hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09743.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FBXL16 | F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16) | 4 | UniProt NCBI |
| IGFBP5 | Insulin-like growth factor-binding protein 5 (IBP-5) (IGF-binding protein 5) (IGFBP-5) | 5 | UniProt NCBI |
| PPP2R2D | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PP2A subunit B isoform B55-delta) (PP2A subunit B isoform PR55-delta) (PP2A subunit B isoform R2-delta) (PP2A subunit B isoform delta) | 4 | UniProt NCBI |
| FOXS1 | Forkhead box protein S1 (Forkhead-like 18 protein) (Forkhead-related transcription factor 10) (FREAC-10) | 4 | UniProt NCBI |
| SERTAD1 | SERTA domain-containing protein 1 (CDK4-binding protein p34SEI1) (SEI-1) (p34(SEI-1)) (Transcriptional regulator interacting with the PHD-bromodomain 1) (TRIP-Br1) | 5 | UniProt NCBI |
| PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PP2A subunit B isoform B55-alpha) (PP2A subunit B isoform PR55-alpha) (PP2A subunit B isoform R2-alpha) (PP2A subunit B isoform alpha) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:05142 | 0.0273964025417 | 0.333333333333 | PPP2R2D PPP2R2A | Chagas disease |
| KEGG:03015 | 0.029291198851 | 0.333333333333 | PPP2R2D PPP2R2A | mRNA surveillance pathway |
| KEGG:04071 | 0.0374918580993 | 0.333333333333 | PPP2R2D PPP2R2A | Sphingolipid signaling pathway |
| KEGG:04660 | 0.0374918580993 | 0.333333333333 | PPP2R2D PPP2R2A | T cell receptor signaling pathway |
| KEGG:04728 | 0.0419636118509 | 0.333333333333 | PPP2R2D PPP2R2A | Dopaminergic synapse |
| KEGG:04152 | 0.045081780015 | 0.333333333333 | PPP2R2D PPP2R2A | AMPK signaling pathway |
| CORUM:5107 | 0.0499436884912 | 0.166666666667 | SERTAD1 | p34(SEI-1)-CDK4-CyclinD2 complex |
| KEGG:04261 | 0.0499639151988 | 0.333333333333 | PPP2R2D PPP2R2A | Adrenergic signaling in cardiomyocytes |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PPP2R2D | PPP2R2A | 1.0 | 0.754 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt hein () bioplex3_HCT116 gupta_WMM boldt_WMM |
| FBXL16 | IGFBP5 | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PPP2R2D | FOXS1 | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| FBXL16 | PPP2R2D | 0.987 | hein_WMM bioplex3_WMM hein () | |
| FOXS1 | PPP2R2A | 0.987 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| IGFBP5 | PPP2R2A | 0.982 | 0.07 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| PPP2R2D | SERTAD1 | 0.972 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SERTAD1 | PPP2R2A | 0.957 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| IGFBP5 | PPP2R2D | 0.951 | 0.034 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| FBXL16 | PPP2R2A | 0.927 | hein_WMM bioplex3_WMM hein () bioplex3_HCT116 |
Related Complexes