hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09757.1
Complex Portal: CPX-22638
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TYW1B | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B (EC 4.1.3.44) (Radical S-adenosyl methionine and flavodoxin domain-containing protein 2) (tRNA wybutosine-synthesizing protein 1 homolog B) | 4 | UniProt NCBI |
| TNIK | TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1) | 5 | UniProt NCBI |
| MINK1 | Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4537 | 0.000193548942551 | 0.666666666667 | TNIK MINK1 | Hippo YAP signaling |
| REAC:R-HSA-2559580 | 0.0384822430974 | 0.666666666667 | TNIK MINK1 | Oxidative Stress Induced Senescence |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MINK1 | TNIK | 0.996 | 0.14 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| MINK1 | TYW1B | 0.955 | bioplex_WMM bioplex3_WMM WMM_only | ||
| TYW1B | TNIK | 0.011 | bioplex3_WMM WMM_only |
Related Complexes