hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_09563.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MACF1 | Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) | 5 | UniProt NCBI |
| PGGT1B | Geranylgeranyl transferase type-1 subunit beta (EC 2.5.1.59) (Geranylgeranyl transferase type I subunit beta) (GGTase-I-beta) (Type I protein geranyl-geranyltransferase subunit beta) | 5 | UniProt NCBI |
| AMMECR1L | AMMECR1-like protein | 2 | UniProt NCBI |
| FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0004662 | 0.0028092043205 | 0.5 | FNTA PGGT1B | CAAX-protein geranylgeranyltransferase activity |
| GO:0005953 | 0.0028092043205 | 0.5 | FNTA PGGT1B | CAAX-protein geranylgeranyltransferase complex |
| GO:0004661 | 0.0280843539964 | 0.5 | FNTA PGGT1B | protein geranylgeranyltransferase activity |
| GO:0008318 | 0.042122686785 | 0.5 | FNTA PGGT1B | protein prenyltransferase activity |
| CORUM:419 | 0.049938562206 | 0.25 | FNTA | Farnesyltransferase |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| FNTA | PGGT1B | 0.999 | 0.34 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction |
| AMMECR1L | PGGT1B | 0.998 | 0.038 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| FNTA | AMMECR1L | 0.996 | 0.08 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| MACF1 | AMMECR1L | 0.953 | 0.032 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| MACF1 | PGGT1B | 0.251 | 0.038 | bioplex_WMM bioplex3_WMM WMM_only |
| FNTA | MACF1 | 0.023 | 0.028 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes