hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_09603.1

Complex Portal: CPX-24181

Confidence: Moderate High

Genename	Protein Name	Uniprot Annotation Score	Links
TUBB8	Tubulin beta-8 chain (Tubulin beta 8 class VIII)	5	UniProt NCBI
DNAJA1	DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2)	5	UniProt NCBI
TUBB	Tubulin beta chain (Tubulin beta-5 chain)	5	UniProt NCBI
CAD	Multifunctional protein CAD (Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase) [Includes: Glutamine-dependent carbamoyl phosphate synthase (EC 6.3.5.5); Glutamine amidotransferase (GATase) (GLNase) (EC 3.5.1.2); Ammonium-dependent carbamoyl phosphate synthase (CPS) (CPSase) (EC 6.3.4.16); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)]	5	UniProt NCBI
EML6	Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like)	3	UniProt NCBI
RPS27	Small ribosomal subunit protein eS27 (40S ribosomal protein S27) (Metallopan-stimulin 1) (MPS-1)	5	UniProt NCBI
TCP11L2	T-complex protein 11-like protein 2	4	UniProt NCBI
TUBB2B	Tubulin beta-2B chain	5	UniProt NCBI
TTC5	Tetratricopeptide repeat protein 5 (TPR repeat protein 5) (Stress-responsive activator of p300) (Protein Strap)	5	UniProt NCBI
TUBAL3	Tubulin alpha chain-like 3 (EC 3.6.5.-)	5	UniProt NCBI
TUBB4A	Tubulin beta-4A chain (Tubulin 5 beta) (Tubulin beta-4 chain)	5	UniProt NCBI
TUBA1A	Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]	5	UniProt NCBI
TUBA4B	Putative tubulin-like protein alpha-4B (EC 3.6.5.-) (Alpha-tubulin 4B)	3	UniProt NCBI
TUBA1B	Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]	5	UniProt NCBI
TUBB6	Tubulin beta-6 chain (Tubulin beta class V)	5	UniProt NCBI
MADD	MAP kinase-activating death domain protein (Differentially expressed in normal and neoplastic cells) (Insulinoma glucagonoma clone 20) (Rab3 GDP/GTP exchange factor) (RabGEF) (Rab3 GDP/GTP exchange protein) (Rab3GEP)	5	UniProt NCBI
TUBB2A	Tubulin beta-2A chain (Tubulin beta class IIa)	5	UniProt NCBI
TUBB3	Tubulin beta-3 chain (Tubulin beta-4 chain) (Tubulin beta-III)	5	UniProt NCBI
TBCD	Tubulin-specific chaperone D (Beta-tubulin cofactor D) (tfcD) (SSD-1) (Tubulin-folding cofactor D)	5	UniProt NCBI
CAPS	Calcyphosin (Calcyphosine)	5	UniProt NCBI
TUBA1C	Tubulin alpha-1C chain (EC 3.6.5.-) (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain]	5	UniProt NCBI
ARL2	ADP-ribosylation factor-like protein 2	5	UniProt NCBI
FAS	Tumor necrosis factor receptor superfamily member 6 (Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor) (CD antigen CD95)	5	UniProt NCBI
TCP11L1	T-complex protein 11-like protein 1	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-389977	2.96504161164e-27	0.521739130435	TUBAL3 TUBB2B TBCD TUBB4A TUBA1A TUBB6 TUBB3 TUBB2A TUBA1B ARL2 TUBA1C TUBA4B	Post-chaperonin tubulin folding pathway
REAC:R-HSA-190840	8.51348121183e-26	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
REAC:R-HSA-190872	2.02042819891e-25	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Transport of connexons to the plasma membrane
REAC:R-HSA-9619483	1.1861565298e-23	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Activation of AMPK downstream of NMDARs
REAC:R-HSA-190861	5.70156926771e-23	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Gap junction assembly
REAC:R-HSA-5626467	9.17893581906e-23	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	RHO GTPases activate IQGAPs
REAC:R-HSA-9668328	9.17893581906e-23	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Sealing of the nuclear envelope (NE) by ESCRT-III
REAC:R-HSA-3371497	4.43528984672e-22	0.521739130435	TUBAL3 TUBB2B TUBB4A TUBA4B TUBB8 TUBB6 TUBB2A TUBA1B DNAJA1 TUBA1C TUBA1A TUBB3	HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
REAC:R-HSA-8955332	3.17090533436e-21	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Carboxyterminal post-translational modifications of tubulin
REAC:R-HSA-9609736	3.17090533436e-21	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Assembly and cell surface presentation of NMDA receptors
REAC:R-HSA-190828	4.41328625626e-21	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Gap junction trafficking
WP:WP2359	6.01200958225e-21	0.521739130435	TUBAL3 TUBB TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Parkin ubiquitin proteasomal system pathway
REAC:R-HSA-157858	6.08269888096e-21	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Gap junction trafficking and regulation
REAC:R-HSA-9646399	8.30674974922e-21	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Aggrephagy
REAC:R-HSA-389960	9.75683955714e-21	0.434782608696	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Formation of tubulin folding intermediates by CCT/TriC
WP:WP2272	2.95789295069e-20	0.478260869565	TUBAL3 TUBB TUBB4A TUBB6 TUBB8 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Pathogenic Escherichia coli infection
REAC:R-HSA-437239	3.49429907522e-20	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Recycling pathway of L1
