hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09708.1
Complex Portal: CPX-14143
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| OAZ2 | Ornithine decarboxylase antizyme 2 (AZ2) (ODC-Az 2) | 4 | UniProt NCBI |
| OAZ1 | Ornithine decarboxylase antizyme 1 (AZ1) (ODC-Az) | 5 | UniProt NCBI |
| FOXA1 | Hepatocyte nuclear factor 3-alpha (HNF-3-alpha) (HNF-3A) (Forkhead box protein A1) (Transcription factor 3A) (TCF-3A) | 5 | UniProt NCBI |
| AZIN2 | Antizyme inhibitor 2 (AzI2) (Arginine decarboxylase) (ADC) (ARGDC) (Ornithine decarboxylase-like protein) (ODC-like protein) (ornithine decarboxylase paralog) (ODC-p) | 5 | UniProt NCBI |
| AZIN1 | Antizyme inhibitor 1 (AZI) (AZI1) (Ornithine decarboxylase antizyme inhibitor) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0042979 | 6.57779757665e-10 | 0.8 | OAZ2 OAZ1 AZIN1 AZIN2 | ornithine decarboxylase regulator activity |
| GO:0006595 | 1.31622611039e-07 | 0.8 | OAZ2 OAZ1 AZIN1 AZIN2 | polyamine metabolic process |
| REAC:R-HSA-351202 | 1.5644237257e-07 | 0.8 | OAZ2 OAZ1 AZIN1 AZIN2 | Metabolism of polyamines |
| GO:0006576 | 3.02226820342e-05 | 0.8 | OAZ2 OAZ1 AZIN1 AZIN2 | biogenic amine metabolic process |
| REAC:R-HSA-350562 | 6.08725504416e-05 | 0.6 | OAZ2 OAZ1 AZIN1 | Regulation of ornithine decarboxylase (ODC) |
| GO:0009308 | 9.44983107329e-05 | 0.8 | OAZ2 OAZ1 AZIN1 AZIN2 | amine metabolic process |
| GO:0006596 | 0.000115261178119 | 0.6 | AZIN1 OAZ1 AZIN2 | polyamine biosynthetic process |
| REAC:R-HSA-71291 | 0.000184520892563 | 0.8 | OAZ2 OAZ1 AZIN1 AZIN2 | Metabolism of amino acids and derivatives |
| GO:0042401 | 0.00147736290187 | 0.6 | AZIN1 OAZ1 AZIN2 | biogenic amine biosynthetic process |
| GO:0009309 | 0.00169879277018 | 0.6 | AZIN1 OAZ1 AZIN2 | amine biosynthetic process |
| GO:0042978 | 0.00468200720083 | 0.4 | AZIN1 AZIN2 | ornithine decarboxylase activator activity |
| GO:1902269 | 0.00468200720083 | 0.4 | AZIN1 AZIN2 | positive regulation of polyamine transmembrane transport |
| GO:1902267 | 0.0140440992017 | 0.4 | AZIN1 AZIN2 | regulation of polyamine transmembrane transport |
| GO:0008073 | 0.0140440992017 | 0.4 | OAZ2 OAZ1 | ornithine decarboxylase inhibitor activity |
| GO:0033387 | 0.0140440992017 | 0.4 | AZIN1 AZIN2 | putrescine biosynthetic process from ornithine |
| GO:0009446 | 0.0280843539964 | 0.4 | AZIN1 AZIN2 | putrescine biosynthetic process |
| GO:0042176 | 0.0306592465565 | 0.8 | OAZ2 OAZ1 AZIN1 AZIN2 | regulation of protein catabolic process |
| GO:0009445 | 0.0468008499735 | 0.4 | AZIN1 AZIN2 | putrescine metabolic process |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| AZIN1 | OAZ1 | 0.999 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () | ||
| AZIN2 | OAZ2 | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| AZIN1 | OAZ2 | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| FOXA1 | AZIN2 | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| AZIN2 | OAZ1 | 0.992 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| OAZ1 | OAZ2 | 0.77 | bioplex_WMM bioplex3_WMM WMM_only | ||
| FOXA1 | OAZ2 | 0.572 | bioplex_WMM bioplex3_WMM WMM_only | ||
| FOXA1 | OAZ1 | 0.502 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes