hu.MAP 3.0: Complex View

Human Protein Complex Map

Genename	Protein Name	Uniprot Annotation Score	Links
DDOST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (DDOST 48 kDa subunit) (Oligosaccharyl transferase 48 kDa subunit)	5	UniProt NCBI
ATP2A3	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (SERCA3) (SR Ca(2+)-ATPase 3) (EC 7.2.2.10) (Calcium pump 3)	5	UniProt NCBI
OSTC	Oligosaccharyltransferase complex subunit OSTC (Hydrophobic protein HSF-28)	5	UniProt NCBI
FAAH	Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Fatty acid ester hydrolase) (EC 3.1.1.-) (Oleamide hydrolase 1)	5	UniProt NCBI
ATP2A1	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (SERCA1) (SR Ca(2+)-ATPase 1) (EC 7.2.2.10) (Calcium pump 1) (Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)	5	UniProt NCBI
B3GALT6	Beta-1,3-galactosyltransferase 6 (Beta-1,3-GalTase 6) (Beta3Gal-T6) (Beta3GalT6) (EC 2.4.1.134) (GAG GalTII) (Galactosyltransferase II) (Galactosylxylosylprotein 3-beta-galactosyltransferase) (UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6)	5	UniProt NCBI
TEX2	Testis-expressed protein 2 (Transmembrane protein 96)	4	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-418359	0.00209171533568	0.285714285714	ATP2A1 ATP2A3	Reduction of cytosolic Ca++ levels
REAC:R-HSA-1912420	0.00516516478082	0.285714285714	ATP2A1 ATP2A3	Pre-NOTCH Processing in Golgi
KEGG:00513	0.00793622460548	0.285714285714	OSTC DDOST	Various types of N-glycan biosynthesis
REAC:R-HSA-418360	0.00959557699108	0.285714285714	ATP2A1 ATP2A3	Platelet calcium homeostasis
GO:0030899	0.00983221512175	0.285714285714	ATP2A1 ATP2A3	calcium-dependent ATPase activity
KEGG:00510	0.0114560548	0.285714285714	OSTC DDOST	N-Glycan biosynthesis
KEGG:05412	0.0230300913808	0.285714285714	ATP2A1 ATP2A3	Arrhythmogenic right ventricular cardiomyopathy
GO:0031984	0.023071085069	0.857142857143	ATP2A1 OSTC DDOST FAAH ATP2A3 B3GALT6	organelle subcompartment
KEGG:04260	0.0258170059595	0.285714285714	ATP2A1 ATP2A3	Cardiac muscle contraction
KEGG:04972	0.0258170059595	0.285714285714	ATP2A1 ATP2A3	Pancreatic secretion
REAC:R-HSA-936837	0.0265716665994	0.285714285714	ATP2A1 ATP2A3	Ion transport by P-type ATPases
KEGG:05410	0.0287602683365	0.285714285714	ATP2A1 ATP2A3	Hypertrophic cardiomyopathy
KEGG:05414	0.0287602683365	0.285714285714	ATP2A1 ATP2A3	Dilated cardiomyopathy
REAC:R-HSA-5578775	0.030972755234	0.285714285714	ATP2A1 ATP2A3	Ion homeostasis
CORUM:6514	0.0499958217778	0.142857142857	ATP2A1	SLN-ATP2A1 complex
CORUM:6515	0.0499958217778	0.142857142857	ATP2A1	SLN-PLN-SERCA1A complex

Protein 1	Protein 2	Score	ProteomeHD	Evidence
ATP2A1	ATP2A3	0.993		bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
TEX2	ATP2A3	0.98		bioplex3_WMM bioplex3_HCT116 WMM_only
OSTC	ATP2A3	0.979		bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
DDOST	ATP2A3	0.976		bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM WMM_only
FAAH	ATP2A3	0.975		bioplex3_WMM bioplex3_HCT116 WMM_only
ATP2A3	B3GALT6	0.972		bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
OSTC	B3GALT6	0.88	0.102	bioplex_WMM bioplex3_WMM WMM_only
ATP2A1	OSTC	0.836	0.172	bioplex3_HEK293 bioplex3_WMM WMM_only
FAAH	B3GALT6	0.587	0.058	bioplex3_WMM WMM_only
ATP2A1	B3GALT6	0.561	0.196	bioplex3_HEK293 bioplex3_WMM WMM_only
FAAH	OSTC	0.343	0.0734	bioplex3_WMM WMM_only
TEX2	OSTC	0.238	0.088	bioplex3_WMM WMM_only
DDOST	FAAH	0.215	0.1732	bioplex3_WMM WMM_only
FAAH	TEX2	0.214	0.056	bioplex3_WMM WMM_only
DDOST	ATP2A1	0.19	0.554	bioplex3_HEK293 bioplex_WMM bioplex3_WMM gupta_WMM WMM_only
ATP2A1	TEX2	0.159	0.174	bioplex3_WMM WMM_only
TEX2	B3GALT6	0.154	0.076	bioplex3_WMM WMM_only
FAAH	ATP2A1	0.099	0.112	bioplex3_WMM WMM_only
DDOST	B3GALT6	0.078	0.194	bioplex_WMM bioplex3_WMM WMM_only
DDOST	OSTC	0.011	0.718	bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only
DDOST	TEX2	0.01	0.126	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM

Genename	Complexes
DDOST	huMAP3_00921.1 huMAP3_05358.1 huMAP3_05375.1 huMAP3_06187.1 huMAP3_06663.1 huMAP3_07211.1 huMAP3_08559.1 huMAP3_08612.1 huMAP3_09763.1 huMAP3_09893.1 huMAP3_10071.1
ATP2A3	huMAP3_05358.1 huMAP3_05938.1 huMAP3_07353.1 huMAP3_08559.1 huMAP3_09763.1
OSTC	huMAP3_04067.1 huMAP3_05358.1 huMAP3_05938.1 huMAP3_06285.1 huMAP3_08559.1 huMAP3_08983.1 huMAP3_09763.1 huMAP3_11890.1
FAAH	huMAP3_01648.1 huMAP3_05358.1 huMAP3_08559.1 huMAP3_09763.1 huMAP3_11294.1 huMAP3_11507.1 huMAP3_11562.1 huMAP3_11955.1 huMAP3_15113.1
ATP2A1	huMAP3_01703.1 huMAP3_09763.1
B3GALT6	huMAP3_08559.1 huMAP3_09763.1 huMAP3_11833.1
TEX2	huMAP3_01854.1 huMAP3_05065.1 huMAP3_05358.1 huMAP3_05938.1 huMAP3_07084.1 huMAP3_08559.1 huMAP3_09313.1 huMAP3_09763.1 huMAP3_12290.1 huMAP3_12718.1