hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09655.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CSTB | Cystatin-B (CPI-B) (Liver thiol proteinase inhibitor) (Stefin-B) | 5 | UniProt NCBI |
| AIRE | Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein) | 5 | UniProt NCBI |
| CTSH | Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H (EC 3.4.22.16); Cathepsin H heavy chain; Cathepsin H light chain] | 5 | UniProt NCBI |
| CTSL | Procathepsin L (EC 3.4.22.15) (Cathepsin L1) (Major excreted protein) (MEP) [Cleaved into: Cathepsin L; Cathepsin L heavy chain; Cathepsin L light chain] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04210 | 0.0177164397058 | 0.5 | CTSH CTSL | Apoptosis |
| KEGG:04142 | 0.0186120295723 | 0.5 | CTSH CTSL | Lysosome |
| CORUM:1985 | 0.0249718442456 | 0.25 | AIRE | AIRE homodimer complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| AIRE | CTSH | 0.975 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CTSL | CTSH | 0.969 | 0.102 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| CSTB | CTSH | 0.951 | 0.134 | bioplex3_HEK293 bioplex3_WMM WMM_only |
| CTSL | CSTB | 0.355 | 0.086 | bioplex3_HEK293 bioplex () bioplex3_WMM |
Related Complexes