hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09660.1
Complex Portal: CPX-13969
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| OAZ1 | Ornithine decarboxylase antizyme 1 (AZ1) (ODC-Az) | 5 | UniProt NCBI |
| FOXA1 | Hepatocyte nuclear factor 3-alpha (HNF-3-alpha) (HNF-3A) (Forkhead box protein A1) (Transcription factor 3A) (TCF-3A) | 5 | UniProt NCBI |
| OAZ2 | Ornithine decarboxylase antizyme 2 (AZ2) (ODC-Az 2) | 4 | UniProt NCBI |
| AZIN2 | Antizyme inhibitor 2 (AzI2) (Arginine decarboxylase) (ADC) (ARGDC) (Ornithine decarboxylase-like protein) (ODC-like protein) (ornithine decarboxylase paralog) (ODC-p) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0042979 | 3.84440695359e-06 | 0.75 | AZIN2 OAZ1 OAZ2 | ornithine decarboxylase regulator activity |
| REAC:R-HSA-351202 | 3.87912301308e-05 | 0.75 | AZIN2 OAZ1 OAZ2 | Metabolism of polyamines |
| GO:0006595 | 0.000139871762976 | 0.75 | AZIN2 OAZ1 OAZ2 | polyamine metabolic process |
| GO:0006576 | 0.00751763182363 | 0.75 | AZIN2 OAZ1 OAZ2 | biogenic amine metabolic process |
| REAC:R-HSA-71291 | 0.007608748274 | 0.75 | AZIN2 OAZ1 OAZ2 | Metabolism of amino acids and derivatives |
| GO:0008073 | 0.00842684400117 | 0.5 | OAZ1 OAZ2 | ornithine decarboxylase inhibitor activity |
| REAC:R-HSA-350562 | 0.012504459305 | 0.5 | OAZ1 OAZ2 | Regulation of ornithine decarboxylase (ODC) |
| GO:0009308 | 0.0175369202004 | 0.75 | AZIN2 OAZ1 OAZ2 | amine metabolic process |
| CORUM:6642 | 0.049938562206 | 0.25 | OAZ1 | ODC-OAZ1-CCND1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| AZIN2 | OAZ2 | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| FOXA1 | AZIN2 | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| AZIN2 | OAZ1 | 0.992 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| OAZ1 | OAZ2 | 0.77 | bioplex_WMM bioplex3_WMM WMM_only | ||
| FOXA1 | OAZ2 | 0.572 | bioplex_WMM bioplex3_WMM WMM_only | ||
| FOXA1 | OAZ1 | 0.502 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes