hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09764.1
Complex Portal: CPX-16191
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CLIC3 | Chloride intracellular channel protein 3 | 5 | UniProt NCBI |
| PAN3 | PAN2-PAN3 deadenylation complex subunit PAN3 (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 3) (PAN deadenylation complex subunit 3) | 5 | UniProt NCBI |
| PAN2 | PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (EC 3.1.13.4) (Inactive ubiquitin carboxyl-terminal hydrolase 52) (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 2) (PAN deadenylation complex subunit 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0031251 | 0.00140460216025 | 0.666666666667 | PAN3 PAN2 | PAN complex |
| REAC:R-HSA-429947 | 0.00188000535098 | 0.666666666667 | PAN3 PAN2 | Deadenylation of mRNA |
| KEGG:03018 | 0.0019996401701 | 0.666666666667 | PAN3 PAN2 | RNA degradation |
| REAC:R-HSA-429914 | 0.0101009261622 | 0.666666666667 | PAN3 PAN2 | Deadenylation-dependent mRNA decay |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PAN2 | PAN3 | 0.996 | 0.19 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only | |
| PAN3 | CLIC3 | 0.986 | 0.056 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PAN2 | CLIC3 | 0.327 | 0.04 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes