hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09597.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RGPD1 | RANBP2-like and GRIP domain-containing protein 1 (Ran-binding protein 2-like 6) (RanBP2-like 6) (RanBP2L6) | 3 | UniProt NCBI |
| RAN | GTP-binding nuclear protein Ran (EC 3.6.5.-) (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein) | 5 | UniProt NCBI |
| NUSAP1 | Nucleolar and spindle-associated protein 1 (NuSAP) | 5 | UniProt NCBI |
| RGPD2 | RANBP2-like and GRIP domain-containing protein 2 (Ran-binding protein 2-like 2) (RanBP2-like 2) (RanBP2L2) | 3 | UniProt NCBI |
| NUTF2 | Nuclear transport factor 2 (NTF-2) (Placental protein 15) (PP15) | 5 | UniProt NCBI |
| RCC1 | Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9615933 | 0.00418294558639 | 0.4 | RCC1 RAN | Postmitotic nuclear pore complex (NPC) reformation |
| REAC:R-HSA-180746 | 0.00704059925156 | 0.4 | RCC1 RAN | Nuclear import of Rev protein |
| REAC:R-HSA-165054 | 0.00750894366662 | 0.4 | RCC1 RAN | Rev-mediated nuclear export of HIV RNA |
| REAC:R-HSA-177243 | 0.00849065158197 | 0.4 | RCC1 RAN | Interactions of Rev with host cellular proteins |
| WP:WP4657 | 0.0287269200827 | 0.4 | RCC1 RAN | 22q11 2 copy number variation syndrome |
| REAC:R-HSA-2995410 | 0.0333121022189 | 0.4 | RCC1 RAN | Nuclear Envelope (NE) Reassembly |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| RAN | RCC1 | 1.0 | 0.16 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 fraction treiber_WMM |
| NUSAP1 | RCC1 | 0.998 | 0.212 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM |
| RGPD1 | RAN | 0.996 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| RAN | RGPD2 | 0.995 | 0.214 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| RAN | NUSAP1 | 0.995 | 0.282 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction |
| RGPD1 | RCC1 | 0.995 | bioplex3_HEK293 bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only | |
| RAN | NUTF2 | 0.986 | 0.228 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction treiber_WMM |
| RGPD2 | RCC1 | 0.955 | 0.14 | bioplex_WMM bioplex3_WMM WMM_only |
| RGPD1 | NUSAP1 | 0.955 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| RGPD2 | NUTF2 | 0.266 | 0.096 | bioplex_WMM bioplex3_WMM WMM_only |
| NUTF2 | RCC1 | 0.249 | 0.078 | bioplex_WMM Guru bioplex3_WMM fraction |
| NUSAP1 | RGPD2 | 0.202 | 0.136 | bioplex_WMM bioplex3_WMM WMM_only |
| RGPD1 | RGPD2 | 0.055 | bioplex3_WMM WMM_only | |
| RGPD1 | NUTF2 | 0.034 | bioplex3_WMM WMM_only | |
| NUSAP1 | NUTF2 | 0.014 | 0.146 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes