hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09635.1
Complex Portal: CPX-23106
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IGFBP4 | Insulin-like growth factor-binding protein 4 (IBP-4) (IGF-binding protein 4) (IGFBP-4) | 5 | UniProt NCBI |
| IL25 | Interleukin-25 (IL-25) (Interleukin-17E) (IL-17E) | 5 | UniProt NCBI |
| INHBE | Inhibin beta E chain (Activin beta-E chain) | 4 | UniProt NCBI |
| HEY1 | Hairy/enhancer-of-split related with YRPW motif protein 1 (Cardiovascular helix-loop-helix factor 2) (CHF-2) (Class B basic helix-loop-helix protein 31) (bHLHb31) (HES-related repressor protein 1) (Hairy and enhancer of split-related protein 1) (HESR-1) (Hairy-related transcription factor 1) (HRT-1) (hHRT1) | 5 | UniProt NCBI |
| NMNAT2 | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 (NMN/NaMN adenylyltransferase 2) (EC 2.7.7.1) (EC 2.7.7.18) (Nicotinamide mononucleotide adenylyltransferase 2) (NMN adenylyltransferase 2) (Nicotinate-nucleotide adenylyltransferase 2) (NaMN adenylyltransferase 2) | 5 | UniProt NCBI |
| MYCBP2 | E3 ubiquitin-protein ligase MYCBP2 (EC 2.3.2.33) (Myc-binding protein 2) (Protein associated with Myc) | 5 | UniProt NCBI |
| FBXO45 | F-box/SPRY domain-containing protein 1 (F-box only protein 45) (hFbxo45) | 5 | UniProt NCBI |
| SPRYD3 | SPRY domain-containing protein 3 | 2 | UniProt NCBI |
| CS | Citrate synthase, mitochondrial (EC 2.3.3.1) (Citrate (Si)-synthase) | 5 | UniProt NCBI |
| PCDH10 | Protocadherin-10 | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4906 | 0.0482342246392 | 0.222222222222 | MYCBP2 FBXO45 | 3q29 copy number variation syndrome |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| FBXO45 | CS | 0.997 | 0.154 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| INHBE | FBXO45 | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| FBXO45 | MYCBP2 | 0.995 | 0.1 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| CS | MYCBP2 | 0.993 | 0.108 | hein_WMM bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM WMM_only | |
| FBXO45 | SPRYD3 | 0.992 | 0.124 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt_WMM WMM_only | |
| SPRYD3 | MYCBP2 | 0.989 | 0.146 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | |
| HEY1 | CS | 0.989 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| IL25 | FBXO45 | 0.987 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| IL25 | SPRYD3 | 0.985 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PCDH10 | MYCBP2 | 0.985 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| HEY1 | FBXO45 | 0.984 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| NMNAT2 | FBXO45 | 0.981 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| IGFBP4 | SPRYD3 | 0.98 | 0.05 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| HEY1 | MYCBP2 | 0.975 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| HEY1 | SPRYD3 | 0.971 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| IGFBP4 | FBXO45 | 0.97 | 0.086 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| NMNAT2 | SPRYD3 | 0.966 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| SPRYD3 | CS | 0.959 | 0.148 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| IL25 | MYCBP2 | 0.957 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| INHBE | SPRYD3 | 0.953 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| INHBE | CS | 0.935 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| IGFBP4 | CS | 0.89 | 0.07 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| INHBE | MYCBP2 | 0.84 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| IGFBP4 | MYCBP2 | 0.764 | 0.216 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDH10 | FBXO45 | 0.726 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| NMNAT2 | MYCBP2 | 0.668 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PCDH10 | HEY1 | 0.2 | bioplex3_WMM WMM_only | ||
| PCDH10 | CS | 0.162 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PCDH10 | SPRYD3 | 0.081 | bioplex3_WMM WMM_only | ||
| NMNAT2 | CS | 0.02 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| IL25 | CS | 0.018 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes