hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09579.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CORO1A | Coronin-1A (Coronin-like protein A) (Clipin-A) (Coronin-like protein p57) (Tryptophan aspartate-containing coat protein) (TACO) | 5 | UniProt NCBI |
| CFL1 | Cofilin-1 (18 kDa phosphoprotein) (p18) (Cofilin, non-muscle isoform) | 5 | UniProt NCBI |
| CORO1B | Coronin-1B (Coronin-2) | 5 | UniProt NCBI |
| CORO6 | Coronin-6 (Coronin-like protein E) (Clipin-E) | 4 | UniProt NCBI |
| AFAP1 | Actin filament-associated protein 1 (110 kDa actin filament-associated protein) (AFAP-110) | 5 | UniProt NCBI |
| SYNPO | Synaptopodin | 5 | UniProt NCBI |
| DSTN | Destrin (Actin-depolymerizing factor) (ADF) | 5 | UniProt NCBI |
| CFL2 | Cofilin-2 (Cofilin, muscle isoform) | 5 | UniProt NCBI |
| CORO1C | Coronin-1C (Coronin-3) (hCRNN4) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0003779 | 6.4762284631e-09 | 0.888888888889 | SYNPO CORO1C CORO1B DSTN CORO1A CFL1 CFL2 CORO6 | actin binding |
| GO:0007015 | 3.24754875201e-08 | 0.888888888889 | SYNPO CORO1C CORO1B DSTN CORO1A CFL1 CFL2 CORO6 | actin filament organization |
| GO:0051015 | 4.30895189983e-08 | 0.777777777778 | CORO1C CORO1B DSTN CORO1A CFL1 CFL2 CORO6 | actin filament binding |
| GO:0015629 | 7.8480619513e-08 | 0.888888888889 | SYNPO CORO1C CORO1B DSTN CORO1A CFL1 CFL2 AFAP1 | actin cytoskeleton |
| GO:0030036 | 1.25705502396e-06 | 0.888888888889 | SYNPO CORO1C CORO1B DSTN CORO1A CFL1 CFL2 CORO6 | actin cytoskeleton organization |
| GO:0030029 | 3.00527645706e-06 | 0.888888888889 | SYNPO CORO1C CORO1B DSTN CORO1A CFL1 CFL2 CORO6 | actin filament-based process |
| GO:0097435 | 3.57637043496e-06 | 0.888888888889 | SYNPO CORO1C CORO1B DSTN CORO1A CFL1 CFL2 CORO6 | supramolecular fiber organization |
| GO:0030043 | 8.07408345042e-06 | 0.333333333333 | CFL1 DSTN CFL2 | actin filament fragmentation |
| GO:0008092 | 1.2869821495e-05 | 0.888888888889 | SYNPO CORO1C CORO1B DSTN CORO1A CFL1 CFL2 CORO6 | cytoskeletal protein binding |
| GO:0007010 | 0.000428673884053 | 0.888888888889 | SYNPO CORO1C CORO1B DSTN CORO1A CFL1 CFL2 CORO6 | cytoskeleton organization |
| GO:0051014 | 0.00450341440411 | 0.333333333333 | CFL1 DSTN CFL2 | actin filament severing |
| GO:0005856 | 0.00564626210456 | 0.888888888889 | SYNPO CORO1C CORO1B DSTN CORO1A CFL1 CFL2 AFAP1 | cytoskeleton |
| WP:WP524 | 0.016080037976 | 0.222222222222 | CFL1 CFL2 | G13 signaling pathway |
| KEGG:05133 | 0.0286338067835 | 0.222222222222 | CFL1 CFL2 | Pertussis |
| GO:0044877 | 0.0299078251694 | 0.777777777778 | CORO1C CORO1B DSTN CORO1A CFL1 CFL2 CORO6 | protein-containing complex binding |
| GO:0030027 | 0.0310808183133 | 0.444444444444 | CORO1C CFL1 CORO1A CORO1B | lamellipodium |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CORO1B | CORO1A | 0.999 | 0.104 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM |
| CORO6 | CORO1A | 0.999 | 0.12 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| CORO1B | CORO1C | 0.999 | 0.188 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 gupta_WMM fraction boldt_WMM treiber_WMM |
| CFL2 | CFL1 | 0.999 | 0.918 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM WMM_only |
| CFL2 | CORO1C | 0.999 | 0.178 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM |
| CORO6 | CORO1C | 0.999 | 0.084 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| CORO1A | CORO1C | 0.998 | 0.08 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM treiber_WMM |
| CORO6 | CORO1B | 0.998 | 0.148 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| DSTN | AFAP1 | 0.993 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| CFL1 | DSTN | 0.983 | 0.572 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction treiber_WMM |
| DSTN | CORO1C | 0.981 | 0.304 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM |
| CFL2 | DSTN | 0.979 | 0.476 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM WMM_only |
| CFL1 | CORO1C | 0.965 | 0.184 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM |
| SYNPO | CORO1C | 0.963 | hein_WMM hein () | |
| CORO1C | AFAP1 | 0.963 | hein_WMM hein () | |
| CFL1 | AFAP1 | 0.952 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| CORO1B | CFL2 | 0.938 | 0.17 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| SYNPO | DSTN | 0.781 | hein_WMM WMM_only | |
| CORO1B | AFAP1 | 0.773 | hein_WMM WMM_only | |
| CORO1B | SYNPO | 0.773 | hein_WMM WMM_only | |
| CFL2 | AFAP1 | 0.773 | hein_WMM WMM_only | |
| SYNPO | AFAP1 | 0.773 | hein_WMM WMM_only | |
| SYNPO | CFL1 | 0.764 | hein_WMM WMM_only | |
| CORO1B | DSTN | 0.758 | 0.19 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| CORO1B | CFL1 | 0.74 | 0.146 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| SYNPO | CFL2 | 0.351 | hein_WMM WMM_only | |
| CORO1A | DSTN | 0.065 | 0.07 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| CORO6 | DSTN | 0.062 | 0.058 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| CORO1A | CFL2 | 0.019 | 0.104 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| CORO6 | CFL2 | 0.019 | 0.12 | bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only |
| CORO6 | CFL1 | 0.006 | 0.2 | bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only |
| CORO1A | CFL1 | 0.003 | 0.396 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
Related Complexes