hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_09587.1

Complex Portal: CPX-25404

Confidence: Moderate High

Genename	Protein Name	Uniprot Annotation Score	Links
SRSF7	Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7)	5	UniProt NCBI
CLK2	Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)	5	UniProt NCBI
MKRN1	E3 ubiquitin-protein ligase makorin-1 (EC 2.3.2.27) (RING finger protein 61) (RING-type E3 ubiquitin transferase makorin-1)	5	UniProt NCBI
SRSF8	Serine/arginine-rich splicing factor 8 (Pre-mRNA-splicing factor SRP46) (Splicing factor SRp46) (Splicing factor, arginine/serine-rich 2B)	5	UniProt NCBI
NCBP1	Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit)	5	UniProt NCBI
CLK3	Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)	5	UniProt NCBI
SPEN	Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog)	5	UniProt NCBI
TRA2A	Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)	5	UniProt NCBI
CLK1	Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)	5	UniProt NCBI
YTHDC1	YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B)	5	UniProt NCBI
SRSF12	Serine/arginine-rich splicing factor 12 (35 kDa SR repressor protein) (SRrp35) (Splicing factor, arginine/serine-rich 13B) (Splicing factor, arginine/serine-rich 19)	5	UniProt NCBI
APOBEC3F	DNA dC->dU-editing enzyme APOBEC-3F (EC 3.5.4.38) (Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F) (A3F)	5	UniProt NCBI
LUC7L2	Putative RNA-binding protein Luc7-like 2	5	UniProt NCBI
PPIG	Peptidyl-prolyl cis-trans isomerase G (PPIase G) (Peptidyl-prolyl isomerase G) (EC 5.2.1.8) (CASP10) (Clk-associating RS-cyclophilin) (CARS-Cyp) (CARS-cyclophilin) (SR-cyclophilin) (SR-cyp) (SRcyp) (Cyclophilin G) (Rotamase G)	5	UniProt NCBI
RBBP6	E3 ubiquitin-protein ligase RBBP6 (EC 2.3.2.27) (Proliferation potential-related protein) (Protein P2P-R) (RING-type E3 ubiquitin transferase RBBP6) (Retinoblastoma-binding Q protein 1) (RBQ-1) (Retinoblastoma-binding protein 6) (p53-associated cellular protein of testis)	5	UniProt NCBI
SRSF10	Serine/arginine-rich splicing factor 10 (40 kDa SR-repressor protein) (SRrp40) (FUS-interacting serine-arginine-rich protein 1) (Splicing factor SRp38) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)	5	UniProt NCBI
SRSF9	Serine/arginine-rich splicing factor 9 (Pre-mRNA-splicing factor SRp30C) (Splicing factor, arginine/serine-rich 9)	5	UniProt NCBI
SNIP1	Smad nuclear-interacting protein 1 (FHA domain-containing protein SNIP1)	5	UniProt NCBI
SRRT	Serrate RNA effector molecule homolog (Arsenite-resistance protein 2)	5	UniProt NCBI
FIP1L1	Pre-mRNA 3'-end-processing factor FIP1 (hFip1) (FIP1-like 1 protein) (Factor interacting with PAP) (Rearranged in hypereosinophilia)	5	UniProt NCBI
TRA2B	Transformer-2 protein homolog beta (TRA-2 beta) (TRA2-beta) (hTRA2-beta) (Splicing factor, arginine/serine-rich 10) (Transformer-2 protein homolog B)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0008380	1.70281492364e-15	0.714285714286	CLK1 CLK2 SRSF12 CLK3 TRA2B SRSF8 SRSF7 SRSF9 SRSF10 TRA2A PPIG YTHDC1 SNIP1 NCBP1 LUC7L2	RNA splicing
GO:0003723	3.43912431458e-13	0.904761904762	APOBEC3F SRRT PPIG FIP1L1 SRSF12 CLK3 TRA2B SRSF7 RBBP6 SRSF8 MKRN1 SRSF9 SRSF10 TRA2A SPEN YTHDC1 SNIP1 NCBP1 LUC7L2	RNA binding
GO:0006396	2.26400023984e-12	0.761904761905	CLK1 SRRT CLK2 SRSF12 CLK3 TRA2B SRSF8 SRSF7 SRSF9 SRSF10 TRA2A PPIG YTHDC1 SNIP1 NCBP1 LUC7L2	RNA processing
GO:0043484	2.30798911671e-12	0.52380952381	CLK1 CLK2 CLK3 TRA2B SRSF7 SRSF12 SRSF9 TRA2A YTHDC1 NCBP1 SRSF10	regulation of RNA splicing
REAC:R-HSA-72203	7.88477789119e-12	0.52380952381	SRRT PPIG FIP1L1 SRSF9 TRA2B SRSF7 SRSF12 SRSF8 SRSF10 NCBP1 SNIP1	Processing of Capped Intron-Containing Pre-mRNA
REAC:R-HSA-72163	1.91715057031e-11	0.47619047619	SRRT PPIG SRSF9 TRA2B SRSF7 SRSF12 SRSF8 SRSF10 NCBP1 SNIP1	mRNA Splicing - Major Pathway
REAC:R-HSA-72172	2.70770091674e-11	0.47619047619	SRRT PPIG SRSF9 TRA2B SRSF7 SRSF12 SRSF8 SRSF10 NCBP1 SNIP1	mRNA Splicing
WP:WP411	4.26736930936e-10	0.380952380952	CLK1 CLK2 CLK3 SRSF7 TRA2B SRSF9 SRSF10 NCBP1	mRNA processing
GO:0000398	8.8690910676e-10	0.52380952381	SRSF8 TRA2B SRSF7 SRSF12 SRSF9 SRSF10 TRA2A YTHDC1 SNIP1 NCBP1 LUC7L2	mRNA splicing, via spliceosome
GO:0000377	8.8690910676e-10	0.52380952381	SRSF8 TRA2B SRSF7 SRSF12 SRSF9 SRSF10 TRA2A YTHDC1 SNIP1 NCBP1 LUC7L2	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
GO:0000375	1.04578217652e-09	0.52380952381	SRSF8 TRA2B SRSF7 SRSF12 SRSF9 SRSF10 TRA2A YTHDC1 SNIP1 NCBP1 LUC7L2	RNA splicing, via transesterification reactions
GO:0048024	8.10477599202e-09	0.380952380952	TRA2B SRSF7 NCBP1 SRSF9 SRSF10 YTHDC1 SRSF12 TRA2A	regulation of mRNA splicing, via spliceosome
GO:0006397	1.12067112315e-08	0.52380952381	SRSF8 TRA2B SRSF7 SRSF12 SRSF9 SRSF10 TRA2A YTHDC1 SNIP1 NCBP1 LUC7L2	mRNA processing
KEGG:03040	1.74813822696e-08	0.333333333333	TRA2B SRSF7 SRSF8 SRSF9 SRSF10 NCBP1 TRA2A	Spliceosome
GO:0050684	5.09770895114e-08	0.380952380952	TRA2B SRSF7 NCBP1 SRSF9 SRSF10 YTHDC1 SRSF12 TRA2A	regulation of mRNA processing
GO:0003676	1.18785792213e-07	0.904761904762	APOBEC3F SRRT PPIG FIP1L1 SRSF12 CLK3 TRA2B SRSF7 RBBP6 SRSF8 MKRN1 SRSF9 SRSF10 TRA2A SPEN YTHDC1 SNIP1 NCBP1 LUC7L2	nucleic acid binding
REAC:R-HSA-8953854	1.60473495857e-07	0.52380952381	SRRT PPIG FIP1L1 SRSF9 TRA2B SRSF7 SRSF12 SRSF8 SRSF10 NCBP1 SNIP1	Metabolism of RNA
GO:0000245	2.11006543132e-07	0.333333333333	SNIP1 SRSF12 SRSF9 LUC7L2 YTHDC1 NCBP1 SRSF10	spliceosomal complex assembly
CORUM:351	1.02016037472e-06	0.285714285714	SRRT SPEN SRSF7 NCBP1 SRSF9 TRA2B	Spliceosome
HPA:0570812	1.51652974167e-06	0.714285714286	CLK1 CLK2 FIP1L1 SRRT CLK3 TRA2B SRSF8 SRSF7 SRSF9 LUC7L2 SPEN YTHDC1 SNIP1 NCBP1 PPIG	testis; spermatogonia cells[>=Medium]
GO:0016071	2.630182658e-06	0.52380952381	SRSF8 TRA2B SRSF7 SRSF12 SRSF9 SRSF10 TRA2A YTHDC1 SNIP1 NCBP1 LUC7L2	mRNA metabolic process
HPA:0570782	3.82669549568e-06	0.571428571429	CLK2 FIP1L1 CLK3 TRA2B SRSF8 SRSF7 SRRT LUC7L2 SPEN YTHDC1 NCBP1 PPIG	testis; preleptotene spermatocytes[>=Medium]
GO:0016607	5.85299954783e-06	0.428571428571	PPIG RBBP6 SRSF7 SRSF8 SRSF9 LUC7L2 YTHDC1 SRSF12 SRSF10	nuclear speck
GO:0097159	6.14468947785e-06	0.904761904762	APOBEC3F SRRT PPIG FIP1L1 SRSF12 CLK3 TRA2B SRSF7 RBBP6 SRSF8 MKRN1 SRSF9 SRSF10 TRA2A SPEN YTHDC1 SNIP1 NCBP1 LUC7L2	organic cyclic compound binding
GO:0006376	1.44979241307e-05	0.238095238095	YTHDC1 SRSF9 SRSF10 SRSF12 LUC7L2	mRNA splice site recognition
GO:0016604	1.57843729989e-05	0.52380952381	CLK2 SRRT RBBP6 SRSF8 SRSF7 SRSF9 SRSF10 LUC7L2 YTHDC1 SRSF12 PPIG	nuclear body
HPA:0570811	1.60931307811e-05	0.714285714286	CLK1 CLK2 FIP1L1 SRRT CLK3 TRA2B SRSF8 SRSF7 SRSF9 LUC7L2 SPEN YTHDC1 SNIP1 NCBP1 PPIG	testis; spermatogonia cells[>=Low]
GO:0090304	2.18533838634e-05	0.904761904762	CLK1 SRRT CLK2 SRSF12 CLK3 TRA2B SRSF8 RBBP6 SRSF7 SRSF9 APOBEC3F PPIG SRSF10 TRA2A SPEN YTHDC1 SNIP1 NCBP1 LUC7L2	nucleic acid metabolic process
HPA:0570791	3.56708316093e-05	0.619047619048	PPIG FIP1L1 SRSF12 CLK3 TRA2B SRSF7 SRSF8 SRRT LUC7L2 SPEN YTHDC1 NCBP1 SNIP1	testis; round or early spermatids[>=Low]
GO:1903311	3.85342708351e-05	0.380952380952	TRA2B SRSF7 NCBP1 SRSF9 SRSF10 YTHDC1 SRSF12 TRA2A	regulation of mRNA metabolic process
HPA:0570792	3.96054105732e-05	0.571428571429	PPIG FIP1L1 CLK3 TRA2B SRSF7 SRSF8 SRRT LUC7L2 SPEN YTHDC1 NCBP1 SNIP1	testis; round or early spermatids[>=Medium]
HPA:0570813	5.09755795655e-05	0.52380952381	PPIG SRRT CLK3 TRA2B SRSF8 FIP1L1 SRSF9 SPEN YTHDC1 NCBP1 SNIP1	testis; spermatogonia cells[High]
GO:0016070	5.167268425e-05	0.857142857143	CLK1 SRRT CLK2 SRSF12 CLK3 TRA2B SRSF8 SRSF7 SRSF9 APOBEC3F PPIG SRSF10 TRA2A SPEN YTHDC1 SNIP1 NCBP1 LUC7L2	RNA metabolic process
HPA:0570781	5.54452134099e-05	0.571428571429	CLK2 FIP1L1 CLK3 TRA2B SRSF8 SRSF7 SRRT LUC7L2 SPEN YTHDC1 NCBP1 PPIG	testis; preleptotene spermatocytes[>=Low]
GO:0006139	0.000151250327636	0.904761904762	CLK1 SRRT CLK2 SRSF12 CLK3 TRA2B SRSF8 RBBP6 SRSF7 SRSF9 APOBEC3F PPIG SRSF10 TRA2A SPEN YTHDC1 SNIP1 NCBP1 LUC7L2	nucleobase-containing compound metabolic process
HPA:0570793	0.000161085597498	0.428571428571	SNIP1 FIP1L1 SPEN TRA2B SRSF7 SRSF8 SRRT NCBP1 PPIG	testis; round or early spermatids[High]
CORUM:6072	0.000204660259961	0.0952380952381	SRSF9 TRA2B	TRA2B1-SRSF9-SRSF6 complex
GO:0022618	0.000241540248354	0.333333333333	SNIP1 SRSF12 SRSF9 LUC7L2 YTHDC1 NCBP1 SRSF10	protein-RNA complex assembly
HPA:0570771	0.00024467077555	0.380952380952	PPIG CLK3 TRA2B SRSF7 SRSF8 SPEN NCBP1 SNIP1	testis; peritubular cells[>=Low]
GO:0046483	0.000257725007958	0.904761904762	CLK1 SRRT CLK2 SRSF12 CLK3 TRA2B SRSF8 RBBP6 SRSF7 SRSF9 APOBEC3F PPIG SRSF10 TRA2A SPEN YTHDC1 SNIP1 NCBP1 LUC7L2	heterocycle metabolic process
GO:0006725	0.000272777730472	0.904761904762	CLK1 SRRT CLK2 SRSF12 CLK3 TRA2B SRSF8 RBBP6 SRSF7 SRSF9 APOBEC3F PPIG SRSF10 TRA2A SPEN YTHDC1 SNIP1 NCBP1 LUC7L2	cellular aromatic compound metabolic process
GO:0048025	0.000283430217157	0.190476190476	SRSF9 SRSF10 SRSF7 SRSF12	negative regulation of mRNA splicing, via spliceosome
REAC:R-HSA-72187	0.000328316671191	0.190476190476	SRSF9 SRSF7 FIP1L1 NCBP1	mRNA 3'-end processing
GO:0071826	0.000335466701501	0.333333333333	SNIP1 SRSF12 SRSF9 LUC7L2 YTHDC1 NCBP1 SRSF10	protein-RNA complex organization
GO:0005654	0.000352027648697	0.857142857143	SRRT CLK2 FIP1L1 SRSF12 CLK3 TRA2B SRSF8 RBBP6 SRSF7 SRSF9 PPIG SRSF10 TRA2A SPEN YTHDC1 SNIP1 NCBP1 LUC7L2	nucleoplasm
HPA:0570772	0.000440577743915	0.333333333333	SNIP1 CLK3 SRSF7 SRSF8 SPEN TRA2B PPIG	testis; peritubular cells[>=Medium]
GO:0050686	0.000475649605248	0.190476190476	SRSF9 SRSF10 SRSF7 SRSF12	negative regulation of mRNA processing
GO:1901360	0.000527029251402	0.904761904762	CLK1 SRRT CLK2 SRSF12 CLK3 TRA2B SRSF8 RBBP6 SRSF7 SRSF9 APOBEC3F PPIG SRSF10 TRA2A SPEN YTHDC1 SNIP1 NCBP1 LUC7L2	organic cyclic compound metabolic process
REAC:R-HSA-73856	0.000569156879424	0.190476190476	SRSF9 SRSF7 FIP1L1 NCBP1	RNA Polymerase II Transcription Termination
HPA:0570761	0.000639815296996	0.571428571429	PPIG FIP1L1 SRSF12 CLK3 TRA2B SRSF7 SRSF8 SRRT LUC7L2 SPEN YTHDC1 NCBP1	testis; pachytene spermatocytes[>=Low]
GO:0000380	0.000799889312806	0.238095238095	YTHDC1 SRSF9 TRA2B NCBP1 SRSF12	alternative mRNA splicing, via spliceosome
HPA:0301361	0.000822457526788	0.428571428571	PPIG SRRT SPEN TRA2B SRSF7 FIP1L1 SRSF9 YTHDC1 NCBP1	lung; alveolar cells type I[>=Low]
GO:0033119	0.000927718555523	0.190476190476	SRSF9 SRSF10 SRSF7 SRSF12	negative regulation of RNA splicing
GO:0031981	0.00105967192723	0.857142857143	SRRT CLK2 FIP1L1 SRSF12 CLK3 TRA2B SRSF8 RBBP6 SRSF7 SRSF9 PPIG SRSF10 TRA2A SPEN YTHDC1 SNIP1 NCBP1 LUC7L2	nuclear lumen
HPA:0130243	0.0011542350675	0.380952380952	PPIG SPEN TRA2B SRSF8 FIP1L1 SRRT YTHDC1 NCBP1	colon; peripheral nerve/ganglion[High]
GO:0034641	0.00117206034919	0.904761904762	CLK1 SRRT CLK2 SRSF12 CLK3 TRA2B SRSF8 RBBP6 SRSF7 SRSF9 APOBEC3F PPIG SRSF10 TRA2A SPEN YTHDC1 SNIP1 NCBP1 LUC7L2	cellular nitrogen compound metabolic process
REAC:R-HSA-72202	0.00141437999781	0.190476190476	SRSF9 SRSF7 FIP1L1 NCBP1	Transport of Mature Transcript to Cytoplasm
REAC:R-HSA-9013422	0.00142472650207	0.142857142857	SPEN RBBP6 TRA2B	RHOBTB1 GTPase cycle
HPA:0570763	0.00164098982239	0.380952380952	PPIG SPEN TRA2B SRSF8 FIP1L1 SRRT YTHDC1 NCBP1	testis; pachytene spermatocytes[High]
HPA:0620222	0.00171494333448	0.714285714286	CLK2 FIP1L1 SRRT CLK3 TRA2B SRSF8 RBBP6 SRSF7 SRSF9 LUC7L2 SPEN YTHDC1 SNIP1 NCBP1 PPIG	vagina; squamous epithelial cells[>=Medium]
GO:0005634	0.00289795525695	0.952380952381	CLK1 SRRT CLK2 FIP1L1 SRSF12 CLK3 TRA2B SRSF8 RBBP6 SRSF7 SRSF9 APOBEC3F PPIG SRSF10 TRA2A SPEN YTHDC1 SNIP1 NCBP1 LUC7L2	nucleus
HPA:0490692	0.0031296064707	0.619047619048	PPIG FIP1L1 SRRT CLK3 TRA2B SRSF7 SRSF8 SRSF9 LUC7L2 SPEN YTHDC1 NCBP1 SNIP1	smooth muscle; smooth muscle cells[>=Medium]
GO:0003729	0.00359039546288	0.333333333333	SNIP1 SPEN SRSF7 TRA2B LUC7L2 YTHDC1 NCBP1	mRNA binding
HPA:0100122	0.00428436858742	0.571428571429	CLK1 PPIG SRRT SPEN TRA2B SRSF7 SRSF8 SRSF9 LUC7L2 YTHDC1 NCBP1 SNIP1	cerebral cortex; glial cells[>=Medium]
HPA:0570762	0.00502894251321	0.47619047619	PPIG CLK3 TRA2B SRSF8 FIP1L1 SRRT LUC7L2 SPEN YTHDC1 NCBP1	testis; pachytene spermatocytes[>=Medium]
REAC:R-HSA-9706574	0.00520722478927	0.142857142857	SPEN RBBP6 TRA2B	RHOBTB GTPase Cycle
HPA:0301363	0.00668665143172	0.285714285714	PPIG SPEN SRSF7 SRRT YTHDC1 TRA2B	lung; alveolar cells type I[High]
HPA:0130242	0.00947745547443	0.619047619048	PPIG FIP1L1 CLK3 TRA2B SRSF7 RBBP6 SRSF8 SRRT LUC7L2 SPEN YTHDC1 NCBP1 SNIP1	colon; peripheral nerve/ganglion[>=Medium]
HPA:0090182	0.010671457681	0.571428571429	PPIG FIP1L1 SRRT SPEN TRA2B SRSF7 RBBP6 SRSF8 SRSF9 LUC7L2 YTHDC1 NCBP1	cerebellum; cells in granular layer[>=Medium]
HPA:0090162	0.0133099275931	0.666666666667	CLK1 CLK2 FIP1L1 SPEN TRA2B SRSF8 RBBP6 SRSF7 SRSF9 LUC7L2 YTHDC1 SNIP1 NCBP1 PPIG	cerebellum; Purkinje cells[>=Medium]
HPA:0570801	0.0136323485555	0.52380952381	PPIG SRRT CLK3 TRA2B SRSF8 FIP1L1 SRSF9 LUC7L2 SPEN NCBP1 SNIP1	testis; sertoli cells[>=Low]
HPA:0380513	0.016100355376	0.380952380952	PPIG SRRT SPEN TRA2B FIP1L1 SRSF9 YTHDC1 NCBP1	placenta; decidual cells[High]
GO:0019219	0.0161042757823	0.714285714286	CLK1 SRRT CLK2 APOBEC3F CLK3 TRA2B SRSF7 RBBP6 SRSF12 SRSF9 TRA2A SPEN YTHDC1 NCBP1 SRSF10	regulation of nucleobase-containing compound metabolic process
HPA:0380512	0.0164893301487	0.619047619048	PPIG FIP1L1 SRRT CLK3 TRA2B SRSF7 RBBP6 SRSF9 LUC7L2 SPEN YTHDC1 NCBP1 SNIP1	placenta; decidual cells[>=Medium]
HPA:0090193	0.0173223422511	0.333333333333	PPIG SPEN SRSF8 TRA2B SRSF9 YTHDC1 FIP1L1	cerebellum; cells in molecular layer[High]
HPA:0270352	0.0182915458734	0.571428571429	CLK2 CLK3 TRA2B SRSF8 FIP1L1 SRRT LUC7L2 SPEN YTHDC1 SNIP1 NCBP1 PPIG	kidney; cells in glomeruli[>=Medium]
HPA:0130201	0.0188286066982	0.761904761905	CLK1 CLK2 FIP1L1 SRRT CLK3 TRA2B SRSF8 RBBP6 SRSF7 SRSF9 LUC7L2 SPEN YTHDC1 SNIP1 NCBP1 PPIG	colon; endothelial cells[>=Low]
HPA:0130241	0.0233880605348	0.714285714286	CLK1 CLK2 FIP1L1 CLK3 TRA2B SRSF8 RBBP6 SRSF7 SRRT LUC7L2 SPEN YTHDC1 SNIP1 NCBP1 PPIG	colon; peripheral nerve/ganglion[>=Low]
HPA:0630222	0.0257100353706	0.619047619048	CLK2 FIP1L1 CLK3 TRA2B SRSF8 RBBP6 SRSF7 SRRT LUC7L2 SPEN YTHDC1 NCBP1 PPIG	cervix; squamous epithelial cells[>=Medium]
HPA:0270362	0.026021336416	0.761904761905	CLK1 CLK2 FIP1L1 SRRT CLK3 TRA2B SRSF8 RBBP6 SRSF7 SRSF9 LUC7L2 SPEN YTHDC1 SNIP1 NCBP1 PPIG	kidney; cells in tubules[>=Medium]
HPA:0190222	0.0288439111602	0.714285714286	CLK2 FIP1L1 SRRT CLK3 TRA2B SRSF8 RBBP6 SRSF7 SRSF9 LUC7L2 SPEN YTHDC1 SNIP1 NCBP1 PPIG	esophagus; squamous epithelial cells[>=Medium]
GO:0009059	0.0342648932229	0.857142857143	CLK1 SRRT CLK2 SRSF12 CLK3 TRA2B SRSF8 SRSF7 SRSF9 APOBEC3F PPIG SRSF10 TRA2A SPEN YTHDC1 SNIP1 NCBP1 LUC7L2	macromolecule biosynthetic process
GO:0022613	0.0397702063152	0.333333333333	SNIP1 SRSF12 SRSF9 LUC7L2 YTHDC1 NCBP1 SRSF10	ribonucleoprotein complex biogenesis
GO:0070013	0.0398416860827	0.857142857143	SRRT CLK2 FIP1L1 SRSF12 CLK3 TRA2B SRSF8 RBBP6 SRSF7 SRSF9 PPIG SRSF10 TRA2A SPEN YTHDC1 SNIP1 NCBP1 LUC7L2	intracellular organelle lumen
GO:0031974	0.0398416860827	0.857142857143	SRRT CLK2 FIP1L1 SRSF12 CLK3 TRA2B SRSF8 RBBP6 SRSF7 SRSF9 PPIG SRSF10 TRA2A SPEN YTHDC1 SNIP1 NCBP1 LUC7L2	membrane-enclosed lumen
GO:0043233	0.0398416860827	0.857142857143	SRRT CLK2 FIP1L1 SRSF12 CLK3 TRA2B SRSF8 RBBP6 SRSF7 SRSF9 PPIG SRSF10 TRA2A SPEN YTHDC1 SNIP1 NCBP1 LUC7L2	organelle lumen
HPA:0080121	0.0407359956348	0.666666666667	CLK1 CLK2 FIP1L1 SRRT SPEN TRA2B SRSF8 SRSF7 SRSF9 LUC7L2 YTHDC1 SNIP1 NCBP1 PPIG	caudate; glial cells[>=Low]
HPA:0570802	0.0408561551691	0.428571428571	SNIP1 CLK3 TRA2B SRSF8 FIP1L1 SRRT LUC7L2 NCBP1 PPIG	testis; sertoli cells[>=Medium]
HPA:0470683	0.0410650368578	0.333333333333	CLK3 SRSF8 FIP1L1 SRRT SPEN YTHDC1 NCBP1	skin 2; epidermal cells[High]
REAC:R-HSA-159236	0.0421654372186	0.142857142857	SRSF9 SRSF7 NCBP1	Transport of Mature mRNA derived from an Intron-Containing Transcript
HPA:0080122	0.0429053774171	0.47619047619	PPIG SRRT SPEN TRA2B SRSF7 SRSF8 SRSF9 YTHDC1 NCBP1 SNIP1	caudate; glial cells[>=Medium]
HPA:0620000	0.0459751188163	0.761904761905	CLK1 CLK2 FIP1L1 SRRT CLK3 TRA2B SRSF8 RBBP6 SRSF7 SRSF9 LUC7L2 SPEN YTHDC1 SNIP1 NCBP1 PPIG	vagina
HPA:0620221	0.0459751188163	0.761904761905	CLK1 CLK2 FIP1L1 SRRT CLK3 TRA2B SRSF8 RBBP6 SRSF7 SRSF9 LUC7L2 SPEN YTHDC1 SNIP1 NCBP1 PPIG	vagina; squamous epithelial cells[>=Low]
HPA:0100133	0.0466988902216	0.428571428571	PPIG SRRT SPEN TRA2B SRSF8 FIP1L1 SRSF9 YTHDC1 NCBP1	cerebral cortex; neuronal cells[High]
GO:0051252	0.0468361680777	0.666666666667	CLK1 SRRT CLK2 APOBEC3F CLK3 TRA2B SRSF7 SRSF12 SRSF9 TRA2A SPEN YTHDC1 NCBP1 SRSF10	regulation of RNA metabolic process

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
CLK2	CLK1	0.999	0.078
SRSF8	CLK3	0.999	0.072	structurally_consistent (O00422)
SRSF8	CLK2	0.999	0.086
TRA2A	SRSF7	0.999	0.78	mutually_exclusive (O00422)
SRSF10	CLK2	0.999
SRSF10	CLK3	0.998		structurally_consistent (O00422)
CLK3	SRSF9	0.998	0.366
TRA2B	SRSF7	0.998	0.982
TRA2A	TRA2B	0.998	0.934	mutually_exclusive (P38919)
CLK3	PPIG	0.998	0.102
SRSF10	SRSF7	0.997
TRA2A	SRSF10	0.997		mutually_exclusive (O00422)
TRA2B	CLK3	0.997	0.428
SRRT	CLK2	0.997	0.164
CLK3	YTHDC1	0.997	0.144666666667
RBBP6	YTHDC1	0.997	0.254
CLK2	YTHDC1	0.997	0.13
TRA2A	CLK3	0.997	0.298
