hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_09634.1

Complex Portal: CPX-20617

Confidence: Moderate High

Genename	Protein Name	Uniprot Annotation Score	Links
GLCCI1	Glucocorticoid-induced transcript 1 protein	2	UniProt NCBI
DYNLL2	Dynein light chain 2, cytoplasmic (8 kDa dynein light chain b) (DLC8b) (Dynein light chain LC8-type 2)	5	UniProt NCBI
KANK1	KN motif and ankyrin repeat domain-containing protein 1 (Ankyrin repeat domain-containing protein 15) (Kidney ankyrin repeat-containing protein)	5	UniProt NCBI
DYNLL1	Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)	5	UniProt NCBI
DYNC1I1	Cytoplasmic dynein 1 intermediate chain 1 (Cytoplasmic dynein intermediate chain 1) (Dynein intermediate chain 1, cytosolic) (DH IC-1)	5	UniProt NCBI
FAM117B	Protein FAM117B (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 13 protein)	5	UniProt NCBI
FAM83D	Protein FAM83D (Spindle protein CHICA)	5	UniProt NCBI
SECISBP2L	Selenocysteine insertion sequence-binding protein 2-like (SECIS-binding protein 2-like)	4	UniProt NCBI
ZNF710	Zinc finger protein 710	3	UniProt NCBI
HMMR	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid-binding protein) (Receptor for hyaluronan-mediated motility) (CD antigen CD168)	5	UniProt NCBI
MORC3	MORC family CW-type zinc finger protein 3 (Nuclear matrix protein 2) (Zinc finger CW-type coiled-coil domain protein 3)	5	UniProt NCBI
ZNF608	Zinc finger protein 608 (Renal carcinoma antigen NY-REN-36)	3	UniProt NCBI
DYNLRB1	Dynein light chain roadblock-type 1 (Bithoraxoid-like protein) (BLP) (Dynein light chain 2A, cytoplasmic) (Dynein-associated protein Km23) (Roadblock domain-containing protein 1)	5	UniProt NCBI
DYNLT3	Dynein light chain Tctex-type 3 (Protein 91/23) (T-complex-associated testis-expressed 1-like)	5	UniProt NCBI
BLTP3B	Bridge-like lipid transfer protein family member 3B (Syntaxin-6 Habc-interacting protein of 164 kDa) (UHRF1-binding protein 1-like)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
WP:WP4532	4.79047295891e-09	0.333333333333	DYNLRB1 DYNLL1 DYNLT3 DYNLL2 DYNC1I1	Intraflagellar transport proteins binding to dynein
CORUM:6236	1.71779558077e-08	0.266666666667	DYNLT3 DYNLL1 DYNLL2 DYNLRB1	Dynein-2 complex, cytoplasmic
GO:0005868	5.45238993503e-07	0.333333333333	DYNLRB1 DYNLL1 DYNLT3 DYNLL2 DYNC1I1	cytoplasmic dynein complex
GO:0030286	6.31584282351e-06	0.333333333333	DYNLRB1 DYNLL1 DYNLT3 DYNLL2 DYNC1I1	dynein complex
KEGG:04814	2.46214106647e-05	0.333333333333	DYNLRB1 DYNLL1 DYNLT3 DYNLL2 DYNC1I1	Motor proteins
WP:WP4906	3.05361062072e-05	0.266666666667	DYNLT3 DYNLL1 DYNLL2 DYNLRB1	3q29 copy number variation syndrome
GO:0045505	3.57366752742e-05	0.266666666667	DYNLT3 DYNLL1 DYNLL2 DYNLRB1	dynein intermediate chain binding
KEGG:05132	0.000122189492822	0.333333333333	DYNLRB1 DYNLL1 DYNLT3 DYNLL2 DYNC1I1	Salmonella infection
CORUM:6038	0.000286035615974	0.133333333333	DYNLL1 DYNC1I1	Dynein complex
CORUM:6039	0.000476443303259	0.133333333333	DYNLL1 DYNC1I1	Dynein-dynactin complex
KEGG:04962	0.000481592689177	0.2	DYNLL1 DYNLL2 DYNC1I1	Vasopressin-regulated water reabsorption
WP:WP5085	0.000938570640907	0.2	DYNLL1 DYNLL2 DYNC1I1	Vasopressin regulated water reabsorption
REAC:R-HSA-9646399	0.00272706541831	0.2	DYNLL1 DYNLL2 DYNC1I1	Aggrephagy
REAC:R-HSA-6811436	0.00498637410589	0.2	DYNLL1 DYNLL2 DYNC1I1	COPI-independent Golgi-to-ER retrograde traffic
REAC:R-HSA-5620924	0.00529475720887	0.2	DYNLL1 DYNLL2 DYNLRB1	Intraflagellar transport
WP:WP4352	0.00544639685614	0.266666666667	DYNLT3 DYNLL1 DYNLL2 DYNLRB1	Ciliary landscape
GO:0005875	0.00546129601899	0.333333333333	DYNLRB1 DYNLL1 DYNLT3 DYNLL2 DYNC1I1	microtubule associated complex
REAC:R-HSA-3371497	0.00561546291409	0.2	DYNLL1 DYNLL2 DYNC1I1	HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
REAC:R-HSA-9663891	0.0169160381413	0.2	DYNLL1 DYNLL2 DYNC1I1	Selective autophagy
REAC:R-HSA-141424	0.0311315607877	0.2	DYNLL1 DYNLL2 DYNC1I1	Amplification of signal from the kinetochores
REAC:R-HSA-141444	0.0311315607877	0.2	DYNLL1 DYNLL2 DYNC1I1	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
REAC:R-HSA-6807878	0.0353329800227	0.2	DYNLL1 DYNLL2 DYNC1I1	COPI-mediated anterograde transport

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
FAM83D	HMMR	1.0	0.166
DYNC1I1	DYNLRB1	0.999	0.262	structurally_consistent (dimer)
DYNC1I1	DYNLT3	0.999	0.144
GLCCI1	DYNLL1	0.998	0.226	mutually_exclusive (Q96FJ2) structurally_consistent (dimer)
DYNC1I1	DYNLL1	0.997	0.214	mutually_exclusive (Q96FJ2) structurally_consistent (dimer)
DYNLL1	MORC3	0.995	0.222
DYNC1I1	DYNLL2	0.995	0.136	mutually_exclusive (P63167) structurally_consistent (dimer)
GLCCI1	FAM117B	0.994	0.082
DYNLL1	FAM117B	0.993	0.19
GLCCI1	SECISBP2L	0.991	0.134
DYNLL2	DYNLL1	0.99	0.214	structurally_consistent (dimer)
DYNLT3	DYNLRB1	0.989	0.156
FAM83D	DYNC1I1	0.988	0.086
FAM83D	DYNLL1	0.988	0.176
DYNLL1	KANK1	0.983	0.176
FAM83D	FAM117B	0.982	0.044
GLCCI1	KANK1	0.982	0.036
DYNLL2	FAM117B	0.981	0.1
DYNLL1	BLTP3B	0.98	0.156
DYNLL2	MORC3	0.979	0.088
FAM83D	SECISBP2L	0.968	0.072
FAM83D	DYNLL2	0.966	0.07
FAM117B	BLTP3B	0.965	0.078
GLCCI1	HMMR	0.965	0.084
FAM83D	GLCCI1	0.96	0.064
DYNLL1	ZNF710	0.959
DYNLL1	ZNF608	0.954	0.342
DYNLL1	DYNLRB1	0.953	0.188
HMMR	SECISBP2L	0.952	0.074
FAM117B	KANK1	0.952	0.046
GLCCI1	BLTP3B	0.949	0.06
DYNLL2	KANK1	0.949	0.133162162162
SECISBP2L	DYNLRB1	0.948	0.1
SECISBP2L	BLTP3B	0.939	0.096
GLCCI1	DYNLL2	0.936	0.13	mutually_exclusive (P63167) structurally_consistent (dimer)
HMMR	KANK1	0.932	0.092
SECISBP2L	DYNLL1	0.93	0.124
FAM83D	KANK1	0.924	0.196
DYNLL2	BLTP3B	0.923	0.08
SECISBP2L	KANK1	0.919	0.086
KANK1	BLTP3B	0.918	0.088
SECISBP2L	DYNLL2	0.909	0.13
FAM117B	DYNLRB1	0.907	0.088
GLCCI1	DYNLRB1	0.899	0.08
DYNLL2	ZNF608	0.897	0.142
HMMR	FAM117B	0.893	0.03
DYNLL2	ZNF710	0.89
SECISBP2L	FAM117B	0.884	0.114
DYNLT3	DYNLL1	0.879	0.302
HMMR	DYNLL1	0.857	0.09
DYNLT3	DYNLL2	0.839	0.108	mutually_exclusive (Q8WW35)
DYNLL2	DYNLRB1	0.674	0.054
HMMR	DYNLL2	0.49	0.082
FAM83D	DYNLRB1	0.451	0.0886666666667
FAM83D	DYNLT3	0.426	0.028
HMMR	BLTP3B	0.422	0.108
FAM83D	BLTP3B	0.42	0.108
ZNF710	ZNF608	0.391
KANK1	DYNLRB1	0.381	0.08
DYNC1I1	ZNF710	0.287
MORC3	FAM117B	0.269	0.048
FAM83D	MORC3	0.238	0.03
MORC3	BLTP3B	0.169	0.092
HMMR	DYNLRB1	0.169	0.02
SECISBP2L	MORC3	0.157	0.094
GLCCI1	MORC3	0.157	0.03
HMMR	MORC3	0.157	0.044
ZNF710	MORC3	0.135
DYNC1I1	ZNF608	0.123	0.106
MORC3	ZNF608	0.114	0.152
BLTP3B	DYNLRB1	0.097	0.048
ZNF608	DYNLRB1	0.095	0.084
ZNF710	DYNLRB1	0.095
MORC3	DYNLRB1	0.095	0.046
FAM83D	ZNF608	0.095	0.086
DYNC1I1	KANK1	0.079	0.08
ZNF710	BLTP3B	0.079
DYNC1I1	BLTP3B	0.079	0.062
HMMR	ZNF710	0.079
MORC3	KANK1	0.079	0.05
GLCCI1	ZNF710	0.079
DYNC1I1	HMMR	0.079	0.13
DYNC1I1	MORC3	0.079	0.116
ZNF608	KANK1	0.079	0.092
DYNC1I1	GLCCI1	0.079	0.072
FAM83D	ZNF710	0.079
HMMR	ZNF608	0.079	0.132
GLCCI1	ZNF608	0.079	0.09
ZNF608	BLTP3B	0.079	0.12
DYNC1I1	FAM117B	0.079	0.078
ZNF710	KANK1	0.079
ZNF608	FAM117B	0.079	0.106
ZNF710	FAM117B	0.079
DYNC1I1	SECISBP2L	0.079	0.104
SECISBP2L	ZNF710	0.079
SECISBP2L	ZNF608	0.073	0.104

Related Complexes

Genename	Complexes
GLCCI1	huMAP3_02248.1 huMAP3_04345.1 huMAP3_05467.1 huMAP3_06995.1 huMAP3_07813.1 huMAP3_08770.1 huMAP3_09634.1 huMAP3_10849.1 huMAP3_10951.1 huMAP3_12566.1
DYNLL2	huMAP3_04180.1 huMAP3_06765.1 huMAP3_07734.1 huMAP3_08990.1 huMAP3_09634.1 huMAP3_09802.1 huMAP3_10156.1 huMAP3_12566.1 huMAP3_15289.1
KANK1	huMAP3_05467.1 huMAP3_06995.1 huMAP3_08142.1 huMAP3_08536.1 huMAP3_08990.1 huMAP3_09447.1 huMAP3_09634.1 huMAP3_12566.1
DYNLL1	huMAP3_04180.1 huMAP3_06765.1 huMAP3_07734.1 huMAP3_08536.1 huMAP3_08990.1 huMAP3_09634.1 huMAP3_09802.1 huMAP3_10156.1 huMAP3_12566.1 huMAP3_15289.1
DYNC1I1	huMAP3_02226.1 huMAP3_07382.1 huMAP3_07734.1 huMAP3_08990.1 huMAP3_09593.1 huMAP3_09634.1 huMAP3_09802.1 huMAP3_11519.1 huMAP3_12566.1 huMAP3_15007.1 huMAP3_15289.1
FAM117B	huMAP3_04345.1 huMAP3_05467.1 huMAP3_06995.1 huMAP3_08536.1 huMAP3_08990.1 huMAP3_09634.1 huMAP3_10849.1 huMAP3_12566.1
FAM83D	huMAP3_00063.1 huMAP3_02248.1 huMAP3_05467.1 huMAP3_05910.1 huMAP3_07813.1 huMAP3_08770.1 huMAP3_09634.1 huMAP3_10849.1 huMAP3_10951.1 huMAP3_12566.1
SECISBP2L	huMAP3_02248.1 huMAP3_03260.1 huMAP3_04345.1 huMAP3_05467.1 huMAP3_07813.1 huMAP3_08770.1 huMAP3_09634.1 huMAP3_10849.1 huMAP3_10951.1 huMAP3_11080.1 huMAP3_12566.1
ZNF710	huMAP3_04180.1 huMAP3_06765.1 huMAP3_07734.1 huMAP3_08536.1 huMAP3_08990.1 huMAP3_09634.1 huMAP3_09802.1 huMAP3_10156.1 huMAP3_12566.1 huMAP3_15289.1
HMMR	huMAP3_02248.1 huMAP3_05467.1 huMAP3_07813.1 huMAP3_09634.1 huMAP3_10849.1 huMAP3_10951.1 huMAP3_12566.1 huMAP3_13906.1
MORC3	huMAP3_04180.1 huMAP3_06765.1 huMAP3_07734.1 huMAP3_08990.1 huMAP3_09634.1 huMAP3_09802.1 huMAP3_10156.1 huMAP3_12159.1
ZNF608	huMAP3_04180.1 huMAP3_06765.1 huMAP3_07734.1 huMAP3_08536.1 huMAP3_08990.1 huMAP3_09634.1 huMAP3_09802.1 huMAP3_10156.1 huMAP3_12566.1 huMAP3_15289.1
DYNLRB1	huMAP3_07382.1 huMAP3_08809.1 huMAP3_08818.1 huMAP3_09593.1 huMAP3_09634.1 huMAP3_09802.1 huMAP3_11519.1 huMAP3_12566.1 huMAP3_15007.1 huMAP3_15289.1
DYNLT3	huMAP3_02226.1 huMAP3_07382.1 huMAP3_08809.1 huMAP3_08818.1 huMAP3_09593.1 huMAP3_09634.1 huMAP3_09802.1 huMAP3_11519.1 huMAP3_12566.1 huMAP3_15007.1 huMAP3_15289.1
BLTP3B	huMAP3_07347.1 huMAP3_08536.1 huMAP3_08990.1 huMAP3_09104.1 huMAP3_09634.1 huMAP3_12566.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_09634.1

Complex Portal: CPX-20617