hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09625.1
Confidence: Moderate High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
TTC23 | Tetratricopeptide repeat protein 23 (TPR repeat protein 23) (Cervical cancer proto-oncogene 8 protein) (HCC-8) | 5 | UniProt   NCBI |
RFFL | E3 ubiquitin-protein ligase rififylin (EC 2.3.2.27) (Caspase regulator CARP2) (Caspases-8 and -10-associated RING finger protein 2) (CARP-2) (FYVE-RING finger protein Sakura) (Fring) (RING finger and FYVE-like domain-containing protein 1) (RING finger protein 189) (RING finger protein 34-like) (RING-type E3 ubiquitin transferase rififylin) | 5 | UniProt   NCBI |
TTC23L | Tetratricopeptide repeat protein 23-like | 5 | UniProt   NCBI |
IQCE | IQ domain-containing protein E | 5 | UniProt   NCBI |
EFCAB7 | EF-hand calcium-binding domain-containing protein 7 | 4 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  WP:WP4536 | 0.000181875223355 | 0.6 | TTC23 EFCAB7 IQCE | Genes related to primary cilium development based on CRISPR |
  REAC:R-HSA-5635838 | 0.0011839189519 | 0.4 | IQCE EFCAB7 | Activation of SMO |
  KEGG:04340 | 0.00447375439216 | 0.4 | IQCE EFCAB7 | Hedgehog signaling pathway |
  REAC:R-HSA-5632684 | 0.0440242300692 | 0.4 | IQCE EFCAB7 | Hedgehog 'on' state |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 TTC23L |  IQCE | 0.999 |            | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
 RFFL |  IQCE | 0.999 |            | bioplex3_HEK293     bioplex ()     bioplex3_WMM     bioplex3_HCT116     |
 EFCAB7 |  TTC23L | 0.999 |            | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
 TTC23 |  IQCE | 0.997 |            | bioplex3_WMM     bioplex3_HCT116     WMM_only     |
 EFCAB7 |  TTC23 | 0.991 |            | bioplex3_WMM     bioplex3_HCT116     WMM_only     |
 EFCAB7 |  IQCE | 0.972 |            | bioplex_WMM     bioplex3_WMM     WMM_only     |
 EFCAB7 |  RFFL | 0.78 |            | bioplex3_HEK293     bioplex ()     bioplex3_WMM     |
Related Complexes