CLK2	CLK3	0.996	0.156	structurally_consistent (dimer)
SRRT	YTHDC1	0.996	0.324
TRA2A	NCBP1	0.996	0.18
TRA2A	SRSF12	0.996	0.9
SRRT	NCBP1	0.996	0.65
LUC7L2	SRSF9	0.996	0.432
TRA2A	SRSF9	0.995	0.594
SRSF9	PPIG	0.994	0.322
TRA2B	CLK2	0.994	0.158
SRRT	RBBP6	0.994	0.398
CLK2	SRSF9	0.994	0.18
TRA2A	PPIG	0.993	0.206
TRA2A	MKRN1	0.993	0.068
APOBEC3F	CLK3	0.993	0.088
SRSF9	SRSF7	0.993	0.576	mutually_exclusive (P61326)
SRSF12	LUC7L2	0.993	0.574	structurally_consistent (dimer)
CLK1	SRSF7	0.993	0.354
TRA2A	CLK1	0.992	0.128
LUC7L2	SRSF7	0.992	0.786	structurally_consistent (dimer)
SRSF8	LUC7L2	0.992	0.232	structurally_consistent (dimer)
CLK3	SRSF7	0.991	0.344	structurally_consistent (O00422)
TRA2B	LUC7L2	0.991	0.706
NCBP1	YTHDC1	0.989	0.118
SRSF10	LUC7L2	0.988
TRA2A	CLK2	0.988	0.174	structurally_consistent (dimer)
CLK2	SRSF7	0.987	0.092	structurally_consistent (Q9Y383)
RBBP6	SRSF7	0.987	0.358
SRSF10	YTHDC1	0.987
SRSF12	CLK2	0.987	0.084
SNIP1	SRSF9	0.986	0.66	mutually_exclusive (P78362) structurally_consistent (dimer)
CLK2	RBBP6	0.985	0.164
SRRT	CLK3	0.985	0.22
SRRT	SRSF10	0.984		mutually_exclusive (P52298)
CLK3	RBBP6	0.984	0.252
TRA2A	YTHDC1	0.983	0.408
TRA2B	SNIP1	0.982	0.782
RBBP6	CLK1	0.981	0.138
SRSF7	PPIG	0.981	0.412	mutually_exclusive (P61326)
TRA2A	SRSF8	0.979	0.518	mutually_exclusive (O00422)
SRSF10	MKRN1	0.978
CLK2	LUC7L2	0.977	0.12	structurally_consistent (dimer)
SRRT	TRA2B	0.976	0.87
SPEN	PPIG	0.976	0.132
SRSF8	PPIG	0.975	0.164	mutually_exclusive (P61326)
SRSF10	TRA2B	0.975		mutually_exclusive (P61326)
SRSF8	CLK1	0.974	0.076
NCBP1	SRSF7	0.974	0.368
TRA2B	SRSF9	0.972	0.594	structurally_consistent (P61326)
SRRT	SNIP1	0.971	0.434
TRA2B	MKRN1	0.97	0.142
TRA2A	SRRT	0.969	0.606
FIP1L1	CLK2	0.969	0.164
FIP1L1	CLK1	0.968	0.144
FIP1L1	TRA2A	0.967	0.454
TRA2A	RBBP6	0.967	0.122
CLK3	CLK1	0.967	0.19
SPEN	CLK3	0.965	0.096
MKRN1	CLK3	0.964	0.122
SNIP1	SRSF7	0.964	0.762	mutually_exclusive (Q9Y383)
TRA2A	SNIP1	0.962	0.652
CLK1	PPIG	0.959	0.198
SRSF8	SRSF7	0.959	0.33775
SRSF12	CLK3	0.958	0.21	structurally_consistent (dimer)
FIP1L1	CLK3	0.957	0.395
APOBEC3F	SRSF7	0.957	0.148
SRSF8	RBBP6	0.957	0.288
SRSF8	SNIP1	0.955	0.16
SRSF10	SRSF9	0.955		structurally_consistent (dimer)
SPEN	SRSF9	0.954	0.11
NCBP1	CLK2	0.954	0.102
SNIP1	PPIG	0.954	0.348
NCBP1	MKRN1	0.951	0.13
RBBP6	SRSF9	0.948	0.304
TRA2B	NCBP1	0.946	0.612
CLK1	YTHDC1	0.946	0.134
YTHDC1	PPIG	0.945	0.196
CLK3	LUC7L2	0.944	0.2
SRRT	CLK1	0.943	0.234
NCBP1	PPIG	0.942	0.536
CLK1	SRSF9	0.942	0.346
APOBEC3F	CLK1	0.942	0.086
SRSF10	PPIG	0.941		mutually_exclusive (P61326)
NCBP1	RBBP6	0.938	0.414
SRSF10	NCBP1	0.935
SRSF10	CLK1	0.935
TRA2B	CLK1	0.935	0.374
SRRT	LUC7L2	0.935	0.828	mutually_exclusive (P52298)
SRSF8	YTHDC1	0.934	0.17
TRA2B	PPIG	0.934	0.532
RBBP6	PPIG	0.932	0.218
APOBEC3F	SRSF8	0.932	0.082
SRSF10	SNIP1	0.93		mutually_exclusive (Q13242)
MKRN1	SRSF12	0.93	0.078
MKRN1	LUC7L2	0.929	0.126
MKRN1	SRSF7	0.927	0.158
APOBEC3F	YTHDC1	0.926	0.056
TRA2B	RBBP6	0.926	0.258
YTHDC1	SRSF7	0.923	0.494
MKRN1	SRSF8	0.92	0.112
SRRT	PPIG	0.919	0.524
SRRT	SRSF8	0.917	0.236
SRSF12	SRSF9	0.915	0.768	structurally_consistent (P61326)
CLK2	PPIG	0.914	0.112
MKRN1	SRSF9	0.914	0.152
FIP1L1	TRA2B	0.911	0.59	mutually_exclusive (P61326)
SRSF10	APOBEC3F	0.909
TRA2B	APOBEC3F	0.907	0.27
SRSF12	YTHDC1	0.906	0.734
SRRT	SRSF7	0.904	0.772
SRSF10	SRSF12	0.899
SRSF10	RBBP6	0.899
CLK2	SNIP1	0.897	0.186	structurally_consistent (dimer)
SRSF8	SRSF12	0.895	0.212	mutually_exclusive (P61326)
APOBEC3F	RBBP6	0.891	0.042
FIP1L1	LUC7L2	0.891	0.508
SRSF8	SRSF9	0.885	0.556	structurally_consistent (P61326)
SNIP1	YTHDC1	0.883	0.484
APOBEC3F	MKRN1	0.882	0.108
NCBP1	CLK3	0.881	0.372
SRRT	SRSF9	0.879	0.588	mutually_exclusive (P52298)
TRA2A	APOBEC3F	0.876	0.132
NCBP1	SNIP1	0.875	0.688
NCBP1	SRSF8	0.875	0.7008
APOBEC3F	CLK2	0.873	0.086
FIP1L1	SRSF8	0.86	0.483333333333	mutually_exclusive (P61326)
FIP1L1	SNIP1	0.852	0.576
FIP1L1	PPIG	0.841	0.546	mutually_exclusive (P61326)
LUC7L2	SNIP1	0.839	0.496	structurally_consistent (dimer)
SRSF12	RBBP6	0.832	0.16
APOBEC3F	PPIG	0.832	0.052
TRA2B	SRSF12	0.829	0.874
NCBP1	SRSF9	0.811	0.322	mutually_exclusive (P52298)
FIP1L1	SRSF7	0.806	0.66	mutually_exclusive (P61326)
TRA2B	YTHDC1	0.8	0.544	mutually_exclusive (P38919)
MKRN1	SNIP1	0.785	0.13
MKRN1	CLK2	0.782	0.112
SRSF10	SRSF8	0.779
SRRT	SRSF12	0.769	0.472
FIP1L1	RBBP6	0.769	0.16
NCBP1	LUC7L2	0.767	0.374
APOBEC3F	SRSF9	0.744	0.16
TRA2B	SRSF8	0.739	0.562	mutually_exclusive (P61326)
SRSF12	SRSF7	0.729	0.816
SRSF12	PPIG	0.723	0.308	mutually_exclusive (P61326)
FIP1L1	SRSF10	0.71		mutually_exclusive (P61326)
NCBP1	CLK1	0.707	0.41
SRSF9	YTHDC1	0.706	0.22
TRA2A	LUC7L2	0.706	0.268
SRSF12	CLK1	0.696	0.078
MKRN1	YTHDC1	0.693	0.084
NCBP1	SRSF12	0.692	0.17
FIP1L1	SRSF12	0.663	0.684	mutually_exclusive (P61326)
FIP1L1	SRSF9	0.651	0.734	mutually_exclusive (P61326)
RBBP6	LUC7L2	0.634	0.26
FIP1L1	MKRN1	0.633	0.03
SRRT	APOBEC3F	0.604	0.124
FIP1L1	SRRT	0.58	0.768
MKRN1	PPIG	0.579	0.036
SPEN	SRSF8	0.575	0.136
APOBEC3F	SPEN	0.563	0.068
APOBEC3F	SRSF12	0.548	0.108
SRSF12	SNIP1	0.545	0.394
LUC7L2	PPIG	0.538	0.276
SRRT	MKRN1	0.468	0.134
NCBP1	APOBEC3F	0.409	0.122
RBBP6	SNIP1	0.385	0.394
FIP1L1	YTHDC1	0.367	0.428
FIP1L1	NCBP1	0.331	0.4
MKRN1	RBBP6	0.317	0.06
FIP1L1	APOBEC3F	0.258	0.11
CLK1	LUC7L2	0.258	0.192
MKRN1	CLK1	0.208	0.092
APOBEC3F	LUC7L2	0.207	0.09
SPEN	SRSF12	0.2	0.134
LUC7L2	YTHDC1	0.19	0.212
SPEN	YTHDC1	0.183	0.238
SPEN	SNIP1	0.14	0.26
SPEN	CLK1	0.098	0.086
SPEN	CLK2	0.07	0.076
TRA2A	SPEN	0.065	0.126
TRA2B	SPEN	0.053	0.274615384615
SRRT	SPEN	0.05	0.082
SPEN	SRSF7	0.036	0.138
CLK3	SNIP1	0.028	0.258
NCBP1	SPEN	0.022	0.198
SRSF10	SPEN	0.019
FIP1L1	SPEN	0.018	0.284
MKRN1	SPEN	0.015	0.16
SPEN	LUC7L2	0.014	0.076
SPEN	RBBP6	0.007	0.094

Related Complexes

Genename	Complexes
SRSF7	huMAP3_06081.1 huMAP3_06097.1 huMAP3_06391.1 huMAP3_07267.1 huMAP3_08467.1 huMAP3_08486.1 huMAP3_09587.1 huMAP3_09621.1 huMAP3_09943.1 huMAP3_10564.1 huMAP3_11073.1
CLK2	huMAP3_02684.1 huMAP3_03369.1 huMAP3_03519.1 huMAP3_05378.1 huMAP3_06097.1 huMAP3_06219.1 huMAP3_06975.1 huMAP3_07411.1 huMAP3_07724.1 huMAP3_08614.1 huMAP3_08829.1 huMAP3_09490.1 huMAP3_09587.1 huMAP3_09621.1 huMAP3_09943.1 huMAP3_10564.1 huMAP3_10628.1 huMAP3_11073.1
MKRN1	huMAP3_00714.1 huMAP3_03962.1 huMAP3_05745.1 huMAP3_05874.1 huMAP3_06081.1 huMAP3_06391.1 huMAP3_06975.1 huMAP3_07267.1 huMAP3_07661.1 huMAP3_07973.1 huMAP3_08087.1 huMAP3_08105.1 huMAP3_08467.1 huMAP3_08486.1 huMAP3_09186.1 huMAP3_09532.1 huMAP3_09587.1 huMAP3_09621.1 huMAP3_10114.1 huMAP3_10564.1 huMAP3_11047.1 huMAP3_11073.1
SRSF8	huMAP3_02311.1 huMAP3_06081.1 huMAP3_06846.1 huMAP3_07910.1 huMAP3_08087.1 huMAP3_08486.1 huMAP3_09279.1 huMAP3_09587.1 huMAP3_09621.1 huMAP3_09636.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10564.1 huMAP3_11073.1
NCBP1	huMAP3_00714.1 huMAP3_03195.1 huMAP3_03962.1 huMAP3_05745.1 huMAP3_05874.1 huMAP3_06081.1 huMAP3_06391.1 huMAP3_06975.1 huMAP3_07267.1 huMAP3_07661.1 huMAP3_07724.1 huMAP3_07910.1 huMAP3_07973.1 huMAP3_08614.1 huMAP3_09490.1 huMAP3_09587.1 huMAP3_09621.1 huMAP3_10114.1 huMAP3_10564.1 huMAP3_11047.1 huMAP3_11073.1
CLK3	huMAP3_02831.1 huMAP3_06097.1 huMAP3_06523.1 huMAP3_07291.1 huMAP3_08087.1 huMAP3_08486.1 huMAP3_08824.1 huMAP3_09587.1 huMAP3_09621.1 huMAP3_09943.1 huMAP3_10564.1 huMAP3_11073.1
SPEN	huMAP3_02019.1 huMAP3_03970.1 huMAP3_05696.1 huMAP3_05995.1 huMAP3_07848.1 huMAP3_08302.1 huMAP3_08486.1 huMAP3_08820.1 huMAP3_09041.1 huMAP3_09156.1 huMAP3_09532.1 huMAP3_09587.1 huMAP3_09943.1 huMAP3_10021.1 huMAP3_10524.1
TRA2A	huMAP3_00197.1 huMAP3_02367.1 huMAP3_03452.1 huMAP3_04705.1 huMAP3_05807.1 huMAP3_06081.1 huMAP3_06391.1 huMAP3_06589.1 huMAP3_07267.1 huMAP3_07910.1 huMAP3_09587.1 huMAP3_09621.1 huMAP3_10564.1 huMAP3_11073.1
CLK1	huMAP3_03369.1 huMAP3_04705.1 huMAP3_05341.1 huMAP3_06081.1 huMAP3_06846.1 huMAP3_07724.1 huMAP3_08467.1 huMAP3_08486.1 huMAP3_09279.1 huMAP3_09490.1 huMAP3_09587.1 huMAP3_09621.1 huMAP3_09943.1 huMAP3_11073.1
YTHDC1	huMAP3_05378.1 huMAP3_06081.1 huMAP3_06523.1 huMAP3_06975.1 huMAP3_07291.1 huMAP3_07724.1 huMAP3_08486.1 huMAP3_08824.1 huMAP3_09490.1 huMAP3_09587.1 huMAP3_09621.1 huMAP3_10564.1 huMAP3_11073.1
SRSF12	huMAP3_02684.1 huMAP3_03519.1 huMAP3_05378.1 huMAP3_06070.1 huMAP3_07724.1 huMAP3_08614.1 huMAP3_08829.1 huMAP3_09490.1 huMAP3_09587.1 huMAP3_09621.1 huMAP3_10564.1 huMAP3_10628.1 huMAP3_11073.1
APOBEC3F	huMAP3_00714.1 huMAP3_06975.1 huMAP3_07291.1 huMAP3_07939.1 huMAP3_08105.1 huMAP3_08486.1 huMAP3_09113.1 huMAP3_09186.1 huMAP3_09587.1 huMAP3_10114.1 huMAP3_10625.1
LUC7L2	huMAP3_03519.1 huMAP3_03529.1 huMAP3_06219.1 huMAP3_07724.1 huMAP3_07910.1 huMAP3_08614.1 huMAP3_09490.1 huMAP3_09587.1 huMAP3_09621.1 huMAP3_09943.1 huMAP3_10250.1 huMAP3_10564.1 huMAP3_11073.1 huMAP3_14804.1
PPIG	huMAP3_06097.1 huMAP3_06219.1 huMAP3_08467.1 huMAP3_09226.1 huMAP3_09587.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09638.1 huMAP3_09943.1 huMAP3_10564.1 huMAP3_10789.1 huMAP3_11073.1
RBBP6	huMAP3_03369.1 huMAP3_05341.1 huMAP3_06081.1 huMAP3_06391.1 huMAP3_07155.1 huMAP3_08044.1 huMAP3_08467.1 huMAP3_09279.1 huMAP3_09490.1 huMAP3_09587.1 huMAP3_09621.1 huMAP3_09636.1 huMAP3_09943.1 huMAP3_10564.1 huMAP3_11073.1
SRSF10	huMAP3_00489.1 huMAP3_04780.1 huMAP3_06081.1 huMAP3_06097.1 huMAP3_06391.1 huMAP3_07267.1 huMAP3_07848.1 huMAP3_08467.1 huMAP3_08486.1 huMAP3_09532.1 huMAP3_09587.1 huMAP3_09621.1 huMAP3_09943.1 huMAP3_10564.1 huMAP3_11073.1
SRSF9	huMAP3_03970.1 huMAP3_06007.1 huMAP3_06082.1 huMAP3_06097.1 huMAP3_06391.1 huMAP3_07267.1 huMAP3_07835.1 huMAP3_07848.1 huMAP3_09532.1 huMAP3_09587.1 huMAP3_09621.1 huMAP3_09943.1 huMAP3_10564.1 huMAP3_11073.1
SNIP1	huMAP3_03772.1 huMAP3_06391.1 huMAP3_06799.1 huMAP3_07248.1 huMAP3_07561.1 huMAP3_08365.1 huMAP3_08467.1 huMAP3_08486.1 huMAP3_09587.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10139.1 huMAP3_10564.1 huMAP3_11073.1
SRRT	huMAP3_00299.1 huMAP3_05378.1 huMAP3_06081.1 huMAP3_06391.1 huMAP3_07267.1 huMAP3_08044.1 huMAP3_08566.1 huMAP3_09490.1 huMAP3_09587.1 huMAP3_09621.1 huMAP3_09943.1 huMAP3_10564.1 huMAP3_11073.1
FIP1L1	huMAP3_00102.1 huMAP3_08087.1 huMAP3_08486.1 huMAP3_09096.1 huMAP3_09490.1 huMAP3_09587.1 huMAP3_11073.1 huMAP3_11757.1
TRA2B	huMAP3_00489.1 huMAP3_03452.1 huMAP3_04780.1 huMAP3_05748.1 huMAP3_06097.1 huMAP3_06391.1 huMAP3_06975.1 huMAP3_07267.1 huMAP3_07659.1 huMAP3_08467.1 huMAP3_09587.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10564.1 huMAP3_11073.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_09587.1

Complex Portal: CPX-25404