hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_09585.1

Complex Portal: CPX-19688

Confidence: Moderate High

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Genename	Protein Name	Uniprot Annotation Score	Links
KIF3A	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A)	5	UniProt NCBI
KIF3B	Kinesin-like protein KIF3B (HH0048) (Microtubule plus end-directed kinesin motor 3B) [Cleaved into: Kinesin-like protein KIF3B, N-terminally processed]	5	UniProt NCBI
KIF3C	Kinesin-like protein KIF3C	5	UniProt NCBI
KIFAP3	Kinesin-associated protein 3 (KAP-3) (KAP3) (Smg GDS-associated protein)	5	UniProt NCBI
LYG1	Lysozyme g-like protein 1 (EC 3.2.1.-)	3	UniProt NCBI
NCKAP5	Nck-associated protein 5 (NAP-5) (Peripheral clock protein)	4	UniProt NCBI

Showing 1 to 6 of 6 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-5620924	3.60757054426e-07	0.666666666667	KIFAP3 KIF3A KIF3B KIF3C	Intraflagellar transport
REAC:R-HSA-983189	4.56391388507e-07	0.666666666667	KIFAP3 KIF3A KIF3B KIF3C	Kinesins
GO:0016939	1.92240082153e-06	0.5	KIFAP3 KIF3B KIF3A	kinesin II complex
REAC:R-HSA-6811434	4.19553514217e-06	0.666666666667	KIFAP3 KIF3A KIF3B KIF3C	COPI-dependent Golgi-to-ER retrograde traffic
REAC:R-HSA-2132295	1.06250680796e-05	0.666666666667	KIFAP3 KIF3A KIF3B KIF3C	MHC class II antigen presentation
KEGG:04814	1.11014436202e-05	0.666666666667	KIFAP3 KIF3A KIF3B KIF3C	Motor proteins
REAC:R-HSA-8856688	1.43305165125e-05	0.666666666667	KIFAP3 KIF3A KIF3B KIF3C	Golgi-to-ER retrograde transport
GO:0072383	1.92180881975e-05	0.5	KIFAP3 KIF3B KIF3A	plus-end-directed vesicle transport along microtubule
GO:0005871	2.5973152006e-05	0.666666666667	KIFAP3 KIF3A KIF3B KIF3C	kinesin complex
REAC:R-HSA-983231	3.47573058056e-05	0.666666666667	KIFAP3 KIF3A KIF3B KIF3C	Factors involved in megakaryocyte development and platelet production

Showing 1 to 10 of 30 entries

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Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
KIFAP3	KIF3A	1.0	0.47	structurally_consistent (dimer)	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () Malo bioplex3_HCT116 gupta_WMM fraction boldt_WMM
KIF3B	KIF3A	1.0	0.448	mutually_exclusive (Q92845)	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 gupta_WMM boldt_WMM
KIFAP3	KIF3B	1.0	0.376	structurally_consistent (dimer)	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 gupta_WMM boldt_WMM
KIFAP3	KIF3C	0.997	0.116	structurally_consistent (dimer)	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt hein () bioplex3_HCT116 boldt_WMM
KIF3C	KIF3A	0.994	0.202	mutually_exclusive (Q92845)	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt hein () boldt_WMM
LYG1	KIF3A	0.983			bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
KIF3C	KIF3B	0.983	0.178	mutually_exclusive (Q92845)	bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only
KIF3C	NCKAP5	0.972		mutually_exclusive (Q92845)	bioplex3_HEK293 bioplex3_WMM WMM_only
KIFAP3	NCKAP5	0.972		structurally_consistent (dimer)	bioplex3_HEK293 bioplex3_WMM WMM_only
NCKAP5	KIF3B	0.884		mutually_exclusive (Q92845)	bioplex3_HEK293 bioplex3_WMM WMM_only

Showing 1 to 10 of 13 entries

Related Complexes

Genename	Complexes
KIFAP3	huMAP3_02461.1 huMAP3_07978.1 huMAP3_09585.1 huMAP3_10422.1 huMAP3_12337.1 huMAP3_13393.1
KIF3C	huMAP3_02461.1 huMAP3_07978.1 huMAP3_09585.1 huMAP3_10422.1 huMAP3_12337.1 huMAP3_13393.1
KIF3A	huMAP3_02614.1 huMAP3_07978.1 huMAP3_09585.1 huMAP3_10422.1 huMAP3_12337.1 huMAP3_12578.1 huMAP3_13393.1
KIF3B	huMAP3_02461.1 huMAP3_07978.1 huMAP3_09585.1 huMAP3_10422.1 huMAP3_12337.1 huMAP3_13393.1
LYG1	huMAP3_02614.1 huMAP3_07978.1 huMAP3_09585.1 huMAP3_10422.1 huMAP3_12337.1 huMAP3_12578.1 huMAP3_13393.1
NCKAP5	huMAP3_02461.1 huMAP3_05389.1 huMAP3_09585.1 huMAP3_10422.1 huMAP3_12337.1 huMAP3_13393.1