hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09720.1
Complex Portal: CPX-13198
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MTFR1L | Mitochondrial fission regulator 1-like | 4 | UniProt NCBI |
| MTFMT | Methionyl-tRNA formyltransferase, mitochondrial (MtFMT) (EC 2.1.2.9) | 5 | UniProt NCBI |
| MRPL12 | Large ribosomal subunit protein bL12m (39S ribosomal protein L12, mitochondrial) (L12mt) (MRP-L12) (5c5-2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0008347 | 0.0187458629677 | 0.666666666667 | MTFMT MRPL12 | Decreased activity of mitochondrial complex IV |
| REAC:R-HSA-5368286 | 0.0254089329805 | 0.666666666667 | MTFMT MRPL12 | Mitochondrial translation initiation |
| REAC:R-HSA-5368287 | 0.0290482612381 | 0.666666666667 | MTFMT MRPL12 | Mitochondrial translation |
| HP:0011923 | 0.0493566712329 | 0.666666666667 | MTFMT MRPL12 | Decreased activity of mitochondrial complex I |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MRPL12 | MTFR1L | 0.993 | 0.03 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| MRPL12 | MTFMT | 0.962 | 0.37 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| MTFR1L | MTFMT | 0.187 | 0.08 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes