hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_09594.1

Complex Portal: CPX-13000

Confidence: Moderate High

Genename	Protein Name	Uniprot Annotation Score	Links
RBM10	RNA-binding protein 10 (G patch domain-containing protein 9) (RNA-binding motif protein 10) (RNA-binding protein S1-1) (S1-1)	5	UniProt NCBI
U2SURP	U2 snRNP-associated SURP motif-containing protein (140 kDa Ser/Arg-rich domain protein) (U2-associated protein SR140)	5	UniProt NCBI
RBM17	Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17)	5	UniProt NCBI
SCAF8	SR-related and CTD-associated factor 8 (CDC5L complex-associated protein 7) (RNA-binding motif protein 16)	5	UniProt NCBI
AGGF1	Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (hVG5Q) (G patch domain-containing protein 7) (Vasculogenesis gene on 5q protein)	5	UniProt NCBI
HTATSF1	17S U2 SnRNP complex component HTATSF1 (HIV Tat-specific factor 1) (Tat-SF1)	5	UniProt NCBI
CHERP	Calcium homeostasis endoplasmic reticulum protein (ERPROT 213-21) (SR-related CTD-associated factor 6)	5	UniProt NCBI
DNAJC8	DnaJ homolog subfamily C member 8 (Splicing protein spf31)	5	UniProt NCBI
CCDC124	Coiled-coil domain-containing protein 124	5	UniProt NCBI
PCNP	PEST proteolytic signal-containing nuclear protein (PCNP) (PEST-containing nuclear protein)	5	UniProt NCBI
TRIR	Telomerase RNA component interacting RNase (EC 3.1.13.-) (Exoribonuclease TRIR)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:2755	3.12883173642e-07	0.363636363636	RBM17 DNAJC8 U2SURP CHERP	17S U2 snRNP
REAC:R-HSA-72163	7.09898212624e-07	0.545454545455	DNAJC8 CHERP HTATSF1 RBM10 RBM17 U2SURP	mRNA Splicing - Major Pathway
REAC:R-HSA-72172	8.72185531784e-07	0.545454545455	DNAJC8 CHERP HTATSF1 RBM10 RBM17 U2SURP	mRNA Splicing
CORUM:351	1.97235159507e-06	0.454545454545	RBM17 DNAJC8 U2SURP TRIR HTATSF1	Spliceosome
REAC:R-HSA-72203	4.5486040572e-06	0.545454545455	DNAJC8 CHERP HTATSF1 RBM10 RBM17 U2SURP	Processing of Capped Intron-Containing Pre-mRNA
HPA:0630053	1.63812469252e-05	0.727272727273	CCDC124 U2SURP RBM17 RBM10 TRIR HTATSF1 SCAF8 PCNP	cervix; glandular cells[High]
HPA:0170252	1.74891925904e-05	0.818181818182	DNAJC8 U2SURP RBM17 RBM10 TRIR HTATSF1 SCAF8 PCNP CCDC124	endometrium 2; cells in endometrial stroma[>=Medium]
HPA:0340462	5.48377034371e-05	0.818181818182	DNAJC8 U2SURP RBM17 RBM10 TRIR HTATSF1 SCAF8 PCNP CCDC124	ovary; ovarian stroma cells[>=Medium]
HPA:0420053	9.71785777601e-05	0.727272727273	CCDC124 U2SURP RBM17 RBM10 TRIR HTATSF1 SCAF8 PCNP	salivary gland; glandular cells[High]
HPA:0130053	0.0002324629273	0.818181818182	DNAJC8 U2SURP RBM17 RBM10 TRIR HTATSF1 SCAF8 PCNP CCDC124	colon; glandular cells[High]
HPA:0620223	0.000322965791858	0.636363636364	U2SURP RBM17 RBM10 TRIR HTATSF1 SCAF8 PCNP	vagina; squamous epithelial cells[High]
HPA:0330223	0.000384179259738	0.636363636364	CCDC124 U2SURP RBM17 RBM10 HTATSF1 SCAF8 PCNP	oral mucosa; squamous epithelial cells[High]
HPA:0060103	0.000492107456039	0.727272727273	DNAJC8 U2SURP RBM17 RBM10 HTATSF1 SCAF8 PCNP CCDC124	bronchus; respiratory epithelial cells[High]
REAC:R-HSA-8953854	0.00100576045966	0.545454545455	DNAJC8 CHERP HTATSF1 RBM10 RBM17 U2SURP	Metabolism of RNA
HPA:0440343	0.00118084188761	0.545454545455	HTATSF1 RBM10 TRIR RBM17 PCNP SCAF8	skeletal muscle; myocytes[High]
HPA:0301363	0.00192145801722	0.454545454545	RBM17 HTATSF1 PCNP U2SURP SCAF8	lung; alveolar cells type I[High]
HPA:0600223	0.00196395321914	0.636363636364	CCDC124 U2SURP RBM17 RBM10 HTATSF1 SCAF8 PCNP	tonsil; squamous epithelial cells[High]
HPA:0430053	0.00198332057901	0.636363636364	CCDC124 U2SURP RBM17 RBM10 HTATSF1 SCAF8 PCNP	seminal vesicle; glandular cells[High]
HPA:0460673	0.00299787668419	0.545454545455	U2SURP RBM17 RBM10 HTATSF1 SCAF8 PCNP	skin 1; melanocytes[High]
HPA:0630223	0.00387426937682	0.545454545455	U2SURP RBM10 TRIR RBM17 SCAF8 PCNP	cervix; squamous epithelial cells[High]
HPA:0190223	0.00404552492053	0.636363636364	U2SURP RBM17 RBM10 TRIR HTATSF1 SCAF8 PCNP	esophagus; squamous epithelial cells[High]
HPA:0210053	0.00424413105961	0.636363636364	CCDC124 U2SURP RBM17 RBM10 HTATSF1 SCAF8 PCNP	fallopian tube; glandular cells[High]
KEGG:03040	0.00488559896554	0.272727272727	RBM17 U2SURP CHERP	Spliceosome
HPA:0381203	0.00489158700409	0.363636363636	HTATSF1 PCNP U2SURP SCAF8	placenta; hofbauer cells[High]
HPA:0170251	0.00548295118537	0.818181818182	DNAJC8 U2SURP RBM17 RBM10 TRIR HTATSF1 SCAF8 PCNP CCDC124	endometrium 2; cells in endometrial stroma[>=Low]
HPA:0301373	0.00739420983813	0.454545454545	RBM17 HTATSF1 PCNP U2SURP SCAF8	lung; alveolar cells type II[High]
HPA:0180053	0.00781899712104	0.636363636364	CCDC124 U2SURP HTATSF1 TRIR RBM17 PCNP SCAF8	epididymis; glandular cells[High]
HPA:0460672	0.00809613544262	0.818181818182	DNAJC8 U2SURP RBM17 RBM10 TRIR HTATSF1 SCAF8 PCNP CCDC124	skin 1; melanocytes[>=Medium]
HPA:0440342	0.00854037202389	0.818181818182	DNAJC8 U2SURP RBM17 RBM10 TRIR HTATSF1 SCAF8 PCNP CCDC124	skeletal muscle; myocytes[>=Medium]
HPA:0500652	0.00897265842972	0.727272727273	DNAJC8 U2SURP RBM17 RBM10 HTATSF1 SCAF8 PCNP CCDC124	soft tissue 1; fibroblasts[>=Medium]
HPA:0381213	0.00936270264464	0.363636363636	HTATSF1 PCNP U2SURP SCAF8	placenta; syncytiotrophoblasts - cell body[High]
HPA:0291162	0.0111915584055	0.636363636364	DNAJC8 U2SURP RBM17 RBM10 HTATSF1 SCAF8 CCDC124	liver; cholangiocytes[>=Medium]
HPA:0350473	0.0113165101183	0.636363636364	CCDC124 U2SURP RBM17 RBM10 HTATSF1 SCAF8 PCNP	pancreas; exocrine glandular cells[High]
HPA:0381202	0.0138632152238	0.363636363636	HTATSF1 PCNP U2SURP SCAF8	placenta; hofbauer cells[>=Medium]
HPA:0310442	0.0143969223789	0.818181818182	DNAJC8 U2SURP RBM17 RBM10 TRIR HTATSF1 SCAF8 PCNP CCDC124	lymph node; non-germinal center cells[>=Medium]
HPA:0500702	0.0153321588926	0.545454545455	CCDC124 U2SURP DNAJC8 RBM17 PCNP SCAF8	soft tissue 1; peripheral nerve[>=Medium]
HPA:0170053	0.0156885902686	0.545454545455	CCDC124 U2SURP HTATSF1 RBM17 PCNP SCAF8	endometrium 2; glandular cells[High]
HPA:0340461	0.0161949270037	0.818181818182	DNAJC8 U2SURP RBM17 RBM10 TRIR HTATSF1 SCAF8 PCNP CCDC124	ovary; ovarian stroma cells[>=Low]
HPA:0630052	0.0165000435065	0.818181818182	DNAJC8 U2SURP RBM17 RBM10 TRIR HTATSF1 SCAF8 PCNP CCDC124	cervix; glandular cells[>=Medium]
HPA:0620222	0.017853356606	0.818181818182	DNAJC8 U2SURP RBM17 RBM10 TRIR HTATSF1 SCAF8 PCNP CCDC124	vagina; squamous epithelial cells[>=Medium]
HPA:0050053	0.0178904755269	0.545454545455	CCDC124 U2SURP RBM17 RBM10 HTATSF1 SCAF8	breast; glandular cells[High]
HPA:0160251	0.0192143383207	0.818181818182	DNAJC8 U2SURP RBM17 RBM10 TRIR HTATSF1 SCAF8 PCNP CCDC124	endometrium 1; cells in endometrial stroma[>=Low]
HPA:0130243	0.0211621947617	0.454545454545	RBM17 DNAJC8 PCNP RBM10 HTATSF1	colon; peripheral nerve/ganglion[High]
HPA:0050093	0.0211621947617	0.454545454545	HTATSF1 RBM17 SCAF8 RBM10 U2SURP	breast; myoepithelial cells[High]
HPA:0600442	0.0213768240398	0.818181818182	DNAJC8 U2SURP RBM17 RBM10 TRIR HTATSF1 SCAF8 PCNP CCDC124	tonsil; non-germinal center cells[>=Medium]
HPA:0381201	0.0220278089947	0.363636363636	HTATSF1 PCNP U2SURP SCAF8	placenta; hofbauer cells[>=Low]
HPA:0490692	0.0231692560461	0.727272727273	CCDC124 U2SURP RBM17 RBM10 TRIR HTATSF1 SCAF8 PCNP	smooth muscle; smooth muscle cells[>=Medium]
HPA:0010012	0.0258073078917	0.636363636364	CCDC124 DNAJC8 U2SURP HTATSF1 RBM17 SCAF8 PCNP	adipose tissue; adipocytes[>=Medium]
HPA:0381212	0.02611325079	0.363636363636	HTATSF1 PCNP U2SURP SCAF8	placenta; syncytiotrophoblasts - cell body[>=Medium]
HPA:0050012	0.0269140433617	0.545454545455	CCDC124 U2SURP HTATSF1 RBM17 PCNP SCAF8	breast; adipocytes[>=Medium]
HPA:0160252	0.0276027453965	0.636363636364	CCDC124 U2SURP RBM17 RBM10 HTATSF1 SCAF8 PCNP	endometrium 1; cells in endometrial stroma[>=Medium]
HPA:0301362	0.0280845686802	0.454545454545	RBM17 HTATSF1 PCNP U2SURP SCAF8	lung; alveolar cells type I[>=Medium]
HPA:0020053	0.0311152757565	0.636363636364	U2SURP RBM17 RBM10 TRIR HTATSF1 SCAF8 PCNP	adrenal gland; glandular cells[High]
HPA:0330222	0.0322877616595	0.818181818182	DNAJC8 U2SURP RBM17 RBM10 TRIR HTATSF1 SCAF8 PCNP CCDC124	oral mucosa; squamous epithelial cells[>=Medium]
HPA:0360052	0.0363552516873	0.818181818182	DNAJC8 U2SURP RBM17 RBM10 TRIR HTATSF1 SCAF8 PCNP CCDC124	parathyroid gland; glandular cells[>=Medium]
HPA:0461492	0.0413639111053	0.272727272727	RBM17 U2SURP PCNP	skin 1; vascular mural cells[>=Medium]
HPA:0381211	0.0427094017745	0.363636363636	HTATSF1 PCNP U2SURP SCAF8	placenta; syncytiotrophoblasts - cell body[>=Low]
HPA:0471492	0.0427150544502	0.272727272727	RBM17 U2SURP PCNP	skin 2; vascular mural cells[>=Medium]
HPA:0550053	0.0468680252308	0.636363636364	CCDC124 U2SURP RBM17 RBM10 HTATSF1 SCAF8 PCNP	stomach 2; glandular cells[High]
HPA:0250123	0.0484907235618	0.363636363636	RBM17 SCAF8 RBM10 U2SURP	hippocampus; glial cells[High]
HPA:0100202	0.0495176832329	0.636363636364	CCDC124 U2SURP RBM17 RBM10 HTATSF1 SCAF8 PCNP	cerebral cortex; endothelial cells[>=Medium]

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
RBM17	CHERP	1.0	0.908
RBM17	U2SURP	1.0	0.888
U2SURP	CHERP	0.999	0.956
RBM10	RBM17	0.998	0.392
AGGF1	HTATSF1	0.988	0.09
RBM17	DNAJC8	0.987	0.456
RBM10	AGGF1	0.985	0.144
RBM10	CHERP	0.985	0.312
RBM10	TRIR	0.981	0.108
RBM10	PCNP	0.98	0.078
CHERP	DNAJC8	0.972	0.312	structurally_consistent (dimer)
CCDC124	RBM10	0.966	0.106
TRIR	CHERP	0.963	0.266
PCNP	TRIR	0.963	0.236
RBM17	SCAF8	0.962	0.256
PCNP	DNAJC8	0.962	0.294
RBM10	HTATSF1	0.962	0.324
SCAF8	HTATSF1	0.961	0.16
AGGF1	RBM17	0.959	0.12
SCAF8	CHERP	0.953	0.52
RBM10	U2SURP	0.953	0.25
SCAF8	DNAJC8	0.952	0.132
U2SURP	DNAJC8	0.951	0.256
TRIR	RBM17	0.951	0.278
SCAF8	U2SURP	0.937	0.408
RBM10	SCAF8	0.919	0.288
TRIR	DNAJC8	0.907	0.374
TRIR	SCAF8	0.906	0.276
RBM10	DNAJC8	0.903	0.140379310345
PCNP	RBM17	0.879	0.154
RBM17	HTATSF1	0.865	0.364
AGGF1	U2SURP	0.855	0.184
AGGF1	CHERP	0.845	0.318
PCNP	AGGF1	0.844	0.094
HTATSF1	DNAJC8	0.836	0.368
PCNP	SCAF8	0.835	0.14
HTATSF1	U2SURP	0.821	0.232
AGGF1	SCAF8	0.812	0.176
HTATSF1	CHERP	0.785	0.228
TRIR	U2SURP	0.727	0.132
TRIR	AGGF1	0.708	0.114
CCDC124	TRIR	0.592	0.13
AGGF1	DNAJC8	0.558	0.146
CCDC124	RBM17	0.558	0.128
CCDC124	PCNP	0.387	0.258
CCDC124	SCAF8	0.289	0.066
PCNP	CHERP	0.256	0.176
CCDC124	DNAJC8	0.243	0.202
TRIR	HTATSF1	0.165	0.13
PCNP	HTATSF1	0.062	0.116
PCNP	U2SURP	0.059	0.142
CCDC124	AGGF1	0.02	0.134
CCDC124	U2SURP	0.003	0.132
CCDC124	HTATSF1	0.002	0.038
CCDC124	CHERP	0.001	0.216

Related Complexes

Genename	Complexes
RBM10	huMAP3_00625.1 huMAP3_01885.1 huMAP3_07493.1 huMAP3_07523.1 huMAP3_07735.1 huMAP3_08220.1 huMAP3_09300.1 huMAP3_09594.1 huMAP3_10359.1 huMAP3_11021.1 huMAP3_11912.1
U2SURP	huMAP3_06609.1 huMAP3_08220.1 huMAP3_09594.1 huMAP3_10359.1
RBM17	huMAP3_02391.1 huMAP3_04865.1 huMAP3_06609.1 huMAP3_08220.1 huMAP3_08230.1 huMAP3_09300.1 huMAP3_09594.1 huMAP3_10359.1 huMAP3_11021.1 huMAP3_11912.1
SCAF8	huMAP3_02391.1 huMAP3_06609.1 huMAP3_08220.1 huMAP3_08230.1 huMAP3_08659.1 huMAP3_09300.1 huMAP3_09569.1 huMAP3_09594.1 huMAP3_10359.1 huMAP3_11021.1 huMAP3_11912.1 huMAP3_11918.1
AGGF1	huMAP3_01885.1 huMAP3_06195.1 huMAP3_07735.1 huMAP3_09300.1 huMAP3_09594.1 huMAP3_10359.1 huMAP3_11021.1 huMAP3_11912.1
HTATSF1	huMAP3_04549.1 huMAP3_06511.1 huMAP3_08220.1 huMAP3_08980.1 huMAP3_09594.1 huMAP3_10359.1
CHERP	huMAP3_06609.1 huMAP3_08220.1 huMAP3_09594.1 huMAP3_10359.1
DNAJC8	huMAP3_07290.1 huMAP3_09594.1 huMAP3_10359.1 huMAP3_11021.1 huMAP3_11912.1
CCDC124	huMAP3_00588.1 huMAP3_01744.1 huMAP3_02373.1 huMAP3_05711.1 huMAP3_06888.1 huMAP3_07523.1 huMAP3_07909.1 huMAP3_08025.1 huMAP3_08220.1 huMAP3_08526.1 huMAP3_09594.1 huMAP3_09754.1 huMAP3_09891.1 huMAP3_10359.1 huMAP3_10631.1 huMAP3_10719.1 huMAP3_11021.1 huMAP3_11099.1 huMAP3_11111.1 huMAP3_14270.1 huMAP3_14559.1
PCNP	huMAP3_00625.1 huMAP3_07523.1 huMAP3_07735.1 huMAP3_08220.1 huMAP3_09300.1 huMAP3_09594.1 huMAP3_10359.1 huMAP3_11021.1 huMAP3_11912.1
TRIR	huMAP3_00625.1 huMAP3_07493.1 huMAP3_07523.1 huMAP3_07735.1 huMAP3_08220.1 huMAP3_09300.1 huMAP3_09594.1 huMAP3_10359.1 huMAP3_11021.1 huMAP3_11912.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_09594.1

Complex Portal: CPX-13000