hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_09654.1

Complex Portal: CPX-16594

Confidence: Moderate High

Genename	Protein Name	Uniprot Annotation Score	Links
APOBEC3B	DNA dC->dU-editing enzyme APOBEC-3B (A3B) (EC 3.5.4.38) (Phorbolin-1-related protein) (Phorbolin-2/3)	5	UniProt NCBI
RALY	RNA-binding protein Raly (Autoantigen p542) (Heterogeneous nuclear ribonucleoprotein C-like 2) (hnRNP core protein C-like 2) (hnRNP associated with lethal yellow protein homolog)	5	UniProt NCBI
ZNF326	DBIRD complex subunit ZNF326 (Zinc finger protein 326) (Zinc finger protein interacting with mRNPs and DBC1)	5	UniProt NCBI
HNRNPA0	Heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0)	5	UniProt NCBI
HNRNPD	Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1)	5	UniProt NCBI
HNRNPH3	Heterogeneous nuclear ribonucleoprotein H3 (hnRNP H3) (Heterogeneous nuclear ribonucleoprotein 2H9) (hnRNP 2H9)	5	UniProt NCBI
HNRNPAB	Heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) (APOBEC1-binding protein 1) (ABBP-1)	5	UniProt NCBI
TNK1	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)	5	UniProt NCBI
FAM120A	Constitutive coactivator of PPAR-gamma-like protein 1 (Oxidative stress-associated SRC activator) (Protein FAM120A)	5	UniProt NCBI
HNRNPA3	Heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3)	5	UniProt NCBI
HNRNPL	Heterogeneous nuclear ribonucleoprotein L (hnRNP L)	5	UniProt NCBI
RBMX	RNA-binding motif protein, X chromosome (Glycoprotein p43) (Heterogeneous nuclear ribonucleoprotein G) (hnRNP G) [Cleaved into: RNA-binding motif protein, X chromosome, N-terminally processed]	5	UniProt NCBI
HNRNPR	Heterogeneous nuclear ribonucleoprotein R (hnRNP R)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0003723	3.29371301519e-06	0.916666666667	FAM120A ZNF326 HNRNPR RALY HNRNPA0 HNRNPH3 HNRNPAB APOBEC3B RBMX HNRNPD HNRNPA3	RNA binding
CORUM:1181	2.07670268871e-05	0.333333333333	RALY HNRNPA3 HNRNPR RBMX	C complex spliceosome
GO:0016071	8.77764780154e-05	0.666666666667	HNRNPR RALY HNRNPA0 HNRNPH3 HNRNPAB RBMX HNRNPD HNRNPA3	mRNA metabolic process
WP:WP411	0.00025379591153	0.333333333333	HNRNPD RBMX HNRNPR HNRNPAB	mRNA processing
HPA:0080133	0.000639282645839	0.583333333333	FAM120A HNRNPR RALY RBMX HNRNPA0 HNRNPAB HNRNPD	caudate; neuronal cells[High]
HPA:0570783	0.000779107698083	0.5	RALY RBMX HNRNPA0 HNRNPR HNRNPD HNRNPA3	testis; preleptotene spermatocytes[High]
HPA:0090183	0.0010125175611	0.5	HNRNPR RALY RBMX HNRNPAB HNRNPD HNRNPA3	cerebellum; cells in granular layer[High]
GO:0006396	0.00113865950967	0.666666666667	ZNF326 RALY HNRNPH3 HNRNPA0 HNRNPR RBMX HNRNPD HNRNPA3	RNA processing
GO:0097159	0.00130047744368	1.0	FAM120A ZNF326 HNRNPR RALY TNK1 HNRNPA0 HNRNPH3 HNRNPAB APOBEC3B RBMX HNRNPD HNRNPA3	organic cyclic compound binding
HPA:0100133	0.00138981138256	0.666666666667	FAM120A HNRNPR RALY HNRNPA0 RBMX HNRNPAB HNRNPD HNRNPA3	cerebral cortex; neuronal cells[High]
HPA:0461492	0.00153503865516	0.333333333333	RALY HNRNPA0 HNRNPR HNRNPA3	skin 1; vascular mural cells[>=Medium]
HPA:0090193	0.00313165097646	0.5	HNRNPR RALY RBMX HNRNPAB HNRNPD HNRNPA3	cerebellum; cells in molecular layer[High]
HPA:0461491	0.00406113347236	0.333333333333	RALY HNRNPA0 HNRNPR HNRNPA3	skin 1; vascular mural cells[>=Low]
REAC:R-HSA-72163	0.00428408810581	0.333333333333	HNRNPD HNRNPA3 HNRNPR RBMX	mRNA Splicing - Major Pathway
REAC:R-HSA-72172	0.00490260156577	0.333333333333	HNRNPD HNRNPA3 HNRNPR RBMX	mRNA Splicing
GO:0003676	0.00532200603023	0.916666666667	FAM120A ZNF326 HNRNPR RALY HNRNPA0 HNRNPH3 HNRNPAB APOBEC3B RBMX HNRNPD HNRNPA3	nucleic acid binding
GO:0006397	0.00570511239629	0.5	HNRNPH3 RALY RBMX HNRNPA0 HNRNPR HNRNPA3	mRNA processing
GO:1990904	0.00572985936951	0.583333333333	HNRNPR RALY RBMX HNRNPH3 HNRNPAB HNRNPD HNRNPA3	ribonucleoprotein complex
GO:0005681	0.00744285691253	0.416666666667	RALY RBMX HNRNPH3 HNRNPR HNRNPA3	spliceosomal complex
GO:0008380	0.00963205879678	0.5	ZNF326 RALY RBMX HNRNPH3 HNRNPR HNRNPA3	RNA splicing
HPA:0130053	0.0106518239586	0.666666666667	FAM120A ZNF326 HNRNPR RALY RBMX HNRNPAB HNRNPD HNRNPA3	colon; glandular cells[High]
HPA:0471472	0.0112235086656	0.416666666667	HNRNPR RALY HNRNPA0 HNRNPA3 HNRNPD	skin 2; lymphocytes[>=Medium]
HPA:0080123	0.0120331152822	0.416666666667	HNRNPAB RALY HNRNPA3 FAM120A HNRNPD	caudate; glial cells[High]
HPA:0471462	0.0125021051311	0.416666666667	HNRNPR RALY HNRNPA0 HNRNPA3 HNRNPD	skin 2; langerhans cells[>=Medium]
GO:1903312	0.0137538335332	0.333333333333	HNRNPD RBMX HNRNPA0 HNRNPAB	negative regulation of mRNA metabolic process
HPA:0471412	0.0142038377679	0.416666666667	HNRNPR RALY HNRNPA0 HNRNPA3 HNRNPD	skin 2; cells in spinous layer[>=Medium]
HPA:0630053	0.0143530846137	0.5	FAM120A RALY RBMX HNRNPAB HNRNPD HNRNPA3	cervix; glandular cells[High]
REAC:R-HSA-72203	0.0144394333169	0.333333333333	HNRNPD HNRNPA3 HNRNPR RBMX	Processing of Capped Intron-Containing Pre-mRNA
HPA:0480053	0.015405026031	0.666666666667	FAM120A ZNF326 HNRNPR RALY RBMX HNRNPAB HNRNPD HNRNPA3	small intestine; glandular cells[High]
HPA:0400053	0.0169339849648	0.666666666667	FAM120A ZNF326 HNRNPR RALY RBMX HNRNPAB HNRNPD HNRNPA3	rectum; glandular cells[High]
HPA:0460181	0.0171485441646	0.416666666667	HNRNPR RALY HNRNPA0 HNRNPA3 HNRNPD	skin 1; cells in granular layer[>=Low]
HPA:0100123	0.0182710753759	0.416666666667	HNRNPAB RALY HNRNPA3 HNRNPR HNRNPD	cerebral cortex; glial cells[High]
HPA:0461461	0.0193159602137	0.416666666667	HNRNPR RALY HNRNPA0 HNRNPA3 HNRNPD	skin 1; langerhans cells[>=Low]
HPA:0030053	0.019827659868	0.583333333333	FAM120A ZNF326 RALY RBMX HNRNPAB HNRNPD HNRNPA3	appendix; glandular cells[High]
HPA:0100122	0.019829312587	0.666666666667	FAM120A ZNF326 HNRNPR RALY RBMX HNRNPAB HNRNPD HNRNPA3	cerebral cortex; glial cells[>=Medium]
HPA:0461493	0.0210298438139	0.25	RALY HNRNPA3 HNRNPR	skin 1; vascular mural cells[High]
HPA:0461411	0.0254188364135	0.416666666667	HNRNPR RALY HNRNPA0 HNRNPA3 HNRNPD	skin 1; cells in spinous layer[>=Low]
GO:0071013	0.0279547943144	0.333333333333	RALY HNRNPA3 HNRNPR RBMX	catalytic step 2 spliceosome
HPA:0471461	0.0285266659142	0.416666666667	HNRNPR RALY HNRNPA0 HNRNPA3 HNRNPD	skin 2; langerhans cells[>=Low]
HPA:0471471	0.0311404785914	0.416666666667	HNRNPR RALY HNRNPA0 HNRNPA3 HNRNPD	skin 2; lymphocytes[>=Low]
HPA:0270353	0.0333208240154	0.416666666667	HNRNPAB RALY RBMX HNRNPR HNRNPD	kidney; cells in glomeruli[High]
HPA:0570782	0.0342542759389	0.5	RALY RBMX HNRNPA0 HNRNPR HNRNPD HNRNPA3	testis; preleptotene spermatocytes[>=Medium]
HPA:0220053	0.0345068762131	0.666666666667	FAM120A ZNF326 HNRNPR RALY RBMX HNRNPAB HNRNPD HNRNPA3	gallbladder; glandular cells[High]
HPA:0471442	0.0360473774303	0.416666666667	HNRNPR RALY HNRNPA0 HNRNPA3 HNRNPD	skin 2; fibrohistiocytic cells[>=Medium]
REAC:R-HSA-8953854	0.0361764041169	0.416666666667	HNRNPD RBMX APOBEC3B HNRNPR HNRNPA3	Metabolism of RNA
HPA:0090182	0.0377305038296	0.666666666667	FAM120A HNRNPR RALY HNRNPA0 RBMX HNRNPAB HNRNPD HNRNPA3	cerebellum; cells in granular layer[>=Medium]
HPA:0270363	0.0423467545894	0.583333333333	FAM120A ZNF326 HNRNPR RALY RBMX HNRNPAB HNRNPD	kidney; cells in tubules[High]
HPA:0570763	0.0439947055696	0.416666666667	HNRNPR RALY HNRNPA0 HNRNPA3 HNRNPD	testis; pachytene spermatocytes[High]
HPA:0471411	0.0455267055955	0.416666666667	HNRNPR RALY HNRNPA0 HNRNPA3 HNRNPD	skin 2; cells in spinous layer[>=Low]
HPA:0570793	0.0481708555291	0.416666666667	HNRNPR RALY HNRNPA0 HNRNPA3 HNRNPD	testis; round or early spermatids[High]
HPA:0461391	0.0495363976676	0.416666666667	HNRNPR RALY HNRNPA0 HNRNPA3 HNRNPD	skin 1; cells in basal layer[>=Low]
CORUM:7337	0.0499436884912	0.0833333333333	HNRNPD	AUF1(p45)-ZFP36 complex

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
ZNF326	RALY	0.999	0.162	mutually_exclusive (Q12905)
HNRNPA3	RALY	0.998	0.662
RBMX	HNRNPL	0.998	0.908
FAM120A	HNRNPR	0.998
FAM120A	HNRNPL	0.998
HNRNPR	RBMX	0.997	0.854
HNRNPR	HNRNPL	0.997	0.948
HNRNPR	ZNF326	0.997	0.456	mutually_exclusive (Q12905)
RBMX	ZNF326	0.996	0.446
RBMX	RALY	0.996	0.508
ZNF326	APOBEC3B	0.996	0.058
HNRNPR	RALY	0.996	0.476	mutually_exclusive (Q12905)
HNRNPR	APOBEC3B	0.994	0.3735
FAM120A	RALY	0.993
HNRNPD	HNRNPAB	0.993	0.67
HNRNPA3	FAM120A	0.993
FAM120A	ZNF326	0.992
HNRNPA3	HNRNPAB	0.991	0.586
RBMX	APOBEC3B	0.989	0.24
HNRNPA3	HNRNPR	0.989	0.944
HNRNPA3	RBMX	0.988	0.72
HNRNPA3	HNRNPH3	0.988	0.79
HNRNPA3	HNRNPA0	0.987	0.88
FAM120A	HNRNPH3	0.986
FAM120A	HNRNPA0	0.984
HNRNPA3	ZNF326	0.984	0.226
FAM120A	RBMX	0.982
HNRNPA0	HNRNPAB	0.981	0.442
FAM120A	TNK1	0.98
HNRNPR	HNRNPAB	0.98	0.61
HNRNPA0	HNRNPL	0.978	0.836
RALY	HNRNPL	0.976	0.514
HNRNPAB	RALY	0.974	0.368
FAM120A	HNRNPAB	0.974
HNRNPA0	RBMX	0.973	0.776
HNRNPD	HNRNPA3	0.972	0.86
HNRNPA0	RALY	0.971	0.39
HNRNPA3	HNRNPL	0.963	0.852
RALY	APOBEC3B	0.962	0.196
APOBEC3B	HNRNPL	0.959	0.383541666667
HNRNPH3	RALY	0.958	0.41
HNRNPD	HNRNPA0	0.954	0.59
HNRNPAB	HNRNPL	0.952	0.808
FAM120A	APOBEC3B	0.951
HNRNPA0	HNRNPH3	0.951	0.624
HNRNPR	HNRNPA0	0.946	0.938
ZNF326	HNRNPL	0.937	0.658
HNRNPD	FAM120A	0.933
HNRNPA3	APOBEC3B	0.93	0.258
HNRNPAB	ZNF326	0.901	0.374
HNRNPH3	ZNF326	0.888	0.206
HNRNPA0	ZNF326	0.879	0.272
HNRNPH3	RBMX	0.862	0.654
HNRNPH3	HNRNPL	0.861	0.748
HNRNPH3	HNRNPAB	0.858	0.488
HNRNPD	HNRNPR	0.853	0.854
HNRNPD	RBMX	0.848	0.766666666667
HNRNPD	HNRNPL	0.848	0.794
HNRNPH3	APOBEC3B	0.846	0.204
HNRNPD	HNRNPH3	0.796	0.524
ZNF326	TNK1	0.796	0.142
HNRNPA0	APOBEC3B	0.769	0.188
TNK1	APOBEC3B	0.764	0.068
HNRNPH3	TNK1	0.578	0.132
RBMX	TNK1	0.567	0.212
HNRNPR	TNK1	0.54	0.158
HNRNPA3	TNK1	0.525	0.17
HNRNPA0	TNK1	0.518	0.16
HNRNPAB	APOBEC3B	0.482	0.208733944954
HNRNPD	APOBEC3B	0.448	0.288
HNRNPD	RALY	0.389	0.446
HNRNPAB	RBMX	0.325	0.658
HNRNPR	HNRNPH3	0.232	0.712
TNK1	HNRNPL	0.152	0.216
HNRNPD	TNK1	0.113	0.252
HNRNPAB	TNK1	0.08	0.322
TNK1	RALY	0.063	0.163
HNRNPD	ZNF326	0.007	0.288

Related Complexes

Genename	Complexes
APOBEC3B	huMAP3_04752.1 huMAP3_05721.1 huMAP3_06975.1 huMAP3_08180.1 huMAP3_09654.1 huMAP3_10625.1 huMAP3_10659.1 huMAP3_11032.1 huMAP3_11768.1 huMAP3_14523.1
RALY	huMAP3_04705.1 huMAP3_05931.1 huMAP3_06081.1 huMAP3_06093.1 huMAP3_06671.1 huMAP3_07115.1 huMAP3_07225.1 huMAP3_07581.1 huMAP3_08027.1 huMAP3_09223.1 huMAP3_09556.1 huMAP3_09654.1 huMAP3_10625.1 huMAP3_10659.1 huMAP3_11073.1
ZNF326	huMAP3_04113.1 huMAP3_06671.1 huMAP3_07272.1 huMAP3_07400.1 huMAP3_07581.1 huMAP3_08145.1 huMAP3_09654.1 huMAP3_10625.1 huMAP3_10659.1
HNRNPA0	huMAP3_01655.1 huMAP3_04752.1 huMAP3_05757.1 huMAP3_05898.1 huMAP3_06093.1 huMAP3_06297.1 huMAP3_07581.1 huMAP3_07846.1 huMAP3_08027.1 huMAP3_08281.1 huMAP3_09223.1 huMAP3_09281.1 huMAP3_09543.1 huMAP3_09654.1 huMAP3_10595.1 huMAP3_10625.1 huMAP3_10659.1 huMAP3_14523.1
HNRNPD	huMAP3_00427.1 huMAP3_01655.1 huMAP3_02726.1 huMAP3_03882.1 huMAP3_05757.1 huMAP3_05898.1 huMAP3_06093.1 huMAP3_07581.1 huMAP3_07846.1 huMAP3_08027.1 huMAP3_08281.1 huMAP3_09223.1 huMAP3_09281.1 huMAP3_09543.1 huMAP3_09654.1 huMAP3_10595.1 huMAP3_10625.1 huMAP3_10659.1 huMAP3_14523.1
HNRNPH3	huMAP3_01655.1 huMAP3_02726.1 huMAP3_03294.1 huMAP3_06093.1 huMAP3_07115.1 huMAP3_07225.1 huMAP3_08027.1 huMAP3_08281.1 huMAP3_08817.1 huMAP3_09223.1 huMAP3_09281.1 huMAP3_09543.1 huMAP3_09654.1 huMAP3_10595.1 huMAP3_10625.1 huMAP3_10659.1 huMAP3_12158.1 huMAP3_14523.1
HNRNPAB	huMAP3_01655.1 huMAP3_02207.1 huMAP3_04752.1 huMAP3_05898.1 huMAP3_06093.1 huMAP3_06192.1 huMAP3_07115.1 huMAP3_07581.1 huMAP3_07635.1 huMAP3_07846.1 huMAP3_08027.1 huMAP3_08281.1 huMAP3_09223.1 huMAP3_09281.1 huMAP3_09543.1 huMAP3_09654.1 huMAP3_10595.1 huMAP3_10625.1 huMAP3_10659.1 huMAP3_10937.1 huMAP3_14523.1
TNK1	huMAP3_04674.1 huMAP3_04770.1 huMAP3_05808.1 huMAP3_06058.1 huMAP3_06083.1 huMAP3_07225.1 huMAP3_07648.1 huMAP3_08027.1 huMAP3_09173.1 huMAP3_09654.1 huMAP3_10659.1 huMAP3_11516.1 huMAP3_12385.1
FAM120A	huMAP3_00582.1 huMAP3_02335.1 huMAP3_04752.1 huMAP3_04770.1 huMAP3_05807.1 huMAP3_06192.1 huMAP3_07115.1 huMAP3_07225.1 huMAP3_07846.1 huMAP3_08027.1 huMAP3_08281.1 huMAP3_09223.1 huMAP3_09281.1 huMAP3_09654.1 huMAP3_10625.1 huMAP3_10659.1
HNRNPA3	huMAP3_00427.1 huMAP3_01655.1 huMAP3_02726.1 huMAP3_05757.1 huMAP3_05898.1 huMAP3_06093.1 huMAP3_06671.1 huMAP3_07400.1 huMAP3_07581.1 huMAP3_07846.1 huMAP3_08027.1 huMAP3_08281.1 huMAP3_09223.1 huMAP3_09281.1 huMAP3_09543.1 huMAP3_09654.1 huMAP3_10595.1 huMAP3_10625.1 huMAP3_10659.1 huMAP3_13511.1 huMAP3_14523.1
HNRNPL	huMAP3_05721.1 huMAP3_06093.1 huMAP3_06671.1 huMAP3_07225.1 huMAP3_07581.1 huMAP3_07786.1 huMAP3_09654.1 huMAP3_10625.1 huMAP3_10659.1 huMAP3_13108.1
RBMX	huMAP3_04113.1 huMAP3_07272.1 huMAP3_07400.1 huMAP3_07581.1 huMAP3_08145.1 huMAP3_09654.1 huMAP3_10625.1 huMAP3_10659.1
HNRNPR	huMAP3_01167.1 huMAP3_02207.1 huMAP3_05931.1 huMAP3_06093.1 huMAP3_06297.1 huMAP3_07225.1 huMAP3_07581.1 huMAP3_07615.1 huMAP3_07635.1 huMAP3_09281.1 huMAP3_09654.1 huMAP3_10625.1 huMAP3_10659.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_09654.1

Complex Portal: CPX-16594