hu.MAP 3.0: Complex View

Genename	Protein Name	Uniprot Annotation Score	Links
LIFR	Leukemia inhibitory factor receptor (LIF receptor) (LIF-R) (CD antigen CD118)	5	UniProt NCBI
OSMR	Oncostatin-M-specific receptor subunit beta (Interleukin-31 receptor subunit beta) (IL-31 receptor subunit beta) (IL-31R subunit beta) (IL-31R-beta) (IL-31RB)	5	UniProt NCBI
KCNJ15	ATP-sensitive inward rectifier potassium channel 15 (Inward rectifier K(+) channel Kir1.3) (Inward rectifier K(+) channel Kir4.2) (Potassium channel, inwardly rectifying subfamily J member 15)	5	UniProt NCBI
TMEM204	Transmembrane protein 204 (Claudin-like protein 24)	4	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-6788467	0.000798898068561	0.5	LIFR OSMR	IL-6-type cytokine receptor ligand interactions
REAC:R-HSA-6783589	0.00175047124894	0.5	LIFR OSMR	Interleukin-6 family signaling
WP:WP2374	0.0035028118218	0.5	LIFR OSMR	Oncostatin M signaling pathway
WP:WP4538	0.00449637847065	0.5	LIFR OSMR	Regulatory circuits of the STAT3 signaling pathway
GO:0004924	0.00842684400117	0.5	LIFR OSMR	oncostatin-M receptor activity
GO:0038165	0.0168521501606	0.5	LIFR OSMR	oncostatin-M-mediated signaling pathway
KEGG:04630	0.0211069184789	0.5	LIFR OSMR	JAK-STAT signaling pathway
GO:0005127	0.042122686785	0.5	LIFR OSMR	ciliary neurotrophic factor receptor binding
KEGG:04060	0.0475663770677	0.5	LIFR OSMR	Cytokine-cytokine receptor interaction
CORUM:5579	0.049938562206	0.25	LIFR	CNTF-CNTFR-gp130-LIFR complex
CORUM:5582	0.049938562206	0.25	LIFR	LIFR-LIF-gp130 complex

Protein 1	Protein 2	Score	ProteomeHD	Evidence
TMEM204	OSMR	0.972		bioplex3_WMM bioplex3_HCT116 WMM_only
OSMR	KCNJ15	0.968		bioplex3_WMM bioplex3_HCT116 WMM_only
LIFR	OSMR	0.961	0.092	hein_WMM bioplex3_WMM WMM_only

Genename	Complexes
LIFR	huMAP3_00440.1 huMAP3_01766.1 huMAP3_03527.1 huMAP3_09749.1 huMAP3_10077.1 huMAP3_11116.1 huMAP3_15148.1
OSMR	huMAP3_03006.1 huMAP3_08958.1 huMAP3_09749.1 huMAP3_11149.1 huMAP3_11605.1
KCNJ15	huMAP3_03006.1 huMAP3_04648.1 huMAP3_08958.1 huMAP3_09025.1 huMAP3_09749.1 huMAP3_13592.1 huMAP3_14049.1 huMAP3_14913.1
TMEM204	huMAP3_02078.1 huMAP3_03006.1 huMAP3_03859.1 huMAP3_04994.1 huMAP3_05434.1 huMAP3_05550.1 huMAP3_07383.1 huMAP3_08579.1 huMAP3_09144.1 huMAP3_09749.1 huMAP3_09880.1 huMAP3_10430.1 huMAP3_10877.1 huMAP3_11072.1 huMAP3_11149.1 huMAP3_13675.1