hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09751.1
Complex Portal: CPX-15777
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PLS1 | Plastin-1 (Intestine-specific plastin) (I-plastin) | 5 | UniProt NCBI |
| PTGR1 | Prostaglandin reductase 1 (PRG-1) (15-oxoprostaglandin 13-reductase) (EC 1.3.1.48) (Dithiolethione-inducible gene 1 protein) (D3T-inducible gene 1 protein) (DIG-1) (Leukotriene B4 12-hydroxydehydrogenase) (NAD(P)H-dependent alkenal/one oxidoreductase) (EC 1.3.1.74) | 5 | UniProt NCBI |
| STING1 | Stimulator of interferon genes protein (hSTING) (Endoplasmic reticulum interferon stimulator) (ERIS) (Mediator of IRF3 activation) (hMITA) (Transmembrane protein 173) | 5 | UniProt NCBI |
| DDAH1 | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (DDAH-1) (Dimethylarginine dimethylaminohydrolase 1) (EC 3.5.3.18) (DDAHI) (Dimethylargininase-1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7405 | 0.049938562206 | 0.25 | STING1 | TMEM173-TBK1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| STING1 | DDAH1 | 0.99 | 0.144 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PTGR1 | STING1 | 0.981 | 0.064 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PLS1 | STING1 | 0.966 | 0.084 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PLS1 | DDAH1 | 0.353 | 0.026 | bioplex_WMM bioplex3_WMM WMM_only | |
| PTGR1 | DDAH1 | 0.311 | 0.034 | bioplex3_WMM WMM_only | |
| PLS1 | PTGR1 | 0.046 | 0.028 | bioplex3_WMM WMM_only |
Related Complexes