REAC:R-HSA-6811436	9.75441173707e-20	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	COPI-independent Golgi-to-ER retrograde traffic
REAC:R-HSA-389958	1.91471787228e-19	0.434782608696	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding
REAC:R-HSA-983189	2.49212942378e-19	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Kinesins
REAC:R-HSA-380320	5.73224413282e-19	0.521739130435	TUBAL3 TUBB TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Recruitment of NuMA to mitotic centrosomes
REAC:R-HSA-391251	7.58280390879e-19	0.521739130435	TUBAL3 TUBB2B TBCD TUBB4A TUBA1A TUBB6 TUBB3 TUBB2A TUBA1B ARL2 TUBA1C TUBA4B	Protein folding
KEGG:04540	1.2562724936e-18	0.478260869565	TUBAL3 TUBB TUBB4A TUBB6 TUBB8 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Gap junction
REAC:R-HSA-2995410	3.31293749827e-18	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Nuclear Envelope (NE) Reassembly
REAC:R-HSA-438064	3.94928970251e-18	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Post NMDA receptor activation events
REAC:R-HSA-1445148	4.69474236325e-18	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Translocation of SLC2A4 (GLUT4) to the plasma membrane
REAC:R-HSA-9648025	1.01771641348e-17	0.521739130435	TUBAL3 RPS27 TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	EML4 and NUDC in mitotic spindle formation
REAC:R-HSA-9663891	1.2551650185e-17	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Selective autophagy
REAC:R-HSA-8852276	1.46646804245e-17	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	The role of GTSE1 in G2/M progression after G2 checkpoint
REAC:R-HSA-2500257	2.39682995766e-17	0.521739130435	TUBAL3 RPS27 TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Resolution of Sister Chromatid Cohesion
REAC:R-HSA-442755	2.67475642384e-17	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Activation of NMDA receptors and postsynaptic events
REAC:R-HSA-5663220	7.09221586092e-17	0.521739130435	TUBAL3 RPS27 TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	RHO GTPases Activate Formins
GO:0005200	8.88497840587e-17	0.521739130435	TUBAL3 TUBB TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	structural constituent of cytoskeleton
REAC:R-HSA-68877	9.3188380563e-17	0.565217391304	TUBAL3 RPS27 TUBB2B TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB	Mitotic Prometaphase
REAC:R-HSA-6811434	1.54103383455e-16	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	COPI-dependent Golgi-to-ER retrograde traffic
REAC:R-HSA-6807878	2.22419108087e-16	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	COPI-mediated anterograde transport
REAC:R-HSA-373760	4.47279413951e-16	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	L1CAM interactions
KEGG:04145	1.62139240622e-15	0.478260869565	TUBAL3 TUBB TUBB4A TUBB6 TUBB8 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Phagosome
REAC:R-HSA-2132295	2.15370866753e-15	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	MHC class II antigen presentation
REAC:R-HSA-9609690	2.87458592155e-15	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	HCMV Early Events
GO:0005525	3.41603990342e-15	0.565217391304	TUBAL3 TUBB TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B ARL2 TUBA1C TUBA1A TUBB2B	GTP binding
REAC:R-HSA-2467813	4.27047276488e-15	0.521739130435	TUBAL3 RPS27 TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Separation of Sister Chromatids
REAC:R-HSA-8856688	5.00883609198e-15	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Golgi-to-ER retrograde transport
REAC:R-HSA-1632852	5.00883609198e-15	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Macroautophagy
REAC:R-HSA-5617833	5.92893071594e-15	0.521739130435	TUBAL3 TUBB TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Cilium Assembly
REAC:R-HSA-69275	5.92893071594e-15	0.521739130435	TUBAL3 TUBB TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	G2/M Transition
REAC:R-HSA-453274	6.74341224676e-15	0.521739130435	TUBAL3 TUBB TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Mitotic G2-G2/M phases
REAC:R-HSA-390466	8.89626029771e-15	0.434782608696	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Chaperonin-mediated protein folding
GO:0005874	1.50667928604e-14	0.608695652174	TUBAL3 TUBB TBCD TCP11L1 TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	microtubule
GO:0032561	1.54603420329e-14	0.565217391304	TUBAL3 TUBB TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B ARL2 TUBA1C TUBA1A TUBB2B	guanyl ribonucleotide binding
KEGG:04814	1.63516235163e-14	0.478260869565	TUBAL3 TUBB TUBB4A TUBB6 TUBB8 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Motor proteins
GO:0019001	1.65420045918e-14	0.565217391304	TUBAL3 TUBB TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B ARL2 TUBA1C TUBA1A TUBB2B	guanyl nucleotide binding
REAC:R-HSA-9612973	1.79234910093e-14	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Autophagy
REAC:R-HSA-9609646	1.94137721421e-14	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	HCMV Infection
KEGG:05130	2.00923205488e-14	0.478260869565	TUBAL3 TUBB TUBB4A TUBB6 TUBB8 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Pathogenic Escherichia coli infection
REAC:R-HSA-199977	2.10156241149e-14	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	ER to Golgi Anterograde Transport
REAC:R-HSA-68882	4.4537972634e-14	0.521739130435	TUBAL3 RPS27 TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Mitotic Anaphase
REAC:R-HSA-2555396	4.70258535737e-14	0.521739130435	TUBAL3 RPS27 TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Mitotic Metaphase and Anaphase
REAC:R-HSA-983231	6.02218365894e-14	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Factors involved in megakaryocyte development and platelet production
REAC:R-HSA-112314	6.46790627038e-14	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Neurotransmitter receptors and postsynaptic signal transmission
REAC:R-HSA-948021	1.67718410678e-13	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Transport to the Golgi and subsequent modification
REAC:R-HSA-1852241	5.62628272955e-13	0.521739130435	TUBAL3 TUBB TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Organelle biogenesis and maintenance
KEGG:05132	6.07458918171e-13	0.478260869565	TUBAL3 TUBB TUBB4A TUBB6 TUBB8 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Salmonella infection
REAC:R-HSA-6811442	6.07681337475e-13	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Intra-Golgi and retrograde Golgi-to-ER traffic
REAC:R-HSA-68886	7.48629523572e-13	0.565217391304	TUBAL3 RPS27 TUBB2B TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB	M Phase
REAC:R-HSA-112315	1.06663323079e-12	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Transmission across Chemical Synapses
KEGG:05012	1.18840523697e-12	0.478260869565	TUBAL3 TUBB TUBB4A TUBB6 TUBB8 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Parkinson disease
REAC:R-HSA-195258	1.36421040132e-12	0.521739130435	TUBAL3 RPS27 TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	RHO GTPase Effectors
KEGG:05020	1.63710604249e-12	0.478260869565	TUBAL3 TUBB TUBB4A TUBB6 TUBB8 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Prion disease
WP:WP2059	1.7382743637e-12	0.478260869565	TUBAL3 TUBB TUBB4A TUBB6 TUBB8 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Alzheimer 39 s disease and miRNA effects
WP:WP5124	1.7382743637e-12	0.478260869565	TUBAL3 TUBB TUBB4A TUBB6 TUBB8 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Alzheimer 39 s disease
REAC:R-HSA-5620924	1.87923247541e-12	0.347826086957	TUBB2B TUBB6 TUBB4A TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A	Intraflagellar transport
REAC:R-HSA-389957	2.4414126229e-12	0.304347826087	TUBB2B TUBB6 TUBB4A TUBB3 TUBA1C TUBB2A TUBA1A	Prefoldin mediated transfer of substrate to CCT/TriC
KEGG:05016	4.97619018729e-12	0.478260869565	TUBAL3 TUBB TUBB4A TUBB6 TUBB8 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Huntington disease
GO:0035639	6.17900721542e-12	0.608695652174	TUBAL3 TUBB2B CAD TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B ARL2 TUBA1C TUBA1A TUBB	purine ribonucleoside triphosphate binding
GO:0099513	6.60632658599e-12	0.608695652174	TUBAL3 TUBB TBCD TCP11L1 TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	polymeric cytoskeletal fiber
KEGG:05014	3.52666334675e-11	0.478260869565	TUBAL3 TUBB TUBB4A TUBB6 TUBB8 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Amyotrophic lateral sclerosis
GO:0032555	3.68901396641e-11	0.608695652174	TUBAL3 TUBB2B CAD TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B ARL2 TUBA1C TUBA1A TUBB	purine ribonucleotide binding
REAC:R-HSA-69278	3.89899371561e-11	0.565217391304	TUBAL3 RPS27 TUBB2B TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB	Cell Cycle, Mitotic
REAC:R-HSA-446203	4.19716903466e-11	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Asparagine N-linked glycosylation
GO:0032553	4.65612280488e-11	0.608695652174	TUBAL3 TUBB2B CAD TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B ARL2 TUBA1C TUBA1A TUBB	ribonucleotide binding
KEGG:05010	5.96824436756e-11	0.478260869565	TUBAL3 TUBB TUBB4A TUBB6 TUBB8 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Alzheimer disease
GO:0000226	6.37169725682e-11	0.608695652174	TUBAL3 TUBB TBCD TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B ARL2 TUBA1C TUBA1A TUBB2B	microtubule cytoskeleton organization
REAC:R-HSA-112316	7.39689208374e-11	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Neuronal System
GO:0017076	2.03312201864e-10	0.608695652174	TUBAL3 TUBB2B CAD TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B ARL2 TUBA1C TUBA1A TUBB	purine nucleotide binding
GO:0099512	3.46122344034e-10	0.608695652174	TUBAL3 TUBB TBCD TCP11L1 TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	supramolecular fiber
GO:0099081	4.11385613662e-10	0.608695652174	TUBAL3 TUBB TBCD TCP11L1 TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	supramolecular polymer
REAC:R-HSA-422475	4.53568341845e-10	0.521739130435	TUBAL3 RPS27 TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Axon guidance
KEGG:05022	5.06572986138e-10	0.478260869565	TUBAL3 TUBB TUBB4A TUBB6 TUBB8 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Pathways of neurodegeneration - multiple diseases
REAC:R-HSA-1640170	5.46367384941e-10	0.565217391304	TUBAL3 RPS27 TUBB2B TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB	Cell Cycle
REAC:R-HSA-9675108	6.98710100877e-10	0.521739130435	TUBAL3 RPS27 TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Nervous system development
REAC:R-HSA-5610787	7.8312876995e-10	0.347826086957	TUBB2B TUBB6 TUBB4A TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A	Hedgehog 'off' state
GO:0000166	1.38997096039e-09	0.608695652174	TUBAL3 TUBB2B CAD TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B ARL2 TUBA1C TUBA1A TUBB	nucleotide binding
GO:1901265	1.42139257926e-09	0.608695652174	TUBAL3 TUBB2B CAD TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B ARL2 TUBA1C TUBA1A TUBB	nucleoside phosphate binding
REAC:R-HSA-9824446	1.56406869345e-09	0.565217391304	TUBAL3 RPS27 TUBB2B TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB	Viral Infection Pathways
GO:0015630	1.98649153088e-09	0.695652173913	TUBAL3 TUBB2B TBCD TUBB3 TCP11L1 TUBB4A TUBA4B TUBB8 TUBB6 TUBB2A TUBA1B DNAJA1 ARL2 TUBA1C TUBA1A TUBB	microtubule cytoskeleton
REAC:R-HSA-2262752	2.22953304237e-09	0.565217391304	TUBAL3 TUBB2B TUBB3 TUBB4A TUBA4B TUBB8 TUBB6 TUBB2A TUBA1B DNAJA1 TUBA1C TUBA1A RPS27	Cellular responses to stress
REAC:R-HSA-8953897	2.51794802314e-09	0.565217391304	TUBAL3 TUBB2B TUBB3 TUBB4A TUBA4B TUBB8 TUBB6 TUBB2A TUBA1B DNAJA1 TUBA1C TUBA1A RPS27	Cellular responses to stimuli
GO:1901363	3.59247834135e-09	0.608695652174	TUBAL3 TUBB2B CAD TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B ARL2 TUBA1C TUBA1A TUBB	heterocyclic compound binding
GO:0005198	3.96696887308e-09	0.565217391304	TUBAL3 RPS27 TUBB2B TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB	structural molecule activity
REAC:R-HSA-5358351	4.74397271289e-09	0.347826086957	TUBB2B TUBB6 TUBB4A TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A	Signaling by Hedgehog
GO:0097367	5.41353040142e-09	0.608695652174	TUBAL3 TUBB2B CAD TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B ARL2 TUBA1C TUBA1A TUBB	carbohydrate derivative binding
GO:0007017	7.16022246137e-09	0.608695652174	TUBAL3 TUBB TBCD TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B ARL2 TUBA1C TUBA1A TUBB2B	microtubule-based process
REAC:R-HSA-194315	1.04746270599e-08	0.521739130435	TUBAL3 RPS27 TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Signaling by Rho GTPases
REAC:R-HSA-9716542	1.35298197085e-08	0.521739130435	TUBAL3 RPS27 TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Signaling by Rho GTPases, Miro GTPases and RHOBTB3
REAC:R-HSA-5663205	2.0938336437e-08	0.565217391304	TUBAL3 RPS27 TUBB2B TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB	Infectious disease
HP:0025102	2.90944945734e-08	0.173913043478	TUBB3 TUBA1A TUBB TUBB2B	Dysgenesis of the basal ganglia
REAC:R-HSA-109582	3.41736395519e-08	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Hemostasis
GO:0043168	5.82453786342e-08	0.608695652174	TUBAL3 TUBB2B CAD TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B ARL2 TUBA1C TUBA1A TUBB	anion binding
REAC:R-HSA-199991	8.69541825759e-08	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Membrane Trafficking
CORUM:6715	1.07739615662e-07	0.130434782609	TBCD TUBB ARL2	TBCD-ARL2-tubulin(beta)-TBCE complex
CORUM:6713	1.07739615662e-07	0.130434782609	TBCD TUBB ARL2	TBCD-ARL2-tubulin(beta) complex
CORUM:6703	1.07739615662e-07	0.130434782609	TBCD TUBB TUBA1A	TBCD-tubulin(alpha)-tubulin(beta) complex
REAC:R-HSA-5653656	1.54987956648e-07	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Vesicle-mediated transport
GO:0099080	1.61507728217e-07	0.608695652174	TUBAL3 TUBB TBCD TCP11L1 TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	supramolecular complex
GO:0000278	3.45577621567e-07	0.565217391304	TUBAL3 TUBB TBCD TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	mitotic cell cycle
REAC:R-HSA-1266738	3.52280461249e-07	0.521739130435	TUBAL3 RPS27 TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Developmental Biology
REAC:R-HSA-1280218	4.15297312285e-07	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Adaptive Immune System
GO:0043167	8.64604539986e-07	0.695652173913	TUBAL3 RPS27 CAD CAPS TUBB4A TUBB TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B ARL2 TUBA1C TUBA1A TUBB2B	ion binding
GO:0005856	1.10255437424e-06	0.695652173913	TUBAL3 TUBB2B TBCD TUBB3 TCP11L1 TUBB4A TUBA4B TUBB8 TUBB6 TUBB2A TUBA1B DNAJA1 ARL2 TUBA1C TUBA1A TUBB	cytoskeleton
GO:0045171	1.17505406339e-06	0.304347826087	TUBB TUBB6 TUBB4A TUBB8 TUBB3 TUBB2A TUBB2B	intercellular bridge
GO:0007049	1.20437048899e-06	0.652173913043	TUBAL3 TUBB TBCD MADD TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B ARL2 TUBA1C TUBA1A TUBB2B	cell cycle
GO:0007010	3.8011645202e-06	0.608695652174	TUBAL3 TUBB TBCD TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B ARL2 TUBA1C TUBA1A TUBB2B	cytoskeleton organization
HP:0020214	4.25571481866e-06	0.130434782609	TUBB3 TUBB2B TUBA1A	Startle-induced seizure
GO:0036094	4.79195540728e-06	0.695652173913	TUBAL3 RPS27 CAD CAPS TUBB4A TUBB TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B ARL2 TUBA1C TUBA1A TUBB2B	small molecule binding
REAC:R-HSA-392499	7.96324489561e-06	0.608695652174	TUBAL3 RPS27 TBCD TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B ARL2 TUBA1C TUBA1A TUBB2B	Metabolism of proteins
REAC:R-HSA-1643685	1.62454117686e-05	0.565217391304	TUBAL3 RPS27 TUBB2B TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB	Disease
HP:0012502	1.70053843986e-05	0.130434782609	TUBB3 TUBB2B TUBA1A	Abnormality of the internal capsule
HP:0001491	4.24698192546e-05	0.130434782609	TUBB3 TUBB2B TUBA1A	Congenital fibrosis of extraocular muscles
HP:0025721	4.24698192546e-05	0.130434782609	TUBB3 TUBB2B TUBA1A	Limited vertical extraocular movement
HP:0030534	4.24698192546e-05	0.130434782609	TUBB3 TUBB2B TUBA1A	Abnormal best corrected visual acuity test
HP:0012241	4.24698192546e-05	0.130434782609	TUBB3 TUBB2B TUBA1A	Levator palpebrae superioris atrophy
HP:0025309	4.24698192546e-05	0.130434782609	TUBB3 TUBB2B TUBA1A	Abnormal pupil shape
HP:0007831	4.24698192546e-05	0.130434782609	TUBB3 TUBB2B TUBA1A	Nonprogressive restrictive external ophthalmoplegia
HP:3000072	4.24698192546e-05	0.130434782609	TUBB3 TUBB2B TUBA1A	Abnormal levator palpebrae superioris morphology
HP:0001477	4.24698192546e-05	0.130434782609	TUBB3 TUBB2B TUBA1A	Compensatory chin elevation
CORUM:6455	7.49713811273e-05	0.0869565217391	TBCD ARL2	ARL2-TBCD complex
CORUM:6697	7.49713811273e-05	0.0869565217391	TBCD ARL2	ARL2-TBCD complex
HP:0032398	8.48524458287e-05	0.130434782609	TUBB3 TUBB2B TUBA1A	Dysgyria
HP:0002365	0.000148346231127	0.217391304348	TUBB3 TUBB2A TUBA1A TUBB TUBB2B	Hypoplasia of the brainstem
HP:0007362	0.000148346231127	0.217391304348	TUBB3 TUBB2A TUBA1A TUBB TUBB2B	Aplasia/Hypoplasia of the brainstem
GO:0072686	0.000167322882296	0.304347826087	TUBB TUBB6 TUBB4A TUBB8 TUBB3 TUBB2A TUBB2B	mitotic spindle
HP:0000542	0.000237099331014	0.130434782609	TUBB3 TUBB2B TUBA1A	Impaired ocular adduction
REAC:R-HSA-597592	0.000246319499406	0.478260869565	TUBAL3 TUBB2B TUBB4A TUBA1A TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA4B	Post-translational protein modification
HP:0025186	0.000355283929037	0.130434782609	TUBB3 TUBB2B TUBA1A	Marcus Gunn jaw winking synkinesis
HP:0008049	0.000355283929037	0.130434782609	TUBB3 TUBB2B TUBA1A	Abnormality of the extraocular muscles
HP:0011347	0.000355283929037	0.130434782609	TUBB3 TUBB2B TUBA1A	Abnormality of ocular abduction
REAC:R-HSA-162582	0.000629227789719	0.565217391304	TUBAL3 RPS27 TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B ARL2 TUBA1C TUBA1A TUBB2B	Signal Transduction
REAC:R-HSA-168256	0.000691244613432	0.521739130435	TUBAL3 TUBB TUBB4A TUBA4B TUBB8 TUBB6 TUBB3 TUBB2A TUBA1B TUBA1C TUBA1A TUBB2B	Immune System
HP:0009916	0.000927643105413	0.130434782609	TUBB3 TUBB2B TUBA1A	Anisocoria
HP:0032466	0.000927643105413	0.130434782609	TUBB3 TUBB2B TUBA1A	Aplasia of the olfactory bulb
HP:0007941	0.00120469823386	0.130434782609	TUBB3 TUBB2B TUBA1A	Limited extraocular movements
HP:0002539	0.00138613911624	0.173913043478	TUBB3 TUBB2A TUBB TUBB2B	Cortical dysplasia
HPA:0461423	0.00158841306721	0.173913043478	TUBA1B TUBA1C TUBA1A TUBB2A	skin 1; eccrine glands[High]
HP:0001338	0.00162085465013	0.173913043478	TUBB3 TUBA1A TUBB TUBB2B	Partial agenesis of the corpus callosum
HPA:0471423	0.00169859067572	0.130434782609	TUBA1B TUBA1A TUBA1C	skin 2; eccrine glands[High]
HP:0001180	0.0019126330519	0.130434782609	TUBB3 TUBB2B TUBA1A	Hand oligodactyly
HP:0030211	0.0019126330519	0.130434782609	TUBB3 TUBB2B TUBA1A	Slow pupillary light response
KEGG:04210	0.00208884428063	0.173913043478	TUBAL3 TUBA1C TUBA1A TUBA1B	Apoptosis
HP:0002363	0.00212367860039	0.260869565217	TBCD TUBB TUBB3 TUBB2A TUBA1A TUBB2B	Abnormal brainstem morphology
HP:0001357	0.00229729735681	0.217391304348	TUBB3 MADD TBCD TUBB2B TUBA1A	Plagiocephaly
HP:0031705	0.00235159379676	0.130434782609	TUBB3 TUBB2B TUBA1A	Compensatory head posture
HP:0031882	0.002852575954	0.130434782609	TUBB3 TUBB2B TUBA1A	Agyria
HP:0020207	0.002852575954	0.130434782609	TUBB3 TUBB2B TUBA1A	Reflex seizure
KEGG:04530	0.00371245398336	0.173913043478	TUBAL3 TUBA1C TUBA1A TUBA1B	Tight junction
HPA:0500703	0.00371740422391	0.217391304348	TUBB3 TUBA1B TUBA1C TUBB TUBA1A	soft tissue 1; peripheral nerve[High]
HP:0030532	0.00405658098876	0.130434782609	TUBB3 TUBB2B TUBA1A	Visual acuity test abnormality
HP:0000473	0.0047061247542	0.173913043478	TUBB3 TUBA1A TUBB2B TUBB4A	Torticollis
HP:0030588	0.00476755014475	0.130434782609	TUBB3 TUBB2B TUBA1A	Abnormal visual field test
HP:0000616	0.00555643335806	0.130434782609	TUBB3 TUBB2B TUBA1A	Miosis
HP:0011006	0.00558299687191	0.173913043478	TUBB3 TUBA1A TUBB2B TUBB4A	Abnormal morphology of the musculature of the neck
HP:0009380	0.00693344461701	0.173913043478	TUBB3 TUBA1A RPS27 TUBB2B	Aplasia of the fingers
HP:0011097	0.0077618171038	0.217391304348	TUBB3 TUBB2A TBCD TUBB2B TUBA1A	Epileptic spasm
HPA:0461493	0.00836246438247	0.173913043478	TUBA1B TUBA1C TUBA1A TUBB2A	skin 1; vascular mural cells[High]
HP:0007695	0.00842979799021	0.130434782609	TUBB3 TUBB2B TUBA1A	Abnormal pupillary light reflex
GO:0005819	0.0138487235364	0.304347826087	TUBB TUBB6 TUBB4A TUBB8 TUBB3 TUBB2A TUBB2B	spindle
HP:0002536	0.0141611130931	0.260869565217	TUBB TTC5 TUBB3 TUBB2A TUBA1A TUBB2B	Abnormal cortical gyration
HP:0000577	0.0155017835496	0.173913043478	TUBB3 MADD TUBB2B TUBA1A	Exotropia
HPA:0461482	0.0165069868821	0.173913043478	TUBA1B ARL2 TUBA1A TUBA1C	skin 1; sebaceous glands[>=Medium]
HP:0040327	0.018587245017	0.130434782609	TUBB3 TUBB2B TUBA1A	Abnormal morphology of the olfactory bulb
HP:0000657	0.0190790522395	0.173913043478	TUBB3 TUBA1A TUBB2B TUBB4A	Oculomotor apraxia
HP:0012179	0.0214975526755	0.173913043478	TUBB3 TUBA1A TUBB2B TUBB4A	Craniofacial dystonia
HP:0025668	0.0224485578935	0.304347826087	RPS27 TUBB2B MADD TUBB4A TUBB3 TUBA1A TUBB	Abnormal neck morphology
HP:0012165	0.0225147919734	0.130434782609	TUBB3 TUBB2B TUBA1A	Oligodactyly
HP:0020049	0.0250643227665	0.173913043478	TUBB3 MADD TUBB2B TUBA1A	Exodeviation
HPA:0461422	0.0274775879593	0.173913043478	TUBA1B TUBA1C TUBA1A TUBB2A	skin 1; eccrine glands[>=Medium]
HPA:0471422	0.0279037520979	0.130434782609	TUBA1B TUBA1A TUBA1C	skin 2; eccrine glands[>=Medium]
HPA:0470673	0.0291093908021	0.217391304348	TUBA1B ARL2 TUBA1C TUBA1A TUBB2A	skin 2; melanocytes[High]
HPA:0461492	0.0299294057755	0.173913043478	TUBA1B TUBA1C TUBA1A TUBB2A	skin 1; vascular mural cells[>=Medium]
HPA:0471492	0.031212993996	0.173913043478	TUBA1B TUBA1C TUBA1A TUBB2A	skin 2; vascular mural cells[>=Medium]
HPA:0570763	0.0321092104377	0.304347826087	TUBB TUBB6 TUBB4A TUBB3 TUBB2A ARL2 TUBB2B	testis; pachytene spermatocytes[High]
HP:0004373	0.0334801144133	0.173913043478	TUBB3 TUBA1A TUBB2B TUBB4A	Focal dystonia
HP:0000464	0.0345255080794	0.304347826087	RPS27 TUBB2B MADD TUBB4A TUBB3 TUBA1A TUBB	Abnormality of the neck
HPA:0461481	0.0367487179991	0.173913043478	TUBA1B ARL2 TUBA1A TUBA1C	skin 1; sebaceous glands[>=Low]
HPA:0471402	0.0403543280617	0.130434782609	TUBA1B TUBA1A TUBA1C	skin 2; cells in corneal layer[>=Medium]
HP:0002079	0.0411849468778	0.260869565217	TBCD TUBB TUBB3 TUBB2A TUBA1A TUBB2B	Hypoplasia of the corpus callosum
HPA:0461483	0.0435357301852	0.130434782609	TUBA1B TUBA1A TUBA1C	skin 1; sebaceous glands[High]
HP:0002269	0.0452603305335	0.260869565217	TUBB TTC5 TUBB3 TUBB2A TUBA1A TUBB2B	Abnormality of neuronal migration
HPA:0470202	0.0452900909846	0.260869565217	TUBB TUBA1A TUBB2A TUBA1C TUBA1B ARL2	skin 2; endothelial cells[>=Medium]
HP:0008527	0.0469378194774	0.130434782609	TUBB3 TUBB2B TUBA1A	Congenital sensorineural hearing impairment
REAC:R-HSA-380259	0.0471083437265	0.130434782609	TUBA1A TUBB TUBB4A	Loss of Nlp from mitotic centrosomes
REAC:R-HSA-380284	0.0471083437265	0.130434782609	TUBA1A TUBB TUBB4A	Loss of proteins required for interphase microtubule organization from the centrosome
HPA:0461443	0.0473918352996	0.217391304348	TUBA1B TUBA1C TUBB TUBB2A TUBA1A	skin 1; fibrohistiocytic cells[High]
HP:0001320	0.0496222622992	0.217391304348	TUBB3 TUBB2A TUBA1A TUBB TUBB2B	Cerebellar vermis hypoplasia
HPA:0471472	0.0499647851127	0.260869565217	TUBB TUBA1A TUBB2A TUBA1C TUBA1B ARL2	skin 2; lymphocytes[>=Medium]

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
ARL2	TBCD	1.0	0.2
TUBB	TUBA1C	1.0	0.974	mixed_interface
DNAJA1	TUBB	0.999	0.374
TUBB	TBCD	0.999	0.4
TCP11L1	TUBB	0.999	0.204105263158
TUBB2A	TUBB6	0.999	0.526	structurally_consistent (dimer)
CAD	TUBA1C	0.998	0.508
ARL2	TUBB	0.998	0.098
TUBB2B	TBCD	0.998	0.286	structurally_consistent (dimer)
TCP11L1	TUBB2B	0.998	0.162	structurally_consistent (dimer)
TUBB6	TUBA1C	0.998	0.968	structurally_consistent (dimer)
TUBB	CAD	0.998	0.352
TUBA1C	TCP11L2	0.997		structurally_consistent (dimer)
TUBB8	TUBB	0.997	0.534	structurally_consistent (dimer)
TUBB2B	FAS	0.997	0.166
TUBA1B	TCP11L2	0.997		structurally_consistent (Q9BQE3) structurally_consistent (dimer)
TUBB2A	TUBA1C	0.996	0.552
TUBB2A	TUBB8	0.996	0.33	structurally_consistent (dimer)
TUBB6	TUBB	0.996	0.982	mutually_exclusive (Q9BQE3)
TUBB3	TUBB6	0.996	0.308	mutually_exclusive (Q9BQE3)
TUBB2A	TUBB4A	0.996	0.684	structurally_consistent (dimer)
TUBA1B	TUBB	0.995
TCP11L1	TUBB3	0.995	0.086
CAPS	TUBB2B	0.995	0.09
TUBB2A	FAS	0.995	0.204	structurally_consistent (P04350) structurally_consistent (dimer)
TUBB3	TUBB	0.995	0.394	mutually_exclusive (Q9BQE3)
TUBB2A	TBCD	0.995	0.148
TUBB4A	TBCD	0.993	0.3
TCP11L1	TTC5	0.993	0.04
TUBA1B	TUBA1C	0.993		structurally_consistent (dimer)
DNAJA1	TUBA1B	0.993		mutually_exclusive (P68366)
TUBA1C	TUBB4A	0.993	0.918
TUBB2A	TUBB	0.993	0.626	structurally_consistent (dimer)
TUBB	TUBB4A	0.992	0.938	structurally_consistent (dimer)
TUBB6	TUBB4A	0.992	0.798
TUBB	FAS	0.992	0.112	mutually_exclusive (P04350)
TUBB3	TUBA1C	0.992	0.404	structurally_consistent (dimer)
ARL2	TUBB2B	0.991	0.244	structurally_consistent (dimer)
TUBB3	TUBA1A	0.991		structurally_consistent (dimer)
TCP11L1	TUBB4A	0.991	0.138
TCP11L1	TUBA1C	0.991	0.382
TUBB2A	TTC5	0.991	0.188	structurally_consistent (dimer)
RPS27	TUBB6	0.99	0.256
TUBB2B	TTC5	0.99	0.184
RPS27	TUBB	0.99	0.49	structurally_consistent (Q3ZCM7)
TUBB2A	TUBB3	0.99	0.38	structurally_consistent (dimer)
TUBB2A	ARL2	0.989	0.164
TUBB4A	TUBB2B	0.988	0.650344827586
DNAJA1	TUBB3	0.988	0.32
RPS27	TUBA1C	0.988	0.262
TUBB	TTC5	0.985	0.236
TUBA1A	TCP11L2	0.985
TUBB3	CAD	0.984	0.332
TUBB2A	TCP11L1	0.983	0.106	structurally_consistent (dimer)
TUBA1A	TUBB4A	0.982
TUBB3	TUBB2B	0.979	0.398	structurally_consistent (dimer)
TUBB8	TUBB2B	0.979	0.284	structurally_consistent (dimer)
TUBA1A	TUBB	0.979
TUBAL3	TCP11L2	0.978		structurally_consistent (dimer)
TUBA1B	TUBB6	0.977
TUBB6	TUBB2B	0.976	0.63	structurally_consistent (dimer)
TUBB6	FAS	0.975	0.224768
RPS27	TUBB4A	0.975	0.264	structurally_consistent (Q3ZCM7)
TUBB8	TUBB6	0.973	0.546	structurally_consistent (dimer)
TUBB8	TUBA1A	0.971		structurally_consistent (dimer)
TUBB3	EML6	0.97
TUBB8	TUBB4A	0.969	0.554	structurally_consistent (dimer)
DNAJA1	TUBA1A	0.968
TUBA1A	TUBA1B	0.967
TUBB2A	TUBA1A	0.966		structurally_consistent (dimer)
MADD	TUBB2A	0.966	0.116
TUBB6	TTC5	0.966	0.198
TUBB8	TUBB3	0.965	0.304
TUBA1A	TUBA1C	0.965
MADD	TUBB8	0.958	0.246
RPS27	TUBA1A	0.957
FAS	TBCD	0.956	0.149666666667
CAPS	TUBB6	0.956	0.3
EML6	TUBB2B	0.953
CAPS	TUBB	0.952	0.306608695652
TUBAL3	TUBA1C	0.95	0.97
TUBA1C	TUBB2B	0.95	0.55
DNAJA1	TUBB8	0.95	0.30875
TUBB3	FAS	0.948	0.22
TUBB4A	FAS	0.947	0.164609230769	structurally_consistent (dimer)
RPS27	TUBB8	0.947	0.368	structurally_consistent (dimer)
TUBB2A	CAPS	0.947	0.138	structurally_consistent (dimer)
TUBB2A	TUBB2B	0.94	0.47	structurally_consistent (dimer)
TCP11L1	TUBB6	0.938	0.152
RPS27	CAD	0.934	0.162
ARL2	TTC5	0.934	0.064
TUBB3	TUBB4A	0.933	0.454	structurally_consistent (dimer)
TCP11L1	ARL2	0.932	0.052
TUBB8	TBCD	0.927	0.31
TUBA1A	TTC5	0.92
ARL2	TUBB4A	0.919	0.188
TCP11L1	TUBA1A	0.916
TUBB3	CAPS	0.915	0.142
TUBB6	TCP11L2	0.913		structurally_consistent (P68366)
TUBA1C	TTC5	0.913	0.236
TUBA1A	TUBAL3	0.908
ARL2	FAS	0.906	0.166
TUBB3	TUBA1B	0.9		structurally_consistent (dimer)
TTC5	FAS	0.899	0.11
TUBB	TUBB2B	0.895	0.719
MADD	TUBB3	0.893	0.064
ARL2	TUBB8	0.888	0.362	structurally_consistent (dimer)
DNAJA1	TUBA1C	0.883	0.406
TCP11L2	TTC5	0.878		structurally_consistent (P68366)
TUBB	TCP11L2	0.873
DNAJA1	TUBB6	0.867	0.298
DNAJA1	TUBB4A	0.866	0.22
TUBB2A	TUBA1B	0.864
MADD	TUBB4A	0.864	0.142
TUBB8	CAPS	0.859	0.174
TUBB8	TUBA1C	0.853	0.398
MADD	TUBA1C	0.839	0.254
DNAJA1	RPS27	0.823	0.238	structurally_consistent (P68366)
CAPS	TUBB4A	0.812	0.18
MADD	TUBB	0.811	0.263846153846
TUBA1A	TUBB6	0.805
MADD	TUBA1A	0.798
TCP11L1	TBCD	0.792	0.048	structurally_consistent (Q9BVA1)
TUBB3	TTC5	0.775	0.170162601626
TCP11L1	TUBB8	0.764	0.184
TUBB8	TTC5	0.759	0.172	mutually_exclusive (Q13885)
TUBB3	TBCD	0.752	0.13	structurally_consistent (Q9BVA1)
ARL2	TUBB3	0.742	0.343173015
TUBA1B	CAD	0.74
TTC5	TBCD	0.739	0.036
MADD	FAS	0.725	0.038
TUBB2A	DNAJA1	0.722	0.16
ARL2	TUBB6	0.716	0.1803
CAPS	TUBAL3	0.709	0.228
TUBA1A	CAD	0.692
MADD	TCP11L1	0.655	0.066
MADD	TUBB6	0.633	0.198
RPS27	TUBA1B	0.628
RPS27	TUBB3	0.619	0.258
TUBB4A	TTC5	0.614	0.312888888889
TCP11L1	FAS	0.604	0.112
TCP11L1	TCP11L2	0.602
TUBB8	EML6	0.599
MADD	TBCD	0.592	0.062
TUBB2A	CAD	0.591	0.314
TUBB2A	RPS27	0.587	0.17
RPS27	TUBB2B	0.584	0.358	structurally_consistent (Q3ZCM7)
TCP11L1	TUBAL3	0.559	0.182
CAD	TUBAL3	0.514	0.322
TCP11L1	DNAJA1	0.51	0.084
DNAJA1	CAD	0.506	0.23
RPS27	TBCD	0.5	0.282
TUBB8	CAD	0.494	0.222
TUBB3	TCP11L2	0.478		structurally_consistent (P68366)
TUBB8	TUBA1B	0.467
TUBAL3	TTC5	0.461	0.3525
CAD	TUBB2B	0.445	0.324
MADD	TTC5	0.443	0.098
DNAJA1	TUBB2B	0.435	0.302
TUBA1B	TUBB4A	0.432
TUBA1A	CAPS	0.429
TUBA1A	TUBB2B	0.415
CAD	TCP11L2	0.412
TCP11L1	CAD	0.395	0.058
MADD	TUBB2B	0.389	0.206
EML6	CAPS	0.378
TUBA1B	TUBAL3	0.378		structurally_consistent (dimer)
CAD	TUBB4A	0.353	0.294
MADD	CAD	0.334	0.12
EML6	TUBB6	0.307
ARL2	CAPS	0.303	0.062
ARL2	EML6	0.3
TUBA1B	TBCD	0.288
MADD	DNAJA1	0.281	0.076
CAPS	TUBA1C	0.269	0.342
TUBB3	TUBAL3	0.267	0.432	structurally_consistent (dimer)
MADD	ARL2	0.255	0.114
TUBB	TUBAL3	0.252	0.99
DNAJA1	TUBAL3	0.249	0.306
TUBB6	TBCD	0.243	0.252
RPS27	TUBAL3	0.241	0.27
TUBA1A	TBCD	0.226
DNAJA1	TCP11L2	0.203
MADD	RPS27	0.201	0.138
EML6	TBCD	0.195
TCP11L1	EML6	0.182
EML6	FAS	0.176
CAPS	TBCD	0.169	0.118
ARL2	TUBA1A	0.167
EML6	TTC5	0.157
DNAJA1	TTC5	0.154	0.128
TUBB8	FAS	0.144	0.19
CAPS	TTC5	0.137	0.072
TUBAL3	TUBB2B	0.131	0.400142857143
EML6	TUBB	0.129
TCP11L1	CAPS	0.127	0.1
RPS27	TTC5	0.127	0.21
TUBA1B	TUBB2B	0.12
MADD	TUBAL3	0.114	0.16
TUBA1A	FAS	0.113
TUBB6	CAD	0.102	0.272
TUBAL3	TBCD	0.098	0.242
TUBA1C	TBCD	0.096	0.43
RPS27	TCP11L2	0.095		structurally_consistent (P68366)
ARL2	RPS27	0.089	0.144	structurally_consistent (Q3ZCM7)
DNAJA1	FAS	0.084	0.12
RPS27	FAS	0.083	0.202
TCP11L2	TUBB2B	0.082
EML6	TUBB4A	0.079
ARL2	DNAJA1	0.079	0.094
TUBAL3	FAS	0.077	0.1988
TUBB2A	EML6	0.075
TUBAL3	TUBB4A	0.071	0.784
CAPS	FAS	0.066	0.048	structurally_consistent (Q13885)
EML6	TUBA1A	0.059
TCP11L1	RPS27	0.052	0.078	structurally_consistent (P68366)
DNAJA1	TBCD	0.051	0.226
TUBB2A	TCP11L2	0.051
TCP11L2	TUBB4A	0.051
CAD	TBCD	0.05	0.418
TUBB8	TUBAL3	0.049	0.564
CAD	TTC5	0.044	0.1
EML6	TUBA1C	0.044
TUBB2A	TUBAL3	0.043	0.67
TUBB6	TUBAL3	0.041	0.948
DNAJA1	EML6	0.031
TUBA1B	TTC5	0.029
TUBB8	TCP11L2	0.028
TUBA1B	FAS	0.027
EML6	TUBA1B	0.026
MADD	CAPS	0.023	0.066
TCP11L2	FAS	0.022
TUBA1C	FAS	0.02	0.184
DNAJA1	CAPS	0.019	0.14
EML6	TUBAL3	0.016
ARL2	CAD	0.016	0.07
MADD	TCP11L2	0.015
TCP11L1	TUBA1B	0.015
ARL2	TUBAL3	0.014	0.174
RPS27	CAPS	0.013	0.148
RPS27	EML6	0.011
CAD	FAS	0.01	0.086
TUBA1B	CAPS	0.009
MADD	EML6	0.008
MADD	TUBA1B	0.008
EML6	CAD	0.007
CAPS	CAD	0.005	0.1
ARL2	TUBA1C	0.003	0.208346153846
ARL2	TUBA1B	0.001

Related Complexes

Genename	Complexes
TUBB8	huMAP3_01878.1 huMAP3_06977.1 huMAP3_07762.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_12871.1
DNAJA1	huMAP3_01335.1 huMAP3_02724.1 huMAP3_03106.1 huMAP3_04859.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10363.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_11156.1
TUBB	huMAP3_03106.1 huMAP3_04859.1 huMAP3_06977.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1
CAD	huMAP3_03106.1 huMAP3_04859.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10103.1 huMAP3_10475.1 huMAP3_10665.1
EML6	huMAP3_02722.1 huMAP3_08179.1 huMAP3_08402.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_14043.1 huMAP3_14311.1 huMAP3_14884.1
RPS27	huMAP3_01409.1 huMAP3_01838.1 huMAP3_03106.1 huMAP3_04859.1 huMAP3_07544.1 huMAP3_07864.1 huMAP3_08023.1 huMAP3_08179.1 huMAP3_08373.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_11115.1 huMAP3_12301.1 huMAP3_12727.1
TCP11L2	huMAP3_03385.1 huMAP3_04456.1 huMAP3_04912.1 huMAP3_06491.1 huMAP3_08095.1 huMAP3_08574.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09618.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_11156.1 huMAP3_14584.1
TUBB2B	huMAP3_06977.1 huMAP3_08179.1 huMAP3_08402.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_14311.1
TTC5	huMAP3_06977.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_14311.1 huMAP3_14884.1
TUBAL3	huMAP3_03385.1 huMAP3_04912.1 huMAP3_06491.1 huMAP3_08574.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_10475.1 huMAP3_11156.1 huMAP3_14584.1
TUBB4A	huMAP3_05787.1 huMAP3_06500.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1
TUBA1A	huMAP3_02724.1 huMAP3_05787.1 huMAP3_06977.1 huMAP3_07544.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_11156.1
TUBA4B	huMAP3_03106.1 huMAP3_04859.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1
TUBA1B	huMAP3_02724.1 huMAP3_03810.1 huMAP3_06559.1 huMAP3_07544.1 huMAP3_07864.1 huMAP3_07938.1 huMAP3_08094.1 huMAP3_08179.1 huMAP3_09191.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10656.1 huMAP3_10665.1 huMAP3_11156.1 huMAP3_14584.1
TUBB6	huMAP3_03106.1 huMAP3_04859.1 huMAP3_06977.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_14311.1
MADD	huMAP3_00118.1 huMAP3_00962.1 huMAP3_05951.1 huMAP3_07544.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_10475.1 huMAP3_11346.1
TUBB2A	huMAP3_00118.1 huMAP3_05787.1 huMAP3_06977.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_14311.1
TUBB3	huMAP3_02722.1 huMAP3_06977.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1
TBCD	huMAP3_06977.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_14311.1
CAPS	huMAP3_03106.1 huMAP3_03532.1 huMAP3_04859.1 huMAP3_06197.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_11669.1 huMAP3_12525.1 huMAP3_13292.1 huMAP3_14468.1 huMAP3_14491.1 huMAP3_14682.1
TUBA1C	huMAP3_03385.1 huMAP3_04456.1 huMAP3_04912.1 huMAP3_05787.1 huMAP3_06977.1 huMAP3_08094.1 huMAP3_08574.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_11156.1
ARL2	huMAP3_01239.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10142.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_13133.1 huMAP3_14311.1 huMAP3_14884.1
FAS	huMAP3_06977.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_12841.1 huMAP3_14311.1
TCP11L1	huMAP3_00374.1 huMAP3_05787.1 huMAP3_06064.1 huMAP3_07544.1 huMAP3_07625.1 huMAP3_07762.1 huMAP3_08179.1 huMAP3_08262.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10547.1 huMAP3_10665.1 huMAP3_11283.1 huMAP3_14236.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_09603.1

Complex Portal: CPX-24181