hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_09707.1

Confidence: Moderate High

Genename	Protein Name	Uniprot Annotation Score	Links
GAGE2D	G antigen 2D (GAGE-2D) (Cancer/testis antigen 4.8) (CT4.8) (G antigen 8) (GAGE-8)	2	UniProt NCBI
CDYL2	Chromodomain Y-like protein 2 (CDY-like 2)	3	UniProt NCBI
ZNF644	Zinc finger protein 644 (Zinc finger motif enhancer-binding protein 2) (Zep-2)	5	UniProt NCBI
XAGE3	X antigen family member 3 (XAGE-3) (Cancer/testis antigen 12.3) (CT12.3) (G antigen family D member 4) (Placenta-specific gene 6 protein)	3	UniProt NCBI
MIER2	Mesoderm induction early response protein 2 (Mi-er2)	5	UniProt NCBI
WIZ	Protein Wiz (Widely-interspaced zinc finger-containing protein) (Zinc finger protein 803)	5	UniProt NCBI
ZNF462	Zinc finger protein 462 (Zinc finger PBX1-interacting protein) (ZFPIP)	5	UniProt NCBI
EHMT2	Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Lysine N-methyltransferase 1C) (Protein G9a)	5	UniProt NCBI
EHMT1	Histone-lysine N-methyltransferase EHMT1 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1) (GLP) (GLP1) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Lysine N-methyltransferase 1D)	5	UniProt NCBI
ADNP	Activity-dependent neuroprotector homeobox protein (Activity-dependent neuroprotective protein)	5	UniProt NCBI
XAGE2	X antigen family member 2 (XAGE-2) (Cancer/testis antigen 12.2) (CT12.2) (G antigen family D member 3)	3	UniProt NCBI
THOP1	Thimet oligopeptidase (EC 3.4.24.15) (Endopeptidase 24.15) (MP78)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:643	0.00122759131257	0.181818181818	EHMT2 EHMT1	CtBP core complex
GO:0001222	0.00127355706465	0.363636363636	ZNF644 EHMT1 WIZ EHMT2	transcription corepressor binding
CORUM:1194	0.00224781298839	0.181818181818	EHMT2 EHMT1	E2F-6 complex
CORUM:642	0.00462235583528	0.181818181818	EHMT2 EHMT1	CtBP complex
WP:WP4288	0.00912900259179	0.181818181818	EHMT2 EHMT1	MTHFR deficiency
REAC:R-HSA-6804760	0.020280338984	0.181818181818	EHMT2 EHMT1	Regulation of TP53 Activity through Methylation
GO:0001221	0.0255797286428	0.363636363636	ZNF644 EHMT1 WIZ EHMT2	transcription coregulator binding
KEGG:00310	0.0424043875552	0.181818181818	EHMT2 EHMT1	Lysine degradation
CORUM:860	0.049976851631	0.0909090909091	EHMT2	DNMT1-EHMT2-PCNA complex
CORUM:862	0.049976851631	0.0909090909091	EHMT2	DNMT1-EHMT2 complex

Edges

Protein 1	Protein 2	Score	ProteomeHD	Evidence
EHMT1	WIZ	1.0		hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () Malo fraction
ZNF644	EHMT2	1.0	0.104	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein ()
WIZ	XAGE2	1.0		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
ZNF644	WIZ	0.999		hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein ()
EHMT2	WIZ	0.999		hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein ()
XAGE3	WIZ	0.999		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
ZNF644	EHMT1	0.999	0.194	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein ()
ZNF644	XAGE2	0.999		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
EHMT1	XAGE2	0.999		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
XAGE3	EHMT1	0.999		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
EHMT2	XAGE2	0.999		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
XAGE3	EHMT2	0.999		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
EHMT2	EHMT1	0.998	0.708	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only
ZNF644	XAGE3	0.998		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
CDYL2	MIER2	0.997	0.086	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
ZNF462	XAGE2	0.996		bioplex3_WMM bioplex3_HCT116 WMM_only
ZNF462	WIZ	0.994		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
ZNF462	EHMT2	0.988	0.15	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
ZNF462	EHMT1	0.985	0.132	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
EHMT2	MIER2	0.982	0.104	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
EHMT2	ADNP	0.982	0.444	hein_WMM bioplex3_WMM youn_WMM fraction
EHMT1	MIER2	0.975	0.082	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
CDYL2	WIZ	0.974		hein_WMM bioplex_WMM bioplex3_WMM hein ()
EHMT1	ADNP	0.968	0.466	hein_WMM bioplex3_WMM youn_WMM WMM_only
EHMT1	GAGE2D	0.967		bioplex3_HEK293 bioplex3_WMM WMM_only
GAGE2D	WIZ	0.966		bioplex3_HEK293 bioplex3_WMM WMM_only
ZNF644	ADNP	0.963	0.19	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein ()
EHMT2	GAGE2D	0.959		bioplex3_HEK293 bioplex3_WMM WMM_only
THOP1	XAGE2	0.956		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
MIER2	WIZ	0.955		hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116
ZNF644	ZNF462	0.954	0.112	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
ZNF644	GAGE2D	0.914		bioplex3_HEK293 bioplex3_WMM WMM_only
ZNF644	MIER2	0.821	0.064	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
ADNP	WIZ	0.82		hein_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
EHMT2	CDYL2	0.719	0.094	hein_WMM bioplex_WMM bioplex3_WMM WMM_only
EHMT1	CDYL2	0.719	0.088	hein_WMM bioplex_WMM bioplex3_WMM WMM_only
ZNF644	CDYL2	0.467	0.096	hein_WMM bioplex_WMM bioplex3_WMM WMM_only
ADNP	MIER2	0.102	0.074	bioplex3_WMM WMM_only
ZNF462	THOP1	0.083	0.072	bioplex3_WMM WMM_only
ZNF462	ADNP	0.076	0.108	bioplex3_WMM WMM_only
WIZ	THOP1	0.057		bioplex_WMM bioplex3_WMM WMM_only
EHMT2	THOP1	0.037	0.058	bioplex_WMM bioplex3_WMM WMM_only
EHMT1	THOP1	0.022	0.04	bioplex_WMM bioplex3_WMM WMM_only
ZNF644	THOP1	0.021	0.034	bioplex_WMM bioplex3_WMM WMM_only
ADNP	THOP1	0.01	0.056	bioplex3_WMM WMM_only
MIER2	THOP1	0.009	0.058	bioplex3_WMM WMM_only

Related Complexes

Genename	Complexes
GAGE2D	huMAP3_00075.1 huMAP3_00560.1 huMAP3_02948.1 huMAP3_06802.1 huMAP3_07516.1 huMAP3_07706.1 huMAP3_07798.1 huMAP3_08057.1 huMAP3_09372.1 huMAP3_09707.1 huMAP3_11539.1 huMAP3_12929.1 huMAP3_15192.1
CDYL2	huMAP3_00462.1 huMAP3_02948.1 huMAP3_03637.1 huMAP3_07706.1 huMAP3_07798.1 huMAP3_08057.1 huMAP3_09372.1 huMAP3_09707.1 huMAP3_11539.1 huMAP3_15192.1
ZNF644	huMAP3_00075.1 huMAP3_00560.1 huMAP3_01874.1 huMAP3_06802.1 huMAP3_07516.1 huMAP3_07706.1 huMAP3_07798.1 huMAP3_08057.1 huMAP3_09046.1 huMAP3_09372.1 huMAP3_09707.1 huMAP3_11539.1 huMAP3_15192.1
XAGE3	huMAP3_00075.1 huMAP3_00560.1 huMAP3_01874.1 huMAP3_06802.1 huMAP3_07516.1 huMAP3_07706.1 huMAP3_07798.1 huMAP3_08057.1 huMAP3_09372.1 huMAP3_09707.1 huMAP3_13314.1 huMAP3_14462.1 huMAP3_15192.1
MIER2	huMAP3_00462.1 huMAP3_01287.1 huMAP3_02948.1 huMAP3_03637.1 huMAP3_07798.1 huMAP3_08057.1 huMAP3_09372.1 huMAP3_09707.1 huMAP3_10311.1 huMAP3_11539.1 huMAP3_15192.1
WIZ	huMAP3_00462.1 huMAP3_02948.1 huMAP3_06802.1 huMAP3_07516.1 huMAP3_07706.1 huMAP3_07798.1 huMAP3_08057.1 huMAP3_09372.1 huMAP3_09707.1 huMAP3_11539.1 huMAP3_15192.1
ZNF462	huMAP3_00075.1 huMAP3_00560.1 huMAP3_01874.1 huMAP3_06802.1 huMAP3_07516.1 huMAP3_07706.1 huMAP3_07798.1 huMAP3_08057.1 huMAP3_09372.1 huMAP3_09707.1 huMAP3_11539.1 huMAP3_15192.1
EHMT2	huMAP3_00075.1 huMAP3_00560.1 huMAP3_01874.1 huMAP3_06802.1 huMAP3_07516.1 huMAP3_07706.1 huMAP3_07798.1 huMAP3_08057.1 huMAP3_09372.1 huMAP3_09707.1 huMAP3_11539.1 huMAP3_14306.1 huMAP3_15192.1
EHMT1	huMAP3_00075.1 huMAP3_00560.1 huMAP3_01874.1 huMAP3_06802.1 huMAP3_07516.1 huMAP3_07706.1 huMAP3_07798.1 huMAP3_08057.1 huMAP3_08464.1 huMAP3_09232.1 huMAP3_09372.1 huMAP3_09707.1 huMAP3_10311.1 huMAP3_11539.1 huMAP3_15128.1 huMAP3_15192.1
ADNP	huMAP3_00075.1 huMAP3_00780.1 huMAP3_01874.1 huMAP3_04478.1 huMAP3_06802.1 huMAP3_07073.1 huMAP3_07706.1 huMAP3_07798.1 huMAP3_08464.1 huMAP3_09046.1 huMAP3_09071.1 huMAP3_09232.1 huMAP3_09582.1 huMAP3_09707.1 huMAP3_09963.1 huMAP3_10258.1 huMAP3_10311.1 huMAP3_11539.1
XAGE2	huMAP3_03729.1 huMAP3_06622.1 huMAP3_07516.1 huMAP3_09372.1 huMAP3_09707.1 huMAP3_10715.1 huMAP3_15192.1
THOP1	huMAP3_02114.1 huMAP3_03729.1 huMAP3_06622.1 huMAP3_09372.1 huMAP3_09707.1 huMAP3_10257.1 huMAP3_10715.1 huMAP3_13767.1 huMAP3_15192.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_09707.1