMM | |
| HNRNPD | HNRNPH3 | 0.796 | 0.524 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM | |
| HNRNPH3 | RNASE1 | 0.652 | bioplex3_HEK293 bioplex () bioplex3_WMM bioplex3_HCT116 | ||
| RNASE1 | HNRNPA2B1 | 0.572 | bioplex3_HEK293 bioplex () bioplex3_WMM bioplex3_HCT116 | ||
| HNRNPAB | RNASE1 | 0.109 | bioplex3_HEK293 bioplex () bioplex3_WMM bioplex3_HCT116 | ||
| HNRNPA0 | RNASE1 | 0.021 | bioplex3_HEK293 bioplex () bioplex3_WMM bioplex3_HCT116 | ||
| HNRNPD | RNASE1 | 0.02 | bioplex3_HEK293 bioplex () bioplex3_HCT116 |
Related Complexes