hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09749.1
Confidence: Moderate High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
LIFR | Leukemia inhibitory factor receptor (LIF receptor) (LIF-R) (CD antigen CD118) | 5 | UniProt   NCBI |
OSMR | Oncostatin-M-specific receptor subunit beta (Interleukin-31 receptor subunit beta) (IL-31 receptor subunit beta) (IL-31R subunit beta) (IL-31R-beta) (IL-31RB) | 5 | UniProt   NCBI |
KCNJ15 | ATP-sensitive inward rectifier potassium channel 15 (Inward rectifier K(+) channel Kir1.3) (Inward rectifier K(+) channel Kir4.2) (Potassium channel, inwardly rectifying subfamily J member 15) | 5 | UniProt   NCBI |
TMEM204 | Transmembrane protein 204 (Claudin-like protein 24) | 4 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-6788467 | 0.000798898068561 | 0.5 | LIFR OSMR | IL-6-type cytokine receptor ligand interactions |
  REAC:R-HSA-6783589 | 0.00175047124894 | 0.5 | LIFR OSMR | Interleukin-6 family signaling |
  WP:WP2374 | 0.0035028118218 | 0.5 | LIFR OSMR | Oncostatin M signaling pathway |
  WP:WP4538 | 0.00449637847065 | 0.5 | LIFR OSMR | Regulatory circuits of the STAT3 signaling pathway |
  GO:0004924 | 0.00842684400117 | 0.5 | LIFR OSMR | oncostatin-M receptor activity |
  GO:0038165 | 0.0168521501606 | 0.5 | LIFR OSMR | oncostatin-M-mediated signaling pathway |
  KEGG:04630 | 0.0211069184789 | 0.5 | LIFR OSMR | JAK-STAT signaling pathway |
  GO:0005127 | 0.042122686785 | 0.5 | LIFR OSMR | ciliary neurotrophic factor receptor binding |
  KEGG:04060 | 0.0475663770677 | 0.5 | LIFR OSMR | Cytokine-cytokine receptor interaction |
  CORUM:5579 | 0.049938562206 | 0.25 | LIFR | CNTF-CNTFR-gp130-LIFR complex |
  CORUM:5582 | 0.049938562206 | 0.25 | LIFR | LIFR-LIF-gp130 complex |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 TMEM204 |  OSMR | 0.972 |            | bioplex3_WMM     bioplex3_HCT116     WMM_only     |
 OSMR |  KCNJ15 | 0.968 |            | bioplex3_WMM     bioplex3_HCT116     WMM_only     |
 LIFR |  OSMR | 0.961 | 0.092           | hein_WMM     bioplex3_WMM     WMM_only     |
Related Complexes