hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_09719.1

Confidence: Moderate High

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Genename	Protein Name	Uniprot Annotation Score	Links
EEF2	Elongation factor 2 (EF-2) (EC 3.6.5.-)	5	UniProt NCBI
FBXL15	F-box/LRR-repeat protein 15 (F-box only protein 37)	5	UniProt NCBI
FBXL16	F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16)	4	UniProt NCBI
FBXL18	F-box/LRR-repeat protein 18 (F-box and leucine-rich repeat protein 18)	4	UniProt NCBI
FBXL8	F-box/LRR-repeat protein 8 (F-box and leucine-rich repeat protein 8) (F-box protein FBL8)	3	UniProt NCBI
FBXO31	F-box only protein 31	5	UniProt NCBI
FBXO9	F-box only protein 9 (Cross-immune reaction antigen 1) (Renal carcinoma antigen NY-REN-57)	5	UniProt NCBI
FBXW9	F-box/WD repeat-containing protein 9 (F-box and WD-40 domain-containing protein 9)	3	UniProt NCBI
KDM2A	Lysine-specific demethylase 2A (EC 1.14.11.27) (CXXC-type zinc finger protein 8) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina) (F-box/LRR-repeat protein 11) (JmjC domain-containing histone demethylation protein 1A) ([Histone-H3]-lysine-36 demethylase 1A)	5	UniProt NCBI
KDM2B	Lysine-specific demethylase 2B (EC 1.14.11.27) (CXXC-type zinc finger protein 2) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (Protein JEMMA) (Protein-containing CXXC domain 2) ([Histone-H3]-lysine-36 demethylase 1B)	5	UniProt NCBI

Showing 1 to 10 of 10 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0031146	1.18517073386e-09	0.666666666667	FBXL15 FBXL8 FBXO31 FBXL18 FBXL16 FBXO9	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
REAC:R-HSA-8951664	1.55222285173e-09	0.777777777778	FBXL15 FBXW9 FBXO31 FBXL18 FBXL8 FBXL16 FBXO9	Neddylation
REAC:R-HSA-983168	7.63393696818e-09	0.777777777778	FBXL15 FBXW9 FBXO31 FBXL18 FBXL8 FBXL16 FBXO9	Antigen processing: Ubiquitination & Proteasome degradation
GO:0019005	8.92743918497e-09	0.666666666667	FBXL15 FBXL8 FBXO31 FBXL18 FBXL16 FBXO9	SCF ubiquitin ligase complex
REAC:R-HSA-983169	3.21523862361e-08	0.777777777778	FBXL15 FBXW9 FBXO31 FBXL18 FBXL8 FBXL16 FBXO9	Class I MHC mediated antigen processing & presentation
REAC:R-HSA-1280218	3.05180298279e-06	0.777777777778	FBXL15 FBXW9 FBXO31 FBXL18 FBXL8 FBXL16 FBXO9	Adaptive Immune System
GO:0031461	8.92754588756e-06	0.666666666667	FBXL15 FBXL8 FBXO31 FBXL18 FBXL16 FBXO9	cullin-RING ubiquitin ligase complex
GO:0000151	0.000179732815089	0.666666666667	FBXL15 FBXL8 FBXO31 FBXL18 FBXL16 FBXO9	ubiquitin ligase complex
REAC:R-HSA-597592	0.000218137300916	0.777777777778	FBXL15 FBXW9 FBXO31 FBXL18 FBXL8 FBXL16 FBXO9	Post-translational protein modification
GO:0043161	0.000530475383283	0.666666666667	FBXL15 FBXL8 FBXO31 FBXL18 FBXL16 FBXO9	proteasome-mediated ubiquitin-dependent protein catabolic process

Showing 1 to 10 of 17 entries

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Protein 1	Protein 2	Score	ProteomeHD	Evidence
FBXO9	EEF2	0.998	0.252	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM
FBXL15	FBXL16	0.981		hein_WMM bioplex3_WMM WMM_only
FBXL8	FBXL15	0.981	0.06	hein_WMM bioplex3_WMM WMM_only
FBXL15	FBXO31	0.98		hein_WMM bioplex3_WMM WMM_only
FBXL8	FBXO9	0.978	0.13	hein_WMM bioplex3_WMM WMM_only
FBXL8	FBXO31	0.976		hein_WMM bioplex3_WMM WMM_only
FBXL15	FBXO9	0.974	0.066	hein_WMM bioplex3_WMM WMM_only
FBXO31	FBXO9	0.969		hein_WMM bioplex3_WMM WMM_only
FBXL8	KDM2A	0.961	0.036	hein_WMM bioplex3_WMM WMM_only
FBXL8	FBXL16	0.959		hein_WMM bioplex3_WMM WMM_only

Showing 1 to 10 of 36 entries

Related Complexes

Genename	Complexes
FBXO9	huMAP3_03548.1 huMAP3_09623.1 huMAP3_09719.1 huMAP3_14622.1
KDM2A	huMAP3_00161.1 huMAP3_00839.1 huMAP3_05528.1 huMAP3_09623.1 huMAP3_09719.1 huMAP3_14622.1
FBXL16	huMAP3_00161.1 huMAP3_00839.1 huMAP3_02984.1 huMAP3_05528.1 huMAP3_06552.1 huMAP3_09623.1 huMAP3_09719.1 huMAP3_09743.1 huMAP3_10333.1 huMAP3_13510.1 huMAP3_14622.1
FBXW9	huMAP3_00161.1 huMAP3_00839.1 huMAP3_05528.1 huMAP3_09623.1 huMAP3_09719.1 huMAP3_14584.1 huMAP3_14622.1
FBXL15	huMAP3_00161.1 huMAP3_00839.1 huMAP3_05528.1 huMAP3_09623.1 huMAP3_09719.1 huMAP3_14622.1
FBXL8	huMAP3_00161.1 huMAP3_00839.1 huMAP3_05528.1 huMAP3_09623.1 huMAP3_09719.1 huMAP3_14622.1
KDM2B	huMAP3_00161.1 huMAP3_00839.1 huMAP3_04542.1 huMAP3_05528.1 huMAP3_06040.1 huMAP3_08622.1 huMAP3_09623.1 huMAP3_09719.1 huMAP3_09756.1 huMAP3_10162.1 huMAP3_14051.1 huMAP3_14622.1
FBXL18	huMAP3_00161.1 huMAP3_00839.1 huMAP3_05528.1 huMAP3_09623.1 huMAP3_09719.1 huMAP3_14622.1
EEF2	huMAP3_03548.1 huMAP3_04733.1 huMAP3_09623.1 huMAP3_09711.1 huMAP3_09719.1 huMAP3_11132.1 huMAP3_12483.1 huMAP3_13947.1 huMAP3_14622.1
FBXO31	huMAP3_00161.1 huMAP3_00839.1 huMAP3_05528.1 huMAP3_09623.1 huMAP3_09719.1 huMAP3_14622.1